{"id":"https://openalex.org/W4409986166","doi":"https://doi.org/10.7554/elife.100037.3","title":"Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila","display_name":"Fat body-derived cytokine Upd2 controls disciplined migration of tracheal stem cells in Drosophila","publication_year":2025,"publication_date":"2025-04-30","ids":{"openalex":"https://openalex.org/W4409986166","doi":"https://doi.org/10.7554/elife.100037.3"},"language":"en","primary_location":{"id":"doi:10.7554/elife.100037.3","doi":"https://doi.org/10.7554/elife.100037.3","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.100037.3","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.7554/elife.100037.3","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100804937","display_name":"Pengzhen Dong","orcid":"https://orcid.org/0009-0009-7124-695X","observed_orcids":["https://orcid.org/0009-0009-7124-695X"]},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengzhen Dong","raw_affiliation_strings":["Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","State Key Laboratory of Transvascular Implantation Devices"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210158318","https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transvascular Implantation Devices","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100387755","display_name":"Yue Li","orcid":"https://orcid.org/0000-0001-9730-477X","observed_orcids":["https://orcid.org/0000-0001-9730-477X"]},"institutions":[{"id":"https://openalex.org/I4210137217","display_name":"Women's Hospital, School of Medicine, Zhejiang University","ror":"https://ror.org/042t7yh44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210137217"]},{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yue Li","raw_affiliation_strings":["Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","State Key Laboratory of Transvascular Implantation Devices","Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women\u2019s Hospital, Zhejiang University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210158318","https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transvascular Implantation Devices","institution_ids":[]},{"raw_affiliation_string":"Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women\u2019s Hospital, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210137217","https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100411332","display_name":"Yuying Wang","orcid":"https://orcid.org/0000-0002-1837-7557","observed_orcids":["https://orcid.org/0000-0002-1837-7557"]},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuying Wang","raw_affiliation_strings":["Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","State Key Laboratory of Transvascular Implantation Devices"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210158318","https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transvascular Implantation Devices","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000681010","display_name":"Qiang Zhao","orcid":"https://orcid.org/0000-0003-2942-5910","observed_orcids":["https://orcid.org/0000-0003-2942-5910"]},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiang Zhao","raw_affiliation_strings":["Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","State Key Laboratory of Transvascular Implantation Devices"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210158318","https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transvascular Implantation Devices","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111249646","display_name":"Tianfeng Lu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tianfeng Lu","raw_affiliation_strings":["Department of Developmental Biology & Neuroscience, Washington University in St. Louis"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Developmental Biology & Neuroscience, Washington University in St. Louis","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100708293","display_name":"Jian Chen","orcid":"https://orcid.org/0000-0002-3331-5266","observed_orcids":["https://orcid.org/0000-0002-3331-5266"]},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jian Chen","raw_affiliation_strings":["Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","State Key Laboratory of Transvascular Implantation Devices"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210158318","https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transvascular Implantation Devices","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046716542","display_name":"Tianyu Guo","orcid":"https://orcid.org/0000-0001-5703-7064","observed_orcids":["https://orcid.org/0000-0001-5703-7064"]},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Tianyu Guo","raw_affiliation_strings":["Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","State Key Laboratory of Transvascular Implantation Devices"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210158318","https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transvascular Implantation Devices","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021248072","display_name":"Jun Ma","orcid":"https://orcid.org/0000-0002-1609-3294","observed_orcids":["https://orcid.org/0000-0002-1609-3294"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jun Ma","raw_affiliation_strings":["Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine","Institute of Genetics, Zhejiang University International School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genetic Medicine, the Fourth Affiliated Hospital, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I76130692"]},{"raw_affiliation_string":"Institute of Genetics, Zhejiang University International School of Medicine","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057909367","display_name":"Bing Yang","orcid":"https://orcid.org/0000-0002-2293-3384","observed_orcids":["https://orcid.org/0000-0002-2293-3384"]},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bing Yang","raw_affiliation_strings":["MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MOE Laboratory of Biosystem Homeostasis and Protection and Life Sciences Institute, Zhejiang University","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062380697","display_name":"Honggang Wu","orcid":"https://orcid.org/0009-0007-6800-658X","observed_orcids":["https://orcid.org/0009-0007-6800-658X"]},"institutions":[{"id":"https://openalex.org/I4210137217","display_name":"Women's Hospital, School of Medicine, Zhejiang University","ror":"https://ror.org/042t7yh44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210137217"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Honggang Wu","raw_affiliation_strings":["Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women\u2019s Hospital, Zhejiang University School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases, Women\u2019s Hospital, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210137217","https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027764638","display_name":"Hai Huang","orcid":"https://orcid.org/0000-0003-2331-6238","observed_orcids":["https://orcid.org/0000-0003-2331-6238"]},"institutions":[{"id":"https://openalex.org/I4210158318","display_name":"Second Affiliated Hospital of Zhejiang University","ror":"https://ror.org/059cjpv64","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210158318"]},{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hai Huang","raw_affiliation_strings":["Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","State Key Laboratory of Transvascular Implantation Devices","Zhejiang Provincial Key Laboratory of Genetic & Developmental Disorders, Zhejiang University School of Medicine"],"raw_orcid":"https://orcid.org/0000-0003-2331-6238","affiliations":[{"raw_affiliation_string":"Second Affiliated Hospital, and Department of Cell Biology, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I4210158318","https://openalex.org/I76130692"]},{"raw_affiliation_string":"State Key Laboratory of Transvascular Implantation Devices","institution_ids":[]},{"raw_affiliation_string":"Zhejiang Provincial Key Laboratory of Genetic & Developmental Disorders, Zhejiang University School of Medicine","institution_ids":["https://openalex.org/I76130692"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":2500},"apc_paid":{"value":3000,"currency":"USD","value_usd":2500},"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.7085000276565552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.7085000276565552,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.12559999525547028,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.03220000118017197,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fat-body","display_name":"fat body","score":0.6380000114440918},{"id":"https://openalex.org/keywords/jak-stat-signaling","display_name":"JAK/STAT signaling","score":0.859000027179718},{"id":"https://openalex.org/keywords/planar-cell-polarity","display_name":"planar cell polarity","score":0.8980000019073486},{"id":"https://openalex.org/keywords/directional-migration","display_name":"directional migration","score":0.5509999990463257},{"id":"https://openalex.org/keywords/inter-organ-communication","display_name":"inter-organ communication","score":0.871999979019165},{"id":"https://openalex.org/keywords/vesicular-trafficking","display_name":"vesicle trafficking","score":0.7480000257492065},{"id":"https://openalex.org/keywords/rab5","display_name":"Rab5","score":0.8949999809265137},{"id":"https://openalex.org/keywords/rab7","display_name":"Rab7","score":0.996999979019165},{"id":"https://openalex.org/keywords/cytokine-transport","display_name":"cytokine transport","score":0.7649999856948853},{"id":"https://openalex.org/keywords/drosophila-trachea","display_name":"Drosophila trachea","score":0.8090000152587891}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.6117614507675171},{"id":"https://openalex.org/C2776041557","wikidata":"https://www.wikidata.org/wiki/Q3715451","display_name":"Drosophila (subgenus)","level":3,"score":0.5951038002967834},{"id":"https://openalex.org/C2778690821","wikidata":"https://www.wikidata.org/wiki/Q212354","display_name":"Cytokine","level":2,"score":0.5637544393539429},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5132358074188232},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3884216248989105},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.31120729446411133},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1356954574584961},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12863361835479736}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.7554/elife.100037.3","doi":"https://doi.org/10.7554/elife.100037.3","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.100037.3","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.7554/elife.100037.3","doi":"https://doi.org/10.7554/elife.100037.3","is_oa":true,"landing_page_url":"https://doi.org/10.7554/elife.100037.3","pdf_url":null,"source":{"id":"https://openalex.org/S1336409049","display_name":"eLife","issn_l":"2050-084X","issn":["2050-084X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311710","host_organization_name":"eLife Sciences Publications Ltd","host_organization_lineage":["https://openalex.org/P4310311710"],"host_organization_lineage_names":["eLife Sciences Publications Ltd"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"eLife","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2293460267","display_name":null,"funder_award_id":"2023M733098","funder_id":"https://openalex.org/F4320335443","funder_display_name":"Postdoctoral Research Foundation of China"},{"id":"https://openalex.org/G2529192068","display_name":null,"funder_award_id":"NSFC32070784","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3496155969","display_name":null,"funder_award_id":"NSFC32300699","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3555937584","display_name":null,"funder_award_id":"NSFC32000574","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5418785916","display_name":null,"funder_award_id":"LQ24C120001","funder_id":"https://openalex.org/F4320329758","funder_display_name":"Zhejiang Association for Science and Technology"},{"id":"https://openalex.org/G5432701075","display_name":null,"funder_award_id":"2022YFF0608402","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G6152875266","display_name":null,"funder_award_id":"22374128","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6550029015","display_name":null,"funder_award_id":"NSFC92168101","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320329758","display_name":"Zhejiang Association for Science and Technology","ror":"https://ror.org/05mvnz571"},{"id":"https://openalex.org/F4320335443","display_name":"Postdoctoral Research Foundation of China","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F4320336656","display_name":"Thousand Young Talents Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":94,"referenced_works":["https://openalex.org/W106359550","https://openalex.org/W1904063580","https://openalex.org/W1964391716","https://openalex.org/W1965753673","https://openalex.org/W1966102690","https://openalex.org/W1967595340","https://openalex.org/W1967778133","https://openalex.org/W1968137237","https://openalex.org/W1974520977","https://openalex.org/W1975971309","https://openalex.org/W1976043338","https://openalex.org/W1977754435","https://openalex.org/W1982060617","https://openalex.org/W1994668150","https://openalex.org/W1994967651","https://openalex.org/W1998148517","https://openalex.org/W2008127822","https://openalex.org/W2008161604","https://openalex.org/W2010552021","https://openalex.org/W2020459782","https://openalex.org/W2024513653","https://openalex.org/W2027346386","https://openalex.org/W2028088511","https://openalex.org/W2029553949","https://openalex.org/W2030266533","https://openalex.org/W2038363115","https://openalex.org/W2041426549","https://openalex.org/W2044191234","https://openalex.org/W2048112280","https://openalex.org/W2048883725","https://openalex.org/W2057486059","https://openalex.org/W2060114324","https://openalex.org/W2063692341","https://openalex.org/W2065601509","https://openalex.org/W2066354065","https://openalex.org/W2067267062","https://openalex.org/W2074637512","https://openalex.org/W2083602106","https://openalex.org/W2083802827","https://openalex.org/W2083951960","https://openalex.org/W2083971326","https://openalex.org/W2086840459","https://openalex.org/W2090095287","https://openalex.org/W2093746797","https://openalex.org/W2095023470","https://openalex.org/W2096086701","https://openalex.org/W2098259366","https://openalex.org/W2099540110","https://openalex.org/W2105214962","https://openalex.org/W2105277147","https://openalex.org/W2105988430","https://openalex.org/W2106578476","https://openalex.org/W2107563397","https://openalex.org/W2137790111","https://openalex.org/W2144524391","https://openalex.org/W2148070562","https://openalex.org/W2154006198","https://openalex.org/W2163164909","https://openalex.org/W2167948024","https://openalex.org/W2228548648","https://openalex.org/W2238114667","https://openalex.org/W2396836231","https://openalex.org/W2538552363","https://openalex.org/W2569630460","https://openalex.org/W2597024611","https://openalex.org/W2726597581","https://openalex.org/W2730845953","https://openalex.org/W2761893168","https://openalex.org/W2793587459","https://openalex.org/W2895857801","https://openalex.org/W2910730299","https://openalex.org/W2945485301","https://openalex.org/W2966000970","https://openalex.org/W2998973691","https://openalex.org/W3046485479","https://openalex.org/W3090928815","https://openalex.org/W3096016566","https://openalex.org/W3113395967","https://openalex.org/W3127498961","https://openalex.org/W3161066440","https://openalex.org/W3162050238","https://openalex.org/W3195649565","https://openalex.org/W3204231006","https://openalex.org/W3210232381","https://openalex.org/W4280501942","https://openalex.org/W4280640710","https://openalex.org/W4281671315","https://openalex.org/W4283731430","https://openalex.org/W4289836155","https://openalex.org/W4297225312","https://openalex.org/W4318383630","https://openalex.org/W4386935548","https://openalex.org/W4392044409","https://openalex.org/W4394893752"],"related_works":["https://openalex.org/W2023207039","https://openalex.org/W2095247200","https://openalex.org/W2138637254","https://openalex.org/W4280640710","https://openalex.org/W2295112524","https://openalex.org/W2161788184","https://openalex.org/W1991610885","https://openalex.org/W2921419455","https://openalex.org/W2017815214","https://openalex.org/W2167822739"],"abstract_inverted_index":{"Abstract":[0],"Coordinated":[1],"activation":[2,190],"and":[3,87,151,155,187],"directional":[4,97],"migration":[5,51,115,171],"of":[6,49,100,116,127,138,169,172,182,191],"adult":[7,20],"stem":[8,21],"cells":[9,22,60],"are":[10,19],"essential":[11],"for":[12],"maintaining":[13],"tissue":[14],"homeostasis.":[15],"Drosophila":[16],"tracheal":[17,92,117,173],"progenitors":[18,93],"that":[23,34,57,70,121,146,178],"migrate":[24,61],"posteriorly":[25],"along":[26],"the":[27,36,45,74,80,125,167],"dorsal":[28],"trunk":[29],"to":[30,94,135],"replenish":[31],"degenerating":[32],"branches":[33],"disperse":[35],"FGF":[37],"mitogen.":[38],"However,":[39],"it":[40],"is":[41,52,71],"currently":[42],"unknown":[43],"how":[44],"overall":[46],"anterior-to-posterior":[47],"directionality":[48],"such":[50],"controlled.":[53],"Here":[54],"we":[55],"show":[56,120],"individual":[58],"progenitor":[59,141,174],"together":[62],"in":[63,85,91,104,110,130,140,166],"a":[64,68,176],"concerted,":[65],"disciplined":[66,170],"manner,":[67],"behavior":[69],"dependent":[72],"on":[73],"neighboring":[75],"fat":[76,81,105,183],"body.":[77],"We":[78,119,143],"identify":[79],"body-derived":[82,184],"cytokine,":[83],"Upd2,":[84],"targeting":[86],"inducing":[88],"JAK/STAT":[89,108,122,188],"signaling":[90,109,123],"maintain":[95],"their":[96],"migration.":[98],"Perturbation":[99],"either":[101],"Upd2":[102,147,186],"production":[103],"body":[106],"or":[107],"trachea":[111],"causes":[112],"aberrant":[113],"bidirectional":[114],"progenitors.":[118],"promotes":[124],"expression":[126],"genes":[128],"involved":[129],"planar":[131],"cell":[132],"polarity":[133],"leading":[134],"asymmetric":[136],"localization":[137],"Fat":[139],"cells.":[142],"provide":[144],"evidence":[145],"transport":[148],"requires":[149,179],"Rab5-":[150],"Rab7-mediated":[152],"endocytic":[153],"sorting":[154],"Lbm-dependent":[156],"vesicle":[157],"trafficking.":[158],"Our":[159],"study":[160],"thus":[161],"uncovers":[162],"an":[163],"inter-organ":[164],"communication":[165],"control":[168],"cells,":[175],"process":[177],"vesicular":[180],"trafficking":[181],"cytokine":[185],"signaling-mediated":[189],"PCP":[192],"genes.":[193]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-05-01T00:00:00"}