{"id":"https://openalex.org/W4409222091","doi":"https://doi.org/10.1161/atvb.39.suppl_1.635","title":"Abstract 635: Satellite Cells Play a Role in Revascularization of Ischemic Tissue","display_name":"Abstract 635: Satellite Cells Play a Role in Revascularization of Ischemic Tissue","publication_year":2019,"publication_date":"2019-05-01","ids":{"openalex":"https://openalex.org/W4409222091","doi":"https://doi.org/10.1161/atvb.39.suppl_1.635"},"language":"en","primary_location":{"id":"doi:10.1161/atvb.39.suppl_1.635","doi":"https://doi.org/10.1161/atvb.39.suppl_1.635","is_oa":false,"landing_page_url":"https://doi.org/10.1161/atvb.39.suppl_1.635","pdf_url":null,"source":{"id":"https://openalex.org/S3485792","display_name":"Arteriosclerosis Thrombosis and Vascular Biology","issn_l":"1079-5642","issn":["1079-5642","1524-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, Thrombosis, and Vascular Biology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020809156","display_name":"Laura Hansen","orcid":"https://orcid.org/0000-0002-3936-9476","observed_orcids":["https://orcid.org/0000-0002-3936-9476"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura M Hansen","raw_affiliation_strings":["Emory Univ, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Univ, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101611380","display_name":"Wenxue Liu","orcid":"https://orcid.org/0000-0003-0569-3064","observed_orcids":["https://orcid.org/0000-0003-0569-3064"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wenxue Liu","raw_affiliation_strings":["Emory Univ, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Univ, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103573122","display_name":"Giji Joseph","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Giji Joseph","raw_affiliation_strings":["Emory Univ, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Univ, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016501769","display_name":"William Robert Taylor","orcid":"https://orcid.org/0000-0002-5765-2419","observed_orcids":["https://orcid.org/0000-0002-5765-2419"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Robert Taylor","raw_affiliation_strings":["Emory Univ, Atlanta, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Univ, Atlanta, GA","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I150468666"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"39","issue":"Suppl_1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.7562999725341797,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer","score":0.7562999725341797,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.09889999777078629,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.048500001430511475,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/satellite-cells","display_name":"satellite cells","score":0.9729999899864197},{"id":"https://openalex.org/keywords/skeletal-muscle-progenitor-cells","display_name":"skeletal muscle progenitor cells","score":0.8700000047683716},{"id":"https://openalex.org/keywords/peripheral-arterial-disease","display_name":"peripheral arterial disease","score":0.9440000057220459},{"id":"https://openalex.org/keywords/hindlimb-ischemia","display_name":"hindlimb ischemia","score":0.9679999947547913},{"id":"https://openalex.org/keywords/vascular-development","display_name":"vascular development","score":0.5490000247955322},{"id":"https://openalex.org/keywords/endothelial-cell-migration","display_name":"endothelial cell migration","score":0.9070000052452087},{"id":"https://openalex.org/keywords/smooth-muscle-cell-migration","display_name":"smooth muscle cell migration","score":0.9890000224113464},{"id":"https://openalex.org/keywords/alginate-encapsulation","display_name":"alginate encapsulation","score":0.6759999990463257},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.7480000257492065},{"id":"https://openalex.org/keywords/vasculogenesis","display_name":"vasculogenesis","score":0.5569999814033508},{"id":"https://openalex.org/keywords/capillary-density","display_name":"capillary density","score":0.3869999945163727}],"concepts":[{"id":"https://openalex.org/C2779464278","wikidata":"https://www.wikidata.org/wiki/Q7317735","display_name":"Revascularization","level":3,"score":0.6235743165016174},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5374596118927002},{"id":"https://openalex.org/C19269812","wikidata":"https://www.wikidata.org/wiki/Q26540","display_name":"Satellite","level":2,"score":0.49160581827163696},{"id":"https://openalex.org/C541997718","wikidata":"https://www.wikidata.org/wiki/Q188151","display_name":"Ischemia","level":2,"score":0.4176560044288635},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4133296012878418},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3955593705177307},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.17309769988059998},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1161/atvb.39.suppl_1.635","doi":"https://doi.org/10.1161/atvb.39.suppl_1.635","is_oa":false,"landing_page_url":"https://doi.org/10.1161/atvb.39.suppl_1.635","pdf_url":null,"source":{"id":"https://openalex.org/S3485792","display_name":"Arteriosclerosis Thrombosis and Vascular Biology","issn_l":"1079-5642","issn":["1079-5642","1524-4636"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arteriosclerosis, Thrombosis, and Vascular Biology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4285369241","https://openalex.org/W2922220631","https://openalex.org/W4387270369","https://openalex.org/W3177191734","https://openalex.org/W3106606479","https://openalex.org/W4389034253","https://openalex.org/W7125586273","https://openalex.org/W3033431247","https://openalex.org/W4400968270","https://openalex.org/W7000973302"],"abstract_inverted_index":{"Peripheral":[0],"artery":[1],"disease":[2,21],"(PAD)":[3],"is":[4,22],"a":[5,67,101,110,135,150,174,179,327],"major":[6],"health":[7],"problem":[8],"affecting":[9],"an":[10],"estimated":[11],"12-20%":[12],"of":[13,138,241,314,323],"the":[14,28,35,145,158,230,238,246,311],"U.S.":[15],"population":[16],"60":[17],"and":[18,37,46,53,127,160,188,208,213,256,270,288,319],"older.":[19],"The":[20],"caused":[23],"by":[24,58,201,222,234,244,262],"atherosclerotic":[25],"lesions":[26],"in":[27,39,61,91,103,109,122,149,154,166,173,284,317],"peripheral":[29],"arteries":[30],"restricting":[31],"blood":[32],"flow":[33],"to":[34,70,78,120,141,184,196,218,229,250,286,292,302],"issue":[36],"results":[38,309],"pain,":[40],"decreased":[41],"mobility,":[42],"poor":[43],"wound":[44],"healing,":[45],"amputations.":[47],"Current":[48],"treatment":[49],"strategies":[50],"are":[51,85,282],"limited":[52],"include":[54],"lifestyle":[55],"modifications":[56],"followed":[57],"surgical":[59],"intervention":[60],"severe":[62],"cases.":[63],"Thus,":[64],"there":[65],"remains":[66],"pressing":[68],"need":[69],"develop":[71],"new":[72],"therapeutic":[73,239],"approaches":[74],"which":[75,118,191],"we":[76,95,277],"propose":[77],"fill":[79],"with":[80,252],"satellite":[81,113,155,167,186,193,226,242,248,254,280,297,315,324],"cells.":[82,156],"Satellite":[83],"cells":[84,89,114,168,187,194,227,243,249,255,281,298,316,325],"skeletal":[86],"muscle":[87,92,129],"progenitor":[88],"important":[90],"repair;":[93],"however,":[94],"hypothesized":[96],"that":[97,258,279,307],"they":[98],"also":[99],"play":[100],"role":[102,313],"promoting":[104],"vascular":[105,143,199],"growth.":[106],"We":[107,177,215,236,305],"found":[108,189,257],"co-culture":[111],"system,":[112],"produced":[115],"chemoattractant":[116],"factors":[117,290],"led":[119],"increases":[121],"both":[123,202],"endothelial":[124],"(2.8":[125],"fold)":[126,132],"smooth":[128],"cell":[130,161],"(3.5":[131],"migration.":[133],"In":[134,275],"murine":[136],"model":[137],"hindlimb":[139],"ischemia":[140,287],"study":[142],"growth,":[144],"ischemic":[146,171],"insult":[147],"resulted":[148],"3.4":[151],"fold":[152],"increase":[153,233],"Additionally,":[157,295],"vasculogenesis":[159],"migration":[162],"pathways":[163],"were":[164,216],"enriched":[165],"isolated":[169],"from":[170],"limbs":[172],"microarray":[175],"analysis.":[176],"used":[178],"tamoxifen":[180],"inducible":[181],"cre-lox":[182],"system":[183],"deplete":[185],"mice":[190,231,251],"lacked":[192],"appeared":[195],"have":[197],"impaired":[198],"growth":[200],"Laser":[203],"Doppler":[204],"Perfusion":[205],"Imaging":[206],"(LDPI)":[207],"histological":[209],"staining":[210],"for":[211,330],"capillaries":[212,266],"arterioles.":[214],"able":[217],"rescue":[219],"this":[220],"phenotype":[221],"delivering":[223,245],"alginate":[224],"encapsulated":[225,247],"back":[228],"(15%":[232],"LDPI).":[235],"tested":[237],"potential":[240],"intact":[253],"perfusion":[259],"was":[260],"increased":[261,267,272],"28%":[263],"using":[264],"LDPI,":[265],"1.8":[268],"fold,":[269],"arterioles/arteries":[271],"2.4":[273],"fold.":[274],"conclusion,":[276],"showed":[278],"activated":[283],"response":[285],"produce":[289],"critical":[291],"robust":[293],"revascularization.":[294],"exogenous":[296],"can":[299],"be":[300],"delivered":[301],"improve":[303],"vascularization.":[304],"believe":[306],"these":[308],"demonstrate":[310],"crucial":[312],"vascularization":[318],"support":[320],"further":[321],"development":[322],"as":[326],"novel":[328],"therapy":[329],"PAD.":[331]},"counts_by_year":[],"updated_date":"2026-10-02T10:15:12.560889","created_date":"2025-04-07T00:00:00"}