{"id":"https://openalex.org/W4409705000","doi":"https://doi.org/10.15557/pimr.2025.0005","title":"Chrononutrition and the role of melatonin in neonates","display_name":"Chrononutrition and the role of melatonin in neonates","publication_year":2025,"publication_date":"2025-04-18","ids":{"openalex":"https://openalex.org/W4409705000","doi":"https://doi.org/10.15557/pimr.2025.0005"},"language":"en","primary_location":{"id":"doi:10.15557/pimr.2025.0005","doi":"https://doi.org/10.15557/pimr.2025.0005","is_oa":true,"landing_page_url":"https://doi.org/10.15557/pimr.2025.0005","pdf_url":"https://pimr.pl/assets/pdf/artykuly/46-50-paediatrics-family-medicine-1-2025-markowska-ang-pdf.pdf","source":{"id":"https://openalex.org/S2738606534","display_name":"Pediatria i Medycyna Rodzinna","issn_l":"1734-1531","issn":["1734-1531","2391-5021","2451-0742"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310317365","host_organization_name":"Medical Communications Sp. z o.o.","host_organization_lineage":["https://openalex.org/P4310317365"],"host_organization_lineage_names":["Medical Communications Sp. z o.o."],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatria i Medycyna Rodzinna","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://pimr.pl/assets/pdf/artykuly/46-50-paediatrics-family-medicine-1-2025-markowska-ang-pdf.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070144673","display_name":"Magdalena Markowska","orcid":"https://orcid.org/0000-0002-5082-6690","observed_orcids":["https://orcid.org/0000-0002-5082-6690"]},"institutions":[{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Magdalena Markowska","raw_affiliation_strings":["Department of Animal Physiology, Faculty of Biology, University of Warsaw, Warsaw, Poland"],"raw_orcid":"https://orcid.org/0000-0002-5082-6690","affiliations":[{"raw_affiliation_string":"Department of Animal Physiology, Faculty of Biology, University of Warsaw, Warsaw, Poland","institution_ids":["https://openalex.org/I4654613"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5070144673"],"corresponding_institution_ids":["https://openalex.org/I4654613"],"apc_list":null,"apc_paid":null,"fwci":0.3639,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.52599954,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"21","issue":"1","first_page":"46","last_page":"50"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.8568999767303467,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10342","display_name":"Circadian rhythm and melatonin","score":0.8568999767303467,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.12229999899864197,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13289","display_name":"Infant Health and Development","score":0.007199999876320362,"subfield":{"id":"https://openalex.org/subfields/3611","display_name":"Pharmacy"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/melatonin","display_name":"melatonin","score":0.9710000157356262},{"id":"https://openalex.org/keywords/chrononutrition","display_name":"chrononutrition","score":0.9559999704360962},{"id":"https://openalex.org/keywords/newborns","display_name":"neonates","score":0.9559999704360962},{"id":"https://openalex.org/keywords/circadian-rhythm","display_name":"circadian rhythm","score":0.7080000042915344},{"id":"https://openalex.org/keywords/breast-milk","display_name":"breast milk","score":0.7289999723434448},{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.8849999904632568},{"id":"https://openalex.org/keywords/circadian-entrainment","display_name":"circadian entrainment","score":0.9459999799728394},{"id":"https://openalex.org/keywords/sleep-wake-cycle","display_name":"sleep-wake cycle","score":0.8989999890327454},{"id":"https://openalex.org/keywords/brain-development","display_name":"brain development","score":0.7910000085830688},{"id":"https://openalex.org/keywords/immune-maturation","display_name":"immune system maturation","score":0.8149999976158142},{"id":"https://openalex.org/keywords/neonatal-intensive-care","display_name":"neonatal intensive care","score":0.6600000262260437},{"id":"https://openalex.org/keywords/light-exposure","display_name":"light exposure","score":0.6209999918937683},{"id":"https://openalex.org/keywords/feeding-schedule","display_name":"feeding schedule","score":0.5350000262260437},{"id":"https://openalex.org/keywords/diurnal-variation","display_name":"diurnal variation","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9470112323760986},{"id":"https://openalex.org/C2778182776","wikidata":"https://www.wikidata.org/wiki/Q180912","display_name":"Melatonin","level":2,"score":0.8466894626617432},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3798154592514038},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.3333747982978821},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3325698971748352},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2951245903968811}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.15557/pimr.2025.0005","doi":"https://doi.org/10.15557/pimr.2025.0005","is_oa":true,"landing_page_url":"https://doi.org/10.15557/pimr.2025.0005","pdf_url":"https://pimr.pl/assets/pdf/artykuly/46-50-paediatrics-family-medicine-1-2025-markowska-ang-pdf.pdf","source":{"id":"https://openalex.org/S2738606534","display_name":"Pediatria i Medycyna Rodzinna","issn_l":"1734-1531","issn":["1734-1531","2391-5021","2451-0742"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310317365","host_organization_name":"Medical Communications Sp. z o.o.","host_organization_lineage":["https://openalex.org/P4310317365"],"host_organization_lineage_names":["Medical Communications Sp. z o.o."],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatria i Medycyna Rodzinna","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.15557/pimr.2025.0005","doi":"https://doi.org/10.15557/pimr.2025.0005","is_oa":true,"landing_page_url":"https://doi.org/10.15557/pimr.2025.0005","pdf_url":"https://pimr.pl/assets/pdf/artykuly/46-50-paediatrics-family-medicine-1-2025-markowska-ang-pdf.pdf","source":{"id":"https://openalex.org/S2738606534","display_name":"Pediatria i Medycyna Rodzinna","issn_l":"1734-1531","issn":["1734-1531","2391-5021","2451-0742"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310317365","host_organization_name":"Medical Communications Sp. z o.o.","host_organization_lineage":["https://openalex.org/P4310317365"],"host_organization_lineage_names":["Medical Communications Sp. z o.o."],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatria i Medycyna Rodzinna","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"},{"score":0.6875,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409705000.pdf","grobid_xml":"https://content.openalex.org/works/W4409705000.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1948611475","https://openalex.org/W1992320749","https://openalex.org/W2003302378","https://openalex.org/W2007049603","https://openalex.org/W2021257111","https://openalex.org/W2046819164","https://openalex.org/W2059977935","https://openalex.org/W2082272087","https://openalex.org/W2111561559","https://openalex.org/W2114108518","https://openalex.org/W2133283270","https://openalex.org/W2138418546","https://openalex.org/W2921479990","https://openalex.org/W2974782563","https://openalex.org/W2989698988","https://openalex.org/W3047620778","https://openalex.org/W4280574233","https://openalex.org/W4285145862","https://openalex.org/W4318595802","https://openalex.org/W4318612039","https://openalex.org/W4385544546","https://openalex.org/W4396731770","https://openalex.org/W4400921300","https://openalex.org/W4402993901"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"Melatonin":[0],"plays":[1],"a":[2,36,71],"pivotal":[3],"role":[4],"in":[5,61,141,166,189,203],"the":[6,41,44,103,112,158,196],"regulation":[7],"of":[8,43,105,116,128,161],"biological":[9],"rhythms,":[10,130],"beginning":[11],"during":[12],"prenatal":[13],"development":[14],"through":[15],"maternal":[16,32,107],"signalling":[17],"and":[18,50,90,111,124,185,205],"continuing":[19],"postnatally":[20],"via":[21],"breast":[22,118],"milk.":[23],"In":[24],"neonates,":[25],"whose":[26],"circadian":[27,98,109,129,174],"systems":[28],"are":[29,91],"functionally":[30],"immature,":[31],"melatonin":[33,62,88,122,162],"serves":[34],"as":[35,70,137],"critical":[37],"entraining":[38],"agent,":[39],"facilitating":[40],"synchronisation":[42],"sleep\u2013wake":[45],"cycle,":[46],"supporting":[47],"neurodevelopmental":[48,184],"processes,":[49],"enhancing":[51],"immune":[52],"system":[53],"maturation.":[54],"Breast":[55],"milk":[56,178],"demonstrates":[57],"distinct":[58],"diurnal":[59],"variations":[60],"concentration,":[63],"alongside":[64],"other":[65],"bioactive":[66],"components,":[67],"establishing":[68],"it":[69],"vital":[72],"chrononutritional":[73],"medium.":[74],"This":[75,193],"rhythmic":[76],"delivery":[77],"is":[78],"particularly":[79,188],"significant":[80],"for":[81,97],"preterm":[82,191],"infants,":[83],"who":[84],"lack":[85],"sufficient":[86],"endogenous":[87],"production":[89],"especially":[92],"reliant":[93],"on":[94],"exogenous":[95],"sources":[96],"entrainment.":[99],"Several":[100],"factors,":[101],"including":[102,176],"mode":[104],"delivery,":[106],"health,":[108],"alignment,":[110],"handling":[113],"or":[114,146],"processing":[115],"expressed":[117],"milk,":[119],"may":[120,180],"influence":[121],"content":[123],"its":[125],"bioavailability.":[126],"Disruption":[127],"whether":[131],"due":[132],"to":[133,198],"environmental":[134],"factors":[135],"such":[136],"continuous":[138],"light":[139],"exposure":[140],"neonatal":[142,167,206],"intensive":[143],"care":[144],"units":[145],"desynchronised":[147],"feeding":[148,170],"schedules":[149],"\u2013":[150],"can":[151],"interfere":[152],"with":[153,173],"optimal":[154],"physiological":[155],"development.":[156],"Recognising":[157],"chronobiological":[159],"significance":[160],"opens":[163],"new":[164],"perspectives":[165],"care.":[168,208],"Promoting":[169],"practices":[171],"aligned":[172],"principles,":[175],"time-of-day-sensitive":[177],"administration,":[179],"support":[181],"more":[182],"favourable":[183],"immunological":[186],"outcomes,":[187],"vulnerable":[190],"populations.":[192],"knowledge":[194],"has":[195],"potential":[197],"inform":[199],"future":[200],"evidence-based":[201],"strategies":[202],"perinatal":[204],"clinical":[207]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-08-23T07:36:19.812096","created_date":"2025-10-10T00:00:00"}