{"id":"https://openalex.org/W4410280464","doi":"https://doi.org/10.1111/ijd.17841","title":"Clinical Outcomes and Prognosis in Atypical Fibroxanthoma: A Systematic Review and Meta\u2010Analysis","display_name":"Clinical Outcomes and Prognosis in Atypical Fibroxanthoma: A Systematic Review and Meta\u2010Analysis","publication_year":2025,"publication_date":"2025-05-11","ids":{"openalex":"https://openalex.org/W4410280464","doi":"https://doi.org/10.1111/ijd.17841","pmid":"https://pubmed.ncbi.nlm.nih.gov/40350546"},"language":"en","primary_location":{"id":"doi:10.1111/ijd.17841","doi":"https://doi.org/10.1111/ijd.17841","is_oa":true,"landing_page_url":"https://doi.org/10.1111/ijd.17841","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijd.17841","source":{"id":"https://openalex.org/S32635664","display_name":"International Journal of Dermatology","issn_l":"0011-9059","issn":["0011-9059","1365-4362","1365-4632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Dermatology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijd.17841","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107047566","display_name":"Rebecca von Dannecker","orcid":"https://orcid.org/0000-0003-0479-3098","observed_orcids":["https://orcid.org/0000-0003-0479-3098"]},"institutions":[{"id":"https://openalex.org/I151854742","display_name":"Faculdade de Medicina de Mar\u00edlia","ror":"https://ror.org/00pm9hx30","country_code":"BR","type":"education","lineage":["https://openalex.org/I151854742"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Rebecca von Dannecker","raw_affiliation_strings":["Marilia Medical School  S\u00e3o Paulo Brazil"],"raw_orcid":"https://orcid.org/0000-0003-0479-3098","affiliations":[{"raw_affiliation_string":"Marilia Medical School  S\u00e3o Paulo Brazil","institution_ids":["https://openalex.org/I151854742"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034668662","display_name":"Lilia Maria Lima de Oliveira","orcid":"https://orcid.org/0000-0002-5672-2649","observed_orcids":["https://orcid.org/0000-0002-5672-2649","https://orcid.org/0009-0001-8503-8707"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lilia Maria Lima de Oliveira","raw_affiliation_strings":["Harvard T.H Chan School of Public Health, Principles and Practice of Clinical Research (PPCR), ECPE  Boston Massachusetts USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard T.H Chan School of Public Health, Principles and Practice of Clinical Research (PPCR), ECPE  Boston Massachusetts USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092488538","display_name":"Izadora Lapenda","orcid":"https://orcid.org/0000-0003-1972-3922","observed_orcids":["https://orcid.org/0000-0003-1972-3922"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Izadora Lapenda","raw_affiliation_strings":["Pernambuco College of Health  Pernambuco Brazil"],"raw_orcid":"https://orcid.org/0000-0003-1972-3922","affiliations":[{"raw_affiliation_string":"Pernambuco College of Health  Pernambuco Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Luiza Pinto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210166250","display_name":"Universidade de Santo Amaro","ror":"https://ror.org/05nvmzs58","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210166250"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Luiza Pinto","raw_affiliation_strings":["Santo Amaro University  S\u00e3o Paulo Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Santo Amaro University  S\u00e3o Paulo Brazil","institution_ids":["https://openalex.org/I4210166250"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113540964","display_name":"Sarah Soares Amorim","orcid":"https://orcid.org/0009-0004-8815-4596","observed_orcids":["https://orcid.org/0009-0004-8815-4596"]},"institutions":[{"id":"https://openalex.org/I25112270","display_name":"Universidade Federal de Pernambuco","ror":"https://ror.org/047908t24","country_code":"BR","type":"education","lineage":["https://openalex.org/I25112270"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Sarah Soares Amorim","raw_affiliation_strings":["Federal University of Pernambuco  Pernambuco Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Federal University of Pernambuco  Pernambuco Brazil","institution_ids":["https://openalex.org/I25112270"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117511748","display_name":"Eduarda Pandi\u00e1","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eduarda Pandia","raw_affiliation_strings":["Faculty of Medical Sciences of Minas Gerais  Minas Gerais Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Medical Sciences of Minas Gerais  Minas Gerais Brazil","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102043123","display_name":"Michele Kreuz","orcid":"https://orcid.org/0009-0009-8968-8190","observed_orcids":["https://orcid.org/0009-0009-8968-8190"]},"institutions":[{"id":"https://openalex.org/I51882195","display_name":"Universidade Luterana do Brasil","ror":"https://ror.org/00kde4z41","country_code":"BR","type":"education","lineage":["https://openalex.org/I51882195"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Michele Kreuz","raw_affiliation_strings":["Lutheran University of Brazil  Rio Grande do Sul Brazil"],"raw_orcid":"https://orcid.org/0009-0009-8968-8190","affiliations":[{"raw_affiliation_string":"Lutheran University of Brazil  Rio Grande do Sul Brazil","institution_ids":["https://openalex.org/I51882195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117511749","display_name":"Ana Julia Marques Bluhm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I151854742","display_name":"Faculdade de Medicina de Mar\u00edlia","ror":"https://ror.org/00pm9hx30","country_code":"BR","type":"education","lineage":["https://openalex.org/I151854742"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Ana Julia Marques Bluhm","raw_affiliation_strings":["Marilia Medical School  S\u00e3o Paulo Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marilia Medical School  S\u00e3o Paulo Brazil","institution_ids":["https://openalex.org/I151854742"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031914584","display_name":"Matheus de Melo Lobo","orcid":"https://orcid.org/0000-0001-7530-7531","observed_orcids":["https://orcid.org/0000-0001-7530-7531"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I3019035496","display_name":"AC Camargo Hospital","ror":"https://ror.org/03025ga79","country_code":"BR","type":"healthcare","lineage":["https://openalex.org/I3019035496"]}],"countries":["BR","US"],"is_corresponding":false,"raw_author_name":"Matheus de Melo Lobo","raw_affiliation_strings":["Department of Cutaneous Oncology A. C. Camargo Cancer Center  S\u00e3o Paulo Brazil","Harvard T.H Chan School of Public Health, Principles and Practice of Clinical Research (PPCR), ECPE  Boston Massachusetts USA"],"raw_orcid":"https://orcid.org/0000-0001-7530-7531","affiliations":[{"raw_affiliation_string":"Department of Cutaneous Oncology A. C. Camargo Cancer Center  S\u00e3o Paulo Brazil","institution_ids":["https://openalex.org/I3019035496"]},{"raw_affiliation_string":"Harvard T.H Chan School of Public Health, Principles and Practice of Clinical Research (PPCR), ECPE  Boston Massachusetts USA","institution_ids":["https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5107047566"],"corresponding_institution_ids":["https://openalex.org/I151854742"],"apc_list":{"value":4150,"currency":"USD","value_usd":4150},"apc_paid":{"value":4150,"currency":"USD","value_usd":4150},"fwci":0.5524,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.48928427,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"64","issue":"9","first_page":"1592","last_page":"1598"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11306","display_name":"Nonmelanoma Skin Cancer Studies","score":0.9276999831199646,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11991","display_name":"Soft tissue tumor case studies","score":0.052299998700618744,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.009800000116229057,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atypical-fibroxanthoma","display_name":"atypical fibroxanthoma","score":0.9950000047683716},{"id":"https://openalex.org/keywords/local-recurrence","display_name":"local recurrence","score":0.8240000009536743},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.9229999780654907},{"id":"https://openalex.org/keywords/disease-specific-mortality","display_name":"disease-specific mortality","score":0.8849999904632568},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":1.0},{"id":"https://openalex.org/keywords/diagnostic-criteria","display_name":"diagnostic criteria","score":0.8989999890327454},{"id":"https://openalex.org/keywords/head-and-neck-lesions","display_name":"head and neck lesions","score":0.7059999704360962},{"id":"https://openalex.org/keywords/benign-skin-tumors","display_name":"benign skin tumor","score":0.49900001287460327}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9070633053779602},{"id":"https://openalex.org/C2778758220","wikidata":"https://www.wikidata.org/wiki/Q2356302","display_name":"Atypical fibroxanthoma","level":3,"score":0.8120624423027039},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.7325391173362732},{"id":"https://openalex.org/C82605166","wikidata":"https://www.wikidata.org/wiki/Q967190","display_name":"Funnel plot","level":4,"score":0.720142662525177},{"id":"https://openalex.org/C2780439572","wikidata":"https://www.wikidata.org/wiki/Q919364","display_name":"Publication bias","level":3,"score":0.7031622529029846},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.6213432550430298},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.5158811807632446},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.46214091777801514},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.46030381321907043},{"id":"https://openalex.org/C119423318","wikidata":"https://www.wikidata.org/wiki/Q7628405","display_name":"Study heterogeneity","level":3,"score":0.4318389892578125},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.4110240638256073},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4059387445449829},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3878968358039856},{"id":"https://openalex.org/C204232928","wikidata":"https://www.wikidata.org/wiki/Q899285","display_name":"Immunohistochemistry","level":2,"score":0.173488050699234},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009364","descriptor_name":"Neoplasm Recurrence, Local","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012878","descriptor_name":"Skin Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D018219","descriptor_name":"Histiocytoma, Benign Fibrous","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018219","descriptor_name":"Histiocytoma, Benign Fibrous","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D018219","descriptor_name":"Histiocytoma, Benign Fibrous","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/ijd.17841","doi":"https://doi.org/10.1111/ijd.17841","is_oa":true,"landing_page_url":"https://doi.org/10.1111/ijd.17841","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijd.17841","source":{"id":"https://openalex.org/S32635664","display_name":"International Journal of Dermatology","issn_l":"0011-9059","issn":["0011-9059","1365-4362","1365-4632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Dermatology","raw_type":"journal-article"},{"id":"pmid:40350546","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40350546","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of dermatology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/ijd.17841","doi":"https://doi.org/10.1111/ijd.17841","is_oa":true,"landing_page_url":"https://doi.org/10.1111/ijd.17841","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijd.17841","source":{"id":"https://openalex.org/S32635664","display_name":"International Journal of Dermatology","issn_l":"0011-9059","issn":["0011-9059","1365-4362","1365-4632"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Dermatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410280464.pdf","grobid_xml":"https://content.openalex.org/works/W4410280464.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1972014357","https://openalex.org/W1979945131","https://openalex.org/W2037051036","https://openalex.org/W2062654717","https://openalex.org/W2069600508","https://openalex.org/W2074240039","https://openalex.org/W2157823046","https://openalex.org/W2179945681","https://openalex.org/W2741532135","https://openalex.org/W2748856169","https://openalex.org/W2856117242","https://openalex.org/W2916775530","https://openalex.org/W2953436493","https://openalex.org/W4210276124","https://openalex.org/W4211054786","https://openalex.org/W4224060110","https://openalex.org/W4224233267","https://openalex.org/W4229039458","https://openalex.org/W4230711661","https://openalex.org/W4235739337","https://openalex.org/W4308583124","https://openalex.org/W4309512629","https://openalex.org/W4319868829","https://openalex.org/W4386163244","https://openalex.org/W6922072469"],"related_works":["https://openalex.org/W1854608156","https://openalex.org/W2748856169","https://openalex.org/W4319868829","https://openalex.org/W2953436493","https://openalex.org/W2856117242","https://openalex.org/W2179945681","https://openalex.org/W4415113762","https://openalex.org/W2926604566","https://openalex.org/W2015899972","https://openalex.org/W2094499049"],"abstract_inverted_index":{"ABSTRACT":[0],"Atypical":[1],"fibroxanthoma":[2],"(AFX)":[3],"is":[4],"a":[5,12,95],"rare":[6],"dermal":[7],"spindle\u2010cell":[8],"tumor":[9],"characterized":[10],"by":[11],"generally":[13],"benign":[14,195],"clinical":[15,196],"course.":[16],"Despite":[17],"recent":[18],"advances,":[19],"there":[20],"are":[21],"still":[22],"challenges":[23],"regarding":[24],"its":[25,193],"accurate":[26,212],"diagnosis,":[27],"prognostic":[28,45,90],"indicators,":[29],"and":[30,37,47,63,83,89,113,136,142,174],"optimal":[31],"management":[32],"strategies.":[33],"This":[34],"systematic":[35],"review":[36],"meta\u2010analysis":[38],"aims":[39],"to":[40,76,181,210],"evaluate":[41],"recurrence":[42,155,188],"rates,":[43],"identify":[44],"factors,":[46],"provide":[48],"evidence\u2010based":[49],"insights":[50],"for":[51,208],"managing":[52],"AFX.":[53],"We":[54],"systematically":[55],"searched":[56],"the":[57,140,169,201],"PubMed,":[58],"Embase,":[59],"Web":[60],"of":[61,133,203],"Science,":[62],"Cochrane":[64],"databases":[65],"following":[66],"PRISMA":[67],"guidelines":[68],"(PROSPERO:":[69],"CRD42024507089).":[70],"Observational":[71],"studies":[72,117],"published":[73],"from":[74],"2002":[75],"2024":[77],"that":[78],"confirmed":[79],"AFX":[80,209],"through":[81],"histopathology":[82],"immunohistochemistry":[84],"were":[85,92,121,124],"included.":[86],"Recurrence":[87],"rates":[88,189],"factors":[91],"analyzed":[93],"using":[94],"random\u2010effects":[96],"model":[97],"with":[98,129],"inverse\u2010variance":[99],"weighting.":[100],"Sensitivity":[101],"analysis":[102],"assessed":[103],"heterogeneity,":[104],"while":[105,168],"publication":[106],"bias":[107],"was":[108,157,172,177],"evaluated":[109],"via":[110],"funnel":[111],"plots":[112],"Egger's":[114],"test.":[115],"Eight":[116],"involving":[118],"1366":[119],"patients":[120],"analyzed.":[122],"Patients":[123],"predominantly":[125,194],"elderly":[126],"males":[127],"(78.9%),":[128],"an":[130],"average":[131],"age":[132],"76.9":[134],"years,":[135],"lesions":[137],"mostly":[138],"in":[139,150,186,190],"head":[141],"neck":[143],"region":[144],"(89%),":[145],"measuring":[146],"about":[147],"14.9":[148],"mm":[149],"diameter.":[151],"The":[152],"pooled":[153],"local":[154],"rate":[156,171],"4.73%":[158],"[95%":[159],"confidence":[160],"interval":[161],"(CI):":[162],"2.24\u20139.73%;":[163],"I":[164],"2":[165],"=":[166],"62.1%],":[167],"metastasis":[170],"0.59%,":[173],"disease\u2010specific":[175],"mortality":[176],"0%.":[178],"Strict":[179],"adherence":[180],"standardized":[182],"diagnostic":[183,206],"criteria":[184],"results":[185],"low":[187],"AFX,":[191],"reinforcing":[192],"behavior.":[197],"Therefore,":[198],"we":[199],"highlight":[200],"importance":[202],"maintaining":[204],"strict":[205],"standards":[207],"ensure":[211],"patient":[213],"prognosis.":[214]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-05-12T00:00:00"}