{"id":"https://openalex.org/W4409450888","doi":"https://doi.org/10.1016/j.microc.2025.113659","title":"Strategies for the development and optimization of green acetonitrile-free HPLC methods for application in pharmaceutical analysis","display_name":"Strategies for the development and optimization of green acetonitrile-free HPLC methods for application in pharmaceutical analysis","publication_year":2025,"publication_date":"2025-04-15","ids":{"openalex":"https://openalex.org/W4409450888","doi":"https://doi.org/10.1016/j.microc.2025.113659"},"language":"en","primary_location":{"id":"doi:10.1016/j.microc.2025.113659","doi":"https://doi.org/10.1016/j.microc.2025.113659","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.microc.2025.113659","pdf_url":null,"source":{"id":"https://openalex.org/S151030190","display_name":"Microchemical Journal","issn_l":"0026-265X","issn":["0026-265X","1095-9149"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microchemical Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2139/ssrn.5137011","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Gabriela Lemos Ribeiro de Souza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136482","display_name":"Federal Center for Technological Education of Minas Gerais","ror":"https://ror.org/04ch49185","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210136482"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Gabriela Lemos Ribeiro de Souza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018886507","display_name":"A. Oliveira","orcid":"https://orcid.org/0009-0005-8576-1347","observed_orcids":["https://orcid.org/0009-0005-8576-1347"]},"institutions":[{"id":"https://openalex.org/I4210136482","display_name":"Federal Center for Technological Education of Minas Gerais","ror":"https://ror.org/04ch49185","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210136482"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Amanda de Paula Oliveira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063309402","display_name":"Paulo Salles Neto","orcid":"https://orcid.org/0009-0003-2842-1069","observed_orcids":["https://orcid.org/0009-0003-2842-1069"]},"institutions":[{"id":"https://openalex.org/I4210136482","display_name":"Federal Center for Technological Education of Minas Gerais","ror":"https://ror.org/04ch49185","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210136482"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Paulo Salles Neto","raw_affiliation_strings":["Department of Chemistry, Centro Federal de Educa\u00e7\u00e3o Tecnol\u00f3gica de Minas Gerais, Av. Amazonas 5253, 30421-169 BH-MG, Brazil"],"raw_orcid":"https://orcid.org/0009-0003-2842-1069","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Centro Federal de Educa\u00e7\u00e3o Tecnol\u00f3gica de Minas Gerais, Av. Amazonas 5253, 30421-169 BH-MG, Brazil","institution_ids":["https://openalex.org/I4210136482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026881983","display_name":"Jhonatan Bispo de Oliveira","orcid":"https://orcid.org/0000-0001-7329-8395","observed_orcids":["https://orcid.org/0000-0001-7329-8395"]},"institutions":[{"id":"https://openalex.org/I110200422","display_name":"Universidade Federal de Minas Gerais","ror":"https://ror.org/0176yjw32","country_code":"BR","type":"education","lineage":["https://openalex.org/I110200422"]},{"id":"https://openalex.org/I4210136482","display_name":"Federal Center for Technological Education of Minas Gerais","ror":"https://ror.org/04ch49185","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210136482"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Jhonatan Bispo de Oliveira","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029302451","display_name":"Cassiano Lino dos Santos Costa","orcid":"https://orcid.org/0000-0002-5937-9719","observed_orcids":["https://orcid.org/0000-0002-5937-9719"]},"institutions":[{"id":"https://openalex.org/I4210089139","display_name":"Centro de Desenvolvimento da Tecnologia Nuclear","ror":"https://ror.org/005e8tf31","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210089139","https://openalex.org/I4210151455","https://openalex.org/I76248293"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cassiano Lino dos Santos Costa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000794907","display_name":"Patterson P. de Souza","orcid":"https://orcid.org/0000-0002-1907-5876","observed_orcids":["https://orcid.org/0000-0002-1907-5876"]},"institutions":[{"id":"https://openalex.org/I4210136482","display_name":"Federal Center for Technological Education of Minas Gerais","ror":"https://ror.org/04ch49185","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210136482"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Patterson Patricio de Souza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062416169","display_name":"Marina Bicalho Silveira","orcid":"https://orcid.org/0000-0002-7860-4416","observed_orcids":["https://orcid.org/0000-0002-7860-4416"]},"institutions":[{"id":"https://openalex.org/I4210089139","display_name":"Centro de Desenvolvimento da Tecnologia Nuclear","ror":"https://ror.org/005e8tf31","country_code":"BR","type":"facility","lineage":["https://openalex.org/I4210089139","https://openalex.org/I4210151455","https://openalex.org/I76248293"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marina Bicalho Silveira","raw_affiliation_strings":["Centro de Desenvolvimento da Tecnologia Nuclear, CDTN, 31270-901 Belo Horizonte, MG, Brazil"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Desenvolvimento da Tecnologia Nuclear, CDTN, 31270-901 Belo Horizonte, MG, Brazil","institution_ids":["https://openalex.org/I4210089139"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058438958","display_name":"Ildefonso Binatti","orcid":"https://orcid.org/0000-0002-0454-0026","observed_orcids":["https://orcid.org/0000-0002-0454-0026"]},"institutions":[{"id":"https://openalex.org/I4210136482","display_name":"Federal Center for Technological Education of Minas Gerais","ror":"https://ror.org/04ch49185","country_code":"BR","type":"education","lineage":["https://openalex.org/I4210136482"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Ildefonso Binatti","raw_affiliation_strings":["Department of Chemistry, Centro Federal de Educa\u00e7\u00e3o Tecnol\u00f3gica de Minas Gerais, Av. Amazonas 5253, 30421-169 BH-MG, Brazil"],"raw_orcid":"https://orcid.org/0000-0002-0454-0026","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Centro Federal de Educa\u00e7\u00e3o Tecnol\u00f3gica de Minas Gerais, Av. Amazonas 5253, 30421-169 BH-MG, Brazil","institution_ids":["https://openalex.org/I4210136482"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5058438958"],"corresponding_institution_ids":["https://openalex.org/I4210136482"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":null,"fwci":2.2852,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.86778384,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"213","issue":null,"first_page":"113659","last_page":"113659"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.98580002784729,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13180","display_name":"Chemistry and Chemical Engineering","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2304","display_name":"Environmental Chemistry"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/green-chemistry","display_name":"green chemistry","score":0.6980000138282776},{"id":"https://openalex.org/keywords/methanol","display_name":"methanol","score":0.41600000858306885},{"id":"https://openalex.org/keywords/trifluoroacetic-acid","display_name":"trifluoroacetic acid","score":0.9980000257492065},{"id":"https://openalex.org/keywords/purity-determination","display_name":"purity determination","score":0.7110000252723694},{"id":"https://openalex.org/keywords/method-optimization","display_name":"method optimization","score":0.7400000095367432},{"id":"https://openalex.org/keywords/multivariate-experimental-design","display_name":"multivariate experimental design","score":0.8610000014305115},{"id":"https://openalex.org/keywords/pharmaceutical-quality-control","display_name":"pharmaceutical quality control","score":0.7260000109672546},{"id":"https://openalex.org/keywords/active-pharmaceutical-ingredients","display_name":"active pharmaceutical ingredients","score":0.5590000152587891}],"concepts":[{"id":"https://openalex.org/C2777463227","wikidata":"https://www.wikidata.org/wiki/Q408047","display_name":"Acetonitrile","level":2,"score":0.6716089844703674},{"id":"https://openalex.org/C179998833","wikidata":"https://www.wikidata.org/wiki/Q381233","display_name":"High-performance liquid chromatography","level":2,"score":0.5745080709457397},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5257657170295715},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5011987686157227},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.4288768172264099},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10966011881828308}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.microc.2025.113659","doi":"https://doi.org/10.1016/j.microc.2025.113659","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.microc.2025.113659","pdf_url":null,"source":{"id":"https://openalex.org/S151030190","display_name":"Microchemical Journal","issn_l":"0026-265X","issn":["0026-265X","1095-9149"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microchemical Journal","raw_type":"journal-article"},{"id":"doi:10.2139/ssrn.5137011","doi":"https://doi.org/10.2139/ssrn.5137011","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.5137011","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.2139/ssrn.5137011","doi":"https://doi.org/10.2139/ssrn.5137011","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.5137011","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Responsible consumption and production","id":"https://metadata.un.org/sdg/12","score":0.6000000238418579}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F2408532542","display_name":"Centro Federal de Educa\u00e7\u00e3o Tecnol\u00f3gica de Minas Gerais","ror":"https://ror.org/04ch49185"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322980","display_name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de Minas Gerais","ror":"https://ror.org/00nc55f03"},{"id":"https://openalex.org/F4320329974","display_name":"Centro de Desenvolvimento da Tecnologia Nuclear","ror":"https://ror.org/005e8tf31"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":40,"referenced_works":["https://openalex.org/W184829647","https://openalex.org/W1914274384","https://openalex.org/W1965842695","https://openalex.org/W1971343411","https://openalex.org/W1996842820","https://openalex.org/W1998251871","https://openalex.org/W2000397268","https://openalex.org/W2010698417","https://openalex.org/W2023761565","https://openalex.org/W2036424009","https://openalex.org/W2045983991","https://openalex.org/W2066283531","https://openalex.org/W2076393768","https://openalex.org/W2083094358","https://openalex.org/W2083440329","https://openalex.org/W2089783309","https://openalex.org/W2094416377","https://openalex.org/W2119343809","https://openalex.org/W2141066200","https://openalex.org/W2147203423","https://openalex.org/W2150324167","https://openalex.org/W2167209294","https://openalex.org/W2270996183","https://openalex.org/W2541665535","https://openalex.org/W2578127432","https://openalex.org/W2611505834","https://openalex.org/W2747562896","https://openalex.org/W2797993151","https://openalex.org/W2799749496","https://openalex.org/W2908336004","https://openalex.org/W2914832741","https://openalex.org/W2970329223","https://openalex.org/W3019635787","https://openalex.org/W3089427151","https://openalex.org/W3179520431","https://openalex.org/W3207933610","https://openalex.org/W4307898122","https://openalex.org/W4317358722","https://openalex.org/W4367359813","https://openalex.org/W4396620292"],"related_works":["https://openalex.org/W7222289819","https://openalex.org/W4320915807","https://openalex.org/W4412902410","https://openalex.org/W4375833945","https://openalex.org/W3023429511","https://openalex.org/W2799749496","https://openalex.org/W7160424578","https://openalex.org/W4411463100","https://openalex.org/W7167100355","https://openalex.org/W4415358312"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-04-15T00:00:00"}
