{"id":"https://openalex.org/W4409899525","doi":"https://doi.org/10.1016/j.jpain.2025.104811","title":"Sex Differences in Gut Serotonin-Mediated Signaling of Visceral Pain","display_name":"Sex Differences in Gut Serotonin-Mediated Signaling of Visceral Pain","publication_year":2025,"publication_date":"2025-04-01","ids":{"openalex":"https://openalex.org/W4409899525","doi":"https://doi.org/10.1016/j.jpain.2025.104811"},"language":"en","primary_location":{"id":"doi:10.1016/j.jpain.2025.104811","doi":"https://doi.org/10.1016/j.jpain.2025.104811","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpain.2025.104811","pdf_url":null,"source":{"id":"https://openalex.org/S194302669","display_name":"Journal of Pain","issn_l":"1526-5900","issn":["1526-5900","1528-8447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pain","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://doi.org/10.1016/j.jpain.2025.104811","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071821499","display_name":"Sarah A. Najjar","orcid":"https://orcid.org/0000-0003-1959-8658","observed_orcids":["https://orcid.org/0000-0003-1959-8658"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah Najjar","raw_affiliation_strings":["New York University Pain Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Pain Research Center","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031814097","display_name":"Rahi Shah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rahi Shah","raw_affiliation_strings":["New York University Pain Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Pain Research Center","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Michael Quinn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Quinn","raw_affiliation_strings":["New York University Pain Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Pain Research Center","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110918832","display_name":"Daniel Juarez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Juarez","raw_affiliation_strings":["New York University Pain Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Pain Research Center","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016236922","display_name":"Erfaneh Barati","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erfaneh Barati","raw_affiliation_strings":["New York University Pain Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Pain Research Center","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067760423","display_name":"Lin Yung Hung","orcid":"https://orcid.org/0000-0002-5670-3907","observed_orcids":["https://orcid.org/0000-0002-5670-3907"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lin Hung","raw_affiliation_strings":["New York University Pain Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Pain Research Center","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040278204","display_name":"Kara Gross Margolis","orcid":"https://orcid.org/0000-0002-5795-0758","observed_orcids":["https://orcid.org/0000-0002-5795-0758"]},"institutions":[{"id":"https://openalex.org/I4210086933","display_name":"NYU Langone Health","ror":"https://ror.org/005dvqh91","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210086933"]},{"id":"https://openalex.org/I57206974","display_name":"New York University","ror":"https://ror.org/0190ak572","country_code":"US","type":"education","lineage":["https://openalex.org/I57206974"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kara Margolis","raw_affiliation_strings":["New York University Pain Research Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New York University Pain Research Center","institution_ids":["https://openalex.org/I4210086933","https://openalex.org/I57206974"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4180,"currency":"USD","value_usd":4180},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10575019,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":null,"first_page":"104811","last_page":"104811"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.005499999970197678,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/visceral-pain","display_name":"visceral pain","score":0.9300000071525574},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.7990000247955322},{"id":"https://openalex.org/keywords/serotonin-signaling","display_name":"serotonin signaling","score":0.765999972820282},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":0.9319999814033508},{"id":"https://openalex.org/keywords/enterochromaffin-cells","display_name":"enterochromaffin cells","score":0.9919999837875366},{"id":"https://openalex.org/keywords/serotonin-transporter","display_name":"serotonin transporter","score":0.8669999837875366},{"id":"https://openalex.org/keywords/gut-brain-axis","display_name":"gut-brain axis","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.7402253150939941},{"id":"https://openalex.org/C2779794527","wikidata":"https://www.wikidata.org/wiki/Q4116360","display_name":"Visceral pain","level":4,"score":0.5003914833068848},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4322819709777832},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.33184316754341125},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.31555861234664917},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.11729219555854797},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.1169126033782959}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jpain.2025.104811","doi":"https://doi.org/10.1016/j.jpain.2025.104811","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpain.2025.104811","pdf_url":null,"source":{"id":"https://openalex.org/S194302669","display_name":"Journal of Pain","issn_l":"1526-5900","issn":["1526-5900","1528-8447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pain","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jpain.2025.104811","doi":"https://doi.org/10.1016/j.jpain.2025.104811","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jpain.2025.104811","pdf_url":null,"source":{"id":"https://openalex.org/S194302669","display_name":"Journal of Pain","issn_l":"1526-5900","issn":["1526-5900","1528-8447"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Pain","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4223992891","https://openalex.org/W4353031812","https://openalex.org/W1222819451","https://openalex.org/W2073006000","https://openalex.org/W3172139868","https://openalex.org/W1994781929","https://openalex.org/W2071809025","https://openalex.org/W3017112077","https://openalex.org/W4221015254","https://openalex.org/W3177818296"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-04-29T00:00:00"}