{"id":"https://openalex.org/W4409516640","doi":"https://doi.org/10.3389/ftox.2025.1560192","title":"Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus)","display_name":"Exposure to deltamethrin leads to gill liver damage, oxidative stress, inflammation, and metabolic disorders of Japanese flounder (Paralichthys olivaceus)","publication_year":2025,"publication_date":"2025-04-16","ids":{"openalex":"https://openalex.org/W4409516640","doi":"https://doi.org/10.3389/ftox.2025.1560192","pmid":"https://pubmed.ncbi.nlm.nih.gov/40309513","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12041085"},"language":"en","primary_location":{"id":"doi:10.3389/ftox.2025.1560192","doi":"https://doi.org/10.3389/ftox.2025.1560192","is_oa":true,"landing_page_url":"https://doi.org/10.3389/ftox.2025.1560192","pdf_url":"https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2025.1560192/pdf","source":{"id":"https://openalex.org/S4210231588","display_name":"Frontiers in Toxicology","issn_l":"2673-3080","issn":["2673-3080"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Toxicology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2025.1560192/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104197252","display_name":"Bingbu Li","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bingbu Li","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103223815","display_name":"Guixing Wang","orcid":"https://orcid.org/0000-0002-6165-0037","observed_orcids":["https://orcid.org/0000-0002-6165-0037"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guixing Wang","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101388236","display_name":"Xinyu Zheng","orcid":"https://orcid.org/0009-0003-3261-0604","observed_orcids":["https://orcid.org/0009-0003-3261-0604"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinyu Zheng","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100443412","display_name":"Mingyang Liu","orcid":"https://orcid.org/0000-0002-2371-7173","observed_orcids":["https://orcid.org/0000-0002-2371-7173"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mingyang Liu","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076022828","display_name":"Yucong Yang","orcid":"https://orcid.org/0009-0008-5004-6943","observed_orcids":["https://orcid.org/0009-0008-5004-6943"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yucong Yang","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035281183","display_name":"Yuqin Ren","orcid":"https://orcid.org/0000-0003-1572-8371","observed_orcids":["https://orcid.org/0000-0003-1572-8371"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuqin Ren","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100614235","display_name":"Yitong Zhang","orcid":"https://orcid.org/0000-0002-5378-1854","observed_orcids":["https://orcid.org/0000-0002-5378-1854","https://orcid.org/0009-0001-5365-4257"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yitong Zhang","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100376623","display_name":"Yufeng Liu","orcid":"https://orcid.org/0000-0002-8118-4336","observed_orcids":["https://orcid.org/0000-0002-8118-4336"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yufeng Liu","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102729436","display_name":"Zhongwei He","orcid":"https://orcid.org/0000-0001-8487-719X","observed_orcids":["https://orcid.org/0000-0001-8487-719X"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhongwei He","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102155793","display_name":"Jiangong Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiangong Ren","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hailong Wan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I108160477","display_name":"Hebei Agricultural University","ror":"https://ror.org/009fw8j44","country_code":"CN","type":"education","lineage":["https://openalex.org/I108160477"]},{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hailong Wan","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Ocean College, Hebei Agricultural University, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Ocean College, Hebei Agricultural University, Qinhuangdao, China","institution_ids":["https://openalex.org/I108160477"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101910619","display_name":"Wei Cao","orcid":"https://orcid.org/0000-0001-5035-0568","observed_orcids":["https://orcid.org/0000-0001-5035-0568"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Cao","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107879211","display_name":"Yufen Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yufen Wang","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaoyan Zhang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaoyan Zhang","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052990948","display_name":"Jilun Hou","orcid":"https://orcid.org/0000-0003-1370-822X","observed_orcids":["https://orcid.org/0000-0003-1370-822X","https://orcid.org/0000-0003-4379-2426"]},"institutions":[{"id":"https://openalex.org/I46529539","display_name":"Chinese Academy of Fishery Sciences","ror":"https://ror.org/02bwk9n38","country_code":"CN","type":"nonprofit","lineage":["https://openalex.org/I4210127390","https://openalex.org/I4210151987","https://openalex.org/I46529539"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jilun Hou","raw_affiliation_strings":["Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bohai Sea Fishery Research Center, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"Hebei Key Laboratory of the Bohai Sea Fish Germplasm Resources Conservation and Utilization, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]},{"raw_affiliation_string":"State Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Beidaihe Central Experiment Station, Chinese Academy of Fishery Sciences, Qinhuangdao, China","institution_ids":["https://openalex.org/I46529539"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052990948"],"corresponding_institution_ids":["https://openalex.org/I46529539"],"apc_list":{"value":2550,"currency":"CHF","value_usd":3077},"apc_paid":{"value":2550,"currency":"CHF","value_usd":3077},"fwci":5.9562,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.97698515,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"7","issue":null,"first_page":"1560192","last_page":"1560192"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10447","display_name":"Environmental Toxicology and Ecotoxicology","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11180","display_name":"Pesticide and Herbicide Environmental Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2310","display_name":"Pollution"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deltamethrin","display_name":"deltamethrin","score":1.0},{"id":"https://openalex.org/keywords/pyrethroid-insecticides","display_name":"pyrethroid insecticides","score":0.9229999780654907},{"id":"https://openalex.org/keywords/olive-flounder","display_name":"Paralichthys olivaceus","score":1.0},{"id":"https://openalex.org/keywords/gill-damage","display_name":"gill damage","score":0.9800000190734863},{"id":"https://openalex.org/keywords/liver-injury","display_name":"liver injury","score":0.9079999923706055},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9459999799728394},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.8640000224113464},{"id":"https://openalex.org/keywords/immunometabolism","display_name":"immunometabolism","score":0.6259999871253967},{"id":"https://openalex.org/keywords/liver-transcriptome","display_name":"liver transcriptome","score":0.8159999847412109},{"id":"https://openalex.org/keywords/ferroptosis","display_name":"ferroptosis","score":0.8360000252723694},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9710000157356262},{"id":"https://openalex.org/keywords/steroidogenesis","display_name":"steroidogenesis","score":0.6230000257492065},{"id":"https://openalex.org/keywords/enzyme-activity","display_name":"enzyme activity","score":0.49399998784065247},{"id":"https://openalex.org/keywords/fish-toxicity","display_name":"fish toxicity","score":0.4790000021457672}],"concepts":[{"id":"https://openalex.org/C2776459645","wikidata":"https://www.wikidata.org/wiki/Q3011327","display_name":"Paralichthys","level":3,"score":0.9353857040405273},{"id":"https://openalex.org/C2776533291","wikidata":"https://www.wikidata.org/wiki/Q1322753","display_name":"Olive flounder","level":3,"score":0.7973007559776306},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.7837039232254028},{"id":"https://openalex.org/C2776367567","wikidata":"https://www.wikidata.org/wiki/Q4246303","display_name":"Flounder","level":3,"score":0.7204335927963257},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6304854154586792},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3636491298675537},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3180882930755615},{"id":"https://openalex.org/C2909208804","wikidata":"https://www.wikidata.org/wiki/Q127282","display_name":"Fish <Actinopterygii>","level":2,"score":0.3149906098842621},{"id":"https://openalex.org/C505870484","wikidata":"https://www.wikidata.org/wiki/Q180538","display_name":"Fishery","level":1,"score":0.31447553634643555},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2981410622596741},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2629551291465759}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/ftox.2025.1560192","doi":"https://doi.org/10.3389/ftox.2025.1560192","is_oa":true,"landing_page_url":"https://doi.org/10.3389/ftox.2025.1560192","pdf_url":"https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2025.1560192/pdf","source":{"id":"https://openalex.org/S4210231588","display_name":"Frontiers in Toxicology","issn_l":"2673-3080","issn":["2673-3080"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Toxicology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12041085","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12041085","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Toxicol","raw_type":"Text"},{"id":"pmid:40309513","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40309513","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in toxicology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:0958ba317ded49d1bae1507ceec9b546","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/0958ba317ded49d1bae1507ceec9b546","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Toxicology, Vol 7 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/ftox.2025.1560192","doi":"https://doi.org/10.3389/ftox.2025.1560192","is_oa":true,"landing_page_url":"https://doi.org/10.3389/ftox.2025.1560192","pdf_url":"https://www.frontiersin.org/journals/toxicology/articles/10.3389/ftox.2025.1560192/pdf","source":{"id":"https://openalex.org/S4210231588","display_name":"Frontiers in Toxicology","issn_l":"2673-3080","issn":["2673-3080"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Toxicology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2913777509","display_name":null,"funder_award_id":"2023TD41","funder_id":"https://openalex.org/F4320338141","funder_display_name":"Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences"},{"id":"https://openalex.org/G5642745374","display_name":null,"funder_award_id":"CARS-47","funder_id":"https://openalex.org/F4320338141","funder_display_name":"Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences"},{"id":"https://openalex.org/G858407657","display_name":null,"funder_award_id":"21326307D","funder_id":"https://openalex.org/F4320338141","funder_display_name":"Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences"}],"funders":[{"id":"https://openalex.org/F4320338141","display_name":"Central Public-interest Scientific Institution Basal Research Fund, Chinese Academy of Fishery Sciences","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409516640.pdf","grobid_xml":"https://content.openalex.org/works/W4409516640.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W1544443650","https://openalex.org/W1969406497","https://openalex.org/W1979009709","https://openalex.org/W1997040721","https://openalex.org/W1999825515","https://openalex.org/W2035618305","https://openalex.org/W2037395667","https://openalex.org/W2097337885","https://openalex.org/W2104005232","https://openalex.org/W2107277218","https://openalex.org/W2117781543","https://openalex.org/W2138121784","https://openalex.org/W2152239989","https://openalex.org/W2558031922","https://openalex.org/W2602413171","https://openalex.org/W2624134566","https://openalex.org/W2744747999","https://openalex.org/W2761710844","https://openalex.org/W2763661409","https://openalex.org/W2792396619","https://openalex.org/W2901192537","https://openalex.org/W2905350516","https://openalex.org/W2914168227","https://openalex.org/W2969257228","https://openalex.org/W3006533882","https://openalex.org/W3031658933","https://openalex.org/W3048027068","https://openalex.org/W3084644238","https://openalex.org/W3088207389","https://openalex.org/W3101518221","https://openalex.org/W3114702280","https://openalex.org/W3141920883","https://openalex.org/W3159552892","https://openalex.org/W3189603784","https://openalex.org/W3196688642","https://openalex.org/W3207164131","https://openalex.org/W4205618565","https://openalex.org/W4221042802","https://openalex.org/W4281633688","https://openalex.org/W4290999254","https://openalex.org/W4309330588","https://openalex.org/W4313460240","https://openalex.org/W4362460079","https://openalex.org/W4377030973","https://openalex.org/W4382395542","https://openalex.org/W4383873173","https://openalex.org/W4386332892","https://openalex.org/W4396515169","https://openalex.org/W4400241685","https://openalex.org/W4402422086"],"related_works":["https://openalex.org/W2080725371","https://openalex.org/W1997040721","https://openalex.org/W2030370037","https://openalex.org/W2744747999","https://openalex.org/W2014890599","https://openalex.org/W7217092139","https://openalex.org/W2602413171","https://openalex.org/W2012878895","https://openalex.org/W4387753383","https://openalex.org/W3035996149"],"abstract_inverted_index":{"Introduction":[0],"Deltamethrin":[1],"is":[2],"a":[3,67,215,223],"pyrethroid":[4],"insecticide":[5],"commonly":[6],"used":[7],"to":[8,42,104,205],"kill":[9],"animal":[10],"parasites":[11],"in":[12,61,86,179,200,232],"aquaculture.":[13],"However,":[14,207],"increasing":[15],"evidence":[16],"suggests":[17],"that":[18,158,192],"deltamethrin":[19,41,75,193,231],"affects":[20],"the":[21,37,43,71,78,82,87,105,111,150,208,227],"health":[22],"of":[23,74,102,110,119,149,230],"aquatic":[24],"animals":[25],"by":[26,40,129],"causing":[27],"tissue":[28,131],"damage":[29,38,103,213],"and":[30,45,56,77,107,126,139,152,168,184,197,203],"even":[31],"death.":[32],"Methods":[33],"In":[34,188],"this":[35],"study,":[36],"caused":[39],"gill":[44,106,120],"liver":[46,108,123,146],"tissues,":[47],"as":[48,50],"well":[49],"its":[51],"effects":[52],"on":[53],"oxidative":[54,195],"stress":[55,196],"immune":[57],"metabolism,":[58],"were":[59,160,176],"studied":[60],"Paralichthys":[62,112],"olivaceus.":[63,234],"Results":[64],"We":[65],"observed":[66,99],"positive":[68],"correlation":[69],"between":[70],"residual":[72],"levels":[73],"(Del)":[76],"exposure":[79],"concentrations,":[80],"with":[81],"highest":[83],"residue":[84],"detected":[85],"0.28":[88],"\u03bcg/L":[89],"concentration":[90],"group":[91],"(0.0684":[92],"mg/kg":[93],"at":[94],"7":[95],"days).":[96],"Then,":[97],"we":[98,190],"different":[100],"degrees":[101],"tissues":[109],"olivaceus,":[113],"including":[114,165],"swelling,":[115],"apical":[116],"fusion,":[117],"shedding":[118],"secondary":[121],"lamellae,":[122],"cell":[124],"necrosis,":[125],"nuclear":[127],"vacuolization,":[128],"observing":[130],"sections.":[132],"Lysozyme":[133],"enzyme":[134,142],"activity":[135],"increased,":[136],"whereas":[137],"catalase":[138],"alkaline":[140],"phosphatase":[141],"activities":[143],"decreased.":[144],"The":[145],"transcriptome":[147],"results":[148,221],"control":[151],"high-concentration":[153],"(0.28":[154],"\u03bcg/L)":[155],"groups":[156],"showed":[157],"there":[159],"697":[161],"differentially":[162,173],"expressed":[163,174],"genes,":[164],"390":[166],"upregulated":[167],"307":[169],"downregulated":[170],"genes.":[171],"These":[172,219],"genes":[175],"significantly":[177],"enriched":[178],"oxidation-reduction,":[180],"ferroptosis,":[181],"steroid":[182],"biosynthesis,":[183],"apoptosis":[185],"pathways.":[186],"Discussion":[187],"summary,":[189],"found":[191],"induces":[194],"metabolic":[198],"disorders":[199],"P.":[201,233],"olivaceus":[202],"leads":[204],"inflammation.":[206],"fish":[209],"body":[210],"resists":[211],"such":[212],"through":[214],"complex":[216],"regulatory":[217],"network.":[218],"experimental":[220],"provide":[222],"theoretical":[224],"reference":[225],"for":[226],"safe":[228],"use":[229]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2025-04-17T00:00:00"}
