{"id":"https://openalex.org/W4410769596","doi":"https://doi.org/10.1016/j.jid.2025.05.009","title":"Post-Translational Regulation of Transcription Factor KROX20 in Epithelial Stem Cells","display_name":"Post-Translational Regulation of Transcription Factor KROX20 in Epithelial Stem Cells","publication_year":2025,"publication_date":"2025-05-27","ids":{"openalex":"https://openalex.org/W4410769596","doi":"https://doi.org/10.1016/j.jid.2025.05.009","pmid":"https://pubmed.ncbi.nlm.nih.gov/40441290","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12210152"},"language":"en","primary_location":{"id":"doi:10.1016/j.jid.2025.05.009","doi":"https://doi.org/10.1016/j.jid.2025.05.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jid.2025.05.009","pdf_url":null,"source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12210152/pdf/nihms-2085413.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016147616","display_name":"Elnaz Ghotbi","orcid":"https://orcid.org/0000-0002-6568-9553","observed_orcids":["https://orcid.org/0000-0002-6568-9553"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elnaz Ghotbi","raw_affiliation_strings":["Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA"],"raw_orcid":"https://orcid.org/0000-0002-6568-9553","affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081166884","display_name":"Edem Tchegnon","orcid":"https://orcid.org/0000-0003-2874-6472","observed_orcids":["https://orcid.org/0000-0003-2874-6472"]},"institutions":[{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edem Tchegnon","raw_affiliation_strings":["Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA"],"raw_orcid":"https://orcid.org/0000-0003-2874-6472","affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA","institution_ids":["https://openalex.org/I867280407"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100718157","display_name":"Yumeng Zhang","orcid":"https://orcid.org/0000-0001-5220-0491","observed_orcids":["https://orcid.org/0000-0001-5220-0491"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yumeng Zhang","raw_affiliation_strings":["Department of Dermatology, University of Virginia School of Medicine, Charlottesville, Virginia, USA"],"raw_orcid":"https://orcid.org/0000-0001-5220-0491","affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Virginia School of Medicine, Charlottesville, Virginia, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055460395","display_name":"Ren\u00e9e M. McKay","orcid":"https://orcid.org/0000-0001-5976-1996","observed_orcids":["https://orcid.org/0000-0001-5976-1996"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Renee M. McKay","raw_affiliation_strings":["Department of Dermatology, University of Virginia School of Medicine, Charlottesville, Virginia, USA"],"raw_orcid":"https://orcid.org/0000-0001-5976-1996","affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Virginia School of Medicine, Charlottesville, Virginia, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064595278","display_name":"Lu Q. Le","orcid":"https://orcid.org/0000-0003-2817-5382","observed_orcids":["https://orcid.org/0000-0003-2817-5382"]},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]},{"id":"https://openalex.org/I867280407","display_name":"The University of Texas Southwestern Medical Center","ror":"https://ror.org/05byvp690","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I867280407"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lu Q. Le","raw_affiliation_strings":["Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Dermatology, University of Virginia School of Medicine, Charlottesville, Virginia, USA. Electronic address: bkn6qd@uvahealth.org"],"raw_orcid":"https://orcid.org/0000-0003-2817-5382","affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Department of Dermatology, University of Virginia School of Medicine, Charlottesville, Virginia, USA. Electronic address: bkn6qd@uvahealth.org","institution_ids":["https://openalex.org/I51556381","https://openalex.org/I867280407"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5064595278"],"corresponding_institution_ids":["https://openalex.org/I51556381","https://openalex.org/I867280407"],"apc_list":{"value":3800,"currency":"USD","value_usd":3800},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"145","issue":"12","first_page":"3240","last_page":"3243.e3"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/krox20","display_name":"Krox20","score":0.996999979019165},{"id":"https://openalex.org/keywords/zinc-finger-transcription-factor","display_name":"zinc finger transcription factor","score":0.8970000147819519},{"id":"https://openalex.org/keywords/epithelial-stem-cells","display_name":"epithelial stem cells","score":0.890999972820282},{"id":"https://openalex.org/keywords/post-translational-regulation","display_name":"post-translational regulation","score":0.9490000009536743},{"id":"https://openalex.org/keywords/hair-follicle-stem-cells","display_name":"hair follicle stem cells","score":0.8080000281333923},{"id":"https://openalex.org/keywords/meibomian-glands","display_name":"meibomian glands","score":0.9049999713897705},{"id":"https://openalex.org/keywords/lentiviral-overexpression","display_name":"lentiviral overexpression","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.706943154335022},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6216875910758972},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5571388006210327},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4374634623527527},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.4208183288574219},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3440413177013397},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2752237021923065},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1671343445777893},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jid.2025.05.009","doi":"https://doi.org/10.1016/j.jid.2025.05.009","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jid.2025.05.009","pdf_url":null,"source":{"id":"https://openalex.org/S28607811","display_name":"Journal of Investigative Dermatology","issn_l":"0022-202X","issn":["0022-202X","1523-1747"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Investigative Dermatology","raw_type":"journal-article"},{"id":"pmid:40441290","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40441290","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of investigative dermatology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12210152","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12210152/pdf/nihms-2085413.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Invest Dermatol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12210152","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12210152/pdf/nihms-2085413.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Invest Dermatol","raw_type":"Text"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger","score":0.5199999809265137}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6515237349","display_name":"Dermatology Research Training Program","funder_award_id":"T32AR065969","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"},{"id":"https://openalex.org/G9000871519","display_name":"Epithelial stem cells in Meibomian gland development and homeostasis","funder_award_id":"R01EY033344","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320306155","display_name":"Cancer Research Institute","ror":"https://ror.org/02f3xk561"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W2079988105","https://openalex.org/W2286099491","https://openalex.org/W2611269800","https://openalex.org/W2615853094","https://openalex.org/W3197444204","https://openalex.org/W4403096688"],"related_works":["https://openalex.org/W4285984723","https://openalex.org/W2942225113","https://openalex.org/W4366184019","https://openalex.org/W3153507741","https://openalex.org/W4412110629","https://openalex.org/W3154754510","https://openalex.org/W2056083261","https://openalex.org/W2187036357","https://openalex.org/W2799821853","https://openalex.org/W158449578"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2025-05-28T00:00:00"}
