{"id":"https://openalex.org/W4410159205","doi":"https://doi.org/10.1016/s0168-8278(25)00503-3","title":"THU-489 Disruption of receptor-interacting protein kinase 1 post-translational modifications in alcohol-associated liver disease","display_name":"THU-489 Disruption of receptor-interacting protein kinase 1 post-translational modifications in alcohol-associated liver disease","publication_year":2025,"publication_date":"2025-05-01","ids":{"openalex":"https://openalex.org/W4410159205","doi":"https://doi.org/10.1016/s0168-8278(25)00503-3"},"language":"en","primary_location":{"id":"doi:10.1016/s0168-8278(25)00503-3","doi":"https://doi.org/10.1016/s0168-8278(25)00503-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-8278(25)00503-3","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001507777","display_name":"Uttam Ojha","orcid":"https://orcid.org/0000-0002-2938-5595","observed_orcids":["https://orcid.org/0000-0002-2938-5595"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Uttam Ojha","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001828777","display_name":"Megan R. McMullen","orcid":"https://orcid.org/0009-0007-6020-7125","observed_orcids":["https://orcid.org/0009-0007-6020-7125"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Megan McMullen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009375094","display_name":"Vai Pathak","orcid":"https://orcid.org/0000-0002-3456-7262","observed_orcids":["https://orcid.org/0000-0002-3456-7262"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Vai Pathak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029354918","display_name":"Adam Kim","orcid":"https://orcid.org/0000-0002-3186-3912","observed_orcids":["https://orcid.org/0000-0002-3186-3912"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Adam Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064332538","display_name":"Daniel Miller Rotroff","orcid":"https://orcid.org/0000-0003-0553-3220","observed_orcids":["https://orcid.org/0000-0003-0553-3220","https://orcid.org/0000-0001-6031-9927"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel Rotroff","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006533887","display_name":"Srinivasan Dasarathy","orcid":"https://orcid.org/0000-0003-1774-0104","observed_orcids":["https://orcid.org/0000-0003-1774-0104"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Srinivasan Dasarathy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054624384","display_name":"Jaividhya Dasarathy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jaividhya Dasarathy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049178112","display_name":"David W. Streem","orcid":"https://orcid.org/0000-0001-5804-7598","observed_orcids":["https://orcid.org/0000-0001-5804-7598"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David Streem","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066625440","display_name":"Nicole Welch","orcid":"https://orcid.org/0000-0002-4655-5146","observed_orcids":["https://orcid.org/0000-0002-4655-5146"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nicole Welch","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5018975447","display_name":"Laura E. Nagy","orcid":"https://orcid.org/0000-0002-0580-2809","observed_orcids":["https://orcid.org/0000-0002-0580-2809"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laura Nagy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"82","issue":null,"first_page":"S111","last_page":"S111"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11207","display_name":"Alcohol Consumption and Health Effects","score":0.9810000061988831,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.004999999888241291,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10999","display_name":"Organ Transplantation Techniques and Outcomes","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ripk1","display_name":"RIPK1","score":0.9470000267028809},{"id":"https://openalex.org/keywords/post-translational-modification","display_name":"post-translational modification","score":0.9739999771118164},{"id":"https://openalex.org/keywords/alcoholic-liver-disease","display_name":"alcoholic liver disease","score":0.9810000061988831},{"id":"https://openalex.org/keywords/alcoholic-liver-injury","display_name":"alcoholic liver injury","score":0.777999997138977}],"concepts":[{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.5309405326843262},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.5085798501968384},{"id":"https://openalex.org/C100631289","wikidata":"https://www.wikidata.org/wiki/Q898362","display_name":"Posttranslational modification","level":3,"score":0.4851137399673462},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3928271532058716},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3722281754016876},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.227691650390625},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.10388696193695068}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0168-8278(25)00503-3","doi":"https://doi.org/10.1016/s0168-8278(25)00503-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0168-8278(25)00503-3","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9391000270843506,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2613964447","https://openalex.org/W4399462041","https://openalex.org/W7162535971","https://openalex.org/W4410138891","https://openalex.org/W4399461339","https://openalex.org/W1041158958","https://openalex.org/W7162552082","https://openalex.org/W7146568474","https://openalex.org/W4410174975","https://openalex.org/W4235827767"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-05-08T00:00:00"}