{"id":"https://openalex.org/W4409147347","doi":"https://doi.org/10.1016/j.jhazmat.2025.138145","title":"PM2.5 exacerbates nasal epithelial barrier dysfunction in allergic rhinitis by inducing NLRP3-mediated pyroptosis via the AhR/CYP1A1/ROS axis","display_name":"PM2.5 exacerbates nasal epithelial barrier dysfunction in allergic rhinitis by inducing NLRP3-mediated pyroptosis via the AhR/CYP1A1/ROS axis","publication_year":2025,"publication_date":"2025-04-04","ids":{"openalex":"https://openalex.org/W4409147347","doi":"https://doi.org/10.1016/j.jhazmat.2025.138145","pmid":"https://pubmed.ncbi.nlm.nih.gov/40209413"},"language":"en","primary_location":{"id":"doi:10.1016/j.jhazmat.2025.138145","doi":"https://doi.org/10.1016/j.jhazmat.2025.138145","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jhazmat.2025.138145","pdf_url":null,"source":{"id":"https://openalex.org/S145089992","display_name":"Journal of Hazardous Materials","issn_l":"0304-3894","issn":["0304-3894","1873-3336"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hazardous Materials","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009842162","display_name":"JiaSheng Yuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]},{"id":"https://openalex.org/I4210127074","display_name":"Zhongshan Hospital","ror":"https://ror.org/032x22645","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210127074"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiasheng Yuan","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Department of Otorhinolaryngology-Head and Neck Surgery, Zhongshan Hospital, Fudan University, Shanghai 200030, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China; Department of Otorhinolaryngology-Head and Neck Surgery, Zhongshan Hospital, Fudan University, Shanghai 200030, China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I24943067","https://openalex.org/I4210108480","https://openalex.org/I4210127074"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Zhihuai Liao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhihuai Liao","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101539456","display_name":"Xinhua Zhu","orcid":"https://orcid.org/0000-0002-3801-6329","observed_orcids":["https://orcid.org/0000-0002-3801-6329"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhua Zhu","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061970652","display_name":"Yaqiong Zhu","orcid":"https://orcid.org/0000-0002-1974-3221","observed_orcids":["https://orcid.org/0000-0002-1974-3221"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yaqiong Zhu","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Shuhong Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuhong Wu","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112970176","display_name":"Liqing Guo","orcid":"https://orcid.org/0000-0002-7251-302X","observed_orcids":["https://orcid.org/0000-0002-7251-302X"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liqing Guo","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102374225","display_name":"Yanpeng Fu","orcid":"https://orcid.org/0000-0002-0821-4754","observed_orcids":["https://orcid.org/0000-0002-0821-4754","https://orcid.org/0009-0002-5289-1901"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanpeng Fu","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100751646","display_name":"Yuehui Liu","orcid":"https://orcid.org/0000-0002-3217-9178","observed_orcids":["https://orcid.org/0000-0002-3217-9178","https://orcid.org/0000-0003-2182-946X"]},"institutions":[{"id":"https://openalex.org/I141649914","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23","country_code":"CN","type":"education","lineage":["https://openalex.org/I141649914"]},{"id":"https://openalex.org/I4210108480","display_name":"Second Affiliated Hospital of Nanchang University","ror":"https://ror.org/01nxv5c88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210108480"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yuehui Liu","raw_affiliation_strings":["Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China. Electronic address: liuyuehuiclark@21cn.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang 330006, China. Electronic address: liuyuehuiclark@21cn.com","institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5100751646"],"corresponding_institution_ids":["https://openalex.org/I141649914","https://openalex.org/I4210108480"],"apc_list":{"value":4340,"currency":"USD","value_usd":4340},"apc_paid":null,"fwci":10.0033,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.9914339,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"492","issue":null,"first_page":"138145","last_page":"138145"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.4207000136375427,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","score":0.4207000136375427,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.2897999882698059,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.15940000116825104,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pm2-5","display_name":"PM2.5","score":0.996999979019165},{"id":"https://openalex.org/keywords/allergic-rhinitis","display_name":"allergic rhinitis","score":0.9100000262260437},{"id":"https://openalex.org/keywords/pyroptosis","display_name":"pyroptosis","score":0.9419999718666077},{"id":"https://openalex.org/keywords/nlrp3-inflammasome","display_name":"NLRP3 inflammasome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/nasal-epithelial-barrier","display_name":"nasal epithelial barrier","score":0.8830000162124634},{"id":"https://openalex.org/keywords/aryl-hydrocarbon-receptor","display_name":"aryl hydrocarbon receptor","score":0.8519999980926514},{"id":"https://openalex.org/keywords/cyp1a1","display_name":"CYP1A1","score":0.9980000257492065},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":1.0},{"id":"https://openalex.org/keywords/tight-junctions","display_name":"tight junctions","score":0.8080000281333923},{"id":"https://openalex.org/keywords/air-pollution","display_name":"air pollution","score":0.9139999747276306},{"id":"https://openalex.org/keywords/respiratory-tract-inflammation","display_name":"respiratory inflammation","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C17172800","wikidata":"https://www.wikidata.org/wiki/Q7263707","display_name":"Pyroptosis","level":4,"score":0.8565024137496948},{"id":"https://openalex.org/C2991981033","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Skin barrier","level":2,"score":0.532103419303894},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.44348037242889404},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3819822669029236},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.36677223443984985},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3317767381668091},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.19252660870552063},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.1641843020915985},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12806513905525208},{"id":"https://openalex.org/C2777209026","wikidata":"https://www.wikidata.org/wiki/Q412405","display_name":"Inflammasome","level":3,"score":0.10615167021751404}],"mesh":[{"descriptor_ui":"D000069292","descriptor_name":"Pyroptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D000071199","descriptor_name":"NLR Family, Pyrin Domain-Containing 3 Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000393","descriptor_name":"Air Pollutants","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004847","descriptor_name":"Epithelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008807","descriptor_name":"Mice, Inbred BALB C","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D009297","descriptor_name":"Nasal Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018336","descriptor_name":"Receptors, Aryl Hydrocarbon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019363","descriptor_name":"Cytochrome P-450 CYP1A1","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019363","descriptor_name":"Cytochrome P-450 CYP1A1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051792","descriptor_name":"Basic Helix-Loop-Helix Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052638","descriptor_name":"Particulate Matter","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D065631","descriptor_name":"Rhinitis, Allergic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.jhazmat.2025.138145","doi":"https://doi.org/10.1016/j.jhazmat.2025.138145","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jhazmat.2025.138145","pdf_url":null,"source":{"id":"https://openalex.org/S145089992","display_name":"Journal of Hazardous Materials","issn_l":"0304-3894","issn":["0304-3894","1873-3336"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","jufo-3","ki-jl-2","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hazardous Materials","raw_type":"journal-article"},{"id":"pmid:40209413","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40209413","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of hazardous materials","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1518037388","display_name":null,"funder_award_id":"2023YNFY12007","funder_id":"https://openalex.org/F4320322792","funder_display_name":"Nanchang University"},{"id":"https://openalex.org/G1829738442","display_name":null,"funder_award_id":"O-IBR EC-2023\\u201379","funder_id":"https://openalex.org/F4320322792","funder_display_name":"Nanchang University"},{"id":"https://openalex.org/G4946794017","display_name":null,"funder_award_id":"20232BAB206078","funder_id":"https://openalex.org/F4320322665","funder_display_name":"Natural Science Foundation of Jiangxi Province"},{"id":"https://openalex.org/G5970788663","display_name":"miR-155-5p/TLE4\u8f74\u901a\u8fc7\u6fc0\u6d3bWnt/\u03b2-catenin\u4fe1\u53f7\u901a\u8def\u6d3b\u5316ILC2s\u8bf1\u53d1\u53d8\u5e94\u6027\u9f3b\u708e\u7684\u673a\u5236\u7814\u7a76","funder_award_id":"82060185","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6496964412","display_name":null,"funder_award_id":"20232BAB216058","funder_id":"https://openalex.org/F4320322665","funder_display_name":"Natural Science Foundation of Jiangxi Province"},{"id":"https://openalex.org/G6583159887","display_name":null,"funder_award_id":"20224BAB216050","funder_id":"https://openalex.org/F4320322665","funder_display_name":"Natural Science Foundation of Jiangxi Province"},{"id":"https://openalex.org/G7025913944","display_name":null,"funder_award_id":"2022YNFY12009","funder_id":"https://openalex.org/F4320322792","funder_display_name":"Nanchang University"},{"id":"https://openalex.org/G7933341442","display_name":null,"funder_award_id":"82360220","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8493994442","display_name":null,"funder_award_id":"NCULAE-20221031110","funder_id":"https://openalex.org/F4320322792","funder_display_name":"Nanchang University"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322665","display_name":"Natural Science Foundation of Jiangxi Province","ror":null},{"id":"https://openalex.org/F4320322792","display_name":"Nanchang University","ror":"https://ror.org/042v6xz23"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W1963815148","https://openalex.org/W2073875167","https://openalex.org/W2079882002","https://openalex.org/W2799533385","https://openalex.org/W2911968308","https://openalex.org/W2954047794","https://openalex.org/W2955367334","https://openalex.org/W2971739096","https://openalex.org/W2989859221","https://openalex.org/W2991339604","https://openalex.org/W2992180822","https://openalex.org/W2993565300","https://openalex.org/W3010269140","https://openalex.org/W3011404004","https://openalex.org/W3015735187","https://openalex.org/W3016194560","https://openalex.org/W3033954215","https://openalex.org/W3048947264","https://openalex.org/W3092718471","https://openalex.org/W3119977534","https://openalex.org/W3124277867","https://openalex.org/W3163009041","https://openalex.org/W3165301382","https://openalex.org/W3170082459","https://openalex.org/W3176332101","https://openalex.org/W3183974767","https://openalex.org/W3188184413","https://openalex.org/W3211414905","https://openalex.org/W3213770105","https://openalex.org/W3216001998","https://openalex.org/W3216721301","https://openalex.org/W4200450359","https://openalex.org/W4210575402","https://openalex.org/W4210607137","https://openalex.org/W4214820838","https://openalex.org/W4220653278","https://openalex.org/W4220822720","https://openalex.org/W4223574719","https://openalex.org/W4280623965","https://openalex.org/W4283217874","https://openalex.org/W4285243914","https://openalex.org/W4294001818","https://openalex.org/W4295519443","https://openalex.org/W4313593781","https://openalex.org/W4323921137","https://openalex.org/W4327571599","https://openalex.org/W4368371133","https://openalex.org/W4377819329","https://openalex.org/W4381848092","https://openalex.org/W4382359367","https://openalex.org/W4382361755","https://openalex.org/W4385219827","https://openalex.org/W4385872508","https://openalex.org/W4386318642","https://openalex.org/W4386456463","https://openalex.org/W4386568058","https://openalex.org/W4386725776","https://openalex.org/W4386941173","https://openalex.org/W4386947247","https://openalex.org/W4387493258","https://openalex.org/W4387597450","https://openalex.org/W4387910423","https://openalex.org/W4388947367","https://openalex.org/W4390615448","https://openalex.org/W4390910083","https://openalex.org/W4391515355","https://openalex.org/W4391932179","https://openalex.org/W4392816679","https://openalex.org/W4394770551","https://openalex.org/W4399222265","https://openalex.org/W4399796442","https://openalex.org/W4403348924"],"related_works":["https://openalex.org/W3211414905","https://openalex.org/W4409187106","https://openalex.org/W4416713510","https://openalex.org/W4411187299","https://openalex.org/W6903561989","https://openalex.org/W4417466368","https://openalex.org/W7169537391","https://openalex.org/W7140192079","https://openalex.org/W3183974767","https://openalex.org/W4385186959"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":36},{"year":2025,"cited_by_count":9}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2025-04-04T00:00:00"}