{"id":"https://openalex.org/W4409414325","doi":"https://doi.org/10.1159/000543616","title":"Nutrition for Preconception Health and Fertility","display_name":"Nutrition for Preconception Health and Fertility","publication_year":2025,"publication_date":"2025-04-14","ids":{"openalex":"https://openalex.org/W4409414325","doi":"https://doi.org/10.1159/000543616","pmid":"https://pubmed.ncbi.nlm.nih.gov/40228488"},"language":"en","primary_location":{"id":"doi:10.1159/000543616","doi":"https://doi.org/10.1159/000543616","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000543616","pdf_url":null,"source":{"id":"https://openalex.org/S153227239","display_name":"Annals of Nutrition and Metabolism","issn_l":"0250-6807","issn":["0250-6807","1421-9697"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Nutrition and Metabolism","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5058924208","display_name":"Linden Jane Stocker","orcid":"https://orcid.org/0000-0002-0930-1673","observed_orcids":["https://orcid.org/0000-0002-0930-1673"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Linden Stocker","raw_affiliation_strings":["Department of Obstetrics, Southampton University Hospitals NHS Foundation Trust, Southampton, UK","School of Human Development and Health, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Southampton University Hospitals NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]},{"raw_affiliation_string":"School of Human Development and Health, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085590104","display_name":"Alexandra Kermack","orcid":"https://orcid.org/0000-0002-9176-9426","observed_orcids":["https://orcid.org/0000-0002-9176-9426"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Alexandra Kermack","raw_affiliation_strings":["Department of Obstetrics, Southampton University Hospitals NHS Foundation Trust, Southampton, UK, a.kermack@surrey.ac.uk","Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK, a.kermack@surrey.ac.uk","Department of Obstetrics, Southampton University Hospitals NHS Foundation Trust, Southampton, UK","Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Southampton University Hospitals NHS Foundation Trust, Southampton, UK, a.kermack@surrey.ac.uk","institution_ids":["https://openalex.org/I2802965805"]},{"raw_affiliation_string":"Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK, a.kermack@surrey.ac.uk","institution_ids":["https://openalex.org/I28290843"]},{"raw_affiliation_string":"Department of Obstetrics, Southampton University Hospitals NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805"]},{"raw_affiliation_string":"Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031184713","display_name":"Keith M. Godfrey","orcid":"https://orcid.org/0000-0002-4643-0618","observed_orcids":["https://orcid.org/0000-0002-4643-0618"]},"institutions":[{"id":"https://openalex.org/I2802965805","display_name":"University Hospital Southampton NHS Foundation Trust","ror":"https://ror.org/0485axj58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802965805"]},{"id":"https://openalex.org/I4210118229","display_name":"NIHR Southampton Biomedical Research Centre","ror":"https://ror.org/01qqpzg67","country_code":"GB","type":"facility","lineage":["https://openalex.org/I2802965805","https://openalex.org/I4210118229","https://openalex.org/I43439940"]},{"id":"https://openalex.org/I4210148293","display_name":"MRC Lifecourse Epidemiology Unit","ror":"https://ror.org/04j4a6x59","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210087105","https://openalex.org/I4210148293","https://openalex.org/I43439940","https://openalex.org/I90344618"]},{"id":"https://openalex.org/I43439940","display_name":"University of Southampton","ror":"https://ror.org/01ryk1543","country_code":"GB","type":"education","lineage":["https://openalex.org/I43439940"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Keith Godfrey","raw_affiliation_strings":["MRC Lifecourse Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton, and University Hospital Southampton NHS Foundation Trust, Southampton, UK","School of Human Development and Health, University of Southampton, Southampton, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MRC Lifecourse Epidemiology Centre and NIHR Southampton Biomedical Research Centre, University of Southampton, and University Hospital Southampton NHS Foundation Trust, Southampton, UK","institution_ids":["https://openalex.org/I2802965805","https://openalex.org/I4210118229","https://openalex.org/I4210148293","https://openalex.org/I43439940"]},{"raw_affiliation_string":"School of Human Development and Health, University of Southampton, Southampton, UK","institution_ids":["https://openalex.org/I43439940"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.1373,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.22115869,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"81","issue":"Suppl. 3","first_page":"9","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.8227999806404114,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11156","display_name":"Reproductive Health and Technologies","score":0.8227999806404114,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10364","display_name":"Reproductive Biology and Fertility","score":0.04619999974966049,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10390","display_name":"Ovarian function and disorders","score":0.01810000091791153,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/preconception-care","display_name":"preconception care","score":0.9200000166893005},{"id":"https://openalex.org/keywords/fertility","display_name":"fertility","score":0.9330000281333923},{"id":"https://openalex.org/keywords/nutrition","display_name":"nutrition","score":0.7580000162124634},{"id":"https://openalex.org/keywords/macronutrients","display_name":"macronutrients","score":0.9810000061988831},{"id":"https://openalex.org/keywords/micronutrients","display_name":"micronutrients","score":1.0},{"id":"https://openalex.org/keywords/lifestyle","display_name":"lifestyle","score":0.6919999718666077},{"id":"https://openalex.org/keywords/alcohol","display_name":"alcohol","score":0.6019999980926514},{"id":"https://openalex.org/keywords/caffeine","display_name":"caffeine","score":0.9990000128746033},{"id":"https://openalex.org/keywords/body-mass-index","display_name":"body mass index","score":0.9990000128746033},{"id":"https://openalex.org/keywords/reproductive-health","display_name":"reproductive health","score":0.8510000109672546},{"id":"https://openalex.org/keywords/hormone-balance","display_name":"hormonal balance","score":0.6930000185966492},{"id":"https://openalex.org/keywords/gamete-development","display_name":"gamete development","score":0.9509999752044678},{"id":"https://openalex.org/keywords/implantation","display_name":"implantation","score":0.796999990940094},{"id":"https://openalex.org/keywords/pregnancy","display_name":"pregnancy","score":0.8149999976158142}],"concepts":[{"id":"https://openalex.org/C518429986","wikidata":"https://www.wikidata.org/wiki/Q964401","display_name":"Fertility","level":3,"score":0.7271686792373657},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5725178718566895},{"id":"https://openalex.org/C14522933","wikidata":"https://www.wikidata.org/wiki/Q531507","display_name":"Micronutrient","level":2,"score":0.5421631336212158},{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.5152297616004944},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5136739611625671},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.5042275190353394},{"id":"https://openalex.org/C138816342","wikidata":"https://www.wikidata.org/wiki/Q189603","display_name":"Public health","level":2,"score":0.4517858922481537},{"id":"https://openalex.org/C121752807","wikidata":"https://www.wikidata.org/wiki/Q1981388","display_name":"Reproductive health","level":3,"score":0.41679248213768005},{"id":"https://openalex.org/C74909509","wikidata":"https://www.wikidata.org/wiki/Q10387","display_name":"Gerontology","level":1,"score":0.4094220995903015},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.287533164024353},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.17106309533119202},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1400248110294342},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005298","descriptor_name":"Fertility","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008019","descriptor_name":"Life Style","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009752","descriptor_name":"Nutritional Status","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016742","descriptor_name":"Preconception Care","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D018977","descriptor_name":"Micronutrients","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D060728","descriptor_name":"Reproductive Health","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1159/000543616","doi":"https://doi.org/10.1159/000543616","is_oa":false,"landing_page_url":"https://doi.org/10.1159/000543616","pdf_url":null,"source":{"id":"https://openalex.org/S153227239","display_name":"Annals of Nutrition and Metabolism","issn_l":"0250-6807","issn":["0250-6807","1421-9697"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317820","host_organization_name":"Karger Publishers","host_organization_lineage":["https://openalex.org/P4310317820"],"host_organization_lineage_names":["Karger Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of Nutrition and Metabolism","raw_type":"journal-article"},{"id":"pmid:40228488","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40228488","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Annals of nutrition & metabolism","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.6735000014305115}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":91,"referenced_works":["https://openalex.org/W105550150","https://openalex.org/W1485812724","https://openalex.org/W1926957047","https://openalex.org/W1973379361","https://openalex.org/W1976296087","https://openalex.org/W1982403396","https://openalex.org/W1991626503","https://openalex.org/W1995632906","https://openalex.org/W2003726074","https://openalex.org/W2007653840","https://openalex.org/W2029381990","https://openalex.org/W2040460087","https://openalex.org/W2050075673","https://openalex.org/W2052999816","https://openalex.org/W2059638656","https://openalex.org/W2094620167","https://openalex.org/W2100409392","https://openalex.org/W2108154053","https://openalex.org/W2108664872","https://openalex.org/W2109533285","https://openalex.org/W2110475447","https://openalex.org/W2113690878","https://openalex.org/W2120921162","https://openalex.org/W2127382802","https://openalex.org/W2129763461","https://openalex.org/W2131093877","https://openalex.org/W2140112227","https://openalex.org/W2146257100","https://openalex.org/W2146644275","https://openalex.org/W2150147985","https://openalex.org/W2181159933","https://openalex.org/W2405624971","https://openalex.org/W2520168912","https://openalex.org/W2587300313","https://openalex.org/W2621846429","https://openalex.org/W2623852457","https://openalex.org/W2640267936","https://openalex.org/W2682414161","https://openalex.org/W2735499299","https://openalex.org/W2736873575","https://openalex.org/W2767104704","https://openalex.org/W2767888663","https://openalex.org/W2775313512","https://openalex.org/W2787759077","https://openalex.org/W2787931223","https://openalex.org/W2793981793","https://openalex.org/W2799988970","https://openalex.org/W2803915445","https://openalex.org/W2888057227","https://openalex.org/W2899197098","https://openalex.org/W2906003299","https://openalex.org/W2946201656","https://openalex.org/W2995453701","https://openalex.org/W3005041993","https://openalex.org/W3010668667","https://openalex.org/W3014900082","https://openalex.org/W3037023841","https://openalex.org/W3037894442","https://openalex.org/W3080085702","https://openalex.org/W3087986622","https://openalex.org/W3107793053","https://openalex.org/W3112491521","https://openalex.org/W3132713966","https://openalex.org/W3152357308","https://openalex.org/W3157171676","https://openalex.org/W3158329272","https://openalex.org/W3158397412","https://openalex.org/W3158959631","https://openalex.org/W3170472005","https://openalex.org/W3195314135","https://openalex.org/W3199454339","https://openalex.org/W4206272400","https://openalex.org/W4206779316","https://openalex.org/W4210693689","https://openalex.org/W4214576200","https://openalex.org/W4224252615","https://openalex.org/W4281742275","https://openalex.org/W4311053301","https://openalex.org/W4311504642","https://openalex.org/W4315928684","https://openalex.org/W4319321426","https://openalex.org/W4321523286","https://openalex.org/W4380050945","https://openalex.org/W4386000104","https://openalex.org/W4387164600","https://openalex.org/W4388744961","https://openalex.org/W4389334470","https://openalex.org/W4391316306","https://openalex.org/W4392240624","https://openalex.org/W4393975035","https://openalex.org/W4394015428"],"related_works":["https://openalex.org/W4245394136","https://openalex.org/W86152347","https://openalex.org/W7125696506","https://openalex.org/W4211111101","https://openalex.org/W2152960040","https://openalex.org/W6993198260","https://openalex.org/W4405847034","https://openalex.org/W2440458753","https://openalex.org/W2800419398","https://openalex.org/W1732010980"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,55],"importance":[2,45,128],"of":[3,11,18,26,36,46,52,104,114,126,129,132,160],"preconception":[4,106,133],"care":[5],"is":[6,100],"now":[7],"widely":[8],"recognised.":[9],"Optimisation":[10],"the":[12,16,24,34,37,44,50,66,102,112,127,130,166],"lifestyle,":[13],"nutrition,":[14],"and":[15,28,65,86,117,121,135,143],"health":[17,35],"a":[19,29,74],"couple":[20],"not":[21],"only":[22],"affects":[23],"chances":[25],"conception":[27],"successful":[30],"pregnancy":[31,144],"but":[32],"also":[33,72],"resulting":[38],"offspring.":[39],"Currently,":[40],"limited":[41],"data":[42],"reinforce":[43],"further":[47],"research":[48,99],"examining":[49,101],"role":[51,103],"individual":[53],"nutrients.":[54],"complex":[56],"interactions":[57],"that":[58],"these":[59],"nutrients":[60],"have":[61],"with":[62,158],"each":[63],"other":[64],"resultant":[67],"effect":[68,131],"on":[69,137],"fertility":[70,120],"should":[71,90,145],"be":[73,91,146],"focus":[75],"for":[76],"future":[77],"investigation.":[78],"Modifiable":[79],"risk":[80],"factors":[81],"such":[82],"as":[83,163,165],"alcohol,":[84],"caffeine,":[85],"body":[87],"mass":[88],"index":[89],"optimised":[92],"prior":[93],"to":[94,96,150],"attempting":[95],"conceive.":[97],"New":[98],"personalised":[105],"advice.":[107],"SUMMARY:":[108],"This":[109,148],"review":[110],"examines":[111],"roles":[113],"macronutrients,":[115],"micronutrients,":[116],"lifestyle":[118,136],"in":[119],"reproductive":[122],"health.":[123],"Raising":[124],"awareness":[125],"nutrition":[134],"hormone":[138],"balance,":[139],"gamete":[140],"development,":[141],"implantation,":[142],"paramount.":[147],"applies":[149],"all":[151],"healthcare":[152],"professionals":[153],"who":[154],"come":[155],"into":[156],"contact":[157],"people":[159],"child-bearing":[161],"age,":[162],"well":[164],"general":[167],"public.":[168]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-04-14T00:00:00"}
