{"id":"https://openalex.org/W4409114683","doi":"https://doi.org/10.1158/0008-5472.28721669","title":"Table S1 from Targeting TUT1 Depletes Tri-snRNP Pools to Suppress Splicing and Inhibit Pancreatic Cancer Cell Survival","display_name":"Table S1 from Targeting TUT1 Depletes Tri-snRNP Pools to Suppress Splicing and Inhibit Pancreatic Cancer Cell Survival","publication_year":2025,"publication_date":"2025-04-03","ids":{"openalex":"https://openalex.org/W4409114683","doi":"https://doi.org/10.1158/0008-5472.28721669"},"language":"en","primary_location":{"id":"doi:10.1158/0008-5472.28721669","doi":"https://doi.org/10.1158/0008-5472.28721669","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.28721669","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"other","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/0008-5472.28721669","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101554490","display_name":"Ziwei Guo","orcid":"https://orcid.org/0000-0003-2357-259X","observed_orcids":["https://orcid.org/0000-0003-2357-259X","https://orcid.org/0009-0008-4107-1215"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ziwei Guo","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2357-259X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024839353","display_name":"Junran Huang","orcid":"https://orcid.org/0009-0000-9450-1954","observed_orcids":["https://orcid.org/0009-0000-9450-1954"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Junran Huang","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0000-9450-1954","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031246881","display_name":"Zhi John Lu","orcid":"https://orcid.org/0000-0003-4751-9400","observed_orcids":["https://orcid.org/0000-0003-4751-9400"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhi J. Lu","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4751-9400","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058898427","display_name":"Yongsheng Shi","orcid":"https://orcid.org/0000-0003-2967-1230","observed_orcids":["https://orcid.org/0000-0003-2967-1230","https://orcid.org/0009-0009-0164-8339"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yongsheng Shi","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-2967-1230","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070381062","display_name":"Charles J. David","orcid":"https://orcid.org/0000-0002-1257-8198","observed_orcids":["https://orcid.org/0000-0002-1257-8198"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles J. David","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1257-8198","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5100387252","display_name":"Mo Chen","orcid":"https://orcid.org/0000-0002-6647-8483","observed_orcids":["https://orcid.org/0000-0002-6647-8483","https://orcid.org/0000-0002-3274-5889"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mo Chen","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6647-8483","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9667999744415283,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.01730000041425228,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.007499999832361937,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tri-snrnp","display_name":"tri-snRNP","score":0.9020000100135803},{"id":"https://openalex.org/keywords/pre-mrna-splicing","display_name":"pre-mRNA splicing","score":0.8180000185966492},{"id":"https://openalex.org/keywords/rna-binding-proteins","display_name":"RNA-binding proteins","score":0.6869999766349792},{"id":"https://openalex.org/keywords/crispr-screening","display_name":"CRISPR screen","score":0.8669999837875366},{"id":"https://openalex.org/keywords/pancreatic-cancer","display_name":"pancreatic cancer","score":0.9509999752044678},{"id":"https://openalex.org/keywords/cell-survival","display_name":"cell survival","score":0.8330000042915344},{"id":"https://openalex.org/keywords/rna-modification","display_name":"RNA modification","score":0.3880000114440918}],"concepts":[{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.689082145690918},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.614240825176239},{"id":"https://openalex.org/C2780210213","wikidata":"https://www.wikidata.org/wiki/Q212961","display_name":"Pancreatic cancer","level":3,"score":0.5874860286712646},{"id":"https://openalex.org/C68483431","wikidata":"https://www.wikidata.org/wiki/Q2076770","display_name":"snRNP","level":5,"score":0.47922924160957336},{"id":"https://openalex.org/C45235069","wikidata":"https://www.wikidata.org/wiki/Q278425","display_name":"Table (database)","level":2,"score":0.45014482736587524},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3722023367881775},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.37022385001182556},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.36199578642845154},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2255958616733551},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.18898743391036987},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.1614719033241272},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.1577470898628235},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/0008-5472.28721669","doi":"https://doi.org/10.1158/0008-5472.28721669","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.28721669","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/28721669","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/dataset/Table_S1_from_Targeting_TUT1_Depletes_Tri-snRNP_Pools_to_Suppress_Splicing_and_Inhibit_Pancreatic_Cancer_Cell_Survival/28721669","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Dataset"}],"best_oa_location":{"id":"doi:10.1158/0008-5472.28721669","doi":"https://doi.org/10.1158/0008-5472.28721669","is_oa":true,"landing_page_url":"https://doi.org/10.1158/0008-5472.28721669","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6358000040054321,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7165005491","https://openalex.org/W7165057558","https://openalex.org/W7165019077","https://openalex.org/W4409114766","https://openalex.org/W7165001647","https://openalex.org/W7165025731","https://openalex.org/W4409114570","https://openalex.org/W7165041624","https://openalex.org/W4409114765","https://openalex.org/W4409114568"],"abstract_inverted_index":{"CRISPR":[0],"screening":[1],"of":[2],"RNA":[3],"binding":[4],"proteins":[5]},"counts_by_year":[],"updated_date":"2026-11-03T10:50:19.383937","created_date":"2025-04-03T00:00:00"}