{"id":"https://openalex.org/W4409864280","doi":"https://doi.org/10.1007/s00261-025-04953-5","title":"MRI radiomics prediction modelling for pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a systematic review and meta-analysis","display_name":"MRI radiomics prediction modelling for pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a systematic review and meta-analysis","publication_year":2025,"publication_date":"2025-04-28","ids":{"openalex":"https://openalex.org/W4409864280","doi":"https://doi.org/10.1007/s00261-025-04953-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/40293520","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12568919"},"language":"en","primary_location":{"id":"doi:10.1007/s00261-025-04953-5","doi":"https://doi.org/10.1007/s00261-025-04953-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00261-025-04953-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00261-025-04953-5.pdf","source":{"id":"https://openalex.org/S131800149","display_name":"Abdominal Radiology","issn_l":"2366-0058","issn":["2366-0058","2366-004X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Abdominal Radiology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00261-025-04953-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022188078","display_name":"Jason Rai","orcid":"https://orcid.org/0000-0001-7527-9657","observed_orcids":["https://orcid.org/0000-0001-7527-9657"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Jason Rai","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK. jason.rai@nhs.net","Department of Surgery and Cancer, Imperial College London, London, UK. jason.rai@nhs.net"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK. jason.rai@nhs.net","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Surgery and Cancer, Imperial College London, London, UK. jason.rai@nhs.net","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Dinh V. C. Mai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dinh V. C. Mai","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Surgery and Cancer, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Surgery and Cancer, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029390678","display_name":"Ioanna Drami","orcid":"https://orcid.org/0000-0002-1621-0323","observed_orcids":["https://orcid.org/0000-0002-1621-0323"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ioanna Drami","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Surgery and Cancer, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Surgery and Cancer, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067481074","display_name":"Edward T. Pring","orcid":"https://orcid.org/0000-0002-6142-9762","observed_orcids":["https://orcid.org/0000-0002-6142-9762"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Edward T. Pring","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Surgery and Cancer, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Surgery and Cancer, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050148077","display_name":"Laura E. Gould","orcid":"https://orcid.org/0000-0001-8014-3762","observed_orcids":["https://orcid.org/0000-0001-8014-3762"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Laura E. Gould","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Surgery and Cancer, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Surgery and Cancer, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015532047","display_name":"Phillip F. C. Lung","orcid":"https://orcid.org/0000-0002-7459-2323","observed_orcids":["https://orcid.org/0000-0002-7459-2323"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Phillip F. C. Lung","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Radiology, St Mark's the National Bowel Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Radiology, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020586414","display_name":"Thomas Edward Glover","orcid":"https://orcid.org/0000-0002-0923-3842","observed_orcids":["https://orcid.org/0000-0002-0923-3842"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Thomas Glover","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Radiology, St Mark's the National Bowel Hospital, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Radiology, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040891058","display_name":"Joshua David Shur","orcid":"https://orcid.org/0000-0002-4569-4785","observed_orcids":["https://orcid.org/0000-0002-4569-4785"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I4210121186","display_name":"Royal Marsden Hospital","ror":"https://ror.org/034vb5t35","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038","https://openalex.org/I4210121186"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Joshua D. Shur","raw_affiliation_strings":["Department of Radiology, The Royal Marsden NHS Foundation Trust, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Royal Marsden NHS Foundation Trust, London, UK","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I4210121186"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014958681","display_name":"Brandon J. Whitcher","orcid":"https://orcid.org/0000-0002-6452-2399","observed_orcids":["https://orcid.org/0000-0002-6452-2399"]},"institutions":[{"id":"https://openalex.org/I1325846038","display_name":"Royal Marsden NHS Foundation Trust","ror":"https://ror.org/0008wzh48","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038"]},{"id":"https://openalex.org/I4210121186","display_name":"Royal Marsden Hospital","ror":"https://ror.org/034vb5t35","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1325846038","https://openalex.org/I4210121186"]},{"id":"https://openalex.org/I94951947","display_name":"University of Westminster","ror":"https://ror.org/04ycpbx82","country_code":"GB","type":"education","lineage":["https://openalex.org/I94951947"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Brandon Whitcher","raw_affiliation_strings":["Department of Radiology, The Royal Marsden NHS Foundation Trust, London, UK","Research Centre for Optimal Health, University of Westminster, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The Royal Marsden NHS Foundation Trust, London, UK","institution_ids":["https://openalex.org/I1325846038","https://openalex.org/I4210121186"]},{"raw_affiliation_string":"Research Centre for Optimal Health, University of Westminster, London, UK","institution_ids":["https://openalex.org/I94951947"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044513022","display_name":"Thanos Athanasiou","orcid":"https://orcid.org/0000-0002-2525-5515","observed_orcids":["https://orcid.org/0000-0002-2525-5515"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Thanos Athanasiou","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Surgery and Cancer, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Surgery and Cancer, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040361377","display_name":"John T. Jenkins","orcid":"https://orcid.org/0000-0001-8723-9409","observed_orcids":["https://orcid.org/0000-0001-8723-9409"]},"institutions":[{"id":"https://openalex.org/I4210161740","display_name":"St Mark's Hospital","ror":"https://ror.org/05am5g719","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800484787","https://openalex.org/I4210161740"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"John T. Jenkins","raw_affiliation_strings":["BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","Department of Surgery and Cancer, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BiCyCLE Research Group, St Mark's the National Bowel Hospital, London, UK","institution_ids":["https://openalex.org/I4210161740"]},{"raw_affiliation_string":"Department of Surgery and Cancer, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5022188078"],"corresponding_institution_ids":["https://openalex.org/I4210161740","https://openalex.org/I47508984"],"apc_list":{"value":4790,"currency":"USD","value_usd":4790},"apc_paid":{"value":4790,"currency":"USD","value_usd":4790},"fwci":2.7349,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.93561532,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"50","issue":"11","first_page":"5103","last_page":"5123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mri-based-radiomics","display_name":"MRI radiomics","score":0.8330000042915344},{"id":"https://openalex.org/keywords/pathological-complete-response","display_name":"pathological complete response","score":0.9210000038146973},{"id":"https://openalex.org/keywords/locally-advanced-rectal-cancer","display_name":"locally advanced rectal cancer","score":0.9309999942779541},{"id":"https://openalex.org/keywords/neoadjuvant-chemoradiotherapy","display_name":"neoadjuvant chemoradiotherapy","score":1.0},{"id":"https://openalex.org/keywords/treatment-response-prediction","display_name":"treatment response prediction","score":0.8830000162124634},{"id":"https://openalex.org/keywords/organ-preservation","display_name":"organ preservation","score":0.8550000190734863},{"id":"https://openalex.org/keywords/ethnicity","display_name":"ethnicity","score":0.4440000057220459}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9165657162666321},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.7472991347312927},{"id":"https://openalex.org/C187960798","wikidata":"https://www.wikidata.org/wiki/Q7631152","display_name":"Subgroup analysis","level":3,"score":0.5675122737884521},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5666282176971436},{"id":"https://openalex.org/C2778559731","wikidata":"https://www.wikidata.org/wiki/Q23808793","display_name":"Radiomics","level":2,"score":0.5595041513442993},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.49756696820259094},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.48738008737564087},{"id":"https://openalex.org/C2778292576","wikidata":"https://www.wikidata.org/wiki/Q6991934","display_name":"Neoadjuvant therapy","level":4,"score":0.46018797159194946},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.45783448219299316},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.42208540439605713},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4160693883895874},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.4140806794166565},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.39898693561553955},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2721962332725525},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.25646138191223145},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000097188","descriptor_name":"Radiomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D012004","descriptor_name":"Rectal Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D020360","descriptor_name":"Neoadjuvant Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059248","descriptor_name":"Chemoradiotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1007/s00261-025-04953-5","doi":"https://doi.org/10.1007/s00261-025-04953-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00261-025-04953-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00261-025-04953-5.pdf","source":{"id":"https://openalex.org/S131800149","display_name":"Abdominal Radiology","issn_l":"2366-0058","issn":["2366-0058","2366-004X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Abdominal Radiology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:11375030","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12568919","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12568919/pdf/261_2025_Article_4953.pdf","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:40293520","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40293520","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Abdominal radiology (New York)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12568919","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12568919/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Abdom Radiol (NY)","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s00261-025-04953-5","doi":"https://doi.org/10.1007/s00261-025-04953-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00261-025-04953-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00261-025-04953-5.pdf","source":{"id":"https://openalex.org/S131800149","display_name":"Abdominal Radiology","issn_l":"2366-0058","issn":["2366-0058","2366-004X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Abdominal Radiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9940000176429749,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320014","display_name":"Royal College of Surgeons of England","ror":"https://ror.org/02qrg5a24"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409864280.pdf","grobid_xml":"https://content.openalex.org/works/W4409864280.grobid-xml"},"referenced_works_count":86,"referenced_works":["https://openalex.org/W1509445416","https://openalex.org/W1585172067","https://openalex.org/W1969561516","https://openalex.org/W2028926135","https://openalex.org/W2051518060","https://openalex.org/W2088532421","https://openalex.org/W2102150307","https://openalex.org/W2107638293","https://openalex.org/W2107982027","https://openalex.org/W2125452425","https://openalex.org/W2127890285","https://openalex.org/W2132565869","https://openalex.org/W2144717403","https://openalex.org/W2155492044","https://openalex.org/W2159919969","https://openalex.org/W2207554953","https://openalex.org/W2350997045","https://openalex.org/W2623430466","https://openalex.org/W2760796828","https://openalex.org/W2763355946","https://openalex.org/W2767128594","https://openalex.org/W2793785683","https://openalex.org/W2803006182","https://openalex.org/W2888359388","https://openalex.org/W2912199138","https://openalex.org/W2942648398","https://openalex.org/W2948807949","https://openalex.org/W2954017268","https://openalex.org/W2981662953","https://openalex.org/W2988148323","https://openalex.org/W2989835383","https://openalex.org/W3000149607","https://openalex.org/W3010432693","https://openalex.org/W3013222846","https://openalex.org/W3014994169","https://openalex.org/W3016622556","https://openalex.org/W3033965569","https://openalex.org/W3035210538","https://openalex.org/W3045639672","https://openalex.org/W3081371368","https://openalex.org/W3102582058","https://openalex.org/W3111308000","https://openalex.org/W3125690443","https://openalex.org/W3128646645","https://openalex.org/W3139349917","https://openalex.org/W3153756536","https://openalex.org/W3154995350","https://openalex.org/W3164997807","https://openalex.org/W3166836375","https://openalex.org/W3182633521","https://openalex.org/W3185684129","https://openalex.org/W3186486580","https://openalex.org/W3188793288","https://openalex.org/W3204030525","https://openalex.org/W3204492774","https://openalex.org/W3206452396","https://openalex.org/W3211775721","https://openalex.org/W4200111739","https://openalex.org/W4200568949","https://openalex.org/W4205134630","https://openalex.org/W4206815028","https://openalex.org/W4210889262","https://openalex.org/W4213197528","https://openalex.org/W4223935258","https://openalex.org/W4224274396","https://openalex.org/W4224950174","https://openalex.org/W4244315786","https://openalex.org/W4282981106","https://openalex.org/W4283077878","https://openalex.org/W4283755513","https://openalex.org/W4291190231","https://openalex.org/W4304789115","https://openalex.org/W4307027571","https://openalex.org/W4308688963","https://openalex.org/W4317937009","https://openalex.org/W4318923934","https://openalex.org/W4318950753","https://openalex.org/W4362506779","https://openalex.org/W4364376383","https://openalex.org/W4366742794","https://openalex.org/W4382181533","https://openalex.org/W4383872173","https://openalex.org/W4385994289","https://openalex.org/W4386533765","https://openalex.org/W4388074143","https://openalex.org/W4390268711"],"related_works":["https://openalex.org/W4408272753","https://openalex.org/W4377987076","https://openalex.org/W3210825249","https://openalex.org/W2948807949","https://openalex.org/W7165642653","https://openalex.org/W4223935258","https://openalex.org/W4401572932","https://openalex.org/W2981662953","https://openalex.org/W3211131063","https://openalex.org/W4415851814"],"abstract_inverted_index":{"PURPOSE:":[0],"Predicting":[1],"response":[2,37],"to":[3,20,28,83,235,258],"neoadjuvant":[4],"therapy":[5],"in":[6,33,94,134,155,238,243,262],"locally":[7],"advanced":[8],"rectal":[9],"cancer":[10],"(LARC)":[11],"is":[12,249],"challenging.":[13],"Organ":[14],"preservation":[15,260],"strategies":[16],"can":[17,256],"be":[18,236],"offered":[19],"patients":[21,144],"with":[22],"complete":[23,35],"clinical":[24],"response.":[25],"We":[26,97,138,213],"aim":[27],"evaluate":[29],"MRI-derived":[30],"radiomics":[31,152,232,248],"models":[32],"predicting":[34],"pathological":[36],"(pCR).":[38],"METHODS:":[39],"Search":[40],"included":[41,87],"MEDLINE,":[42],"Embase":[43],"and":[44,52,75],"Cochrane":[45,53],"Central":[46],"Register":[47],"of":[48,55,69,86,229,246],"Controlled":[49],"Trials":[50],"(CENTRAL)":[51],"Database":[54],"Systematic":[56],"Reviews":[57],"(CDSR)":[58],"for":[59,132,145,150,254],"studies":[60,127,141],"published":[61],"before":[62],"1st":[63],"February":[64],"2024.":[65],"The":[66,89,147,227],"Quality":[67,77],"Assessment":[68],"Diagnostic":[70],"Accuracy":[71],"Studies":[72],"2":[73],"(QUADAS-2)":[74],"Radiomics":[76],"Score":[78],"(RQS)":[79],"tools":[80],"were":[81,130],"used":[82],"assess":[84],"quality":[85],"study.":[88],"research":[90,242],"protocol":[91],"was":[92,122,157],"registered":[93],"PROSPERO":[95],"(CRD42024512865).":[96],"calculated":[98],"pooled":[99,148,173,182,195,203],"area":[100],"under":[101],"the":[102,117,135,163,244],"receiver":[103],"operating":[104],"characteristic":[105],"curve":[106],"(AUC)":[107],"using":[108],"a":[109,223],"random-effects":[110],"model.":[111],"To":[112],"compare":[113],"AUC":[114,149,174,183,196,204],"between":[115],"subgroups":[116],"Hanley":[118],"&":[119],"McNeil":[120],"test":[121],"performed.":[123],"RESULTS:":[124],"Forty-four":[125],"eligible":[126],"(12,714":[128],"patients)":[129],"identified":[131],"inclusion":[133],"systematic":[136],"review.":[137],"selected":[139],"thirty-five":[140],"including":[142],"10,543":[143],"meta-analysis.":[146],"MRI":[151,168,219,247],"predicted":[153],"pCR":[154,255],"LARC":[156],"0.87":[158],"(95%":[159,176,185,198,206],"CI":[160,177,186,199,207],"0.84-0.89).":[161],"In":[162],"subgroup":[164],"analysis":[165],"3":[166,217],"T":[167,181,218],"field":[169,220,245],"intensity":[170,221],"had":[171,193],"higher":[172,194],"0.9":[175,197],"0.87-0.94)":[178],"than":[179,201],"1.5":[180],"0.82":[184],"0.80-0.83)":[187],"p":[188,209],"<":[189,210],"0.001.":[190,211],"Asian":[191],"ethnicity":[192,230],"0.87-0.93)":[200],"non-Asian":[202],"0.8":[205],"0.75-0.84)":[208],"CONCLUSION:":[212],"have":[214],"demonstrated":[215],"that":[216],"provides":[222],"superior":[224],"predictive":[225],"performance.":[226],"role":[228],"on":[231],"features":[233],"needs":[234],"explored":[237],"future":[239],"studies.":[240],"Further":[241],"important":[250],"as":[251],"accurate":[252],"prediction":[253],"lead":[257],"organ":[259],"strategy":[261],"LARC.":[263]},"counts_by_year":[{"year":2026,"cited_by_count":17},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2025-04-28T00:00:00"}