{"id":"https://openalex.org/W4409989303","doi":"https://doi.org/10.1165/rcmb.2024-0332le","title":"A Pilot Study on the Impact of Vaping on Adolescent Lung Function and Nasal Epithelial Gene Expression","display_name":"A Pilot Study on the Impact of Vaping on Adolescent Lung Function and Nasal Epithelial Gene Expression","publication_year":2025,"publication_date":"2025-05-01","ids":{"openalex":"https://openalex.org/W4409989303","doi":"https://doi.org/10.1165/rcmb.2024-0332le","pmid":"https://pubmed.ncbi.nlm.nih.gov/40311078","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12051928"},"language":"en","primary_location":{"id":"doi:10.1165/rcmb.2024-0332le","doi":"https://doi.org/10.1165/rcmb.2024-0332le","is_oa":false,"landing_page_url":"https://doi.org/10.1165/rcmb.2024-0332le","pdf_url":null,"source":{"id":"https://openalex.org/S171155024","display_name":"American Journal of Respiratory Cell and Molecular Biology","issn_l":"1044-1549","issn":["1044-1549","1535-4989"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Respiratory Cell and Molecular Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pubmed.ncbi.nlm.nih.gov/40311078/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079803973","display_name":"Sarah Commodore","orcid":"https://orcid.org/0000-0002-9070-0654","observed_orcids":["https://orcid.org/0000-0002-9070-0654"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Commodore","raw_affiliation_strings":["Indiana University Bloomington, Indiana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University Bloomington, Indiana","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110069580","display_name":"J Hawkins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Hawkins","raw_affiliation_strings":["University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088139753","display_name":"Cheyret Wood","orcid":"https://orcid.org/0000-0002-9418-4917","observed_orcids":["https://orcid.org/0000-0002-9418-4917"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cheyret Wood","raw_affiliation_strings":["University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007274484","display_name":"Cuining Liu","orcid":"https://orcid.org/0000-0003-1079-0045","observed_orcids":["https://orcid.org/0000-0003-1079-0045"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cuining Liu","raw_affiliation_strings":["University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado"],"raw_orcid":"https://orcid.org/0000-0003-1079-0045","affiliations":[{"raw_affiliation_string":"University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017665414","display_name":"Russell Paul Bowler","orcid":"https://orcid.org/0000-0003-4651-363X","observed_orcids":["https://orcid.org/0000-0003-4651-363X"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell P. Bowler","raw_affiliation_strings":["Cleveland Clinic Cleveland, Ohio"],"raw_orcid":"https://orcid.org/0000-0003-4651-363X","affiliations":[{"raw_affiliation_string":"Cleveland Clinic Cleveland, Ohio","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071781603","display_name":"Laura E. Crotty Alexander","orcid":"https://orcid.org/0000-0002-5091-2660","observed_orcids":["https://orcid.org/0000-0002-5091-2660"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Crotty Alexander","raw_affiliation_strings":["University of California, San Diego San Diego, California"],"raw_orcid":"https://orcid.org/0000-0002-5091-2660","affiliations":[{"raw_affiliation_string":"University of California, San Diego San Diego, California","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058359938","display_name":"Peter J. Castaldi","orcid":"https://orcid.org/0000-0001-9920-4713","observed_orcids":["https://orcid.org/0000-0001-9920-4713"]},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Castaldi","raw_affiliation_strings":["Brigham and Women\u2019s Hospital Boston, Massachusetts"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Brigham and Women\u2019s Hospital Boston, Massachusetts","institution_ids":["https://openalex.org/I1283280774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057830517","display_name":"Fernando Holgu\u00edn","orcid":"https://orcid.org/0000-0003-0979-8234","observed_orcids":["https://orcid.org/0000-0003-0979-8234"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fernando Holguin","raw_affiliation_strings":["University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022404035","display_name":"Katerina J. Kechris","orcid":"https://orcid.org/0000-0002-3725-5459","observed_orcids":["https://orcid.org/0000-0002-3725-5459"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katerina Kechris","raw_affiliation_strings":["University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014565144","display_name":"Sunita Sharma","orcid":"https://orcid.org/0000-0001-7179-6059","observed_orcids":["https://orcid.org/0000-0001-7179-6059"]},"institutions":[{"id":"https://openalex.org/I51713134","display_name":"University of Colorado Anschutz","ror":"https://ror.org/03wmf1y16","country_code":"US","type":"education","lineage":["https://openalex.org/I51713134"]},{"id":"https://openalex.org/I921990950","display_name":"University of Colorado Denver","ror":"https://ror.org/02hh7en24","country_code":"US","type":"education","lineage":["https://openalex.org/I921990950"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sunita Sharma","raw_affiliation_strings":["University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado"],"raw_orcid":"https://orcid.org/0000-0001-7179-6059","affiliations":[{"raw_affiliation_string":"University of Colorado\u2013Denver Anschutz Medical Campus Aurora, Colorado","institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5014565144"],"corresponding_institution_ids":["https://openalex.org/I51713134","https://openalex.org/I921990950"],"apc_list":null,"apc_paid":null,"fwci":0.561,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.61397705,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":92,"max":95},"biblio":{"volume":"72","issue":"5","first_page":"594","last_page":"597"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/e-cigarette-use","display_name":"vaping","score":0.9190000295639038},{"id":"https://openalex.org/keywords/e-cigarettes","display_name":"electronic cigarettes","score":0.6420000195503235},{"id":"https://openalex.org/keywords/nasal-epithelium","display_name":"nasal epithelium","score":0.9800000190734863},{"id":"https://openalex.org/keywords/gene-expression","display_name":"gene expression","score":0.984000027179718},{"id":"https://openalex.org/keywords/adolescent-health","display_name":"adolescent health","score":0.45100000500679016}],"concepts":[{"id":"https://openalex.org/C3018587741","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung function","level":3,"score":0.713288426399231},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.6113894581794739},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5626994371414185},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5139848589897156},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.47424760460853577},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.455564022064209},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.4388091564178467},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3591470718383789},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3576427102088928},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.34312933683395386},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27523738145828247},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2159542441368103},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.13065281510353088},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1165/rcmb.2024-0332le","doi":"https://doi.org/10.1165/rcmb.2024-0332le","is_oa":false,"landing_page_url":"https://doi.org/10.1165/rcmb.2024-0332le","pdf_url":null,"source":{"id":"https://openalex.org/S171155024","display_name":"American Journal of Respiratory Cell and Molecular Biology","issn_l":"1044-1549","issn":["1044-1549","1535-4989"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316311","host_organization_name":"American Thoracic Society","host_organization_lineage":["https://openalex.org/P4310316311"],"host_organization_lineage_names":["American Thoracic Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Respiratory Cell and Molecular Biology","raw_type":"journal-article"},{"id":"pmid:40311078","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40311078","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of respiratory cell and molecular biology","raw_type":"Letter"},{"id":"pmh:oai:pubmedcentral.nih.gov:12051928","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40311078/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Respir Cell Mol Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12051928","doi":null,"is_oa":true,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40311078/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Respir Cell Mol Biol","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G526215678","display_name":null,"funder_award_id":"HL R01HL125734","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5349223473","display_name":"MICRORNAS AND EARLY LIFE EXPOSURES IN THE DEVELOPMENTAL ORIGIN OF ASTHMA","funder_award_id":"R01HL125734","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W2005357035","https://openalex.org/W2530203919","https://openalex.org/W2594363119","https://openalex.org/W2759588822","https://openalex.org/W2898598946","https://openalex.org/W2990410265","https://openalex.org/W3162286076","https://openalex.org/W4205588008","https://openalex.org/W4385828697"],"related_works":["https://openalex.org/W4225295990","https://openalex.org/W4237974354","https://openalex.org/W2998921227","https://openalex.org/W3191991411","https://openalex.org/W3041985525","https://openalex.org/W3040992368","https://openalex.org/W3041663334","https://openalex.org/W3087297128","https://openalex.org/W4401132612","https://openalex.org/W4392640138"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-05-02T00:00:00"}