{"id":"https://openalex.org/W4409414457","doi":"https://doi.org/10.1038/s41467-025-58767-6","title":"Inactivation of GH3.5 by COP1-mediated K63-linked ubiquitination promotes seedling hypocotyl elongation","display_name":"Inactivation of GH3.5 by COP1-mediated K63-linked ubiquitination promotes seedling hypocotyl elongation","publication_year":2025,"publication_date":"2025-04-14","ids":{"openalex":"https://openalex.org/W4409414457","doi":"https://doi.org/10.1038/s41467-025-58767-6","pmid":"https://pubmed.ncbi.nlm.nih.gov/40229271","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11997217"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-025-58767-6","doi":"https://doi.org/10.1038/s41467-025-58767-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-025-58767-6","pdf_url":"https://www.nature.com/articles/s41467-025-58767-6.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-025-58767-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043878973","display_name":"Yongting Liu","orcid":"https://orcid.org/0009-0002-6773-6074","observed_orcids":["https://orcid.org/0009-0002-6773-6074"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yongting Liu","raw_affiliation_strings":["Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China","State Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China","institution_ids":["https://openalex.org/I3045169105"]},{"raw_affiliation_string":"State Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, China","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072700228","display_name":"Yinpeng Xie","orcid":"https://orcid.org/0000-0002-4897-9612","observed_orcids":["https://orcid.org/0000-0002-4897-9612"]},"institutions":[{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yinpeng Xie","raw_affiliation_strings":["Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China","State Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling, Shaanxi, China"],"raw_orcid":"https://orcid.org/0000-0002-4897-9612","affiliations":[{"raw_affiliation_string":"Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China","institution_ids":["https://openalex.org/I3045169105"]},{"raw_affiliation_string":"State Key Laboratory of Crop Stress Biology for Arid Areas/Shaanxi Key Laboratory of Apple, College of Horticulture, Northwest A&F University, Yangling, Shaanxi, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071135241","display_name":"Dongqing Xu","orcid":"https://orcid.org/0000-0002-7498-6568","observed_orcids":["https://orcid.org/0000-0002-7498-6568"]},"institutions":[{"id":"https://openalex.org/I119454577","display_name":"Nanjing Agricultural University","ror":"https://ror.org/05td3s095","country_code":"CN","type":"education","lineage":["https://openalex.org/I119454577"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongqing Xu","raw_affiliation_strings":["State Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, National Center for Soybean Improvement, College of Agriculture, Nanjing Agricultural University, Nanjing, China"],"raw_orcid":"https://orcid.org/0000-0002-7498-6568","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Crop Genetics & Germplasm Enhancement and Utilization, National Center for Soybean Improvement, College of Agriculture, Nanjing Agricultural University, Nanjing, China","institution_ids":["https://openalex.org/I119454577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000068635","display_name":"Xing Wang Deng","orcid":"https://orcid.org/0000-0001-8709-1467","observed_orcids":["https://orcid.org/0000-0001-8709-1467","https://orcid.org/0000-0003-0590-8993"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I3045169105","display_name":"Southern University of Science and Technology","ror":"https://ror.org/049tv2d57","country_code":"CN","type":"education","lineage":["https://openalex.org/I3045169105"]},{"id":"https://openalex.org/I4210160507","display_name":"Center for Life Sciences","ror":"https://ror.org/05kje8j93","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570","https://openalex.org/I4210160507","https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xing Wang Deng","raw_affiliation_strings":["Peking-Tsinghua Center for Life Sciences, School of Advanced Agricultural Sciences, Peking University, Beijing, China. deng@pku.edu.cn","Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China. deng@pku.edu.cn","State Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, China. deng@pku.edu.cn"],"raw_orcid":"https://orcid.org/0000-0001-8709-1467","affiliations":[{"raw_affiliation_string":"Peking-Tsinghua Center for Life Sciences, School of Advanced Agricultural Sciences, Peking University, Beijing, China. deng@pku.edu.cn","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210160507"]},{"raw_affiliation_string":"Shenzhen Key Laboratory of Plant Genetic Engineering and Molecular Design, Institute of Plant and Food Science, Department of Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen, China. deng@pku.edu.cn","institution_ids":["https://openalex.org/I3045169105"]},{"raw_affiliation_string":"State Key Laboratory of Wheat Improvement, Peking University Institute of Advanced Agricultural Sciences, Shandong Laboratory of Advanced Agricultural Sciences in Weifang, Weifang, Shandong, China. deng@pku.edu.cn","institution_ids":["https://openalex.org/I20231570"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101572754","display_name":"Jian Li","orcid":"https://orcid.org/0000-0002-1287-8932","observed_orcids":["https://orcid.org/0000-0002-1287-8932"]},"institutions":[{"id":"https://openalex.org/I152031979","display_name":"Nanjing Normal University","ror":"https://ror.org/036trcv74","country_code":"CN","type":"education","lineage":["https://openalex.org/I152031979"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jian Li","raw_affiliation_strings":["College of Life Sciences, Nanjing Normal University, Nanjing, China. jian@njnu.edu.cn"],"raw_orcid":"https://orcid.org/0000-0002-1287-8932","affiliations":[{"raw_affiliation_string":"College of Life Sciences, Nanjing Normal University, Nanjing, China. jian@njnu.edu.cn","institution_ids":["https://openalex.org/I152031979"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5000068635","https://openalex.org/A5101572754"],"corresponding_institution_ids":["https://openalex.org/I152031979","https://openalex.org/I20231570","https://openalex.org/I3045169105","https://openalex.org/I4210160507"],"apc_list":{"value":6990,"currency":"USD","value_usd":6990},"apc_paid":{"value":6990,"currency":"USD","value_usd":6990},"fwci":8.9624,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.98596078,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"16","issue":"1","first_page":"3541","last_page":"3541"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10184","display_name":"Plant Molecular Biology Research","score":0.02459999918937683,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12475","display_name":"Plant Parasitism and Resistance","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cop1","display_name":"COP1","score":0.9929999709129333},{"id":"https://openalex.org/keywords/k63-linked-ubiquitination","display_name":"K63-linked ubiquitination","score":0.8379999995231628},{"id":"https://openalex.org/keywords/indole-3-acetic-acid","display_name":"indole-3-acetic acid","score":0.8500000238418579},{"id":"https://openalex.org/keywords/auxin-metabolism","display_name":"auxin metabolism","score":0.9190000295639038},{"id":"https://openalex.org/keywords/hypocotyl-elongation","display_name":"hypocotyl elongation","score":0.8569999933242798},{"id":"https://openalex.org/keywords/photomorphogenesis","display_name":"photomorphogenesis","score":0.8420000076293945},{"id":"https://openalex.org/keywords/light-regulation","display_name":"light regulation","score":0.4659999907016754},{"id":"https://openalex.org/keywords/amino-acid-conjugation","display_name":"amino acid conjugation","score":0.640999972820282},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.8709999918937683}],"concepts":[{"id":"https://openalex.org/C2781446133","wikidata":"https://www.wikidata.org/wiki/Q1935099","display_name":"Photomorphogenesis","level":5,"score":0.8753867149353027},{"id":"https://openalex.org/C105409712","wikidata":"https://www.wikidata.org/wiki/Q1426202","display_name":"Hypocotyl","level":2,"score":0.81279057264328},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.7985791563987732},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.7937648892402649},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5593805313110352},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5003612041473389},{"id":"https://openalex.org/C134459356","wikidata":"https://www.wikidata.org/wiki/Q4274835","display_name":"Ubiquitin ligase","level":4,"score":0.49918222427368164},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.47887012362480164},{"id":"https://openalex.org/C158448853","wikidata":"https://www.wikidata.org/wiki/Q425218","display_name":"Repressor","level":4,"score":0.4562869668006897},{"id":"https://openalex.org/C33947775","wikidata":"https://www.wikidata.org/wiki/Q271439","display_name":"Elongation","level":3,"score":0.4262978136539459},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.11617031693458557},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.11462229490280151},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.11367642879486084},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07259836792945862},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C112950240","wikidata":"https://www.wikidata.org/wiki/Q76005","display_name":"Ultimate tensile strength","level":2,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D007210","descriptor_name":"Indoleacetic Acids","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008027","descriptor_name":"Light","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008239","descriptor_name":"Lysine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018506","descriptor_name":"Gene Expression Regulation, Plant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018546","descriptor_name":"Hypocotyl","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018546","descriptor_name":"Hypocotyl","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D018546","descriptor_name":"Hypocotyl","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D036226","descriptor_name":"Seedlings","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D036226","descriptor_name":"Seedlings","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":true},{"descriptor_ui":"D036226","descriptor_name":"Seedlings","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D044767","descriptor_name":"Ubiquitin-Protein Ligases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D054875","descriptor_name":"Ubiquitination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":6,"locations":[{"id":"doi:10.1038/s41467-025-58767-6","doi":"https://doi.org/10.1038/s41467-025-58767-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-025-58767-6","pdf_url":"https://www.nature.com/articles/s41467-025-58767-6.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:10809224","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11997217","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:40229271","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40229271","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11997217","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11997217/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmh:oai:RePEc:nat:natcom:v:16:y:2025:i:1:d:10.1038_s41467-025-58767-6","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-025-58767-6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:1291d05243534e17adcfd7620f41b3c4","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/1291d05243534e17adcfd7620f41b3c4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 16, Iss 1, Pp 1-15 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41467-025-58767-6","doi":"https://doi.org/10.1038/s41467-025-58767-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-025-58767-6","pdf_url":"https://www.nature.com/articles/s41467-025-58767-6.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1841795244","display_name":null,"funder_award_id":"32200198","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391452596","display_name":null,"funder_award_id":"ZR2021ZD30","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G6594265706","display_name":null,"funder_award_id":"Y01226026","funder_id":"https://openalex.org/F4320327605","funder_display_name":"Southern University of Science and Technology"},{"id":"https://openalex.org/G8866624709","display_name":null,"funder_award_id":"SYS202206","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"}],"funders":[{"id":"https://openalex.org/F4320310931","display_name":"Capital Normal University","ror":"https://ror.org/005edt527"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321131","display_name":"China Agricultural University","ror":"https://ror.org/04v3ywz14"},{"id":"https://openalex.org/F4320324174","display_name":"Natural Science Foundation of Shandong Province","ror":null},{"id":"https://openalex.org/F4320324731","display_name":"Yunnan University","ror":"https://ror.org/0040axw97"},{"id":"https://openalex.org/F4320324775","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294"},{"id":"https://openalex.org/F4320327518","display_name":"Priority Academic Program Development of Jiangsu Higher Education Institutions","ror":null},{"id":"https://openalex.org/F4320327605","display_name":"Southern University of Science and Technology","ror":null},{"id":"https://openalex.org/F4320332603","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409414457.pdf","grobid_xml":"https://content.openalex.org/works/W4409414457.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W1665182114","https://openalex.org/W1892406518","https://openalex.org/W1937054661","https://openalex.org/W1965193486","https://openalex.org/W1967467650","https://openalex.org/W1989001617","https://openalex.org/W1991117200","https://openalex.org/W2002821316","https://openalex.org/W2005572311","https://openalex.org/W2006153112","https://openalex.org/W2018051749","https://openalex.org/W2019364309","https://openalex.org/W2028157992","https://openalex.org/W2052821301","https://openalex.org/W2057926548","https://openalex.org/W2084390827","https://openalex.org/W2092411377","https://openalex.org/W2099849055","https://openalex.org/W2100651643","https://openalex.org/W2101066284","https://openalex.org/W2101811213","https://openalex.org/W2102569081","https://openalex.org/W2109354542","https://openalex.org/W2110311890","https://openalex.org/W2110591857","https://openalex.org/W2114194370","https://openalex.org/W2116670637","https://openalex.org/W2123263831","https://openalex.org/W2131396344","https://openalex.org/W2134030532","https://openalex.org/W2135339359","https://openalex.org/W2136136435","https://openalex.org/W2152793376","https://openalex.org/W2157909952","https://openalex.org/W2158215557","https://openalex.org/W2158217826","https://openalex.org/W2162665548","https://openalex.org/W2164185725","https://openalex.org/W2171914198","https://openalex.org/W2225308925","https://openalex.org/W2345069008","https://openalex.org/W2530977520","https://openalex.org/W2549415262","https://openalex.org/W2603395851","https://openalex.org/W2622560248","https://openalex.org/W2775574987","https://openalex.org/W2783088162","https://openalex.org/W2788004032","https://openalex.org/W2794197059","https://openalex.org/W2932716017","https://openalex.org/W2937445158","https://openalex.org/W2986153361","https://openalex.org/W2995405112","https://openalex.org/W3009097360","https://openalex.org/W3009288282","https://openalex.org/W3016207241","https://openalex.org/W3099457548","https://openalex.org/W3119483631","https://openalex.org/W3120997367","https://openalex.org/W3215186811","https://openalex.org/W3215915240","https://openalex.org/W3216752034","https://openalex.org/W4200452190","https://openalex.org/W4210284048","https://openalex.org/W4214621942","https://openalex.org/W4220762243","https://openalex.org/W4224245990","https://openalex.org/W4282938832","https://openalex.org/W4283735655","https://openalex.org/W4310493719","https://openalex.org/W4319656937","https://openalex.org/W4320921234","https://openalex.org/W4322733110","https://openalex.org/W4379598112","https://openalex.org/W4389068531","https://openalex.org/W4396515363","https://openalex.org/W4399245361","https://openalex.org/W4400337638"],"related_works":["https://openalex.org/W2602295289","https://openalex.org/W7223170565","https://openalex.org/W2798987124","https://openalex.org/W4396515363","https://openalex.org/W2009072316","https://openalex.org/W2011265440","https://openalex.org/W7047840748","https://openalex.org/W2096253627","https://openalex.org/W2766645333","https://openalex.org/W2165450577"],"abstract_inverted_index":{"CONSTITUTIVELY":[0],"PHOTOMORPHOGENIC":[1],"1":[2],"(COP1),":[3],"which":[4,154],"was":[5],"first":[6],"discovered":[7],"as":[8],"a":[9,58],"central":[10],"repressor":[11],"of":[12,53,113,129,134,147],"photomorphogenesis":[13],"in":[14,20,72,106],"Arabidopsis,":[15],"destabilizes":[16],"proteins":[17],"by":[18,124,153],"ubiquitination":[19,36,105,149],"both":[21],"plants":[22],"and":[23,30,82,136,150],"animals.":[24],"However,":[25],"it":[26,99],"is":[27],"unclear":[28],"whether":[29],"how":[31],"Arabidopsis":[32],"COP1":[33,78,91,130],"mediates":[34],"non-proteolytic":[35,145],"to":[37,64,87,115,159],"regulate":[38],"photomorphogenesis.":[39],"Here,":[40],"we":[41],"show":[42,76],"that":[43,60,77],"COP1-mediated":[44,148],"lysine":[45],"63":[46],"(K63)-linked":[47],"polyubiquitination":[48],"inhibits":[49],"the":[50,73,107,110,126,132,144,151],"enzyme":[51],"activity":[52,102],"GRETCHEN":[54],"HAGEN":[55],"3.5":[56],"(GH3.5),":[57],"synthetase":[59],"conjugates":[61],"amino":[62],"acids":[63],"indole-3-acetic":[65],"acid":[66,117],"(IAA),":[67],"thereby":[68],"promoting":[69],"hypocotyl":[70,89,161],"elongation":[71],"dark.":[74],"We":[75],"physically":[79],"interacts":[80],"with":[81],"genetically":[83],"acts":[84],"through":[85,103],"GH3.5":[86,95,101,135],"promote":[88],"elongation.":[90,162],"does":[92],"not":[93],"affect":[94],"protein":[96],"stability;":[97],"however,":[98],"suppresses":[100],"K63-linked":[104],"dark,":[108],"inhibiting":[109],"endogenous":[111],"conversion":[112],"IAA":[114,122],"IAA-amino":[116],"conjugates.":[118],"Further,":[119],"light":[120,142,155],"regulates":[121,156],"metabolism":[123,158],"suppressing":[125],"inhibitory":[127],"effect":[128],"on":[131,143],"function":[133],"its":[137],"homologs.":[138],"Our":[139],"results":[140],"shed":[141],"role":[146],"mechanism":[152],"auxin":[157],"modulate":[160]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":9}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2025-04-14T00:00:00"}