{"id":"https://openalex.org/W4409705675","doi":"https://doi.org/10.1007/s00345-025-05641-1","title":"Pharmacotherapy for BPH-related LUTS: associations between medication patterns, persistence, and treatment failure","display_name":"Pharmacotherapy for BPH-related LUTS: associations between medication patterns, persistence, and treatment failure","publication_year":2025,"publication_date":"2025-04-23","ids":{"openalex":"https://openalex.org/W4409705675","doi":"https://doi.org/10.1007/s00345-025-05641-1","pmid":"https://pubmed.ncbi.nlm.nih.gov/40266351"},"language":"en","primary_location":{"id":"doi:10.1007/s00345-025-05641-1","doi":"https://doi.org/10.1007/s00345-025-05641-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00345-025-05641-1","pdf_url":null,"source":{"id":"https://openalex.org/S49004918","display_name":"World Journal of Urology","issn_l":"0724-4983","issn":["0724-4983","1433-8726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Urology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066002406","display_name":"Takeshi Soda","orcid":"https://orcid.org/0000-0002-9504-1539","observed_orcids":["https://orcid.org/0000-0002-9504-1539"]},"institutions":[{"id":"https://openalex.org/I4210161392","display_name":"Kitano Hospital","ror":"https://ror.org/05rsbck92","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210161392"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takeshi Soda","raw_affiliation_strings":["Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan. ts11885@gmail.com"],"raw_orcid":"https://orcid.org/0000-0002-9504-1539","affiliations":[{"raw_affiliation_string":"Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan. ts11885@gmail.com","institution_ids":["https://openalex.org/I4210161392"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Tomohide Yamauchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161392","display_name":"Kitano Hospital","ror":"https://ror.org/05rsbck92","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210161392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Tomohide Yamauchi","raw_affiliation_strings":["Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan","institution_ids":["https://openalex.org/I4210161392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033495298","display_name":"Hikari Otsuka","orcid":"https://orcid.org/0000-0002-3547-2169","observed_orcids":["https://orcid.org/0000-0002-3547-2169"]},"institutions":[{"id":"https://openalex.org/I4210161392","display_name":"Kitano Hospital","ror":"https://ror.org/05rsbck92","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210161392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hikari Otsuka","raw_affiliation_strings":["Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan","institution_ids":["https://openalex.org/I4210161392"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058508249","display_name":"Noriyuki Makita","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161392","display_name":"Kitano Hospital","ror":"https://ror.org/05rsbck92","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210161392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Noriyuki Makita","raw_affiliation_strings":["Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan","institution_ids":["https://openalex.org/I4210161392"]}]},{"author_position":"last","author":{"id":null,"display_name":"Takuya Okada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161392","display_name":"Kitano Hospital","ror":"https://ror.org/05rsbck92","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210161392"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Takuya Okada","raw_affiliation_strings":["Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Medical Research Institute Kitano Hospital, 2-4-20 Ogimachi, Kita-ku, Osaka, Osaka, 530-8480, Japan","institution_ids":["https://openalex.org/I4210161392"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5066002406"],"corresponding_institution_ids":["https://openalex.org/I4210161392"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":3.1364,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.89603938,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"43","issue":"1","first_page":"245","last_page":"245"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10279","display_name":"Urinary Bladder and Prostate Research","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benign-prostatic-hyperplasia","display_name":"benign prostatic hyperplasia","score":1.0},{"id":"https://openalex.org/keywords/lower-urinary-tract-symptoms","display_name":"lower urinary tract symptoms","score":0.9980000257492065},{"id":"https://openalex.org/keywords/drug-therapy","display_name":"pharmacotherapy","score":0.7699999809265137},{"id":"https://openalex.org/keywords/medication-persistence","display_name":"treatment persistence","score":0.7710000276565552},{"id":"https://openalex.org/keywords/treatment-failure","display_name":"treatment failure","score":0.9089999794960022},{"id":"https://openalex.org/keywords/acute-urinary-retention","display_name":"acute urinary retention","score":0.9570000171661377},{"id":"https://openalex.org/keywords/5alpha-reductase-inhibitors","display_name":"5-alpha reductase inhibitors","score":0.9470000267028809},{"id":"https://openalex.org/keywords/phosphodiesterase-5-inhibitors","display_name":"phosphodiesterase-5 inhibitors","score":0.9879999756813049},{"id":"https://openalex.org/keywords/alpha-blockers","display_name":"alpha-blockers","score":0.8700000047683716},{"id":"https://openalex.org/keywords/antimuscarinic-agents","display_name":"antimuscarinic agents","score":0.9869999885559082},{"id":"https://openalex.org/keywords/beta3-adrenergic-agonists","display_name":"beta3-adrenergic agonists","score":0.9340000152587891},{"id":"https://openalex.org/keywords/prostate-volume","display_name":"prostate volume","score":0.6370000243186951},{"id":"https://openalex.org/keywords/post-void-residual-urine","display_name":"post-void residual urine","score":0.9359999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9000587463378906},{"id":"https://openalex.org/C2781009140","wikidata":"https://www.wikidata.org/wiki/Q7170389","display_name":"Persistence (discontinuity)","level":2,"score":0.7714862823486328},{"id":"https://openalex.org/C500440147","wikidata":"https://www.wikidata.org/wiki/Q701216","display_name":"Pharmacotherapy","level":2,"score":0.7409122586250305},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.6631697416305542},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6257714033126831},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3203452229499817},{"id":"https://openalex.org/C187320778","wikidata":"https://www.wikidata.org/wiki/Q1349130","display_name":"Geotechnical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000317","descriptor_name":"Adrenergic alpha-Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011470","descriptor_name":"Prostatic Hyperplasia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D011470","descriptor_name":"Prostatic Hyperplasia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017211","descriptor_name":"Treatment Failure","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018727","descriptor_name":"Muscarinic Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D058891","descriptor_name":"5-alpha Reductase Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D058986","descriptor_name":"Phosphodiesterase 5 Inhibitors","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D059411","descriptor_name":"Lower Urinary Tract Symptoms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D059411","descriptor_name":"Lower Urinary Tract Symptoms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s00345-025-05641-1","doi":"https://doi.org/10.1007/s00345-025-05641-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00345-025-05641-1","pdf_url":null,"source":{"id":"https://openalex.org/S49004918","display_name":"World Journal of Urology","issn_l":"0724-4983","issn":["0724-4983","1433-8726"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World Journal of Urology","raw_type":"journal-article"},{"id":"pmid:40266351","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40266351","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"World journal of urology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1961129264","https://openalex.org/W1980122321","https://openalex.org/W2005179743","https://openalex.org/W2009604837","https://openalex.org/W2018377518","https://openalex.org/W2081597080","https://openalex.org/W2091348312","https://openalex.org/W2094737423","https://openalex.org/W2108847543","https://openalex.org/W2121759271","https://openalex.org/W2183160060","https://openalex.org/W2430422084","https://openalex.org/W2609434048","https://openalex.org/W2613265109","https://openalex.org/W2985813463","https://openalex.org/W2998444706","https://openalex.org/W3023720856","https://openalex.org/W3086744642","https://openalex.org/W3088050992","https://openalex.org/W3095158159","https://openalex.org/W3128693496","https://openalex.org/W3137039981","https://openalex.org/W3156377477","https://openalex.org/W4384460002","https://openalex.org/W4386725477"],"related_works":["https://openalex.org/W4312141217","https://openalex.org/W2183160060","https://openalex.org/W2139636220","https://openalex.org/W4319826101","https://openalex.org/W2080470371","https://openalex.org/W2051271554","https://openalex.org/W2146012618","https://openalex.org/W2617465977","https://openalex.org/W4411448445","https://openalex.org/W2009604837"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2025-04-24T00:00:00"}