{"id":"https://openalex.org/W4409971587","doi":"https://doi.org/10.5152/turkarchpediatr.2025.24300","title":"Subclinical Enthesitis in Children with Chronic Nonbacterial Osteomyelitis","display_name":"Subclinical Enthesitis in Children with Chronic Nonbacterial Osteomyelitis","publication_year":2025,"publication_date":"2025-04-30","ids":{"openalex":"https://openalex.org/W4409971587","doi":"https://doi.org/10.5152/turkarchpediatr.2025.24300","pmid":"https://pubmed.ncbi.nlm.nih.gov/40353601","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12093391"},"language":"en","primary_location":{"id":"doi:10.5152/turkarchpediatr.2025.24300","doi":"https://doi.org/10.5152/turkarchpediatr.2025.24300","is_oa":true,"landing_page_url":"https://doi.org/10.5152/turkarchpediatr.2025.24300","pdf_url":"https://www.turkarchpediatr.org/index.php/pub/article/download/1674/1673","source":{"id":"https://openalex.org/S4210202510","display_name":"Turkish Archives of Pediatrics","issn_l":"2757-6256","issn":["2757-6256"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","poland-20","russia-white-list-3","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Archives of Pediatrics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.turkarchpediatr.org/index.php/pub/article/download/1674/1673","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Seher Sener","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Seher Sener","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030023020","display_name":"Adalet El\u00e7in Y\u0131ld\u0131z","orcid":"https://orcid.org/0000-0001-7208-8097","observed_orcids":["https://orcid.org/0000-0001-7208-8097"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Adalet Elcin Yildiz","raw_affiliation_strings":["Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091194661","display_name":"Ezgi Deniz Batu","orcid":"https://orcid.org/0000-0003-1065-2363","observed_orcids":["https://orcid.org/0000-0003-1065-2363"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ezgi Deniz Batu","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088374444","display_name":"Erdal Atalay","orcid":"https://orcid.org/0000-0002-8974-7121","observed_orcids":["https://orcid.org/0000-0002-8974-7121"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Erdal Atalay","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058198905","display_name":"\u00d6zge Ba\u015faran","orcid":"https://orcid.org/0000-0002-8534-0930","observed_orcids":["https://orcid.org/0000-0002-8534-0930"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Ozge Basaran","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014633647","display_name":"Yelda Bilginer","orcid":"https://orcid.org/0000-0002-6232-0072","observed_orcids":["https://orcid.org/0000-0002-6232-0072"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Yelda Bilginer","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111220371","display_name":"Seza Ozen","orcid":"https://orcid.org/0000-0003-2883-7868","observed_orcids":["https://orcid.org/0000-0003-2883-7868"]},"institutions":[{"id":"https://openalex.org/I66514158","display_name":"Hacettepe University","ror":"https://ror.org/04kwvgz42","country_code":"TR","type":"education","lineage":["https://openalex.org/I66514158"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Seza Ozen","raw_affiliation_strings":["Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, T\u00fcrkiye","institution_ids":["https://openalex.org/I66514158"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111220371"],"corresponding_institution_ids":["https://openalex.org/I66514158"],"apc_list":null,"apc_paid":null,"fwci":2.9195,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.9012209,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"60","issue":"3","first_page":"289","last_page":"293"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research","score":0.6298999786376953,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research","score":0.6298999786376953,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11092","display_name":"Spondyloarthritis Studies and Treatments","score":0.3521000146865845,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-non-bacterial-osteomyelitis","display_name":"chronic nonbacterial osteomyelitis","score":0.9380000233650208},{"id":"https://openalex.org/keywords/subclinical-enthesitis","display_name":"subclinical enthesitis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/enthesitis-related-arthritis","display_name":"enthesitis-related arthritis","score":0.8349999785423279},{"id":"https://openalex.org/keywords/ultrasonography","display_name":"ultrasonography","score":0.7239999771118164},{"id":"https://openalex.org/keywords/sacroiliitis","display_name":"sacroiliitis","score":0.8190000057220459},{"id":"https://openalex.org/keywords/hla-b27","display_name":"HLA-B27","score":0.9860000014305115},{"id":"https://openalex.org/keywords/disease-flares","display_name":"disease flares","score":0.8980000019073486},{"id":"https://openalex.org/keywords/etanercept","display_name":"etanercept","score":0.8709999918937683},{"id":"https://openalex.org/keywords/methotrexate","display_name":"methotrexate","score":0.9309999942779541}],"concepts":[{"id":"https://openalex.org/C113280763","wikidata":"https://www.wikidata.org/wiki/Q2326546","display_name":"Subclinical infection","level":2,"score":0.913542628288269},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6553155183792114},{"id":"https://openalex.org/C2780131103","wikidata":"https://www.wikidata.org/wiki/Q3055079","display_name":"Enthesitis","level":4,"score":0.6339318156242371},{"id":"https://openalex.org/C2780551157","wikidata":"https://www.wikidata.org/wiki/Q938983","display_name":"Osteomyelitis","level":2,"score":0.5410853624343872},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.5105112791061401},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2439078986644745},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1930902898311615},{"id":"https://openalex.org/C2780564577","wikidata":"https://www.wikidata.org/wiki/Q179945","display_name":"Psoriasis","level":2,"score":0.04425331950187683},{"id":"https://openalex.org/C2776260265","wikidata":"https://www.wikidata.org/wiki/Q511097","display_name":"Psoriatic arthritis","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.5152/turkarchpediatr.2025.24300","doi":"https://doi.org/10.5152/turkarchpediatr.2025.24300","is_oa":true,"landing_page_url":"https://doi.org/10.5152/turkarchpediatr.2025.24300","pdf_url":"https://www.turkarchpediatr.org/index.php/pub/article/download/1674/1673","source":{"id":"https://openalex.org/S4210202510","display_name":"Turkish Archives of Pediatrics","issn_l":"2757-6256","issn":["2757-6256"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","poland-20","russia-white-list-3","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Archives of Pediatrics","raw_type":"journal-article"},{"id":"pmh:oai:oai.turkarchpediatr.org:article/1674","doi":null,"is_oa":true,"landing_page_url":"https://turkarchpediatr.org/index.php/pub/article/view/1674","pdf_url":"https://turkarchpediatr.org/index.php/pub/article/download/1674/1673","source":{"id":"https://openalex.org/S4210202510","display_name":"Turkish Archives of Pediatrics","issn_l":"2757-6256","issn":["2757-6256"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","poland-20","russia-white-list-3","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2757-6256","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12093391","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12093391","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turk Arch Pediatr","raw_type":"Text"},{"id":"pmid:40353601","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40353601","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish archives of pediatrics","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.5152/turkarchpediatr.2025.24300","doi":"https://doi.org/10.5152/turkarchpediatr.2025.24300","is_oa":true,"landing_page_url":"https://doi.org/10.5152/turkarchpediatr.2025.24300","pdf_url":"https://www.turkarchpediatr.org/index.php/pub/article/download/1674/1673","source":{"id":"https://openalex.org/S4210202510","display_name":"Turkish Archives of Pediatrics","issn_l":"2757-6256","issn":["2757-6256"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-d","poland-20","russia-white-list-3","tr-dizin"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Turkish Archives of Pediatrics","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409971587.pdf","grobid_xml":"https://content.openalex.org/works/W4409971587.grobid-xml"},"referenced_works_count":2,"referenced_works":["https://openalex.org/W2221264044","https://openalex.org/W2347192137"],"related_works":["https://openalex.org/W2416633172","https://openalex.org/W1977678397","https://openalex.org/W3213949187","https://openalex.org/W2529523134","https://openalex.org/W4361275339","https://openalex.org/W2965990939","https://openalex.org/W4282588927","https://openalex.org/W4387749196","https://openalex.org/W3092400568","https://openalex.org/W4225286992"],"abstract_inverted_index":{"Objective:":[0],"Enthesitis":[1],"is":[2],"rare":[3],"in":[4,18,31,46,113,142,178,215,230],"chronic":[5],"nonbacterial":[6],"osteomyelitis":[7],"(CNO)":[8],"compared":[9],"to":[10,24,206],"enthesi-":[11],"tis-related":[12],"arthritis.":[13],"It":[14],"may":[15,227],"be":[16,212],"asymptomatic":[17],"CNO":[19,34,43,92,216],"patients.":[20],"This":[21],"study":[22,48],"aimed":[23],"evaluate":[25],"the":[26,68,74,77,83,87,100,143,190],"presence":[27],"of":[28,60,99,153,161,225],"subclinical":[29,171,194],"enthesitis":[30,110,139,162,172,196,210,234],"patients":[32,93,101,115,119,155,217],"with":[33,42,51,192,218],"using":[35],"ultrasonography":[36],"(US).":[37],"Materials":[38],"and":[39,49,71,79,86,105,131,149,181,202,235],"Methods:":[40],"Patients":[41],"were":[44,63,94,107,120,132,177,185],"included":[45],"this":[47],"evaluated":[50],"US":[52,226],"by":[53],"an":[54],"expert":[55],"pediatric":[56],"radiologist.":[57],"The":[58,96,138,223],"entheses":[59],"7":[61],"tendons":[62],"assessed":[64],"bilaterally,":[65],"includ-":[66],"ing":[67],"common":[69],"extensor":[70],"flexor":[72],"tendons,":[73,82],"quadriceps":[75],"tendon,":[76,85],"proximal":[78],"distal":[80],"patellar":[81],"Achilles":[84,195],"plantar":[88,147],"fascia.":[89],"Results:":[90],"Fifty":[91],"included.":[95],"median":[97],"age":[98],"was":[102,111,140,167,173,204],"12.4":[103],"years,":[104],"58%":[106],"female.":[108],"Subclinical":[109,209],"identified":[112],"3":[114,118],"(6%).":[116],"These":[117],"male,":[121],"older":[122],"than":[123],"6":[124],"years":[125],"at":[126,163],"diagnosis,":[127],"had":[128,157,197],"bilateral":[129,150,193],"sacroiliitis,":[130],"positive":[133],"for":[134],"human":[135],"leukocyte":[136],"antigen-B27.":[137],"located":[141],"right":[144,146],"quadriceps,":[145],"fascia,":[148],"Achilles.":[151],"One":[152],"these":[154],"also":[156],"a":[158,198],"clinical":[159,179],"history":[160],"diagnosis.":[164],"Treatment":[165],"modification":[166],"not":[168],"done":[169],"when":[170],"detected":[174],"since":[175],"they":[176],"remission":[180],"acute":[182],"phase":[183],"reactants":[184],"within":[186],"normal":[187],"limits.":[188],"However,":[189],"patient":[191],"disease":[199,237],"flare":[200],"afterward,":[201],"methotrexate":[203],"switched":[205],"etanercept.":[207],"Conclusion:":[208],"can":[211],"observed":[213],"especially":[214],"overlappin-":[219],"genthesitis-related":[220],"arthritis":[221],"features.":[222],"use":[224],"prove":[228],"beneficial":[229],"detecting":[231],"subclini-":[232],"cal":[233],"predicting":[236],"flare.":[238]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2025-05-01T00:00:00"}