{"id":"https://openalex.org/W4409399580","doi":"https://doi.org/10.2139/ssrn.5213123","title":"\"Triazole-Oxadiazole-Based Schiff Bases as Potential Kinase Inhibitors: Synthesis, Dft Studies, Molecular Docking and Anticancer Evaluation\"","display_name":"\"Triazole-Oxadiazole-Based Schiff Bases as Potential Kinase Inhibitors: Synthesis, Dft Studies, Molecular Docking and Anticancer Evaluation\"","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4409399580","doi":"https://doi.org/10.2139/ssrn.5213123"},"language":"en","primary_location":{"id":"doi:10.2139/ssrn.5213123","doi":"https://doi.org/10.2139/ssrn.5213123","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.5213123","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"volume":null,"type":"preprint","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.2139/ssrn.5213123","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040358746","display_name":"Yogesh O. Bhola","orcid":"https://orcid.org/0000-0002-8882-5714","observed_orcids":["https://orcid.org/0000-0002-8882-5714"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Yogesh Bhola","raw_affiliation_strings":["Shri M.P.Pandya Science College Lunawada-389230 Gujarat"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shri M.P.Pandya Science College Lunawada-389230 Gujarat","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117127251","display_name":"Jay B. Maheta","orcid":"https://orcid.org/0009-0003-9332-1056","observed_orcids":["https://orcid.org/0009-0003-9332-1056"]},"institutions":[{"id":"https://openalex.org/I4405263164","display_name":"Shri Govind Guru University","ror":"https://ror.org/03f6bd050","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405263164"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Jay  B. Maheta","raw_affiliation_strings":["Shri Govind Guru University, Vinzol, Godhra, 389001, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shri Govind Guru University, Vinzol, Godhra, 389001, India","institution_ids":["https://openalex.org/I4405263164"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nargis  H. Shaikh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nargis  H. Shaikh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117127252","display_name":"Darshna K. Lakhnotra","orcid":"https://orcid.org/0009-0005-0953-2585","observed_orcids":["https://orcid.org/0009-0005-0953-2585"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Darshna  K. Lakhnotra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5117127253","display_name":"Ila M. Ram","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ila  M. Ram","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103209955","display_name":"Anjali B. Thakkar","orcid":"https://orcid.org/0009-0005-4407-8891","observed_orcids":["https://orcid.org/0009-0005-4407-8891"]},"institutions":[{"id":"https://openalex.org/I4405284406","display_name":"Sardar Patel University Mandi","ror":"https://ror.org/03gm0gg03","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405284406"]},{"id":"https://openalex.org/I57085157","display_name":"Sardar Patel University","ror":"https://ror.org/05kfstc28","country_code":"IN","type":"education","lineage":["https://openalex.org/I57085157"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anjali Thakkar","raw_affiliation_strings":["Sardar Patel University","Sardar Patel University, Room No. 105, Thin Film Lab, Department of Physics, Sardar Patel University, Vallabh Vidyanagar, IN 388120, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sardar Patel University","institution_ids":["https://openalex.org/I4405284406","https://openalex.org/I57085157"]},{"raw_affiliation_string":"Sardar Patel University, Room No. 105, Thin Film Lab, Department of Physics, Sardar Patel University, Vallabh Vidyanagar, IN 388120, India","institution_ids":["https://openalex.org/I57085157"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Parth Thakor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Parth Thakor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5089530898","display_name":"R. B. Subramanian","orcid":"https://orcid.org/0000-0002-4322-9513","observed_orcids":["https://orcid.org/0000-0002-4322-9513"]},"institutions":[{"id":"https://openalex.org/I4405284406","display_name":"Sardar Patel University Mandi","ror":"https://ror.org/03gm0gg03","country_code":"IN","type":"education","lineage":["https://openalex.org/I4405284406"]},{"id":"https://openalex.org/I57085157","display_name":"Sardar Patel University","ror":"https://ror.org/05kfstc28","country_code":"IN","type":"education","lineage":["https://openalex.org/I57085157"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R.  B. Subramanian","raw_affiliation_strings":["Sardar Patel University","Sardar Patel University, Room No. 105, Thin Film Lab, Department of Physics, Sardar Patel University, Vallabh Vidyanagar, IN 388120, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sardar Patel University","institution_ids":["https://openalex.org/I4405284406","https://openalex.org/I57085157"]},{"raw_affiliation_string":"Sardar Patel University, Room No. 105, Thin Film Lab, Department of Physics, Sardar Patel University, Vallabh Vidyanagar, IN 388120, India","institution_ids":["https://openalex.org/I57085157"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5040358746"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds","score":0.5077999830245972,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds","score":0.5077999830245972,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.3433000147342682,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds","score":0.10249999910593033,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/schiff-base","display_name":"Schiff base","score":0.7429999709129333},{"id":"https://openalex.org/keywords/1-3-4-oxadiazole-derivatives","display_name":"1,3,4-oxadiazole derivatives","score":0.8939999938011169},{"id":"https://openalex.org/keywords/kinase-inhibitors","display_name":"kinase inhibitors","score":0.9660000205039978},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.953000009059906},{"id":"https://openalex.org/keywords/a549-lung-carcinoma-cells","display_name":"A549 lung carcinoma cells","score":0.9290000200271606},{"id":"https://openalex.org/keywords/admet-properties","display_name":"ADMET properties","score":0.6949999928474426},{"id":"https://openalex.org/keywords/nonlinear-optical-properties","display_name":"nonlinear optical properties","score":0.7829999923706055},{"id":"https://openalex.org/keywords/homo-lumo-analysis","display_name":"HOMO-LUMO analysis","score":0.871999979019165},{"id":"https://openalex.org/keywords/molecular-docking","display_name":"molecular docking","score":0.6710000038146973},{"id":"https://openalex.org/keywords/drug-likeness","display_name":"drug-likeness","score":0.6129999756813049}],"concepts":[{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.7497011423110962},{"id":"https://openalex.org/C2779448499","wikidata":"https://www.wikidata.org/wiki/Q1227206","display_name":"Oxadiazole","level":2,"score":0.7326120138168335},{"id":"https://openalex.org/C2777907353","wikidata":"https://www.wikidata.org/wiki/Q903341","display_name":"Triazole","level":2,"score":0.6296518445014954},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5600623488426208},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.5370681881904602},{"id":"https://openalex.org/C2776428424","wikidata":"https://www.wikidata.org/wiki/Q2602701","display_name":"Schiff base","level":2,"score":0.4510185718536377},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.374967485666275},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.34184229373931885},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.135428786277771},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13199204206466675},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2139/ssrn.5213123","doi":"https://doi.org/10.2139/ssrn.5213123","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.5213123","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.2139/ssrn.5213123","doi":"https://doi.org/10.2139/ssrn.5213123","is_oa":true,"landing_page_url":"https://doi.org/10.2139/ssrn.5213123","pdf_url":null,"source":{"id":"https://openalex.org/S4210172589","display_name":"SSRN Electronic Journal","issn_l":"1556-5068","issn":["1556-5068"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1318003438","host_organization_name":"RELX Group (Netherlands)","host_organization_lineage":["https://openalex.org/I1318003438"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1575679998","https://openalex.org/W1964103520","https://openalex.org/W1966225819","https://openalex.org/W1980670485","https://openalex.org/W1983152916","https://openalex.org/W2008141313","https://openalex.org/W2017900327","https://openalex.org/W2017975422","https://openalex.org/W2029833930","https://openalex.org/W2029899084","https://openalex.org/W2030931791","https://openalex.org/W2032935140","https://openalex.org/W2035191998","https://openalex.org/W2041089613","https://openalex.org/W2055559046","https://openalex.org/W2064574734","https://openalex.org/W2069397868","https://openalex.org/W2072194546","https://openalex.org/W2085750104","https://openalex.org/W2086946795","https://openalex.org/W2090844661","https://openalex.org/W2130706492","https://openalex.org/W2513660640","https://openalex.org/W2589041979","https://openalex.org/W2618719143","https://openalex.org/W2619165690","https://openalex.org/W2649942267","https://openalex.org/W2776290859","https://openalex.org/W2884762656","https://openalex.org/W2947961706","https://openalex.org/W2993225800","https://openalex.org/W3031889867","https://openalex.org/W3049670213","https://openalex.org/W3104581305","https://openalex.org/W3107156378","https://openalex.org/W3109391413","https://openalex.org/W3133126029","https://openalex.org/W3157921093","https://openalex.org/W3158361078","https://openalex.org/W3177235522","https://openalex.org/W4210713621","https://openalex.org/W4212919239","https://openalex.org/W4224293578","https://openalex.org/W4303954670","https://openalex.org/W4310155343","https://openalex.org/W4382010845","https://openalex.org/W4403978829"],"related_works":["https://openalex.org/W4206738596","https://openalex.org/W7161815249","https://openalex.org/W7092295482","https://openalex.org/W4403401973","https://openalex.org/W7164578699","https://openalex.org/W4415726345","https://openalex.org/W2279243579","https://openalex.org/W2889711538","https://openalex.org/W2626252405","https://openalex.org/W7213888056"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-04-13T00:00:00"}