{"id":"https://openalex.org/W44092459","doi":null,"title":"Fluoroaluminates mimic muscarinic- and oxytocin-receptor-mediated generation of inositol phosphates and contraction in the intact guinea-pig myometrium. Role for a pertussis/cholera-toxin-insensitive G protein.","display_name":"Fluoroaluminates mimic muscarinic- and oxytocin-receptor-mediated generation of inositol phosphates and contraction in the intact guinea-pig myometrium. Role for a pertussis/cholera-toxin-insensitive G protein.","publication_year":1988,"publication_date":"1988-10-15","ids":{"openalex":"https://openalex.org/W44092459","mag":"44092459","pmid":"https://pubmed.ncbi.nlm.nih.gov/2849425","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1135283"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:4408402","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1135283","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1135283","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078690951","display_name":"Sylvie Marc","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"S Marc","raw_affiliation_strings":["Endocrinologie et R\u00e9gulations Cellulaires, CNRS UA 1131, Orsay, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Endocrinologie et R\u00e9gulations Cellulaires, CNRS UA 1131, Orsay, France","institution_ids":["https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050303748","display_name":"Denis Leiber","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D Leiber","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5014363728","display_name":"Simone Harbon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S Harbon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.7872,"has_fulltext":false,"cited_by_count":79,"citation_normalized_percentile":{"value":0.91724514,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"255","issue":"2","first_page":"705","last_page":"13"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9531000256538391,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9531000256538391,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.03759999945759773,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12434","display_name":"Phosphodiesterase function and regulation","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluoroaluminate","display_name":"fluoroaluminate","score":0.9750000238418579},{"id":"https://openalex.org/keywords/myometrium","display_name":"myometrium","score":0.7210000157356262},{"id":"https://openalex.org/keywords/inositol-phosphates","display_name":"inositol phosphates","score":0.8410000205039978},{"id":"https://openalex.org/keywords/phospholipase-c","display_name":"phospholipase C","score":0.8420000076293945},{"id":"https://openalex.org/keywords/muscarinic-receptors","display_name":"muscarinic receptors","score":0.9269999861717224},{"id":"https://openalex.org/keywords/oxytocin-receptor","display_name":"oxytocin receptor","score":0.9240000247955322},{"id":"https://openalex.org/keywords/camp","display_name":"cyclic AMP","score":0.7110000252723694},{"id":"https://openalex.org/keywords/prostacyclin","display_name":"prostacyclin","score":0.7350000143051147},{"id":"https://openalex.org/keywords/uterine-contraction","display_name":"uterine contraction","score":0.9150000214576721},{"id":"https://openalex.org/keywords/pertussis-toxin","display_name":"pertussis toxin","score":0.8019999861717224},{"id":"https://openalex.org/keywords/cholera-toxin","display_name":"cholera toxin","score":0.9959999918937683},{"id":"https://openalex.org/keywords/phosphoinositide-cycle","display_name":"phosphoinositide cycle","score":0.7059999704360962},{"id":"https://openalex.org/keywords/carbachol","display_name":"carbachol","score":0.6240000128746033},{"id":"https://openalex.org/keywords/guanine-nucleotide-regulatory-protein","display_name":"guanine nucleotide regulatory protein","score":0.6000000238418579}],"concepts":[{"id":"https://openalex.org/C49773422","wikidata":"https://www.wikidata.org/wiki/Q4859345","display_name":"Pertussis toxin","level":4,"score":0.742772102355957},{"id":"https://openalex.org/C2778618036","wikidata":"https://www.wikidata.org/wiki/Q2878809","display_name":"Inositol phosphate","level":4,"score":0.6888757348060608},{"id":"https://openalex.org/C2777006276","wikidata":"https://www.wikidata.org/wiki/Q83586","display_name":"Cholera toxin","level":2,"score":0.6872301697731018},{"id":"https://openalex.org/C33789571","wikidata":"https://www.wikidata.org/wiki/Q410959","display_name":"Muscarinic acetylcholine receptor","level":3,"score":0.6298450827598572},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6240982413291931},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6235145330429077},{"id":"https://openalex.org/C2777427919","wikidata":"https://www.wikidata.org/wiki/Q407997","display_name":"Inositol","level":3,"score":0.6159303784370422},{"id":"https://openalex.org/C2778597717","wikidata":"https://www.wikidata.org/wiki/Q420248","display_name":"Phospholipase C","level":3,"score":0.584272563457489},{"id":"https://openalex.org/C2778988552","wikidata":"https://www.wikidata.org/wiki/Q419401","display_name":"Carbachol","level":3,"score":0.5468569993972778},{"id":"https://openalex.org/C66135807","wikidata":"https://www.wikidata.org/wiki/Q24726231","display_name":"Gq alpha subunit","level":4,"score":0.5034725069999695},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4999725818634033},{"id":"https://openalex.org/C2781387506","wikidata":"https://www.wikidata.org/wiki/Q138145","display_name":"Inositol trisphosphate","level":4,"score":0.4787158966064453},{"id":"https://openalex.org/C80631254","wikidata":"https://www.wikidata.org/wiki/Q407438","display_name":"G protein","level":3,"score":0.4663718342781067},{"id":"https://openalex.org/C2910325308","wikidata":"https://www.wikidata.org/wiki/Q65920385","display_name":"Adenylate Cyclase Toxin","level":5,"score":0.4416868984699249},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.42525696754455566},{"id":"https://openalex.org/C2779276759","wikidata":"https://www.wikidata.org/wiki/Q412747","display_name":"Forskolin","level":3,"score":0.41701316833496094},{"id":"https://openalex.org/C181612422","wikidata":"https://www.wikidata.org/wiki/Q14908140","display_name":"Oxytocin receptor","level":3,"score":0.4147465229034424},{"id":"https://openalex.org/C2776176026","wikidata":"https://www.wikidata.org/wiki/Q169960","display_name":"Oxytocin","level":2,"score":0.3700246512889862},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35452431440353394},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.29011082649230957},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.2833693027496338},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.06160566210746765}],"mesh":[{"descriptor_ui":"D000077410","descriptor_name":"Aluminum Chloride","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000242","descriptor_name":"Cyclic AMP","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000535","descriptor_name":"Aluminum","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001285","descriptor_name":"Atropine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002217","descriptor_name":"Carbachol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D002712","descriptor_name":"Chlorides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004717","descriptor_name":"Endometrium","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005459","descriptor_name":"Fluorides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006168","descriptor_name":"Guinea Pigs","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007295","descriptor_name":"Inositol Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009215","descriptor_name":"Myometrium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D010566","descriptor_name":"Virulence Factors, Bordetella","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011945","descriptor_name":"Receptors, Angiotensin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011976","descriptor_name":"Receptors, Muscarinic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012969","descriptor_name":"Sodium Fluoride","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D013403","descriptor_name":"Sugar Phosphates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014590","descriptor_name":"Uterine Contraction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D017607","descriptor_name":"Aluminum Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018045","descriptor_name":"Receptors, Oxytocin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019204","descriptor_name":"GTP-Binding Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037342","descriptor_name":"Pertussis Toxin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037361","descriptor_name":"Adenylate Cyclase Toxin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:4408402","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1135283","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1135283","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1135283","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochem J","raw_type":"Text"},{"id":"pmid:2849425","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2849425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Biochemical journal","raw_type":"Journal Article"},{"id":"mag:44092459","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2849425","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4408402","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1135283","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.504800021648407,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1498162448","https://openalex.org/W1498793897","https://openalex.org/W1499930709","https://openalex.org/W1521095349","https://openalex.org/W1532747508","https://openalex.org/W1567061008","https://openalex.org/W1568982528","https://openalex.org/W1570939625","https://openalex.org/W1573718340","https://openalex.org/W1579588798","https://openalex.org/W1598028013","https://openalex.org/W1598199924","https://openalex.org/W1617966995","https://openalex.org/W1649341288","https://openalex.org/W1775749144","https://openalex.org/W1895492779","https://openalex.org/W1927894522","https://openalex.org/W1969755572","https://openalex.org/W1971497403","https://openalex.org/W1978274173","https://openalex.org/W1978966292","https://openalex.org/W1982960066","https://openalex.org/W1996466550","https://openalex.org/W2003138126","https://openalex.org/W2006050008","https://openalex.org/W2031750572","https://openalex.org/W2036145275","https://openalex.org/W2047149593","https://openalex.org/W2068877244","https://openalex.org/W2074920577","https://openalex.org/W2080875376","https://openalex.org/W2089719236","https://openalex.org/W2093113620","https://openalex.org/W2093837825","https://openalex.org/W2117750174","https://openalex.org/W2179950846","https://openalex.org/W2222512631","https://openalex.org/W2252304077","https://openalex.org/W2296863699","https://openalex.org/W2341312002","https://openalex.org/W2398581996","https://openalex.org/W2405330845","https://openalex.org/W2407105744","https://openalex.org/W2416991706","https://openalex.org/W2419481833"],"related_works":["https://openalex.org/W2037010431","https://openalex.org/W2006050008","https://openalex.org/W1998133234","https://openalex.org/W78009209","https://openalex.org/W2010253164","https://openalex.org/W2326779838","https://openalex.org/W2343697031","https://openalex.org/W1902182564","https://openalex.org/W7097492455","https://openalex.org/W2341774505"],"abstract_inverted_index":{"1.":[0],"In":[1],"the":[2,17,22,50,62,76,80,85,93,100,130,164,182,189,195,200,221,238,248],"intact":[3],"guinea-pig":[4],"myometrium,":[5,183],"carbachol":[6,53,104],"and":[7,28,54,112,142,194,209,219,229],"oxytocin":[8,55,210],"stimulated":[9],"a":[10,59,158,185,244],"specific":[11],"receptor-mediated":[12],"phospholipase":[13,213],"C":[14,214],"activation,":[15],"catalysing":[16],"breakdown":[18],"of":[19,25,31,38,52,64,103,132,163,191],"PtdIns(4,5)P2":[20],"with":[21],"sequential":[23],"generation":[24,63,190],"InsP3,":[26],"InsP2":[27],"InsP.":[29],"Stimulation":[30],"muscarinic":[32,165,208],"receptors":[33,211,225],"also":[34],"triggered":[35],"an":[36],"inhibition":[37],"cyclic":[39,106,144,231],"AMP":[40,107,145,232],"accumulation":[41],"caused":[42],"by":[43,56,173],"prostacyclin.":[44],"2.":[45],"NaF":[46],"plus":[47],"AlCl3":[48,74],"mimicked":[49],"effects":[51],"inducing,":[57],"in":[58,115,181],"dose-dependent":[60],"manner,":[61],"all":[65],"three":[66],"inositol":[67,116,153,166,192],"phosphates":[68,193],"as":[69,71,118,120],"well":[70,119],"uterine":[72],"contractions.":[73],"enhanced":[75],"fluoride":[77],"effect,":[78],"supporting":[79],"concept":[81],"that":[82,204,223],"A1F4-":[83],"was":[84,134,170],"active":[86],"species.":[87],"Under":[88],"similar":[89],"conditions,":[90],"fluoroaluminates":[91],"activated":[92],"guanine":[94],"nucleotide":[95],"regulatory":[96],"protein":[97,187,203],"Gi,":[98],"reproducing":[99],"inhibitory":[101],"effect":[102],"on":[105],"concentrations.":[108],"3.":[109],"Both":[110],"carbachol-":[111],"oxytocin-mediated":[113],"increases":[114],"phosphates,":[117],"contractions,":[121],"were":[122],"insensitive":[123],"to":[124,148,212,226,236],"pertussis":[125],"toxin,":[126,138],"under":[127],"conditions":[128],"where":[129],"expression":[131],"Gi":[133,218],"totally":[135],"prevented.":[136],"Cholera":[137],"which":[139,169],"activates":[140],"Gs":[141],"enhances":[143],"accumulation,":[146],"failed":[147],"affect":[149],"basal":[150],"or":[151],"oxytocin-evoked":[152],"phosphate":[154,167],"generation,":[155],"but":[156,241],"induced":[157],"slight,":[159],"though":[160],"consistent,":[161],"attenuation":[162],"response,":[168],"similarly":[171],"evoked":[172],"forskolin.":[174],"4.":[175],"The":[176],"data":[177],"provide":[178],"evidence":[179],"that,":[180],"(a)":[184],"G":[186,202],"mediates":[188],"Ca2+-dependent":[196],"contractile":[197],"event,":[198],"(b)":[199],"relevant":[201],"most":[205],"probably":[206],"couples":[207],"is":[215],"different":[216],"from":[217],"Gs,":[220],"proteins":[222],"couple":[224],"adenylate":[227],"cyclase,":[228],"(c)":[230],"does":[233],"not":[234],"seem":[235],"control":[237],"phosphoinositide":[239],"cycle,":[240],"rather":[242],"exerts":[243],"negative":[245],"regulation":[246],"at":[247],"muscarinic-receptor":[249],"level.":[250]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}