{"id":"https://openalex.org/W4410544690","doi":"https://doi.org/10.1016/j.biomaterials.2025.123430","title":"Graphene-polymer Nanofibers Enable Optically Induced Electrical Maturation in Stem Cell-Derived Cardiomyocytes and Brain Organoids","display_name":"Graphene-polymer Nanofibers Enable Optically Induced Electrical Maturation in Stem Cell-Derived Cardiomyocytes and Brain Organoids","publication_year":2024,"publication_date":"2024-12-15","ids":{"openalex":"https://openalex.org/W4410544690","doi":"https://doi.org/10.1016/j.biomaterials.2025.123430","pmid":"https://pubmed.ncbi.nlm.nih.gov/40435813","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12893844"},"language":"en","primary_location":{"id":"doi:10.1016/j.biomaterials.2025.123430","doi":"https://doi.org/10.1016/j.biomaterials.2025.123430","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2025.123430","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.biomaterials.2025.123430","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027426739","display_name":"Erin LaMontagne","orcid":"https://orcid.org/0000-0003-0017-8223","observed_orcids":["https://orcid.org/0000-0003-0017-8223"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Erin LaMontagne","raw_affiliation_strings":["Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, 92093, USA"],"raw_orcid":"https://orcid.org/0000-0003-0017-8223","affiliations":[{"raw_affiliation_string":"Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Alex Savchenko","orcid":"https://orcid.org/0000-0002-9330-1309","observed_orcids":["https://orcid.org/0000-0002-9330-1309"]},"institutions":[{"id":"https://openalex.org/I4387155630","display_name":"Naos Marine and Molecular Laboratories","ror":"https://ror.org/007yfgf06","country_code":"PA","type":"facility","lineage":["https://openalex.org/I103187081","https://openalex.org/I128212801","https://openalex.org/I4387155630"]}],"countries":["PA"],"is_corresponding":false,"raw_author_name":"Alex Savchenko","raw_affiliation_strings":["Nanotools Bioscience, La Jolla, CA, 92093, USA"],"raw_orcid":"https://orcid.org/0000-0002-9330-1309","affiliations":[{"raw_affiliation_string":"Nanotools Bioscience, La Jolla, CA, 92093, USA","institution_ids":["https://openalex.org/I4387155630"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084883128","display_name":"Gisselle Gonzalez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gisselle Gonzalez","raw_affiliation_strings":["Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, 92093, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004390474","display_name":"Ritwik Vatsyayan","orcid":"https://orcid.org/0000-0001-9192-3836","observed_orcids":["https://orcid.org/0000-0001-9192-3836"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ritwik Vatsyayan","raw_affiliation_strings":["Department of Electrical and Computer Engineering, La Jolla, CA, 92093, USA"],"raw_orcid":"https://orcid.org/0000-0001-9192-3836","affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024659330","display_name":"Blanca Martin-Burgos","orcid":"https://orcid.org/0000-0002-1388-9123","observed_orcids":["https://orcid.org/0000-0002-1388-9123"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Blanca Martin-Burgos","raw_affiliation_strings":["Neurosciences Graduate Program, La Jolla, CA, 92093, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurosciences Graduate Program, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Francesca Puppo","orcid":"https://orcid.org/0000-0003-2399-4143","observed_orcids":["https://orcid.org/0000-0003-2399-4143"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Francesca Puppo","raw_affiliation_strings":["Department of Pediatrics, La Jolla, CA, 92093, USA"],"raw_orcid":"https://orcid.org/0000-0003-2399-4143","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090223287","display_name":"Diogo Biagi","orcid":"https://orcid.org/0000-0002-5872-6133","observed_orcids":["https://orcid.org/0000-0002-5872-6133"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Diogo Biagi","raw_affiliation_strings":["Department of Pediatrics, La Jolla, CA, 92093, USA"],"raw_orcid":"https://orcid.org/0000-0002-5872-6133","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029426053","display_name":"F\u00e1bio Papes","orcid":"https://orcid.org/0000-0001-5034-4088","observed_orcids":["https://orcid.org/0000-0001-5034-4088"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Fabio Papes","raw_affiliation_strings":["Department of Pediatrics, La Jolla, CA, 92093, USA"],"raw_orcid":"https://orcid.org/0000-0001-5034-4088","affiliations":[{"raw_affiliation_string":"Department of Pediatrics, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045100404","display_name":"Shadi A. Dayeh","orcid":"https://orcid.org/0000-0002-1756-1774","observed_orcids":["https://orcid.org/0000-0002-1756-1774"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shadi A. Dayeh","raw_affiliation_strings":["Department of Electrical and Computer Engineering, La Jolla, CA, 92093, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, La Jolla, CA, 92093, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048323500","display_name":"Alysson Renato Muotri","orcid":"https://orcid.org/0000-0003-0867-2875","observed_orcids":["https://orcid.org/0000-0003-0867-2875"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alysson R. Muotri","raw_affiliation_strings":["Neurosciences Graduate Program, La Jolla, CA, 92093, USA; Department of Pediatrics, La Jolla, CA, 92093, USA; Departmentof Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA; Sanford Stem Cell Institute, La Jolla, CA, 92037, USA. Electronic address: muotri@ucsd.edu"],"raw_orcid":"https://orcid.org/0000-0003-0867-2875","affiliations":[{"raw_affiliation_string":"Neurosciences Graduate Program, La Jolla, CA, 92093, USA; Department of Pediatrics, La Jolla, CA, 92093, USA; Departmentof Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, 92093, USA; Sanford Stem Cell Institute, La Jolla, CA, 92037, USA. Electronic address: muotri@ucsd.edu","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039405858","display_name":"Adam Jeffrey Engler","orcid":"https://orcid.org/0000-0003-1642-5380","observed_orcids":["https://orcid.org/0000-0003-1642-5380"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Adam J. Engler","raw_affiliation_strings":["Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, 92093, USA; Sanford Stem Cell Institute, La Jolla, CA, 92037, USA. Electronic address: aengler@ucsd.edu"],"raw_orcid":"https://orcid.org/0000-0003-1642-5380","affiliations":[{"raw_affiliation_string":"Shu Chien-Gene Lay Department of Bioengineering, La Jolla, CA, 92093, USA; Sanford Stem Cell Institute, La Jolla, CA, 92037, USA. Electronic address: aengler@ucsd.edu","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5039405858","https://openalex.org/A5048323500"],"corresponding_institution_ids":["https://openalex.org/I36258959"],"apc_list":{"value":4740,"currency":"USD","value_usd":4740},"apc_paid":null,"fwci":1.8117,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.86117601,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"323","issue":null,"first_page":"123430","last_page":"123430"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.5160999894142151,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.5160999894142151,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10729","display_name":"Electrospun Nanofibers in Biomedical Applications","score":0.305400013923645,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.11129999905824661,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/graphene-oxide","display_name":"graphene oxide","score":0.7009999752044678},{"id":"https://openalex.org/keywords/polymer-nanofibers","display_name":"polymer nanofibers","score":0.9340000152587891},{"id":"https://openalex.org/keywords/electrospinning","display_name":"electrospinning","score":0.9589999914169312},{"id":"https://openalex.org/keywords/optogenetics","display_name":"optogenetics","score":0.6970000267028809},{"id":"https://openalex.org/keywords/human-pluripotent-stem-cell-derived-cardiomyocytes","display_name":"human pluripotent stem cell-derived cardiomyocytes","score":0.8949999809265137},{"id":"https://openalex.org/keywords/stem-cell-derived-neurons","display_name":"stem cell-derived neurons","score":0.7689999938011169},{"id":"https://openalex.org/keywords/brain-organoids","display_name":"brain organoids","score":0.9980000257492065},{"id":"https://openalex.org/keywords/calcium-handling","display_name":"calcium handling","score":0.9290000200271606},{"id":"https://openalex.org/keywords/retinal-differentiation","display_name":"retinal differentiation","score":0.9779999852180481},{"id":"https://openalex.org/keywords/electrical-conductivity","display_name":"electrical conductivity","score":0.9049999713897705}],"concepts":[{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.8169711828231812},{"id":"https://openalex.org/C31695470","wikidata":"https://www.wikidata.org/wiki/Q11293125","display_name":"Organoid","level":2,"score":0.8090266585350037},{"id":"https://openalex.org/C91129048","wikidata":"https://www.wikidata.org/wiki/Q594196","display_name":"Nanofiber","level":2,"score":0.7411968111991882},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6240241527557373},{"id":"https://openalex.org/C30080830","wikidata":"https://www.wikidata.org/wiki/Q169917","display_name":"Graphene","level":2,"score":0.5670220851898193},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.5626233816146851},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.3765535056591034},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3461367189884186},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.323641836643219},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.1725146472454071},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.16652271151542664},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09060126543045044},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.08260783553123474}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D002118","descriptor_name":"Calcium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002454","descriptor_name":"Cell Differentiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004553","descriptor_name":"Electric Conductivity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006108","descriptor_name":"Graphite","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009940","descriptor_name":"Organoids","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D032383","descriptor_name":"Myocytes, Cardiac","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D039904","descriptor_name":"Pluripotent Stem Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D057139","descriptor_name":"Nanofibers","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":true},{"descriptor_ui":"D057139","descriptor_name":"Nanofibers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.biomaterials.2025.123430","doi":"https://doi.org/10.1016/j.biomaterials.2025.123430","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2025.123430","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"journal-article"},{"id":"doi:10.1101/2024.12.09.627640","doi":"https://doi.org/10.1101/2024.12.09.627640","is_oa":false,"landing_page_url":"https://doi.org/10.1101/2024.12.09.627640","pdf_url":null,"source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:12893844","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12893844/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12893844/pdf/nihms-2134615.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Text"},{"id":"pmid:40435813","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40435813","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomaterials","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.biomaterials.2025.123430","doi":"https://doi.org/10.1016/j.biomaterials.2025.123430","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.biomaterials.2025.123430","pdf_url":null,"source":{"id":"https://openalex.org/S163807576","display_name":"Biomaterials","issn_l":"0142-9612","issn":["0142-9612","1878-5905"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Biomaterials","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1224366128","display_name":null,"funder_award_id":"S10 OD026929","funder_id":"https://openalex.org/F4320306171","funder_display_name":"California Institute for Regenerative Medicine"},{"id":"https://openalex.org/G1330273324","display_name":null,"funder_award_id":"12804","funder_id":"https://openalex.org/F4320306171","funder_display_name":"California Institute for Regenerative Medicine"},{"id":"https://openalex.org/G1476237564","display_name":null,"funder_award_id":"#S10 OD026929","funder_id":"https://openalex.org/F4320332603","funder_display_name":"University of California, San Diego"},{"id":"https://openalex.org/G2108803891","display_name":null,"funder_award_id":"R01NS116802","funder_id":"https://openalex.org/F4320332603","funder_display_name":"University of California, San Diego"},{"id":"https://openalex.org/G3306396600","display_name":"Illumina NovaSeq 6000 Sequencing System","funder_award_id":"1s10od026929-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3640495024","display_name":"Interdisciplinary Stem Cell Training Grant at UCSD III","funder_award_id":"EDUC4-12804","funder_id":"https://openalex.org/F4320306171","funder_display_name":"California Institute for Regenerative Medicine"},{"id":"https://openalex.org/G41655884","display_name":null,"funder_award_id":"1R01ES033636","funder_id":"https://openalex.org/F4320332603","funder_display_name":"University of California, San Diego"},{"id":"https://openalex.org/G4334509389","display_name":null,"funder_award_id":"ECCS-2025752","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4951853063","display_name":null,"funder_award_id":"1R01MH128365","funder_id":"https://openalex.org/F4320332603","funder_display_name":"University of California, San Diego"},{"id":"https://openalex.org/G5234461297","display_name":"NNCI: San Diego Nanotechnology Infrastructure (SDNI)","funder_award_id":"2025752","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5309698474","display_name":"Enabling non-genetic activity-driven maturation of iPSC-derived neurons","funder_award_id":"DISC2-13483","funder_id":"https://openalex.org/F4320306171","funder_display_name":"California Institute for Regenerative Medicine"},{"id":"https://openalex.org/G5323515921","display_name":"Brain pathology and function in a chronic mouse model of ZIKV transmission","funder_award_id":"R01NS105969","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G5344493716","display_name":null,"funder_award_id":"2025752","funder_id":"https://openalex.org/F4320337392","funder_display_name":"Division of Electrical, Communications and Cyber Systems"},{"id":"https://openalex.org/G5464304131","display_name":null,"funder_award_id":"R56 MH128365","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G5478983490","display_name":"Biophysical Interrogation of Signals that Drive GBM Invasion","funder_award_id":"R01NS116802","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G574849366","display_name":null,"funder_award_id":"1R43MH124563","funder_id":"https://openalex.org/F4320332603","funder_display_name":"University of California, San Diego"},{"id":"https://openalex.org/G6113046864","display_name":"Cortical organoid models to study autism-associated 16p.11.2.CNV","funder_award_id":"1r56mh128365-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7200115907","display_name":"Integrative functional genomic study of pathways impacted by recurrent autism CNV","funder_award_id":"R01MH108528","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G7912428907","display_name":"Non-genetic optical stimulation platform for the next-generation neuroscience drug discovery assays","funder_award_id":"R43MH124563","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G7978076427","display_name":null,"funder_award_id":"U01 FD006676","funder_id":"https://openalex.org/F4320332163","funder_display_name":"U.S. Food and Drug Administration"},{"id":"https://openalex.org/G8638431675","display_name":"Consortium Led Evaluation of Integrated Human-Relevant Approaches to Identify Drug Induced Cardiovascular Liabilities","funder_award_id":"5u01fd006676-02","funder_id":"https://openalex.org/F4320332163","funder_display_name":"U.S. Food and Drug Administration"},{"id":"https://openalex.org/G8734224423","display_name":null,"funder_award_id":"ECCS-2025752","funder_id":"https://openalex.org/F4320337392","funder_display_name":"Division of Electrical, Communications and Cyber Systems"},{"id":"https://openalex.org/G9000144769","display_name":null,"funder_award_id":"R01NS123642","funder_id":"https://openalex.org/F4320332603","funder_display_name":"University of California, San Diego"},{"id":"https://openalex.org/G9000888528","display_name":"Proteogenetics of Autism Spectrum Disorders","funder_award_id":"R01MH100175","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000888867","display_name":"Investigation of Pitt-Hopkins Syndrome pathophysiology using a human model","funder_award_id":"R01MH123828","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000893105","display_name":"Establishment of a causal link between AD and L1 retrotransposons","funder_award_id":"R01AG078959","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G9000905869","display_name":"Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and Autism","funder_award_id":"R01MH127077","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G9000909204","display_name":"Investigating neurodevelopmental toxicity of perfluoroalkyl acids and their derivatives in human brain organoids models","funder_award_id":"R01ES033636","funder_id":"https://openalex.org/F4320337361","funder_display_name":"National Institute of Environmental Health Sciences"},{"id":"https://openalex.org/G9000910526","display_name":"The Impact of hiPSC-Derived Microglia in Human Brain Development in Health and Disease","funder_award_id":"R01NS123642","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G909366919","display_name":null,"funder_award_id":"ECCS-2025752","funder_id":"https://openalex.org/F4320332603","funder_display_name":"University of California, San Diego"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320306171","display_name":"California Institute for Regenerative Medicine","ror":"https://ror.org/033m8b439"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332163","display_name":"U.S. Food and Drug Administration","ror":"https://ror.org/034xvzb47"},{"id":"https://openalex.org/F4320332603","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337361","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63"},{"id":"https://openalex.org/F4320337392","display_name":"Division of Electrical, Communications and Cyber Systems","ror":"https://ror.org/01krpsy48"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410544690.pdf","grobid_xml":"https://content.openalex.org/works/W4410544690.grobid-xml"},"referenced_works_count":112,"referenced_works":["https://openalex.org/W1502247841","https://openalex.org/W1553983967","https://openalex.org/W1810028515","https://openalex.org/W1904057448","https://openalex.org/W1963981940","https://openalex.org/W1967976720","https://openalex.org/W1972718751","https://openalex.org/W1976553601","https://openalex.org/W1984417662","https://openalex.org/W1985300622","https://openalex.org/W1986214383","https://openalex.org/W1991190655","https://openalex.org/W1994112912","https://openalex.org/W1994341055","https://openalex.org/W1996810324","https://openalex.org/W2002786273","https://openalex.org/W2005457526","https://openalex.org/W2022636540","https://openalex.org/W2035618305","https://openalex.org/W2036349588","https://openalex.org/W2036505824","https://openalex.org/W2040062620","https://openalex.org/W2047305537","https://openalex.org/W2048914346","https://openalex.org/W2050081851","https://openalex.org/W2056036909","https://openalex.org/W2059743066","https://openalex.org/W2063511140","https://openalex.org/W2065602929","https://openalex.org/W2070268956","https://openalex.org/W2070521037","https://openalex.org/W2080045669","https://openalex.org/W2083599207","https://openalex.org/W2088745158","https://openalex.org/W2100268171","https://openalex.org/W2105958725","https://openalex.org/W2114562156","https://openalex.org/W2121238039","https://openalex.org/W2129013826","https://openalex.org/W2134208433","https://openalex.org/W2137526110","https://openalex.org/W2146512944","https://openalex.org/W2147815618","https://openalex.org/W2152395503","https://openalex.org/W2169086666","https://openalex.org/W2169353806","https://openalex.org/W2197124664","https://openalex.org/W2213423782","https://openalex.org/W2280539066","https://openalex.org/W2321544337","https://openalex.org/W2323326409","https://openalex.org/W2340773711","https://openalex.org/W2609844460","https://openalex.org/W2743970262","https://openalex.org/W2751958484","https://openalex.org/W2769624840","https://openalex.org/W2783909286","https://openalex.org/W2790144556","https://openalex.org/W2794616878","https://openalex.org/W2801956060","https://openalex.org/W2804327040","https://openalex.org/W2883677209","https://openalex.org/W2893194701","https://openalex.org/W2897829040","https://openalex.org/W2908678941","https://openalex.org/W2935011067","https://openalex.org/W2945042211","https://openalex.org/W2945401607","https://openalex.org/W2945485466","https://openalex.org/W2952835325","https://openalex.org/W2959722029","https://openalex.org/W2970454553","https://openalex.org/W2994116424","https://openalex.org/W3006527673","https://openalex.org/W3013247908","https://openalex.org/W3025006661","https://openalex.org/W3043898043","https://openalex.org/W3048156353","https://openalex.org/W3093075182","https://openalex.org/W3157757218","https://openalex.org/W3165194952","https://openalex.org/W3171124321","https://openalex.org/W3174840501","https://openalex.org/W3175752499","https://openalex.org/W3187995495","https://openalex.org/W3190999458","https://openalex.org/W3193351020","https://openalex.org/W3195100019","https://openalex.org/W3198684761","https://openalex.org/W3207429165","https://openalex.org/W3217412351","https://openalex.org/W4200319729","https://openalex.org/W4200529260","https://openalex.org/W4220813465","https://openalex.org/W4225278364","https://openalex.org/W4229003364","https://openalex.org/W4242289937","https://openalex.org/W4283724143","https://openalex.org/W4289521547","https://openalex.org/W4292116816","https://openalex.org/W4296078644","https://openalex.org/W4309775970","https://openalex.org/W4365142160","https://openalex.org/W4376615135","https://openalex.org/W4383872379","https://openalex.org/W4387841951","https://openalex.org/W4391784814","https://openalex.org/W4391842138","https://openalex.org/W4396610031","https://openalex.org/W4399546757","https://openalex.org/W6797786779","https://openalex.org/W6846909007"],"related_works":["https://openalex.org/W4405525659","https://openalex.org/W4402134920","https://openalex.org/W1987851465","https://openalex.org/W2804327040","https://openalex.org/W2786666880","https://openalex.org/W2070042441","https://openalex.org/W4311503098","https://openalex.org/W2805213681","https://openalex.org/W2613982597","https://openalex.org/W2914456460"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-05-21T00:00:00"}