{"id":"https://openalex.org/W4409463520","doi":"https://doi.org/10.7759/cureus.82280","title":"Puberty-Onset Selective Mutism in a Female Adolescent With Autism Spectrum Disorder","display_name":"Puberty-Onset Selective Mutism in a Female Adolescent With Autism Spectrum Disorder","publication_year":2025,"publication_date":"2025-04-15","ids":{"openalex":"https://openalex.org/W4409463520","doi":"https://doi.org/10.7759/cureus.82280","pmid":"https://pubmed.ncbi.nlm.nih.gov/40376346","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12079171"},"language":"en","primary_location":{"id":"doi:10.7759/cureus.82280","doi":"https://doi.org/10.7759/cureus.82280","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.82280","pdf_url":"https://assets.cureus.com/uploads/case_report/pdf/357742/20250415-198737-j9bit8.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4409463520"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://assets.cureus.com/uploads/case_report/pdf/357742/20250415-198737-j9bit8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076344852","display_name":"Tiago Nunes Soares","orcid":"https://orcid.org/0000-0002-7795-8116","observed_orcids":["https://orcid.org/0000-0002-7795-8116"]},"institutions":[{"id":"https://openalex.org/I4210110056","display_name":"Administra\u00e7\u00e3o Regional de Sa\u00fade de Lisboa e Vale do Tejo","ror":"https://ror.org/0208sdr22","country_code":"PT","type":"government","lineage":["https://openalex.org/I4210110056"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Tiago Soares","raw_affiliation_strings":["Department of Child and Adolescent Psychiatry, Local Health Unit of Western Lisbon, Lisbon, PRT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Child and Adolescent Psychiatry, Local Health Unit of Western Lisbon, Lisbon, PRT","institution_ids":["https://openalex.org/I4210110056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014763923","display_name":"Joana Vieira dos Santos","orcid":"https://orcid.org/0000-0003-2612-8056","observed_orcids":["https://orcid.org/0000-0003-2612-8056"]},"institutions":[{"id":"https://openalex.org/I4210110056","display_name":"Administra\u00e7\u00e3o Regional de Sa\u00fade de Lisboa e Vale do Tejo","ror":"https://ror.org/0208sdr22","country_code":"PT","type":"government","lineage":["https://openalex.org/I4210110056"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Joana Coelho Santos","raw_affiliation_strings":["Department of Child and Adolescent Psychiatry, Local Health Unit of Western Lisbon, Lisbon, PRT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Child and Adolescent Psychiatry, Local Health Unit of Western Lisbon, Lisbon, PRT","institution_ids":["https://openalex.org/I4210110056"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088324813","display_name":"Daniela Couto","orcid":"https://orcid.org/0009-0002-0118-1061","observed_orcids":["https://orcid.org/0009-0002-0118-1061","https://orcid.org/0000-0001-6643-5136"]},"institutions":[{"id":"https://openalex.org/I4210110056","display_name":"Administra\u00e7\u00e3o Regional de Sa\u00fade de Lisboa e Vale do Tejo","ror":"https://ror.org/0208sdr22","country_code":"PT","type":"government","lineage":["https://openalex.org/I4210110056"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Daniela Couto","raw_affiliation_strings":["Department of Child and Adolescent Psychiatry, Local Health Unit of Western Lisbon, Lisbon, PRT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Child and Adolescent Psychiatry, Local Health Unit of Western Lisbon, Lisbon, PRT","institution_ids":["https://openalex.org/I4210110056"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5076344852"],"corresponding_institution_ids":["https://openalex.org/I4210110056"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"17","issue":"4","first_page":"e82280","last_page":"e82280"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.3944999873638153,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.3944999873638153,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10182","display_name":"Child and Adolescent Psychosocial and Emotional Development","score":0.24779999256134033,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":0.21040000021457672,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/selective-mutism","display_name":"selective mutism","score":0.9980000257492065},{"id":"https://openalex.org/keywords/autism-spectrum-disorder","display_name":"autism spectrum disorder","score":0.9049999713897705},{"id":"https://openalex.org/keywords/puberty","display_name":"puberty","score":0.7680000066757202},{"id":"https://openalex.org/keywords/adolescent-anxiety","display_name":"adolescent anxiety","score":0.796999990940094},{"id":"https://openalex.org/keywords/transition-to-school","display_name":"transition to school","score":0.8149999976158142},{"id":"https://openalex.org/keywords/relocation","display_name":"relocation","score":0.703000009059906},{"id":"https://openalex.org/keywords/cognitive-behavioral-therapy","display_name":"cognitive behavioral therapy","score":0.8999999761581421},{"id":"https://openalex.org/keywords/fluoxetine","display_name":"fluoxetine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/pregabalin","display_name":"pregabalin","score":1.0},{"id":"https://openalex.org/keywords/multimodal-treatment","display_name":"multimodal therapy","score":0.8259999752044678},{"id":"https://openalex.org/keywords/treatment-resistant-anxiety","display_name":"treatment-resistant anxiety","score":0.5189999938011169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9407511353492737},{"id":"https://openalex.org/C2778538070","wikidata":"https://www.wikidata.org/wiki/Q1436063","display_name":"Autism spectrum disorder","level":3,"score":0.811150074005127},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.5158275961875916},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5108277797698975},{"id":"https://openalex.org/C2777154362","wikidata":"https://www.wikidata.org/wiki/Q7575316","display_name":"Spectrum disorder","level":2,"score":0.502760648727417},{"id":"https://openalex.org/C205778803","wikidata":"https://www.wikidata.org/wiki/Q38404","display_name":"Autism","level":2,"score":0.40186017751693726},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.38076233863830566}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.7759/cureus.82280","doi":"https://doi.org/10.7759/cureus.82280","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.82280","pdf_url":"https://assets.cureus.com/uploads/case_report/pdf/357742/20250415-198737-j9bit8.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},{"id":"pmid:40376346","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40376346","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Case Reports"},{"id":"pmh:oai:pubmedcentral.nih.gov:12079171","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12079171/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.7759/cureus.82280","doi":"https://doi.org/10.7759/cureus.82280","is_oa":true,"landing_page_url":"https://doi.org/10.7759/cureus.82280","pdf_url":"https://assets.cureus.com/uploads/case_report/pdf/357742/20250415-198737-j9bit8.pdf","source":{"id":"https://openalex.org/S2738950867","display_name":"Cureus","issn_l":"2168-8184","issn":["2168-8184"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","poland-20","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310316779","host_organization_name":"Cureus, Inc.","host_organization_lineage":["https://openalex.org/P4310316779"],"host_organization_lineage_names":["Cureus, Inc."],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cureus","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409463520.pdf","grobid_xml":"https://content.openalex.org/works/W4409463520.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W1913439650","https://openalex.org/W1973757724","https://openalex.org/W1977899807","https://openalex.org/W1997684900","https://openalex.org/W2035822457","https://openalex.org/W2036329341","https://openalex.org/W2041877758","https://openalex.org/W2049154361","https://openalex.org/W2050818564","https://openalex.org/W2073231072","https://openalex.org/W2094853561","https://openalex.org/W2132270420","https://openalex.org/W2410696340","https://openalex.org/W2802701653","https://openalex.org/W3124823677","https://openalex.org/W4206140259","https://openalex.org/W4210623514","https://openalex.org/W4281687410","https://openalex.org/W4319792447"],"related_works":["https://openalex.org/W4290635522","https://openalex.org/W4412809515","https://openalex.org/W2322997326","https://openalex.org/W7167358327","https://openalex.org/W4407617928","https://openalex.org/W2133408851","https://openalex.org/W2802701653","https://openalex.org/W4362014280","https://openalex.org/W2333423636","https://openalex.org/W2009247148"],"abstract_inverted_index":{"Selective":[0],"mutism":[1],"(SM)":[2],"is":[3,14,41,59],"a":[4,17,72],"rare":[5],"anxiety":[6,57,134],"disorder":[7,68],"typically":[8],"diagnosed":[9,98],"in":[10,22,32,63,121,136,162],"early":[11],"childhood.":[12],"It":[13,150],"characterized":[15],"by":[16],"persistent":[18],"failure":[19],"to":[20,30,113,167],"speak":[21],"specific":[23],"social":[24,124],"situations":[25],"despite":[26],"having":[27],"the":[28,35,82,129,142,156],"ability":[29],"verbalize":[31],"others.":[33],"Although":[34],"onset":[36,83],"of":[37,56,74,84,116,131,144,159],"SM":[38,80,117],"during":[39,45],"adolescence":[40],"uncommon,":[42],"its":[43],"emergence":[44],"puberty":[46,85],"or":[47],"major":[48],"life":[49],"transitions":[50],"may":[51],"reflect":[52],"an":[53,75],"atypical":[54,133],"form":[55],"that":[58],"more":[60],"frequently":[61],"observed":[62],"individuals":[64],"with":[65,99,138,164],"autism":[66],"spectrum":[67],"(ASD).":[69],"We":[70],"describe":[71],"case":[73,127],"11-year-old":[76],"girl":[77],"who":[78],"developed":[79],"following":[81],"and":[86,93,110,118,123,140,147],"significant":[87],"environmental":[88],"changes,":[89],"including":[90],"school":[91],"transition":[92],"relocation.":[94],"She":[95],"was":[96],"subsequently":[97],"ASD.":[100],"A":[101],"multidisciplinary":[102],"treatment":[103],"approach":[104],"involving":[105],"cognitive":[106],"behavioral":[107],"therapy,":[108],"fluoxetine,":[109],"pregabalin":[111],"led":[112],"complete":[114],"remission":[115],"marked":[119],"improvements":[120],"academic":[122],"functioning.":[125],"This":[126],"underscores":[128],"importance":[130],"recognising":[132],"presentations":[135],"adolescents":[137],"ASD":[139],"highlights":[141],"value":[143],"early,":[145],"individualized,":[146],"multimodal":[148],"interventions.":[149],"also":[151],"raises":[152],"ethical":[153],"considerations":[154],"regarding":[155],"temporary":[157],"use":[158],"covert":[160],"medication":[161],"cases":[163],"severe":[165],"resistance":[166],"treatment.":[168]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-04-16T00:00:00"}