{"id":"https://openalex.org/W4409557282","doi":"https://doi.org/10.3389/fimmu.2025.1566016","title":"The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy","display_name":"The impact of antibiotic use on outcomes of relapsed/refractory multiple myeloma patients treated with CAR-T therapy","publication_year":2025,"publication_date":"2025-04-17","ids":{"openalex":"https://openalex.org/W4409557282","doi":"https://doi.org/10.3389/fimmu.2025.1566016","pmid":"https://pubmed.ncbi.nlm.nih.gov/40313953","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12043596"},"language":"en","primary_location":{"id":"doi:10.3389/fimmu.2025.1566016","doi":"https://doi.org/10.3389/fimmu.2025.1566016","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2025.1566016","pdf_url":"https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1566016/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1566016/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079871249","display_name":"Lingling Yin","orcid":"https://orcid.org/0000-0002-0922-7135","observed_orcids":["https://orcid.org/0000-0002-0922-7135"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingling Yin","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101613746","display_name":"Bin Lv","orcid":"https://orcid.org/0000-0002-5453-306X","observed_orcids":["https://orcid.org/0000-0002-5453-306X"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bin Lv","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030870483","display_name":"Jiao Ge","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210105400","display_name":"The First People's Hospital of Changzhou","ror":"https://ror.org/01gaj0s81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105400"]},{"id":"https://openalex.org/I4405254887","display_name":"Suzhou University","ror":"https://ror.org/02bz8aa76","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405254887"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiao Ge","raw_affiliation_strings":["Department of Hematology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Suzhou University, Changzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Suzhou University, Changzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210105400","https://openalex.org/I4405254887"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011526018","display_name":"Yuekun Qi","orcid":"https://orcid.org/0000-0003-4431-3060","observed_orcids":["https://orcid.org/0000-0003-4431-3060"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuekun Qi","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051579743","display_name":"Jieyun Xia","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jieyun Xia","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049803938","display_name":"Sha Ma","orcid":"https://orcid.org/0000-0002-0672-6502","observed_orcids":["https://orcid.org/0000-0002-0672-6502"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sha Ma","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110651305","display_name":"Ying Wang","orcid":"https://orcid.org/0000-0002-7607-7202","observed_orcids":["https://orcid.org/0000-0002-7607-7202","https://orcid.org/0009-0009-2862-7036"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Wang","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yang Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yang Liu","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108831751","display_name":"Dian Zhou","orcid":"https://orcid.org/0000-0003-1677-7802","observed_orcids":["https://orcid.org/0000-0003-1677-7802"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dian Zhou","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045094860","display_name":"Jiang Cao","orcid":"https://orcid.org/0000-0003-3767-9283","observed_orcids":["https://orcid.org/0000-0003-3767-9283"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiang Cao","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100551577","display_name":"Zhiling Yan","orcid":"https://orcid.org/0009-0002-0322-431X","observed_orcids":["https://orcid.org/0009-0002-0322-431X"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiling Yan","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073709637","display_name":"Kunming Qi","orcid":"https://orcid.org/0000-0002-0717-9133","observed_orcids":["https://orcid.org/0000-0002-0717-9133"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kunming Qi","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050692462","display_name":"Wei Sang","orcid":"https://orcid.org/0000-0002-1170-7074","observed_orcids":["https://orcid.org/0000-0002-1170-7074","https://orcid.org/0009-0004-2054-1258"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Sang","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101727013","display_name":"Depeng Li","orcid":"https://orcid.org/0000-0001-9650-6249","observed_orcids":["https://orcid.org/0000-0001-9650-6249"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Depeng Li","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113625914","display_name":"Hai Cheng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hai Cheng","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wei Chen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Chen","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100666262","display_name":"Kailin Xu","orcid":"https://orcid.org/0000-0003-1375-1084","observed_orcids":["https://orcid.org/0000-0003-1375-1084"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kailin Xu","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101586828","display_name":"Weiying Gu","orcid":"https://orcid.org/0000-0003-4913-1610","observed_orcids":["https://orcid.org/0000-0003-4913-1610"]},"institutions":[{"id":"https://openalex.org/I4210105400","display_name":"The First People's Hospital of Changzhou","ror":"https://ror.org/01gaj0s81","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105400"]},{"id":"https://openalex.org/I4405254887","display_name":"Suzhou University","ror":"https://ror.org/02bz8aa76","country_code":"CN","type":"education","lineage":["https://openalex.org/I4405254887"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Weiying Gu","raw_affiliation_strings":["Department of Hematology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Suzhou University, Changzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology, The First People's Hospital of Changzhou, The Third Affiliated Hospital of Suzhou University, Changzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210105400","https://openalex.org/I4405254887"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100330758","display_name":"Zhenyu Li","orcid":"https://orcid.org/0000-0003-4610-9135","observed_orcids":["https://orcid.org/0000-0003-4610-9135"]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Zhenyu Li","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Feng Zhu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I177388780","display_name":"Xuzhou Medical College","ror":"https://ror.org/04fe7hy80","country_code":"CN","type":"education","lineage":["https://openalex.org/I177388780"]},{"id":"https://openalex.org/I4210106614","display_name":"Affiliated Hospital of Xuzhou Medical College","ror":"https://ror.org/011xhcs96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210106614"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Feng Zhu","raw_affiliation_strings":["Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Blood Diseases Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I177388780"]},{"raw_affiliation_string":"Department of Hematology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China","institution_ids":["https://openalex.org/I4210106614"]},{"raw_affiliation_string":"Jiangsu Key Laboratory of Bone Marrow Stem Cells, Xuzhou, Jiangsu, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100330758","https://openalex.org/A5101586828"],"corresponding_institution_ids":["https://openalex.org/I177388780","https://openalex.org/I4210105400","https://openalex.org/I4210106614","https://openalex.org/I4405254887"],"apc_list":{"value":3150,"currency":"CHF","value_usd":3801},"apc_paid":{"value":3150,"currency":"CHF","value_usd":3801},"fwci":2.8751,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.91752348,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"16","issue":null,"first_page":"1566016","last_page":"1566016"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.8163999915122986,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research","score":0.8163999915122986,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10649","display_name":"Multiple Myeloma Research and Treatments","score":0.17409999668598175,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10137","display_name":"Multiple Sclerosis Research Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/car-t-cell-therapy","display_name":"CAR T-cell therapy","score":0.9470000267028809},{"id":"https://openalex.org/keywords/antibiotic-use","display_name":"antibiotic use","score":0.8939999938011169},{"id":"https://openalex.org/keywords/prior-antibiotic-use","display_name":"prior antibiotic use","score":0.5870000123977661},{"id":"https://openalex.org/keywords/complete-response-rate","display_name":"complete response rate","score":0.7229999899864197},{"id":"https://openalex.org/keywords/progression-free-survival","display_name":"progression-free survival","score":0.9929999709129333},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9990000128746033},{"id":"https://openalex.org/keywords/car-t-toxicity","display_name":"CAR-T toxicity","score":0.6110000014305115},{"id":"https://openalex.org/keywords/cytokine-release-syndrome","display_name":"cytokine release syndrome","score":0.5889999866485596},{"id":"https://openalex.org/keywords/neurotoxicity","display_name":"neurotoxicity","score":0.8270000219345093},{"id":"https://openalex.org/keywords/immunotherapy-safety-and-efficacy","display_name":"immunotherapy safety and efficacy","score":0.4020000100135803},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.5120000243186951}],"concepts":[{"id":"https://openalex.org/C142424586","wikidata":"https://www.wikidata.org/wiki/Q7307572","display_name":"Refractory (planetary science)","level":2,"score":0.7208045125007629},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6732858419418335},{"id":"https://openalex.org/C2776364478","wikidata":"https://www.wikidata.org/wiki/Q467635","display_name":"Multiple myeloma","level":2,"score":0.6079866290092468},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.48142072558403015},{"id":"https://openalex.org/C2993328841","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotic therapy","level":3,"score":0.4810062348842621},{"id":"https://openalex.org/C2911194787","wikidata":"https://www.wikidata.org/wiki/Q5099363","display_name":"CAR T-cell therapy","level":5,"score":0.46805045008659363},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.42759090662002563},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.4256996512413025},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3926333785057068},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1459921896457672},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.11386582255363464},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.08518043160438538},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06154590845108032},{"id":"https://openalex.org/C3875195","wikidata":"https://www.wikidata.org/wiki/Q5099363","display_name":"Chimeric antigen receptor","level":4,"score":0.053970932960510254},{"id":"https://openalex.org/C87355193","wikidata":"https://www.wikidata.org/wiki/Q411","display_name":"Astrobiology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000076962","descriptor_name":"Receptors, Chimeric Antigen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000900","descriptor_name":"Anti-Bacterial Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D009101","descriptor_name":"Multiple Myeloma","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016219","descriptor_name":"Immunotherapy, Adoptive","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016219","descriptor_name":"Immunotherapy, Adoptive","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.3389/fimmu.2025.1566016","doi":"https://doi.org/10.3389/fimmu.2025.1566016","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2025.1566016","pdf_url":"https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1566016/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12043596","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12043596","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Immunol","raw_type":"Text"},{"id":"pmid:40313953","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40313953","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in immunology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:21e8e926d63f4977b5d08cbda0007f4b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/21e8e926d63f4977b5d08cbda0007f4b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Immunology, Vol 16 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fimmu.2025.1566016","doi":"https://doi.org/10.3389/fimmu.2025.1566016","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fimmu.2025.1566016","pdf_url":"https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2025.1566016/pdf","source":{"id":"https://openalex.org/S2595292759","display_name":"Frontiers in Immunology","issn_l":"1664-3224","issn":["1664-3224"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G2087924680","display_name":null,"funder_award_id":"82170187","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4311164714","display_name":null,"funder_award_id":"81800159","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321605","display_name":"Government of Jiangsu Province","ror":"https://ror.org/004svx814"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409557282.pdf","grobid_xml":"https://content.openalex.org/works/W4409557282.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W2486629951","https://openalex.org/W2807637103","https://openalex.org/W2905654445","https://openalex.org/W2965223724","https://openalex.org/W2981115487","https://openalex.org/W2995658490","https://openalex.org/W3015408469","https://openalex.org/W3109379743","https://openalex.org/W3121241747","https://openalex.org/W3124007401","https://openalex.org/W3164285162","https://openalex.org/W3171198490","https://openalex.org/W3176532045","https://openalex.org/W3202498320","https://openalex.org/W4220783027","https://openalex.org/W4220963121","https://openalex.org/W4221064629","https://openalex.org/W4281714381","https://openalex.org/W4288445670","https://openalex.org/W4295024004","https://openalex.org/W4297519419","https://openalex.org/W4315977392","https://openalex.org/W4318485543","https://openalex.org/W4318922300","https://openalex.org/W4320917309","https://openalex.org/W4321765041","https://openalex.org/W4323351721","https://openalex.org/W4323924547","https://openalex.org/W4324044824","https://openalex.org/W4366428230","https://openalex.org/W4385240643","https://openalex.org/W4386086186","https://openalex.org/W4387241860","https://openalex.org/W4392859468","https://openalex.org/W4394975935","https://openalex.org/W4399295614","https://openalex.org/W4399688015","https://openalex.org/W4400901230","https://openalex.org/W4400951159","https://openalex.org/W4402499383","https://openalex.org/W4403114117","https://openalex.org/W4403674599","https://openalex.org/W4405017042"],"related_works":["https://openalex.org/W6958478074","https://openalex.org/W4405039674","https://openalex.org/W7217373990","https://openalex.org/W3130400555","https://openalex.org/W7204717643","https://openalex.org/W2983551256","https://openalex.org/W4288437751","https://openalex.org/W7119539445","https://openalex.org/W4223630566","https://openalex.org/W3108244232"],"abstract_inverted_index":{"Background":[0],"In":[1,63,128],"recent":[2],"years,":[3],"chimeric":[4],"antigen":[5],"receptor":[6],"(CAR)-T":[7],"cell":[8,120,333],"therapy":[9,121],"has":[10],"achieved":[11],"tremendous":[12],"efficacy":[13],"in":[14,87,103,122,216,290],"relapsed/refractory":[15],"multiple":[16],"myeloma":[17],"(R/R":[18],"MM).":[19],"However,":[20,335],"the":[21,46,51,104,112,129,134,143,184,193,202,229,241,264,336,344],"impact":[22],"of":[23,40,48,54,118,125,259,301,306,326,338,346],"antibiotic":[24],"(ATB)":[25],"use":[26,237,337],"on":[27,50,328],"R/R":[28,55,70,291],"MM":[29,56,71,292],"patients":[30,57,68,293,302],"treated":[31,58,294],"with":[32,59,69,166,295,343],"CAR-T":[33,60,74,119,296,332],"is":[34,340],"still":[35],"not":[36,239,262,341],"known.":[37],"The":[38,154,175,196],"aim":[39],"our":[41],"study":[42],"was":[43,101,139,159,162,180,189],"to":[44,98,142,252,273,285,322,331],"analyse":[45],"influence":[47],"ATB":[49,100,130,145,168,194,204,236,260,327,339],"clinical":[52],"outcomes":[53,115,330],"cells.":[61,297],"Methods":[62],"this":[64],"retrospective":[65],"study,":[66],"199":[67],"who":[72],"received":[73],"cells":[75],"between":[76,228],"January":[77],"2018":[78],"and":[79,94,116,199,209,222,278,311],"December":[80],"2023":[81],"were":[82,90,206,213],"evaluated":[83,230],"from":[84],"two":[85,123],"hospitals":[86],"China.":[88],"They":[89],"stratified":[91],"into":[92],"ATB-group":[93,96],"No":[95,144,167,203],"according":[97],"whether":[99],"administered":[102],"4":[105],"weeks":[106],"before":[107],"therapy.":[108,334],"We":[109],"mainly":[110],"analyzed":[111],"efficacy,":[113],"survival":[114,178,187],"cytotoxicity":[117],"groups":[124,300],"patients.":[126],"Result":[127],"group":[131,146,169,205],"(90":[132],"patients),":[133],"overall":[135,186],"response":[136,156],"rate":[137,157],"(ORR)":[138],"70%":[140],"comparable":[141],"(109":[147],"patients:":[148],"ORR,":[149],"81.7%;":[150],"P":[151,172,219,225,254,275,287],"=":[152,173,220,226,255,276,288],"0.054).":[153],"complete":[155],"(CRR)":[158],"40%,":[160],"which":[161],"significantly":[163],"lower":[164],"compared":[165],"(CRR,":[170],"57.8%;":[171],"0.012).":[174],"median":[176,185,197],"progression-free":[177],"(PFS)":[179],"6.7":[181],"months":[182,191,208],"while":[183],"(OS)":[188],"21.9":[190],"for":[192,201],"group.":[195],"PFS":[198,217,265],"OS":[200,223,279],"13.9":[207],"36.1":[210],"months.":[211],"There":[212],"significant":[214],"differences":[215],"(":[218,224],"0.007)":[221],"0.004)":[227],"groups.":[231],"Nonetheless,":[232],"multivariate":[233],"analysis":[234],"found":[235],"did":[238,261],"reduce":[240],"CRR":[242],"(odds":[243],"ratio":[244,267],"[OR],":[245],"0.947;":[246],"95%":[247,270,282],"confidence":[248],"interval":[249],"[CI],":[250],"0.251":[251],"3.565,":[253],"0.936).":[256],"Besides,":[257],"administration":[258],"affect":[263],"(hazard":[266],"[HR],":[268],"0.634;":[269],"CI,":[271,283],"0.28":[272],"1.436,":[274],"0.275)":[277],"(HR,":[280],"2.259;":[281],"0.755":[284],"6.762,":[286],"0.145)":[289],"Additionally,":[298],"both":[299],"had":[303],"similar":[304],"incidences":[305],"cytokine":[307],"release":[308],"syndrome":[309,316],"(CRS)":[310],"immune":[312],"effector":[313],"cell-associated":[314],"neurotoxicity":[315],"(ICANS).":[317],"Conclusion":[318],"Our":[319],"results":[320],"point":[321],"a":[323],"detrimental":[324],"effect":[325],"treatment":[329],"associated":[342],"incidence":[345],"CRS":[347],"or":[348],"ICANS.":[349]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-04-18T00:00:00"}