{"id":"https://openalex.org/W4409722975","doi":"https://doi.org/10.5327/1516-3180.142s1.11664","title":"Implementa\u00e7\u00e3o da estimativa da incerteza da medi\u00e7\u00e3o utilizando ISO/TS 20914:2019 e CLSI EP15-A3 e defini\u00e7\u00e3o do plano de controle da qualidade com base na M\u00e9trica Sigma: estudo de caso com o marcador tumoral s\u00e9rico CA125","display_name":"Implementa\u00e7\u00e3o da estimativa da incerteza da medi\u00e7\u00e3o utilizando ISO/TS 20914:2019 e CLSI EP15-A3 e defini\u00e7\u00e3o do plano de controle da qualidade com base na M\u00e9trica Sigma: estudo de caso com o marcador tumoral s\u00e9rico CA125","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4409722975","doi":"https://doi.org/10.5327/1516-3180.142s1.11664"},"language":"pt","primary_location":{"id":"doi:10.5327/1516-3180.142s1.11664","doi":"https://doi.org/10.5327/1516-3180.142s1.11664","is_oa":true,"landing_page_url":"https://doi.org/10.5327/1516-3180.142s1.11664","pdf_url":"https://doi.org/10.5327/1516-3180.142s1.11664","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"S\u00e3o Paulo Medical Journal","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.5327/1516-3180.142s1.11664","any_repository_has_fulltext":null},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5074453675","display_name":"Rafael Henriques J\u00e1como","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rafael Henriques J\u00e1como","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068211740","display_name":"Barbara Monteiro Lyra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B\u00e1rbara Monteiro Lyra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017317913","display_name":"Alan Carvalho Dias","orcid":"https://orcid.org/0000-0002-7159-4593","observed_orcids":["https://orcid.org/0000-0002-7159-4593"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alan Carvalho Dias","raw_affiliation_strings":["278 - o andar - S\u00e3o Paulo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"278 - o andar - S\u00e3o Paulo","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074490534","display_name":"Ana Paula de Castro Cantu\u00e1ria","orcid":"https://orcid.org/0000-0001-5828-450X","observed_orcids":["https://orcid.org/0000-0001-5828-450X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ana Paula de Castro Cantu\u00e1ria","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117273885","display_name":"Marcelo Braga Brand\u00e3o Melo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marcelo Braga Brand\u00e3o Melo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Alessandra Lopes Barbosa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alessandra Lopes Barbosa","raw_affiliation_strings":["278 - o andar - S\u00e3o Paulo"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"278 - o andar - S\u00e3o Paulo","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091226799","display_name":"Graciella Ribeiro Martins","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Graciella Ribeiro Martins","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"85","last_page":"86"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control","score":0.9556000232696533,"subfield":{"id":"https://openalex.org/subfields/3607","display_name":"Medical Laboratory Technology"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11890","display_name":"Scientific Measurement and Uncertainty Evaluation","score":0.04179999977350235,"subfield":{"id":"https://openalex.org/subfields/3105","display_name":"Instrumentation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12871","display_name":"Healthcare Quality and Management","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ca125","display_name":"CA125","score":0.9549999833106995},{"id":"https://openalex.org/keywords/measurement-uncertainty","display_name":"measurement uncertainty","score":0.8410000205039978},{"id":"https://openalex.org/keywords/quality-control-plan","display_name":"quality control plan","score":0.7799999713897705},{"id":"https://openalex.org/keywords/sigma-metrics","display_name":"sigma metrics","score":0.7260000109672546},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.6240000128746033},{"id":"https://openalex.org/keywords/tumor-marker-assay","display_name":"tumor marker assay","score":0.6430000066757202},{"id":"https://openalex.org/keywords/expanded-uncertainty","display_name":"expanded uncertainty","score":0.5759999752044678},{"id":"https://openalex.org/keywords/westgard-rules","display_name":"Westgard rules","score":0.7129999995231628},{"id":"https://openalex.org/keywords/analytical-performance","display_name":"analytical performance","score":0.3199999928474426}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8658880591392517}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.5327/1516-3180.142s1.11664","doi":"https://doi.org/10.5327/1516-3180.142s1.11664","is_oa":true,"landing_page_url":"https://doi.org/10.5327/1516-3180.142s1.11664","pdf_url":"https://doi.org/10.5327/1516-3180.142s1.11664","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"S\u00e3o Paulo Medical Journal","raw_type":"proceedings-article"}],"best_oa_location":{"id":"doi:10.5327/1516-3180.142s1.11664","doi":"https://doi.org/10.5327/1516-3180.142s1.11664","is_oa":true,"landing_page_url":"https://doi.org/10.5327/1516-3180.142s1.11664","pdf_url":"https://doi.org/10.5327/1516-3180.142s1.11664","source":null,"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"S\u00e3o Paulo Medical Journal","raw_type":"proceedings-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409722975.pdf","grobid_xml":"https://content.openalex.org/works/W4409722975.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2358711674","https://openalex.org/W2915545170","https://openalex.org/W4409720647","https://openalex.org/W7117343562","https://openalex.org/W2418079209","https://openalex.org/W7125803891","https://openalex.org/W7220224946","https://openalex.org/W4403129283","https://openalex.org/W287904485","https://openalex.org/W4403058730"],"abstract_inverted_index":{"Objetivo:":[0],"O":[1,63,200,205],"CA125":[2,72],"\u00e9":[3],"um":[4,31,163,228],"marcador":[5],"tumoral":[6],"crucial":[7],"na":[8,178],"detec\u00e7\u00e3o":[9],"e":[10,42,60,73,108,113,128,158,177,192,197,210,227,239],"no":[11,83,171],"monitoramento":[12],"do":[13,71,130],"c\u00e2ncer":[14],"de":[15,34,44,77,93,132,143,155,165,174,182,195,219,230,237],"ov\u00e1rio":[16],"epitelial":[17],"invasivo,":[18],"amplamente":[19],"utilizado":[20,36],"para":[21,37,124,151,188,232],"identificar":[22],"carcinoma":[23],"residual":[24],"ou":[25],"recorrente.":[26],"Normalmente,":[27],"os":[28,91,125,189],"fabricantes":[29],"definem":[30],"limite":[32,154],"superior":[33],"refer\u00eancia,":[35],"o":[38,53,58,61,75,88,116,136,141,153,160,217],"in\u00edcio":[39],"da":[40,79,121,138,167,221],"investiga\u00e7\u00e3o":[41],"tomada":[43],"decis\u00e3o":[45],"m\u00e9dica.":[46],"A":[47,185],"incerteza":[48,70,120,147,186],"associada":[49],"aos":[50],"resultados,":[51],"conforme":[52,115],"m\u00e9todo":[54,172],"utilizado,":[55],"pode":[56],"influenciar":[57],"diagn\u00f3stico":[59],"tratamento.":[62],"objetivo":[64],"deste":[65],"estudo":[66],"foi":[67,194,203,208,215],"estimar":[68],"a":[69,110,119,146,224],"definir":[74,152],"plano":[76,164,218],"controle":[78,94,166,220],"qualidade":[80,168],"com":[81,169,211],"base":[82,170,212],"desempenho":[84],"anal\u00edtico.":[85],"M\u00e9todo:":[86],"Para":[87],"estudo,":[89],"utilizaram-se":[90],"materiais":[92],"interno":[95],"PrecciControl":[96],"Tumor":[97],"Marker,":[98],"Roche.":[99],"Foram":[100],"realizadas":[101],"cinco":[102],"r\u00e9plicas":[103],"em":[104],"5":[105],"dias":[106],"consecutivos,":[107],"calculada":[109],"imprecis\u00e3o":[111],"intraensaio":[112],"intralaboratorial,":[114],"EP15-A3.":[117],"Calculou-se":[118],"medi\u00e7\u00e3o":[122],"(MU)":[123],"n\u00edveis":[126,190],"1":[127,191],"2":[129,193],"material":[131],"controle,":[133],"bem":[134],"como":[135],"pooled":[137,201],"MU.":[139],"Utilizou-se":[140],"crit\u00e9rio":[142],"3":[144],"vezes":[145],"padr\u00e3o":[148],"m\u00e1xima":[149],"permitida":[150],"especifica\u00e7\u00e3o":[156],"(13,8%)":[157],"calcular":[159],"Sigma.":[161],"Definiu-se":[162],"MASP":[173],"Vicente":[175],"Falconi":[176],"Estrat\u00e9gia":[179],"6":[180],"Sigma":[181,207],"Westgard.":[183],"Conclus\u00e3o:":[184],"expandida":[187],"3,13":[196],"2,62%,":[198],"respectivamente.":[199],"MU":[202],"2,74%.":[204],"pior":[206],"6,7,":[209],"nesse":[213],"valor":[214],"definido":[216],"qualidade,":[222],"envolvendo":[223],"regra":[225],"1-3s":[226],"ranking":[229],"prioriza\u00e7\u00e3o":[231],"treinamento,":[233],"delta":[234],"check,":[235],"algoritmo":[236],"correla\u00e7\u00e3o":[238],"estat\u00edsticas":[240],"populacionais":[241],"etc.":[242]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-04-24T00:00:00"}