{"id":"https://openalex.org/W4409411544","doi":"https://doi.org/10.61186/jbums.31.2.150","title":"The effects of liraglutide on the characteristics of blood parameters and testicular tissue induced diabetes and obesity in mice","display_name":"The effects of liraglutide on the characteristics of blood parameters and testicular tissue induced diabetes and obesity in mice","publication_year":2024,"publication_date":"2024-08-01","ids":{"openalex":"https://openalex.org/W4409411544","doi":"https://doi.org/10.61186/jbums.31.2.150"},"language":"en","primary_location":{"id":"doi:10.61186/jbums.31.2.150","doi":"https://doi.org/10.61186/jbums.31.2.150","is_oa":true,"landing_page_url":"https://doi.org/10.61186/jbums.31.2.150","pdf_url":"http://journal.bums.ac.ir/files/site1/user_files_948149/mohammadzadeh-A-10-3624-1-5ea7800.pdf","source":{"id":"https://openalex.org/S4404677467","display_name":"S\u0101ln\u0101mah va \u0101m\u0101r.","issn_l":"1027-2984","issn":["1027-2984"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Birjand University of Medical Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"http://journal.bums.ac.ir/files/site1/user_files_948149/mohammadzadeh-A-10-3624-1-5ea7800.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5051799332","display_name":"Saied Mohammadzadeh","orcid":"https://orcid.org/0000-0002-7791-9272","observed_orcids":["https://orcid.org/0000-0002-7791-9272"]},"institutions":[{"id":"https://openalex.org/I3123046734","display_name":"Lorestan University","ror":"https://ror.org/051bats05","country_code":"IR","type":"education","lineage":["https://openalex.org/I3123046734"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Saied Mohammadzadeh","raw_affiliation_strings":["Department of Animal Science, Faculty of Agriculture, Lorestan University, Khoramabad, Iran"],"raw_orcid":"https://orcid.org/0000-0002-7791-9272","affiliations":[{"raw_affiliation_string":"Department of Animal Science, Faculty of Agriculture, Lorestan University, Khoramabad, Iran","institution_ids":["https://openalex.org/I3123046734"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5090360740","display_name":"Mosayeb Amiri","orcid":"https://orcid.org/0000-0002-1129-7917","observed_orcids":["https://orcid.org/0000-0002-1129-7917"]},"institutions":[{"id":"https://openalex.org/I3123046734","display_name":"Lorestan University","ror":"https://ror.org/051bats05","country_code":"IR","type":"education","lineage":["https://openalex.org/I3123046734"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mosayeb Amiri","raw_affiliation_strings":["Department of Animal Science, Faculty of Agriculture, Lorestan University, Khoramabad, Iran"],"raw_orcid":"https://orcid.org/0000-0002-1129-7917","affiliations":[{"raw_affiliation_string":"Department of Animal Science, Faculty of Agriculture, Lorestan University, Khoramabad, Iran","institution_ids":["https://openalex.org/I3123046734"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5051799332"],"corresponding_institution_ids":["https://openalex.org/I3123046734"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"31","issue":"2","first_page":"150","last_page":"160"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9423999786376953,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10116","display_name":"Sperm and Testicular Function","score":0.9423999786376953,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":0.0203000009059906,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11146","display_name":"Hormonal and reproductive studies","score":0.00800000037997961,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/liraglutide","display_name":"liraglutide","score":1.0},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8109999895095825},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.8830000162124634},{"id":"https://openalex.org/keywords/male-reproductive-toxicity","display_name":"male reproductive toxicity","score":0.7889999747276306},{"id":"https://openalex.org/keywords/testis-histology","display_name":"testicular histology","score":0.859000027179718},{"id":"https://openalex.org/keywords/seminiferous-tubules","display_name":"seminiferous tubules","score":0.9710000157356262},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9879999756813049},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.7239999771118164},{"id":"https://openalex.org/keywords/blood-parameters","display_name":"blood parameters","score":0.6620000004768372},{"id":"https://openalex.org/keywords/glp-1-receptor-agonists","display_name":"GLP-1 receptor agonists","score":0.7639999985694885}],"concepts":[{"id":"https://openalex.org/C2781308992","wikidata":"https://www.wikidata.org/wiki/Q2526479","display_name":"Liraglutide","level":4,"score":0.9650352597236633},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.7278632521629333},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.577529788017273},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5700169801712036},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.552125871181488},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5259989500045776},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.1619238257408142}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.61186/jbums.31.2.150","doi":"https://doi.org/10.61186/jbums.31.2.150","is_oa":true,"landing_page_url":"https://doi.org/10.61186/jbums.31.2.150","pdf_url":"http://journal.bums.ac.ir/files/site1/user_files_948149/mohammadzadeh-A-10-3624-1-5ea7800.pdf","source":{"id":"https://openalex.org/S4404677467","display_name":"S\u0101ln\u0101mah va \u0101m\u0101r.","issn_l":"1027-2984","issn":["1027-2984"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Birjand University of Medical Sciences","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:d76611507f6b4c388478548f0cb8f7b0","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d76611507f6b4c388478548f0cb8f7b0","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"\u0645\u062c\u0644\u0647 \u062f\u0627\u0646\u0634\u06af\u0627\u0647 \u0639\u0644\u0648\u0645 \u067e\u0632\u0634\u06a9\u06cc \u0628\u06cc\u0631\u062c\u0646\u062f, Vol 31, Iss 2, Pp 150-160 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.61186/jbums.31.2.150","doi":"https://doi.org/10.61186/jbums.31.2.150","is_oa":true,"landing_page_url":"https://doi.org/10.61186/jbums.31.2.150","pdf_url":"http://journal.bums.ac.ir/files/site1/user_files_948149/mohammadzadeh-A-10-3624-1-5ea7800.pdf","source":{"id":"https://openalex.org/S4404677467","display_name":"S\u0101ln\u0101mah va \u0101m\u0101r.","issn_l":"1027-2984","issn":["1027-2984"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Birjand University of Medical Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409411544.pdf","grobid_xml":"https://content.openalex.org/works/W4409411544.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1975863662","https://openalex.org/W1986025060","https://openalex.org/W2034876552","https://openalex.org/W2046913589","https://openalex.org/W2161627055","https://openalex.org/W2282999229","https://openalex.org/W2612901232","https://openalex.org/W2626499453","https://openalex.org/W2744929350","https://openalex.org/W2767263655","https://openalex.org/W2781873092","https://openalex.org/W2788211509","https://openalex.org/W2911630547","https://openalex.org/W2946341900","https://openalex.org/W2971571571","https://openalex.org/W2974231197","https://openalex.org/W2986611753","https://openalex.org/W2989934368","https://openalex.org/W3015945042","https://openalex.org/W3027890954","https://openalex.org/W3037509338","https://openalex.org/W3045426548","https://openalex.org/W3128190703","https://openalex.org/W3172115200","https://openalex.org/W4200013705","https://openalex.org/W4376121414"],"related_works":["https://openalex.org/W7220456397","https://openalex.org/W4393011574","https://openalex.org/W4383956101","https://openalex.org/W4400913755","https://openalex.org/W2810499705","https://openalex.org/W4412890287","https://openalex.org/W7092179277","https://openalex.org/W3037509338","https://openalex.org/W2962921781","https://openalex.org/W2146745170"],"abstract_inverted_index":{"Background":[0],"and":[1,4,45,54,82,113,116,128,150,159,178,199,206],"Aims:":[2],"Obesity":[3],"diabetes":[5],"are":[6],"the":[7,19,28,38,83,99,104,107,109,136,143,162,165,189,195],"most":[8],"common":[9],"metabolic":[10],"disorders":[11],"that":[12,142],"have":[13],"negative":[14],"effects":[15],"on":[16,42],"organisms,":[17],"including":[18],"reproductive":[20,197],"system.The":[21],"drug":[22],"treatments":[23],"cause":[24],"fertility":[25],"disorders.One":[26],"of":[27,40,57,78,90,98,106,145,164,169],"candidate":[29],"drugs":[30],"is":[31],"liraglutide.The":[32],"present":[33],"study":[34],"sought":[35],"to":[36,64,135],"assess":[37],"effect":[39],"liraglutide":[41,156,184,192],"testicular":[43,117],"tissue":[44,130],"blood":[46,114],"parameters,":[47],"especially":[48],"C-reactive":[49,173],"protein":[50,174],"(inflammation":[51],"index).":[52],"Materials":[53],"Methods:A":[55],"total":[56],"40":[58],"adult":[59],"male":[60,196],"mice":[61],"were":[62,111,119,121,126,132],"assigned":[63],"five":[65],"groups":[66,70,152,180],"with":[67,183],"eight":[68],"replications.These":[69],"included":[71],"control,":[72],"obese,":[73],"obese+liraglutide":[74],"injected":[75,87,94,182],"1.2":[76,88],"mg/kg":[77,89],"body":[79,91],"weight,":[80],"diabetes,":[81],"last":[84],"group,":[85],"diabetes+liraglutide":[86],"weight.Liraglutide":[92],"was":[93,101,153],"subcutaneously":[95],"daily.The":[96],"duration":[97],"experiment":[100],"six":[102],"weeks.After":[103],"end":[105],"experiment,":[108],"animals":[110],"anesthetized,":[112],"samples":[115],"sections":[118,131],"taken.Animals":[120],"euthanized":[122],"(cervical":[123],"dislocation).The":[124],"testicles":[125],"removed":[127],"fixed.The":[129],"prepared":[133],"according":[134],"usual":[137],"protocol.Results:":[138],"The":[139],"results":[140,190],"demonstrated":[141],"diameter":[144],"seminiferous":[146,170],"tubules":[147,171],"in":[148,176],"obese":[149,179],"diabetic":[151,177],"increased":[154],"by":[155,188,204],"injection":[157],"(P<0.01).Diabetes":[158],"obesity":[160,205],"decreased":[161,175],"thickness":[163],"germ":[166],"cell":[167],"epithelium":[168],"(P<0.01).The":[172],"when":[181],"(P<0.01).":[185],"Conclusion:As":[186],"evidenced":[187],"obtained,":[191],"can":[193],"improve":[194],"system":[198],"reduce":[200],"chronic":[201],"inflammation":[202],"caused":[203],"diabetes.":[207]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-04-14T00:00:00"}