{"id":"https://openalex.org/W4409465747","doi":"https://doi.org/10.1093/cid/ciaf082","title":"Retreatment of Hepatitis C Virus Among People Who Inject Drugs","display_name":"Retreatment of Hepatitis C Virus Among People Who Inject Drugs","publication_year":2025,"publication_date":"2025-03-30","ids":{"openalex":"https://openalex.org/W4409465747","doi":"https://doi.org/10.1093/cid/ciaf082","pmid":"https://pubmed.ncbi.nlm.nih.gov/40230037"},"language":"en","primary_location":{"id":"doi:10.1093/cid/ciaf082","doi":"https://doi.org/10.1093/cid/ciaf082","is_oa":false,"landing_page_url":"https://doi.org/10.1093/cid/ciaf082","pdf_url":null,"source":{"id":"https://openalex.org/S72350973","display_name":"Clinical Infectious Diseases","issn_l":"1058-4838","issn":["1058-4838","1537-6591"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049119413","display_name":"Aurielle M Thomas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I17626003","display_name":"University of Rhode Island","ror":"https://ror.org/013ckk937","country_code":"US","type":"education","lineage":["https://openalex.org/I17626003"]},{"id":"https://openalex.org/I2800640726","display_name":"Miriam Hospital","ror":"https://ror.org/053exzj86","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2800640726"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Aurielle M Thomas","raw_affiliation_strings":["Department of Pharmacy Practice and Clinical Research, University of Rhode Island , Kingston, Rhode Island ,","Division of Infectious Diseases, The Miriam Hospital , Providence, Rhode Island ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy Practice and Clinical Research, University of Rhode Island , Kingston, Rhode Island ,","institution_ids":["https://openalex.org/I17626003"]},{"raw_affiliation_string":"Division of Infectious Diseases, The Miriam Hospital , Providence, Rhode Island ,","institution_ids":["https://openalex.org/I2800640726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073065098","display_name":"Alain H. Litwin","orcid":"https://orcid.org/0000-0002-6717-0288","observed_orcids":["https://orcid.org/0000-0002-6717-0288"]},"institutions":[{"id":"https://openalex.org/I1283654650","display_name":"Prisma Health","ror":"https://ror.org/03n7vd314","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283654650"]},{"id":"https://openalex.org/I155781252","display_name":"University of South Carolina","ror":"https://ror.org/02b6qw903","country_code":"US","type":"education","lineage":["https://openalex.org/I155781252"]},{"id":"https://openalex.org/I8078737","display_name":"Clemson University","ror":"https://ror.org/037s24f05","country_code":"US","type":"education","lineage":["https://openalex.org/I8078737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alain H Litwin","raw_affiliation_strings":["Department of Medicine at Prisma Health, Clemson University School of Health Research , Clemson, South Carolina ,","Department of Medicine, Prisma Health , Greenville, South Carolina ,","Department of Medicine, University of South Carolina School of Medicine , Greenville, South Carolina ,"],"raw_orcid":"https://orcid.org/0000-0002-6717-0288","affiliations":[{"raw_affiliation_string":"Department of Medicine at Prisma Health, Clemson University School of Health Research , Clemson, South Carolina ,","institution_ids":["https://openalex.org/I1283654650","https://openalex.org/I8078737"]},{"raw_affiliation_string":"Department of Medicine, Prisma Health , Greenville, South Carolina ,","institution_ids":["https://openalex.org/I1283654650"]},{"raw_affiliation_string":"Department of Medicine, University of South Carolina School of Medicine , Greenville, South Carolina ,","institution_ids":["https://openalex.org/I155781252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076117109","display_name":"Judith I. Tsui","orcid":"https://orcid.org/0000-0003-0877-5399","observed_orcids":["https://orcid.org/0000-0003-0877-5399"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judith I Tsui","raw_affiliation_strings":["Division of General Internal Medicine, University of Washington , Seattle, Washington ,"],"raw_orcid":"https://orcid.org/0000-0003-0877-5399","affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, University of Washington , Seattle, Washington ,","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080742011","display_name":"Sophie Sprecht-Walsh","orcid":"https://orcid.org/0009-0001-0023-1592","observed_orcids":["https://orcid.org/0009-0001-0023-1592"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sophie Sprecht-Walsh","raw_affiliation_strings":["CODAC Behavioral Health , Providence, Rhode Island ,"],"raw_orcid":"https://orcid.org/0009-0001-0023-1592","affiliations":[{"raw_affiliation_string":"CODAC Behavioral Health , Providence, Rhode Island ,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041086448","display_name":"Kendra L. Blalock","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210093664","display_name":"Comagine Health","ror":"https://ror.org/007476v46","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210093664"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kendra L Blalock","raw_affiliation_strings":["Comangine Health, Data Solutions , Seattle, Washington ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comangine Health, Data Solutions , Seattle, Washington ,","institution_ids":["https://openalex.org/I4210093664"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038522202","display_name":"Karen T. Tashima","orcid":"https://orcid.org/0000-0002-1211-3120","observed_orcids":["https://orcid.org/0000-0002-1211-3120"]},"institutions":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen T Tashima","raw_affiliation_strings":["Department of Medicine, Brown University , Providence, Rhode Island ,"],"raw_orcid":"https://orcid.org/0000-0002-1211-3120","affiliations":[{"raw_affiliation_string":"Department of Medicine, Brown University , Providence, Rhode Island ,","institution_ids":["https://openalex.org/I27804330"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014397177","display_name":"Paula J. Lum","orcid":"https://orcid.org/0000-0002-0833-8642","observed_orcids":["https://orcid.org/0000-0002-0833-8642"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paula J Lum","raw_affiliation_strings":["Department of Medicine, University of California, San Francisco , San Francisco, California ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of California, San Francisco , San Francisco, California ,","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023499969","display_name":"Judith Feinberg","orcid":"https://orcid.org/0000-0003-4206-7214","observed_orcids":["https://orcid.org/0000-0003-4206-7214"]},"institutions":[{"id":"https://openalex.org/I12097938","display_name":"West Virginia University","ror":"https://ror.org/011vxgd24","country_code":"US","type":"education","lineage":["https://openalex.org/I12097938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Judith Feinberg","raw_affiliation_strings":["Department of Behavioral Medicine & Psychiatry and Department of Medicine, Infectious Diseases, West Virginia University School of Medicine , Morgantown, West Virginia ,"],"raw_orcid":"https://orcid.org/0000-0003-4206-7214","affiliations":[{"raw_affiliation_string":"Department of Behavioral Medicine & Psychiatry and Department of Medicine, Infectious Diseases, West Virginia University School of Medicine , Morgantown, West Virginia ,","institution_ids":["https://openalex.org/I12097938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084651973","display_name":"Kimberly  Ann Page","orcid":"https://orcid.org/0000-0002-7120-1673","observed_orcids":["https://orcid.org/0000-0002-7120-1673"]},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]},{"id":"https://openalex.org/I4405255059","display_name":"University of New Mexico Health Sciences Center","ror":"https://ror.org/02jvjmd55","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973","https://openalex.org/I4405255059"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly Page","raw_affiliation_strings":["Department of Internal Medicine, University of New Mexico Health Sciences Center , Albuquerque, New Mexico ,"],"raw_orcid":"https://orcid.org/0000-0002-7120-1673","affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of New Mexico Health Sciences Center , Albuquerque, New Mexico ,","institution_ids":["https://openalex.org/I169521973","https://openalex.org/I4405255059"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013317411","display_name":"Shruti H. Mehta","orcid":"https://orcid.org/0000-0002-2523-0959","observed_orcids":["https://orcid.org/0000-0002-2523-0959"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shruti H Mehta","raw_affiliation_strings":["Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland ,"],"raw_orcid":"https://orcid.org/0000-0002-2523-0959","affiliations":[{"raw_affiliation_string":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland ,","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001744575","display_name":"Arthur Y. Kim","orcid":"https://orcid.org/0000-0003-4712-2657","observed_orcids":["https://orcid.org/0000-0003-4712-2657"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Arthur Y Kim","raw_affiliation_strings":["Division of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School , Boston, Massachusetts ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases, Massachusetts General Hospital and Harvard Medical School , Boston, Massachusetts ,","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013294580","display_name":"Brianna L. Norton","orcid":"https://orcid.org/0000-0002-8287-2245","observed_orcids":["https://orcid.org/0000-0002-8287-2245"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I1335289525","display_name":"Montefiore Medical Center","ror":"https://ror.org/044ntvm43","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335289525","https://openalex.org/I19772626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brianna L Norton","raw_affiliation_strings":["Department of Medicine, Montefiore Medical Center/Albert Einstein College of Medicine , Bronx, New York ,"],"raw_orcid":"https://orcid.org/0000-0002-8287-2245","affiliations":[{"raw_affiliation_string":"Department of Medicine, Montefiore Medical Center/Albert Einstein College of Medicine , Bronx, New York ,","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I1335289525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022129366","display_name":"Moonseong Heo","orcid":"https://orcid.org/0000-0001-7711-1209","observed_orcids":["https://orcid.org/0000-0001-7711-1209"]},"institutions":[{"id":"https://openalex.org/I8078737","display_name":"Clemson University","ror":"https://ror.org/037s24f05","country_code":"US","type":"education","lineage":["https://openalex.org/I8078737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Moonseong Heo","raw_affiliation_strings":["Department of Public Health Sciences, Clemson University , Clemson, South Carolina ,"],"raw_orcid":"https://orcid.org/0000-0001-7711-1209","affiliations":[{"raw_affiliation_string":"Department of Public Health Sciences, Clemson University , Clemson, South Carolina ,","institution_ids":["https://openalex.org/I8078737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075091665","display_name":"Ellen S. Stein","orcid":"https://orcid.org/0000-0003-3864-4891","observed_orcids":["https://orcid.org/0000-0003-3864-4891"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ellen S Stein","raw_affiliation_strings":["Department of Medicine, University of California, San Francisco , San Francisco, California ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of California, San Francisco , San Francisco, California ,","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012598751","display_name":"Cristina M. Murray-Krezan","orcid":"https://orcid.org/0000-0002-5488-1080","observed_orcids":["https://orcid.org/0000-0002-5488-1080"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cristina Murray-Krezan","raw_affiliation_strings":["Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania ,"],"raw_orcid":"https://orcid.org/0000-0002-5488-1080","affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Pittsburgh , Pittsburgh, Pennsylvania ,","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028743057","display_name":"Julia Hope Arnsten","orcid":"https://orcid.org/0000-0002-7741-1567","observed_orcids":["https://orcid.org/0000-0002-7741-1567"]},"institutions":[{"id":"https://openalex.org/I129975664","display_name":"Albert Einstein College of Medicine","ror":"https://ror.org/05cf8a891","country_code":"US","type":"education","lineage":["https://openalex.org/I129975664","https://openalex.org/I4210112371"]},{"id":"https://openalex.org/I1335289525","display_name":"Montefiore Medical Center","ror":"https://ror.org/044ntvm43","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1335289525","https://openalex.org/I19772626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julia Arnsten","raw_affiliation_strings":["Department of Medicine, Montefiore Medical Center/Albert Einstein College of Medicine , Bronx, New York ,"],"raw_orcid":"https://orcid.org/0000-0002-7741-1567","affiliations":[{"raw_affiliation_string":"Department of Medicine, Montefiore Medical Center/Albert Einstein College of Medicine , Bronx, New York ,","institution_ids":["https://openalex.org/I129975664","https://openalex.org/I1335289525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109809023","display_name":"Megan Groome","orcid":"https://orcid.org/0009-0004-4869-6235","observed_orcids":["https://orcid.org/0009-0004-4869-6235"]},"institutions":[{"id":"https://openalex.org/I1283654650","display_name":"Prisma Health","ror":"https://ror.org/03n7vd314","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283654650"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan Groome","raw_affiliation_strings":["Department of Medicine, Prisma Health , Greenville, South Carolina ,"],"raw_orcid":"https://orcid.org/0009-0004-4869-6235","affiliations":[{"raw_affiliation_string":"Department of Medicine, Prisma Health , Greenville, South Carolina ,","institution_ids":["https://openalex.org/I1283654650"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Emily Waters","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I155781252","display_name":"University of South Carolina","ror":"https://ror.org/02b6qw903","country_code":"US","type":"education","lineage":["https://openalex.org/I155781252"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily Waters","raw_affiliation_strings":["Department of Medicine, University of South Carolina School of Medicine , Greenville, South Carolina ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of South Carolina School of Medicine , Greenville, South Carolina ,","institution_ids":["https://openalex.org/I155781252"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083181792","display_name":"Lynn E. Taylor","orcid":"https://orcid.org/0000-0002-0472-8125","observed_orcids":["https://orcid.org/0000-0002-0472-8125"]},"institutions":[{"id":"https://openalex.org/I17626003","display_name":"University of Rhode Island","ror":"https://ror.org/013ckk937","country_code":"US","type":"education","lineage":["https://openalex.org/I17626003"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lynn E Taylor","raw_affiliation_strings":["Department of Medicine, HealthFirst Family Care Center Inc. , Fall River, Massachusetts ,","Department of Pharmacy Practice and Clinical Research, University of Rhode Island , Kingston, Rhode Island ,"],"raw_orcid":"https://orcid.org/0000-0002-0472-8125","affiliations":[{"raw_affiliation_string":"Department of Medicine, HealthFirst Family Care Center Inc. , Fall River, Massachusetts ,","institution_ids":[]},{"raw_affiliation_string":"Department of Pharmacy Practice and Clinical Research, University of Rhode Island , Kingston, Rhode Island ,","institution_ids":["https://openalex.org/I17626003"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":18,"corresponding_author_ids":["https://openalex.org/A5049119413"],"corresponding_institution_ids":["https://openalex.org/I17626003","https://openalex.org/I2800640726"],"apc_list":{"value":4763,"currency":"USD","value_usd":4763},"apc_paid":null,"fwci":2.4243,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.8946721,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"81","issue":"5","first_page":"923","last_page":"930"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11860","display_name":"HIV, Drug Use, Sexual Risk","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hepatitis-c-virus","display_name":"hepatitis C virus","score":0.9390000104904175},{"id":"https://openalex.org/keywords/retreatment","display_name":"retreatment","score":0.7710000276565552},{"id":"https://openalex.org/keywords/people-who-inject-drugs","display_name":"people who inject drugs","score":0.9980000257492065},{"id":"https://openalex.org/keywords/direct-acting-antivirals","display_name":"direct-acting antivirals","score":0.9900000095367432},{"id":"https://openalex.org/keywords/sofosbuvir-velpatasvir","display_name":"sofosbuvir/velpatasvir","score":0.9909999966621399},{"id":"https://openalex.org/keywords/sustained-virologic-response","display_name":"sustained virological response","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hcv-reinfection","display_name":"HCV reinfection","score":0.9639999866485596},{"id":"https://openalex.org/keywords/treatment-naive-patients","display_name":"treatment-naive patients","score":0.5249999761581421},{"id":"https://openalex.org/keywords/opioid-treatment-programs","display_name":"opioid treatment programs","score":0.7730000019073486}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.935505747795105},{"id":"https://openalex.org/C191093355","wikidata":"https://www.wikidata.org/wiki/Q9250577","display_name":"Exact test","level":2,"score":0.6023375391960144},{"id":"https://openalex.org/C2781413609","wikidata":"https://www.wikidata.org/wiki/Q7308373","display_name":"Regimen","level":2,"score":0.5680917501449585},{"id":"https://openalex.org/C2776455275","wikidata":"https://www.wikidata.org/wiki/Q154869","display_name":"Hepatitis C","level":2,"score":0.558059573173523},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5481130480766296},{"id":"https://openalex.org/C2778390639","wikidata":"https://www.wikidata.org/wiki/Q2502747","display_name":"Sofosbuvir","level":5,"score":0.544734001159668},{"id":"https://openalex.org/C2776408679","wikidata":"https://www.wikidata.org/wiki/Q708693","display_name":"Hepatitis C virus","level":3,"score":0.5292060971260071},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2339130938053131},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.1675296425819397},{"id":"https://openalex.org/C2780040827","wikidata":"https://www.wikidata.org/wiki/Q421862","display_name":"Ribavirin","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000069474","descriptor_name":"Sofosbuvir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000069474","descriptor_name":"Sofosbuvir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000069474","descriptor_name":"Sofosbuvir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000069474","descriptor_name":"Sofosbuvir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D000072230","descriptor_name":"Sustained Virologic Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072230","descriptor_name":"Sustained Virologic Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072230","descriptor_name":"Sustained Virologic Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072230","descriptor_name":"Sustained Virologic Response","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006526","descriptor_name":"Hepatitis C","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006576","descriptor_name":"Heterocyclic Compounds, 4 or More Rings","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015819","descriptor_name":"Substance Abuse, Intravenous","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015819","descriptor_name":"Substance Abuse, Intravenous","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015819","descriptor_name":"Substance Abuse, Intravenous","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015819","descriptor_name":"Substance Abuse, Intravenous","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D016174","descriptor_name":"Hepacivirus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016174","descriptor_name":"Hepacivirus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016174","descriptor_name":"Hepacivirus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D016174","descriptor_name":"Hepacivirus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019233","descriptor_name":"Retreatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019233","descriptor_name":"Retreatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019233","descriptor_name":"Retreatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019233","descriptor_name":"Retreatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/cid/ciaf082","doi":"https://doi.org/10.1093/cid/ciaf082","is_oa":false,"landing_page_url":"https://doi.org/10.1093/cid/ciaf082","pdf_url":null,"source":{"id":"https://openalex.org/S72350973","display_name":"Clinical Infectious Diseases","issn_l":"1058-4838","issn":["1058-4838","1537-6591"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Infectious Diseases","raw_type":"journal-article"},{"id":"pmid:40230037","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40230037","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical infectious diseases : an official publication of the Infectious Diseases Society of America","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8600000143051147}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8613598402","display_name":null,"funder_award_id":"award number HPC-1503-28122","funder_id":"https://openalex.org/F4320308927","funder_display_name":"Patient-Centered Outcomes Research Institute"}],"funders":[{"id":"https://openalex.org/F4320308573","display_name":"Gilead Sciences","ror":"https://ror.org/056546b03"},{"id":"https://openalex.org/F4320308927","display_name":"Patient-Centered Outcomes Research Institute","ror":"https://ror.org/014q65q44"},{"id":"https://openalex.org/F4320315955","display_name":"Quest Diagnostics","ror":"https://ror.org/010g9bb70"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W2288320856","https://openalex.org/W2617500612","https://openalex.org/W2765348434","https://openalex.org/W2951737729","https://openalex.org/W2981555580","https://openalex.org/W3092753669","https://openalex.org/W3133598554","https://openalex.org/W4206555576","https://openalex.org/W4280511719","https://openalex.org/W4292291675","https://openalex.org/W4296986239","https://openalex.org/W4308746909","https://openalex.org/W4382630906","https://openalex.org/W4396851988"],"related_works":["https://openalex.org/W2542141975","https://openalex.org/W3108852251","https://openalex.org/W2612959941","https://openalex.org/W4249264895","https://openalex.org/W4249154268","https://openalex.org/W2117027295","https://openalex.org/W2116839874","https://openalex.org/W2762048449","https://openalex.org/W2052290779","https://openalex.org/W1979664732"],"abstract_inverted_index":{"BACKGROUND:":[0],"Hepatitis":[1],"C":[2],"virus":[3],"(HCV)":[4],"is":[5,253],"a":[6,59],"leading":[7],"cause":[8],"of":[9,52,72],"infectious":[10],"disease":[11],"death":[12],"in":[13,66,81],"the":[14,56,140,174,222],"United":[15],"States.":[16],"Although":[17],"highly":[18],"effective":[19],"direct-acting":[20],"antiviral":[21],"(DAA)":[22],"regimens":[23],"are":[24],"well":[25],"established,":[26],"retreatment":[27,43,98,178,197,252],"among":[28,77],"people":[29],"who":[30,113,176,191],"inject":[31],"drugs":[32],"(PWID)":[33],"has":[34],"not":[35,116,193,218],"been":[36],"sufficiently":[37],"studied.":[38],"This":[39,109],"study":[40],"assessed":[41],"DAA":[42,78,224,235],"outcomes":[44],"and":[45,85,136,148,179,241,244],"associated":[46],"factors.":[47],"METHODS:":[48],"We":[49,128],"performed":[50],"analyses":[51],"longitudinal":[53],"data":[54],"from":[55,101],"HERO":[57,90],"Study,":[58],"US-based":[60],"multi-site":[61],"pragmatic":[62],"randomized":[63],"trial":[64],"conducted":[65],"8":[67],"states":[68],"to":[69,105],"evaluate":[70],"effectiveness":[71],"2":[73,142],"HCV":[74,126,239],"care":[75],"models":[76],"treatment-na\u00efve":[79],"PWID":[80,227,248],"opioid":[82],"treatment":[83],"programs":[84],"community":[86],"clinics.":[87],"After":[88,215],"initial":[89,234],"Study":[91],"sofosbuvir/velpatasvir":[92],"(SOF/VEL)":[93],"treatment,":[94],"participants":[95,112,159,201],"eligible":[96,163],"for":[97,146,164,180],"were":[99,123,160,184],"identified,":[100],"15":[102],"September":[103,107],"2016":[104],"13":[106],"2021.":[108],"analysis":[110],"characterizes":[111],"either":[114],"did":[115,192],"achieve":[117,194],"sustained":[118],"virologic":[119],"response":[120],"(SVR)":[121],"or":[122,217],"reinfected":[124,202],"with":[125,221,233,249],"post-SVR.":[127],"compared":[129],"categorical":[130],"variables":[131,138],"using":[132,139],"Fisher":[133],"exact":[134],"test":[135,145],"continuous":[137],"Welch":[141],"sample":[143],"t":[144],"means":[147],"an":[149],"asymptotic":[150],"2-sample":[151],"Mood":[152],"median":[153],"test.":[154],"RESULTS:":[155],"One":[156],"hundred":[157],"four":[158],"identified":[161],"as":[162],"retreatment.":[165,172],"Less":[166],"than":[167,200,232],"half,":[168],"43":[169],"(41.3%),":[170],"initiated":[171,177,196],"Among":[173],"25":[175],"whom":[181],"SVR":[182,188,195,220,230],"results":[183],"available,":[185],"24":[186],"achieved":[187,228],"(96%).":[189],"Participants":[190],"more":[198],"promptly":[199],"post-SVR":[203],"(respectively,":[204],"471":[205],"vs":[206],"784":[207],"days":[208],"on":[209],"average,":[210],"P":[211],"<":[212],".001).":[213],"CONCLUSIONS:":[214],"reinfection":[216],"achieving":[219],"first":[223],"regimen,":[225],"retreated":[226],"higher":[229],"rates":[231],"treatment.":[236],"To":[237],"attain":[238],"elimination":[240],"benefit":[242],"individual":[243],"public":[245],"health,":[246],"assisting":[247],"accessing":[250],"prompt":[251],"crucial.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-10-10T00:00:00"}