{"id":"https://openalex.org/W4409505147","doi":"https://doi.org/10.52711/0975-4377.2025.00004","title":"The Exosome Revolution: Bridging Early Detection and Personalized Treatment","display_name":"The Exosome Revolution: Bridging Early Detection and Personalized Treatment","publication_year":2025,"publication_date":"2025-03-10","ids":{"openalex":"https://openalex.org/W4409505147","doi":"https://doi.org/10.52711/0975-4377.2025.00004"},"language":"en","primary_location":{"id":"doi:10.52711/0975-4377.2025.00004","doi":"https://doi.org/10.52711/0975-4377.2025.00004","is_oa":false,"landing_page_url":"https://doi.org/10.52711/0975-4377.2025.00004","pdf_url":null,"source":{"id":"https://openalex.org/S2765058431","display_name":"Research Journal of Pharmaceutical Dosage Forms and Technology","issn_l":"0975-234X","issn":["0975-234X","0975-4377"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research Journal of Pharmaceutical Dosage Forms and Technology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Khushi Kiranbhai Patel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Khushi Kiranbhai Patel","raw_affiliation_strings":["Smt. B.N.B Swaminarayan Pharmacy College, Salvav - Vapi, Gujarat, 396191"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Smt. B.N.B Swaminarayan Pharmacy College, Salvav - Vapi, Gujarat, 396191","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104301479","display_name":"Bhoomi S. Patel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29563240","display_name":"Gujarat Technological University","ror":"https://ror.org/059x8vm09","country_code":"IN","type":"education","lineage":["https://openalex.org/I29563240"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bhoomi S. Patel","raw_affiliation_strings":["Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191","institution_ids":["https://openalex.org/I29563240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020408661","display_name":"Anuradha Parixit Prajapati","orcid":"https://orcid.org/0000-0001-6044-9676","observed_orcids":["https://orcid.org/0000-0001-6044-9676"]},"institutions":[{"id":"https://openalex.org/I29563240","display_name":"Gujarat Technological University","ror":"https://ror.org/059x8vm09","country_code":"IN","type":"education","lineage":["https://openalex.org/I29563240"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anuradha Prajapati","raw_affiliation_strings":["Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191","institution_ids":["https://openalex.org/I29563240"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112002255","display_name":"Sachin B. Narkhede","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29563240","display_name":"Gujarat Technological University","ror":"https://ror.org/059x8vm09","country_code":"IN","type":"education","lineage":["https://openalex.org/I29563240"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sachin B. Narkhede","raw_affiliation_strings":["Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191","institution_ids":["https://openalex.org/I29563240"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053048235","display_name":"Shailesh Luhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29563240","display_name":"Gujarat Technological University","ror":"https://ror.org/059x8vm09","country_code":"IN","type":"education","lineage":["https://openalex.org/I29563240"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Shailesh Luhar","raw_affiliation_strings":["Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutics, Smt. BNB Swaminarayan Pharmacy College,  Gujarat Technological University, Salvav, Vapi, Gujarat, India, 396191","institution_ids":["https://openalex.org/I29563240"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4415,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.47558978,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"26","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exosomes","display_name":"exosomes","score":0.996999979019165},{"id":"https://openalex.org/keywords/extracellular-vesicles","display_name":"extracellular vesicles","score":0.9990000128746033},{"id":"https://openalex.org/keywords/early-disease-detection","display_name":"early disease detection","score":0.6779999732971191},{"id":"https://openalex.org/keywords/non-invasive-diagnosis","display_name":"non-invasive diagnosis","score":0.7200000286102295},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"personalized medicine","score":0.8519999980926514},{"id":"https://openalex.org/keywords/exosome-isolation","display_name":"exosome isolation","score":0.5879999995231628},{"id":"https://openalex.org/keywords/exosome-biomarkers","display_name":"exosomal biomarkers","score":0.722000002861023},{"id":"https://openalex.org/keywords/cancer-diagnosis","display_name":"cancer diagnosis","score":0.6150000095367432},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.9399999976158142},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.843999981880188},{"id":"https://openalex.org/keywords/targeted-drug-delivery","display_name":"targeted drug delivery","score":0.7200000286102295},{"id":"https://openalex.org/keywords/rna-delivery","display_name":"RNA delivery","score":0.6389999985694885},{"id":"https://openalex.org/keywords/clinical-translation","display_name":"clinical translation","score":0.6830000281333923}],"concepts":[{"id":"https://openalex.org/C2781261824","wikidata":"https://www.wikidata.org/wiki/Q903634","display_name":"Exosome","level":5,"score":0.7478979825973511},{"id":"https://openalex.org/C174348530","wikidata":"https://www.wikidata.org/wiki/Q188635","display_name":"Bridging (networking)","level":2,"score":0.6819857358932495},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4727666676044464},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3610644042491913},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3569633364677429},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3495182394981384},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3416966199874878},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32512223720550537},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3225141167640686},{"id":"https://openalex.org/C20518536","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicles","level":4,"score":0.18120095133781433},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.11448535323143005},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.10011816024780273},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0898418128490448},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.52711/0975-4377.2025.00004","doi":"https://doi.org/10.52711/0975-4377.2025.00004","is_oa":false,"landing_page_url":"https://doi.org/10.52711/0975-4377.2025.00004","pdf_url":null,"source":{"id":"https://openalex.org/S2765058431","display_name":"Research Journal of Pharmaceutical Dosage Forms and Technology","issn_l":"0975-234X","issn":["0975-234X","0975-4377"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research Journal of Pharmaceutical Dosage Forms and Technology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1974954833","https://openalex.org/W2072167135","https://openalex.org/W2143729276","https://openalex.org/W2153241061","https://openalex.org/W2170852633","https://openalex.org/W2171672500","https://openalex.org/W2179058806","https://openalex.org/W2290891464","https://openalex.org/W2328577036","https://openalex.org/W2547441299","https://openalex.org/W2553388940","https://openalex.org/W2765371030","https://openalex.org/W2786514708","https://openalex.org/W2931418311","https://openalex.org/W3217475513","https://openalex.org/W4220703150","https://openalex.org/W4390127577"],"related_works":["https://openalex.org/W4391784532","https://openalex.org/W4417297702","https://openalex.org/W4405730174","https://openalex.org/W7138386662","https://openalex.org/W7128473252","https://openalex.org/W7168534011","https://openalex.org/W4412783149","https://openalex.org/W4408417743","https://openalex.org/W6911603690","https://openalex.org/W4409559173"],"abstract_inverted_index":{"Exosomes,":[0],"small":[1,122],"extracellular":[2],"vesicles,":[3],"have":[4,64],"garnered":[5],"attention":[6],"for":[7,43,73,93,114],"their":[8,66,152],"significant":[9],"role":[10,134,174],"in":[11,55,105,124,137,151,175],"diagnostics":[12,164],"and":[13,25,51,61,78,103,141,154,165],"personalized":[14,84],"medicine.":[15],"Released":[16],"by":[17],"cells,":[18],"they":[19],"contain":[20],"biomolecules":[21],"like":[22],"proteins,":[23,120],"lipids,":[24],"nucleic":[26],"acids":[27],"that":[28],"mirror":[29],"the":[30,36,56,81,132,148,161,176],"health":[31],"or":[32,121],"disease":[33,76],"status":[34],"of":[35,83,135,163,178],"source":[37],"cells.":[38],"This":[39,128],"makes":[40],"exosomes":[41,63,86,136,167],"valuable":[42],"detecting":[44],"diseases":[45],"early,":[46],"including":[47],"cancer,":[48],"neurodegenerative":[49],"disorders,":[50],"cardiovascular":[52],"conditions.":[53],"Advances":[54],"methods":[57],"used":[58],"to":[59,99,156,170],"isolate":[60],"analyze":[62],"highlighted":[65],"potential":[67,89],"as":[68,90,111,118],"non-invasive":[69],"diagnostic":[70],"tools,":[71],"allowing":[72],"more":[74],"accurate":[75],"detection":[77],"monitoring.":[79],"In":[80],"realm":[82],"treatment,":[85],"offer":[87],"promising":[88],"delivery":[91],"vehicles":[92],"targeted":[94],"therapies.":[95],"Their":[96],"natural":[97],"ability":[98],"cross":[100],"biological":[101],"barriers":[102],"home":[104],"on":[106],"specific":[107],"tissues":[108],"positions":[109],"them":[110],"ideal":[112],"candidates":[113],"delivering":[115],"treatments,":[116],"such":[117],"RNA,":[119],"molecules,":[123],"precision":[125],"medicine":[126],"approaches.":[127],"review":[129],"delves":[130],"into":[131],"evolving":[133],"both":[138],"early":[139],"diagnosis":[140],"tailored":[142],"therapeutic":[143],"interventions,":[144],"while":[145],"also":[146],"addressing":[147],"existing":[149],"challenges":[150],"application":[153],"translation":[155],"clinical":[157],"practice.":[158],"By":[159],"uniting":[160],"fields":[162],"therapeutics,":[166],"are":[168],"set":[169],"play":[171],"a":[172],"crucial":[173],"future":[177],"healthcare.":[179]},"counts_by_year":[{"year":2026,"cited_by_count":2}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2025-04-17T00:00:00"}