{"id":"https://openalex.org/W4410051499","doi":"https://doi.org/10.1007/s13555-025-01430-1","title":"The Impact of Step Therapy on Individuals with Psoriatic Disease in the USA: Patient and Provider Perspectives","display_name":"The Impact of Step Therapy on Individuals with Psoriatic Disease in the USA: Patient and Provider Perspectives","publication_year":2025,"publication_date":"2025-05-02","ids":{"openalex":"https://openalex.org/W4410051499","doi":"https://doi.org/10.1007/s13555-025-01430-1","pmid":"https://pubmed.ncbi.nlm.nih.gov/40317399","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12126447"},"language":"en","primary_location":{"id":"doi:10.1007/s13555-025-01430-1","doi":"https://doi.org/10.1007/s13555-025-01430-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13555-025-01430-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13555-025-01430-1.pdf","source":{"id":"https://openalex.org/S4210222097","display_name":"Dermatology and Therapy","issn_l":"2190-9172","issn":["2190-9172","2193-8210"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatology and Therapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1007/s13555-025-01430-1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114632278","display_name":"Georgia Marquez-Grap","orcid":"https://orcid.org/0000-0002-8342-4954","observed_orcids":["https://orcid.org/0000-0002-8342-4954"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Georgia Marquez-Grap","raw_affiliation_strings":["Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA. Georgia.marquez@ucsf.edu"],"raw_orcid":"https://orcid.org/0000-0002-8342-4954","affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA. Georgia.marquez@ucsf.edu","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085736790","display_name":"Dayna L. Pham","orcid":"https://orcid.org/0009-0000-2077-8213","observed_orcids":["https://orcid.org/0009-0000-2077-8213"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dayna L. Pham","raw_affiliation_strings":["Patient Author, Chicago, IL, USA","Pritzker School of Medicine, University of Chicago, Chicago, IL, USA"],"raw_orcid":"https://orcid.org/0009-0000-2077-8213","affiliations":[{"raw_affiliation_string":"Patient Author, Chicago, IL, USA","institution_ids":[]},{"raw_affiliation_string":"Pritzker School of Medicine, University of Chicago, Chicago, IL, USA","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106410952","display_name":"Andrea Leung","orcid":"https://orcid.org/0009-0007-6165-3071","observed_orcids":["https://orcid.org/0009-0007-6165-3071"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea Leung","raw_affiliation_strings":["Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027645569","display_name":"Melissa C. Leeolou","orcid":"https://orcid.org/0000-0002-9223-2380","observed_orcids":["https://orcid.org/0000-0002-9223-2380"]},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melissa C. Leeolou","raw_affiliation_strings":["Department of Dermatology, Stanford University, Stanford, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Stanford University, Stanford, CA, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078019211","display_name":"Allison C. Kranyak","orcid":"https://orcid.org/0000-0003-0017-138X","observed_orcids":["https://orcid.org/0000-0003-0017-138X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allison Kranyak","raw_affiliation_strings":["Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078581958","display_name":"Wilson J. Liao","orcid":"https://orcid.org/0000-0001-7883-6439","observed_orcids":["https://orcid.org/0000-0001-7883-6439"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wilson Liao","raw_affiliation_strings":["Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, University of California, San Francisco, Room N414, 2340 Sutter Street, San Francisco, CA, 94115, USA","institution_ids":["https://openalex.org/I180670191"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5114632278"],"corresponding_institution_ids":["https://openalex.org/I180670191"],"apc_list":{"value":7400,"currency":"USD","value_usd":7400},"apc_paid":{"value":7400,"currency":"USD","value_usd":7400},"fwci":1.1107,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.74511783,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"15","issue":"7","first_page":"1599","last_page":"1606"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis","score":0.9789999723434448,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11092","display_name":"Spondyloarthritis Studies and Treatments","score":0.011699999682605267,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11792","display_name":"Pharmaceutical Economics and Policy","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/step-therapy","display_name":"step therapy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/psoriatic-disease","display_name":"psoriatic disease","score":0.8429999947547913},{"id":"https://openalex.org/keywords/psoriasis","display_name":"psoriasis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/psoriatic-arthritis","display_name":"psoriatic arthritis","score":1.0},{"id":"https://openalex.org/keywords/biological-therapy","display_name":"biologic therapy","score":0.9279999732971191},{"id":"https://openalex.org/keywords/insurance-denials","display_name":"insurance denials","score":0.7829999923706055},{"id":"https://openalex.org/keywords/patient-perspectives","display_name":"patient perspectives","score":0.4580000042915344},{"id":"https://openalex.org/keywords/provider-perspectives","display_name":"provider perspectives","score":0.968999981880188},{"id":"https://openalex.org/keywords/psychosocial-burden","display_name":"psychosocial burden","score":0.9739999771118164},{"id":"https://openalex.org/keywords/health-care-costs","display_name":"health care costs","score":0.6019999980926514},{"id":"https://openalex.org/keywords/treatment-access","display_name":"treatment access","score":0.3240000009536743}],"concepts":[{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5355889797210693},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.500617265701294},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.36672329902648926},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.09512647986412048}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1007/s13555-025-01430-1","doi":"https://doi.org/10.1007/s13555-025-01430-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13555-025-01430-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13555-025-01430-1.pdf","source":{"id":"https://openalex.org/S4210222097","display_name":"Dermatology and Therapy","issn_l":"2190-9172","issn":["2190-9172","2193-8210"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatology and Therapy","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12126447","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12126447","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatol Ther (Heidelb)","raw_type":"Text"},{"id":"pmid:40317399","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40317399","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatology and therapy","raw_type":"Letter"},{"id":"pmh:oai:doaj.org/article:96acc8ee3eef4be88bac5e23f6a7b262","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/96acc8ee3eef4be88bac5e23f6a7b262","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dermatology and Therapy, Vol 15, Iss 7, Pp 1599-1606 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1007/s13555-025-01430-1","doi":"https://doi.org/10.1007/s13555-025-01430-1","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s13555-025-01430-1","pdf_url":"https://link.springer.com/content/pdf/10.1007/s13555-025-01430-1.pdf","source":{"id":"https://openalex.org/S4210222097","display_name":"Dermatology and Therapy","issn_l":"2190-9172","issn":["2190-9172","2193-8210"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320330","host_organization_name":"Adis, Springer Healthcare","host_organization_lineage":["https://openalex.org/P4310320330","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Adis, Springer Healthcare","Springer Nature"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Dermatology and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410051499.pdf","grobid_xml":"https://content.openalex.org/works/W4410051499.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W181646210","https://openalex.org/W1971301895","https://openalex.org/W1977108269","https://openalex.org/W2080798594","https://openalex.org/W2464736915","https://openalex.org/W2743993411","https://openalex.org/W2790335734","https://openalex.org/W2901986848","https://openalex.org/W2903144156","https://openalex.org/W2912058252","https://openalex.org/W2912335857","https://openalex.org/W2946069606","https://openalex.org/W2956957933","https://openalex.org/W3028355101","https://openalex.org/W3125246404","https://openalex.org/W3153150995","https://openalex.org/W3159598855","https://openalex.org/W3182233600","https://openalex.org/W3198803503","https://openalex.org/W3209723603","https://openalex.org/W4220736806","https://openalex.org/W4220992242","https://openalex.org/W4308862740","https://openalex.org/W4388482807","https://openalex.org/W4390045974","https://openalex.org/W4390973054","https://openalex.org/W4392652385","https://openalex.org/W4400119516"],"related_works":["https://openalex.org/W2971102115","https://openalex.org/W3167623925","https://openalex.org/W2800336929","https://openalex.org/W4391914721","https://openalex.org/W4402104232","https://openalex.org/W7153603659","https://openalex.org/W2937856010","https://openalex.org/W2181422057","https://openalex.org/W3085865154","https://openalex.org/W4253405314"],"abstract_inverted_index":{"The":[0],"management":[1],"of":[2,55,63,144,157,165],"psoriatic":[3,84,110,158],"disease":[4,99],"has":[5,60],"been":[6],"revolutionized":[7],"by":[8,23,78],"biologic":[9,102],"medications":[10],"in":[11,26,33,148],"recent":[12],"years.":[13],"Despite":[14],"their":[15],"efficacy":[16],"and":[17,38,68,72,83,97,112,125,134,168,174],"safety,":[18],"patients":[19,67],"are":[20],"often":[21],"required":[22],"insurance":[24,123],"plans":[25],"the":[27,142,154,163,175],"USA":[28],"or":[29],"national":[30],"formulary":[31],"guidelines":[32],"other":[34,40],"countries":[35],"to":[36,52,105,114],"try":[37],"fail":[39],"treatments":[41],"first,":[42],"which":[43],"is":[44,76,138],"a":[45,61,79,145],"strategy":[46],"called":[47],"step":[48,58,88,126,166],"therapy.":[49,89],"Originally":[50],"designed":[51],"contain":[53],"costs":[54],"specialty":[56],"drugs,":[57],"therapy":[59,127,167],"number":[62],"negative":[64],"impacts":[65,170],"on":[66,171],"providers,":[69,173],"both":[70],"personally":[71],"clinically.":[73],"This":[74,136],"article":[75],"coauthored":[77],"patient":[80],"with":[81,95,101,109],"psoriasis":[82,96],"arthritis":[85,111],"who":[86],"navigated":[87],"She":[90,119],"describes":[91],"her":[92,129],"early":[93],"experiences":[94],"achieving":[98],"control":[100],"medication,":[103],"only":[104],"later":[106],"be":[107],"diagnosed":[108],"need":[113],"revise":[115],"this":[116],"treatment":[117],"plan.":[118],"then":[120,139],"explains":[121],"how":[122],"denials":[124],"impact":[128],"life":[130],"physically,":[131],"emotionally,":[132],"socially,":[133],"medically.":[135],"case":[137],"discussed":[140],"from":[141],"perspective":[143],"dermatologist":[146],"specializing":[147],"inflammatory":[149],"skin":[150],"disease.":[151],"We":[152],"highlight":[153],"psychosocial":[155],"burden":[156,164],"disease,":[159],"as":[160,162],"well":[161],"its":[169],"patients,":[172],"entire":[176],"medical":[177],"system.":[178]},"counts_by_year":[{"year":2026,"cited_by_count":3}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2025-05-03T00:00:00"}