{"id":"https://openalex.org/W4410109286","doi":"https://doi.org/10.1016/j.bone.2025.117516","title":"Metabolic, skeletal, and cartilage effects of a high-fat diet and the therapeutic impact of MGL3196 are age- and sex-dependent in mice","display_name":"Metabolic, skeletal, and cartilage effects of a high-fat diet and the therapeutic impact of MGL3196 are age- and sex-dependent in mice","publication_year":2025,"publication_date":"2025-05-06","ids":{"openalex":"https://openalex.org/W4410109286","doi":"https://doi.org/10.1016/j.bone.2025.117516","pmid":"https://pubmed.ncbi.nlm.nih.gov/40339773","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12150794"},"language":"en","primary_location":{"id":"doi:10.1016/j.bone.2025.117516","doi":"https://doi.org/10.1016/j.bone.2025.117516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bone.2025.117516","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bone","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.bone.2025.117516","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"O. Perez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I26347476","display_name":"Loma Linda University","ror":"https://ror.org/04bj28v14","country_code":"US","type":"education","lineage":["https://openalex.org/I26347476"]},{"id":"https://openalex.org/I4210095401","display_name":"Loma Linda University Health Care","ror":"https://ror.org/00saxze38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210095401"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"O. Perez","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America; Departments of Medicine, Loma Linda University, Loma Linda, CA 92354, United States of America. Electronic address: Oasis.Perez@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America; Departments of Medicine, Loma Linda University, Loma Linda, CA 92354, United States of America. Electronic address: Oasis.Perez@va.gov","institution_ids":["https://openalex.org/I26347476","https://openalex.org/I4210095401","https://openalex.org/I4210141570"]}]},{"author_position":"middle","author":{"id":null,"display_name":"G.A. Gomez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G.A. Gomez","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: gustavo.gomez2@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: gustavo.gomez2@va.gov","institution_ids":["https://openalex.org/I4210116750","https://openalex.org/I4210141570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021950759","display_name":"Chandrasekhar Kesavan","orcid":"https://orcid.org/0000-0003-0685-0367","observed_orcids":["https://orcid.org/0000-0003-0685-0367"]},"institutions":[{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Kesavan","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: chandrasekhar.kesavan@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: chandrasekhar.kesavan@va.gov","institution_ids":["https://openalex.org/I4210116750","https://openalex.org/I4210141570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012368414","display_name":"Bouchra Edderkaoui","orcid":"https://orcid.org/0000-0002-6407-9411","observed_orcids":["https://orcid.org/0000-0002-6407-9411"]},"institutions":[{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"B. Edderkaoui","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: bouchra.edderkaoui@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: bouchra.edderkaoui@va.gov","institution_ids":["https://openalex.org/I4210116750","https://openalex.org/I4210141570"]}]},{"author_position":"middle","author":{"id":null,"display_name":"A. Muralidharan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Muralidharan","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: aruljothi.muralidharan@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: aruljothi.muralidharan@va.gov","institution_ids":["https://openalex.org/I4210116750","https://openalex.org/I4210141570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084809450","display_name":"Sheila Pourteymoor","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Pourteymoor","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: sheila.pourteymoor@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: sheila.pourteymoor@va.gov","institution_ids":["https://openalex.org/I4210116750","https://openalex.org/I4210141570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048789053","display_name":"Adam Quincey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Quincey","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: quincey@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: quincey@va.gov","institution_ids":["https://openalex.org/I4210141570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079710455","display_name":"V. Franklin Sechriest","orcid":"https://orcid.org/0000-0002-3839-2762","observed_orcids":["https://orcid.org/0000-0002-3839-2762"]},"institutions":[{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"V.F. Sechriest","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: vernon.sechriest@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America. Electronic address: vernon.sechriest@va.gov","institution_ids":["https://openalex.org/I4210116750","https://openalex.org/I4210141570"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054497725","display_name":"Subburaman Mohan","orcid":"https://orcid.org/0000-0003-0063-986X","observed_orcids":["https://orcid.org/0000-0003-0063-986X"]},"institutions":[{"id":"https://openalex.org/I26347476","display_name":"Loma Linda University","ror":"https://ror.org/04bj28v14","country_code":"US","type":"education","lineage":["https://openalex.org/I26347476"]},{"id":"https://openalex.org/I4210095401","display_name":"Loma Linda University Health Care","ror":"https://ror.org/00saxze38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210095401"]},{"id":"https://openalex.org/I4210116750","display_name":"Jerry L. Pettis Memorial VA Medical Center","ror":"https://ror.org/02bqrry13","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210116750","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]},{"id":"https://openalex.org/I4210141570","display_name":"VA Loma Linda Healthcare System","ror":"https://ror.org/03z6z3n38","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210138663","https://openalex.org/I4210141570"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"S. Mohan","raw_affiliation_strings":["Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America; Departments of Medicine, Loma Linda University, Loma Linda, CA 92354, United States of America; Biochemistry, Loma Linda University, Loma Linda, CA 92354, United States of America; Orthopedic Surgery, Loma Linda University, Loma Linda, CA 92354, United States of America. Electronic address: Subburaman.mohan@va.gov"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Musculoskeletal Disease Center, VA Loma Linda Healthcare System, Loma Linda, CA 92357, United States of America; Departments of Medicine, Loma Linda University, Loma Linda, CA 92354, United States of America; Biochemistry, Loma Linda University, Loma Linda, CA 92354, United States of America; Orthopedic Surgery, Loma Linda University, Loma Linda, CA 92354, United States of America. Electronic address: Subburaman.mohan@va.gov","institution_ids":["https://openalex.org/I26347476","https://openalex.org/I4210095401","https://openalex.org/I4210116750","https://openalex.org/I4210141570"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5054497725"],"corresponding_institution_ids":["https://openalex.org/I26347476","https://openalex.org/I4210095401","https://openalex.org/I4210116750","https://openalex.org/I4210141570"],"apc_list":{"value":3960,"currency":"USD","value_usd":3960},"apc_paid":null,"fwci":0.5978,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.59037555,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"198","issue":null,"first_page":"117516","last_page":"117516"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.5327000021934509,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.2524000108242035,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.04569999873638153,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thyroid-hormone-receptor-beta-agonist","display_name":"thyroid hormone receptor beta agonist","score":0.9649999737739563},{"id":"https://openalex.org/keywords/high-fat-diet","display_name":"high-fat diet","score":0.996999979019165},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.753000020980835},{"id":"https://openalex.org/keywords/aging","display_name":"aging","score":0.6480000019073486},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cortical-bone-loss","display_name":"cortical bone loss","score":0.796999990940094},{"id":"https://openalex.org/keywords/trabecular-bone-loss","display_name":"trabecular bone loss","score":0.9829999804496765},{"id":"https://openalex.org/keywords/articular-cartilage-degeneration","display_name":"articular cartilage degeneration","score":0.8109999895095825},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.8109999895095825},{"id":"https://openalex.org/keywords/wnt16","display_name":"WNT16","score":0.7590000033378601},{"id":"https://openalex.org/keywords/sclerostin","display_name":"sclerostin","score":0.9940000176429749},{"id":"https://openalex.org/keywords/bone-formation","display_name":"bone formation","score":0.5559999942779541},{"id":"https://openalex.org/keywords/lipid-metabolism","display_name":"lipid metabolism","score":0.5419999957084656}],"concepts":[{"id":"https://openalex.org/C2780550940","wikidata":"https://www.wikidata.org/wiki/Q502730","display_name":"Cartilage","level":2,"score":0.6550552845001221},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5648918747901917},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5541738271713257},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.48165786266326904},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3797505497932434},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3305100202560425},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.17122259736061096}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001835","descriptor_name":"Body Weight","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D001842","descriptor_name":"Bone and Bones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002356","descriptor_name":"Cartilage","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012727","descriptor_name":"Sex Characteristics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013977","descriptor_name":"Tibia","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013977","descriptor_name":"Tibia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D050154","descriptor_name":"Adiposity","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059305","descriptor_name":"Diet, High-Fat","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.bone.2025.117516","doi":"https://doi.org/10.1016/j.bone.2025.117516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bone.2025.117516","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bone","raw_type":"journal-article"},{"id":"pmid:40339773","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40339773","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12150794","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12150794/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.bone.2025.117516","doi":"https://doi.org/10.1016/j.bone.2025.117516","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bone.2025.117516","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Bone","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/2","score":0.7799999713897705,"display_name":"Zero hunger"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2469022811","display_name":null,"funder_award_id":"I01 BX005263","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G2770579657","display_name":null,"funder_award_id":"IK6 BX005381","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G3462140086","display_name":null,"funder_award_id":"BX005263","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G4383693717","display_name":"Thyroid hormone receptor \u00ce\u00b21 agonist therapy for the treatment of bone marrow adiposity in aging and obesity","funder_award_id":"R21AG062866","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G810201496","display_name":null,"funder_award_id":"BX005381","funder_id":"https://openalex.org/F4320306127","funder_display_name":"U.S. Department of Veterans Affairs"},{"id":"https://openalex.org/G9000868031","display_name":"Role and Mechanism of Action of Ksr2, an Obesity and Type 2 Diabetes Gene, in Bone Metabolism","funder_award_id":"R01AR048139","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320306127","display_name":"U.S. Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W44674334","https://openalex.org/W1540193333","https://openalex.org/W1544458643","https://openalex.org/W1924843228","https://openalex.org/W2006636750","https://openalex.org/W2009845905","https://openalex.org/W2010335941","https://openalex.org/W2012707598","https://openalex.org/W2012868945","https://openalex.org/W2017165492","https://openalex.org/W2018507213","https://openalex.org/W2030624275","https://openalex.org/W2037978897","https://openalex.org/W2047979024","https://openalex.org/W2057792449","https://openalex.org/W2062923543","https://openalex.org/W2075318706","https://openalex.org/W2079010022","https://openalex.org/W2083847239","https://openalex.org/W2089094116","https://openalex.org/W2091042653","https://openalex.org/W2091805259","https://openalex.org/W2098095516","https://openalex.org/W2101676483","https://openalex.org/W2108833696","https://openalex.org/W2128721675","https://openalex.org/W2135301191","https://openalex.org/W2137696823","https://openalex.org/W2145164381","https://openalex.org/W2153101639","https://openalex.org/W2159581380","https://openalex.org/W2168797456","https://openalex.org/W2269839701","https://openalex.org/W2325544658","https://openalex.org/W2337656162","https://openalex.org/W2409416476","https://openalex.org/W2474969214","https://openalex.org/W2595342131","https://openalex.org/W2669395868","https://openalex.org/W2732630371","https://openalex.org/W2789726732","https://openalex.org/W2891227350","https://openalex.org/W2955938362","https://openalex.org/W2985579744","https://openalex.org/W3024083753","https://openalex.org/W3103057680","https://openalex.org/W3177536496","https://openalex.org/W4200547359","https://openalex.org/W4205158849","https://openalex.org/W4224466353","https://openalex.org/W4285395988","https://openalex.org/W4292542165","https://openalex.org/W4294670872","https://openalex.org/W4300905579","https://openalex.org/W4400084792","https://openalex.org/W4402115327"],"related_works":["https://openalex.org/W4400084792","https://openalex.org/W2018507213","https://openalex.org/W4285395988","https://openalex.org/W2979820372","https://openalex.org/W4411856744","https://openalex.org/W3128107096","https://openalex.org/W1508594218","https://openalex.org/W4410974814","https://openalex.org/W2947443734","https://openalex.org/W4403844158"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-05-07T00:00:00"}