{"id":"https://openalex.org/W4409092139","doi":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x","title":"Sympathoneural and Adrenomedullary Responses to Mental Stress","display_name":"Sympathoneural and Adrenomedullary Responses to Mental Stress","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W4409092139","doi":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x"},"language":"en","primary_location":{"id":"doi:10.1002/j.2040-4603.2015.tb00608.x","doi":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.2040-4603.2015.tb00608.x","source":{"id":"https://openalex.org/S18747983","display_name":"Comprehensive physiology","issn_l":"2040-4603","issn":["2040-4603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.2040-4603.2015.tb00608.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052142670","display_name":"Jason R. Carter","orcid":"https://orcid.org/0000-0001-7350-6537","observed_orcids":["https://orcid.org/0000-0001-7350-6537"]},"institutions":[{"id":"https://openalex.org/I11957088","display_name":"Michigan Technological University","ror":"https://ror.org/0036rpn28","country_code":"US","type":"education","lineage":["https://openalex.org/I11957088"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jason R. Carter","raw_affiliation_strings":["Department of Kinesiology and Integrative Physiology Michigan Technological University  Houghton Michigan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Kinesiology and Integrative Physiology Michigan Technological University  Houghton Michigan","institution_ids":["https://openalex.org/I11957088"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050003203","display_name":"David S. Goldstein","orcid":"https://orcid.org/0000-0002-5709-9940","observed_orcids":["https://orcid.org/0000-0002-5709-9940"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David S. Goldstein","raw_affiliation_strings":["Clinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research National Institutes of Health  Bethesda Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Neurocardiology Section, Clinical Neurosciences Program, Division of Intramural Research National Institutes of Health  Bethesda Maryland","institution_ids":["https://openalex.org/I1299303238"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5052142670"],"corresponding_institution_ids":["https://openalex.org/I11957088"],"apc_list":null,"apc_paid":null,"fwci":2.0835,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.84627093,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"5","issue":"1","first_page":"119","last_page":"146"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10529","display_name":"Stress Responses and Cortisol","score":0.9179999828338623,"subfield":{"id":"https://openalex.org/subfields/2802","display_name":"Behavioral Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.07559999823570251,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12082","display_name":"Takotsubo Cardiomyopathy and Associated Phenomena","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/psychological-stress","display_name":"psychological stress","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sympathoadrenal-system","display_name":"sympathoadrenal system","score":0.9860000014305115},{"id":"https://openalex.org/keywords/catecholaminergic-system","display_name":"catecholaminergic system","score":0.8080000281333923},{"id":"https://openalex.org/keywords/allostasis","display_name":"allostasis","score":0.9240000247955322},{"id":"https://openalex.org/keywords/allostatic-load","display_name":"allostatic load","score":0.9990000128746033},{"id":"https://openalex.org/keywords/homeostasis","display_name":"homeostasis","score":0.8519999980926514},{"id":"https://openalex.org/keywords/stress-reactivity","display_name":"stress reactivity","score":0.4970000088214874},{"id":"https://openalex.org/keywords/psychoneuroimmunology","display_name":"psychoneuroimmunology","score":0.7039999961853027}],"concepts":[{"id":"https://openalex.org/C2984493583","wikidata":"https://www.wikidata.org/wiki/Q3500368","display_name":"Mental stress","level":2,"score":0.5192806124687195},{"id":"https://openalex.org/C21036866","wikidata":"https://www.wikidata.org/wiki/Q181767","display_name":"Stress (linguistics)","level":2,"score":0.4198862910270691},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.36656010150909424},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.34796974062919617},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27230411767959595},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24042508006095886},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.08724528551101685},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/j.2040-4603.2015.tb00608.x","doi":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.2040-4603.2015.tb00608.x","source":{"id":"https://openalex.org/S18747983","display_name":"Comprehensive physiology","issn_l":"2040-4603","issn":["2040-4603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/j.2040-4603.2015.tb00608.x","doi":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.2040-4603.2015.tb00608.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.2040-4603.2015.tb00608.x","source":{"id":"https://openalex.org/S18747983","display_name":"Comprehensive physiology","issn_l":"2040-4603","issn":["2040-4603"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-200","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Comprehensive Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8048999905586243,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4409092139.pdf","grobid_xml":"https://content.openalex.org/works/W4409092139.grobid-xml"},"referenced_works_count":295,"referenced_works":["https://openalex.org/W2672651","https://openalex.org/W17021510","https://openalex.org/W28261467","https://openalex.org/W31583094","https://openalex.org/W76314274","https://openalex.org/W163901654","https://openalex.org/W175006040","https://openalex.org/W192583731","https://openalex.org/W1026910736","https://openalex.org/W1178598793","https://openalex.org/W1485647639","https://openalex.org/W1508148070","https://openalex.org/W1566506783","https://openalex.org/W1581754489","https://openalex.org/W1607171655","https://openalex.org/W1729896994","https://openalex.org/W1764638724","https://openalex.org/W1864899974","https://openalex.org/W1905255146","https://openalex.org/W1947237304","https://openalex.org/W1963735974","https://openalex.org/W1963984360","https://openalex.org/W1964083072","https://openalex.org/W1964117449","https://openalex.org/W1964333225","https://openalex.org/W1964612682","https://openalex.org/W1964713838","https://openalex.org/W1964972447","https://openalex.org/W1965486589","https://openalex.org/W1966158684","https://openalex.org/W1966317112","https://openalex.org/W1966538209","https://openalex.org/W1967487265","https://openalex.org/W1968826589","https://openalex.org/W1969406390","https://openalex.org/W1969800465","https://openalex.org/W1970105912","https://openalex.org/W1970643432","https://openalex.org/W1971922508","https://openalex.org/W1973141007","https://openalex.org/W1973379750","https://openalex.org/W1973801497","https://openalex.org/W1974127453","https://openalex.org/W1976875134","https://openalex.org/W1976877150","https://openalex.org/W1977574579","https://openalex.org/W1978445312","https://openalex.org/W1978743977","https://openalex.org/W1980196787","https://openalex.org/W1980427432","https://openalex.org/W1983016050","https://openalex.org/W1984909793","https://openalex.org/W1985712169","https://openalex.org/W1990504544","https://openalex.org/W1990787873","https://openalex.org/W1990797163","https://openalex.org/W1991054913","https://openalex.org/W1991852456","https://openalex.org/W1994025355","https://openalex.org/W1994487234","https://openalex.org/W1996476986","https://openalex.org/W1997971323","https://openalex.org/W1998178566","https://openalex.org/W1999925228","https://openalex.org/W2001062140","https://openalex.org/W2001533142","https://openalex.org/W2002765069","https://openalex.org/W2002802041","https://openalex.org/W2002932114","https://openalex.org/W2003400453","https://openalex.org/W2003444189","https://openalex.org/W2004988120","https://openalex.org/W2007411824","https://openalex.org/W2008209670","https://openalex.org/W2009051828","https://openalex.org/W2011850787","https://openalex.org/W2013784101","https://openalex.org/W2016944059","https://openalex.org/W2019099892","https://openalex.org/W2019763876","https://openalex.org/W2020782993","https://openalex.org/W2021463223","https://openalex.org/W2021609092","https://openalex.org/W2022294968","https://openalex.org/W2023567744","https://openalex.org/W2024738751","https://openalex.org/W2024924310","https://openalex.org/W2025483550","https://openalex.org/W2028918510","https://openalex.org/W2029410796","https://openalex.org/W2029952142","https://openalex.org/W2032060045","https://openalex.org/W2034118231","https://openalex.org/W2036424780","https://openalex.org/W2036509736","https://openalex.org/W2037377721","https://openalex.org/W2038476114","https://openalex.org/W2039623117","https://openalex.org/W2039981344","https://openalex.org/W2039998405","https://openalex.org/W2041259731","https://openalex.org/W2041502906","https://openalex.org/W2042169383","https://openalex.org/W2043248763","https://openalex.org/W2047474099","https://openalex.org/W2048060485","https://openalex.org/W2049211744","https://openalex.org/W2049607533","https://openalex.org/W2049831470","https://openalex.org/W2050134733","https://openalex.org/W2050193820","https://openalex.org/W2052820708","https://openalex.org/W2053741430","https://openalex.org/W2053936534","https://openalex.org/W2053936809","https://openalex.org/W2053965426","https://openalex.org/W2056668609","https://openalex.org/W2058021195","https://openalex.org/W2058469386","https://openalex.org/W2060661592","https://openalex.org/W2061628754","https://openalex.org/W2062917118","https://openalex.org/W2063576068","https://openalex.org/W2064160066","https://openalex.org/W2064173030","https://openalex.org/W2064366151","https://openalex.org/W2064412622","https://openalex.org/W2064579956","https://openalex.org/W2067551902","https://openalex.org/W2068239827","https://openalex.org/W2069455631","https://openalex.org/W2070914040","https://openalex.org/W2070968795","https://openalex.org/W2071647073","https://openalex.org/W2072684136","https://openalex.org/W2073676074","https://openalex.org/W2075988974","https://openalex.org/W2078464991","https://openalex.org/W2078508854","https://openalex.org/W2079498505","https://openalex.org/W2081791066","https://openalex.org/W2082433653","https://openalex.org/W2082567556","https://openalex.org/W2084457825","https://openalex.org/W2085122454","https://openalex.org/W2085461277","https://openalex.org/W2086280495","https://openalex.org/W2087704790","https://openalex.org/W2087873471","https://openalex.org/W2088590019","https://openalex.org/W2089136242","https://openalex.org/W2089652976","https://openalex.org/W2092238207","https://openalex.org/W2092317032","https://openalex.org/W2092630217","https://openalex.org/W2092862425","https://openalex.org/W2094280561","https://openalex.org/W2094284063","https://openalex.org/W2094461980","https://openalex.org/W2095245820","https://openalex.org/W2096967454","https://openalex.org/W2098755321","https://openalex.org/W2098814002","https://openalex.org/W2100734162","https://openalex.org/W2104874494","https://openalex.org/W2105480884","https://openalex.org/W2107879738","https://openalex.org/W2108617039","https://openalex.org/W2109106796","https://openalex.org/W2109523093","https://openalex.org/W2111810521","https://openalex.org/W2111986556","https://openalex.org/W2112648950","https://openalex.org/W2113504992","https://openalex.org/W2113621206","https://openalex.org/W2114382841","https://openalex.org/W2114966243","https://openalex.org/W2115461708","https://openalex.org/W2115683394","https://openalex.org/W2115884349","https://openalex.org/W2116246049","https://openalex.org/W2119692628","https://openalex.org/W2119926473","https://openalex.org/W2120416826","https://openalex.org/W2122580458","https://openalex.org/W2124516234","https://openalex.org/W2128259854","https://openalex.org/W2128427462","https://openalex.org/W2128485376","https://openalex.org/W2129791845","https://openalex.org/W2129873269","https://openalex.org/W2129992572","https://openalex.org/W2130224299","https://openalex.org/W2132065933","https://openalex.org/W2132269475","https://openalex.org/W2132800736","https://openalex.org/W2134083741","https://openalex.org/W2134409991","https://openalex.org/W2135315072","https://openalex.org/W2136115725","https://openalex.org/W2137214610","https://openalex.org/W2137283361","https://openalex.org/W2137335941","https://openalex.org/W2138399442","https://openalex.org/W2138479470","https://openalex.org/W2138788197","https://openalex.org/W2140376832","https://openalex.org/W2142349354","https://openalex.org/W2143058377","https://openalex.org/W2143237504","https://openalex.org/W2143773886","https://openalex.org/W2145377878","https://openalex.org/W2145524929","https://openalex.org/W2145562384","https://openalex.org/W2146545384","https://openalex.org/W2146592576","https://openalex.org/W2147306819","https://openalex.org/W2147523013","https://openalex.org/W2148593775","https://openalex.org/W2148841524","https://openalex.org/W2149866596","https://openalex.org/W2153115306","https://openalex.org/W2153666922","https://openalex.org/W2153871458","https://openalex.org/W2155552942","https://openalex.org/W2157340456","https://openalex.org/W2159018920","https://openalex.org/W2159580288","https://openalex.org/W2159759077","https://openalex.org/W2160306857","https://openalex.org/W2160535929","https://openalex.org/W2160653940","https://openalex.org/W2160803495","https://openalex.org/W2161076481","https://openalex.org/W2162521425","https://openalex.org/W2163613769","https://openalex.org/W2164300039","https://openalex.org/W2164509516","https://openalex.org/W2165558339","https://openalex.org/W2166104887","https://openalex.org/W2166624057","https://openalex.org/W2167611756","https://openalex.org/W2167780664","https://openalex.org/W2168675611","https://openalex.org/W2171081455","https://openalex.org/W2173593532","https://openalex.org/W2175243815","https://openalex.org/W2203599354","https://openalex.org/W2230990971","https://openalex.org/W2263635164","https://openalex.org/W2283505034","https://openalex.org/W2294888261","https://openalex.org/W2297098890","https://openalex.org/W2298257631","https://openalex.org/W2305099924","https://openalex.org/W2313133515","https://openalex.org/W2317356102","https://openalex.org/W2318067072","https://openalex.org/W2319818054","https://openalex.org/W2321321837","https://openalex.org/W2321624043","https://openalex.org/W2325791828","https://openalex.org/W2327604823","https://openalex.org/W2337472110","https://openalex.org/W2339871793","https://openalex.org/W2377496017","https://openalex.org/W2394779432","https://openalex.org/W2403949634","https://openalex.org/W2411497311","https://openalex.org/W2413229256","https://openalex.org/W2414260606","https://openalex.org/W2415684478","https://openalex.org/W2417652376","https://openalex.org/W2418924049","https://openalex.org/W2428470344","https://openalex.org/W2438471694","https://openalex.org/W2467626682","https://openalex.org/W2472437662","https://openalex.org/W2529489274","https://openalex.org/W2606243228","https://openalex.org/W2612761910","https://openalex.org/W2617589934","https://openalex.org/W2625400966","https://openalex.org/W2807125633","https://openalex.org/W4230649639","https://openalex.org/W4234501352","https://openalex.org/W4234515901","https://openalex.org/W4237546140","https://openalex.org/W4237658773","https://openalex.org/W4241839580","https://openalex.org/W4245933202","https://openalex.org/W4254465727","https://openalex.org/W4292994367","https://openalex.org/W4294536004","https://openalex.org/W4409095738"],"related_works":["https://openalex.org/W2067561520","https://openalex.org/W2089634855","https://openalex.org/W2461039692","https://openalex.org/W2292801034","https://openalex.org/W2326016407","https://openalex.org/W4409122778","https://openalex.org/W4238337530","https://openalex.org/W7098530699","https://openalex.org/W2061628754","https://openalex.org/W259748061"],"abstract_inverted_index":{"Abstract":[0],"This":[1,56],"concept\u2010based":[2],"review":[3,23],"provides":[4],"historical":[5],"perspectives":[6],"and":[7,12,35,49,66,73,83,110,124,129],"updates":[8],"about":[9],"sympathetic":[10,13],"noradrenergic":[11],"adrenergic":[14],"responses":[15,99],"to":[16,90,100],"mental":[17,60,79,101],"stress.":[18],"The":[19,42],"topic":[20],"of":[21,29,38,71,78,104,117],"this":[22,132],"has":[24],"incited":[25],"perennial":[26],"debate,":[27],"because":[28],"disagreements":[30],"over":[31],"definitions,":[32],"controversial":[33],"inferences,":[34],"limited":[36],"availability":[37],"relevant":[39],"measurement":[40],"tools.":[41],"discussion":[43],"begins":[44],"appropriately":[45],"with":[46,87],"Cannon's":[47],"\u201chomeostasis\u201d":[48],"his":[50],"pioneering":[51],"work":[52],"in":[53,81,93],"the":[54,67,111,118],"area.":[55],"is":[57],"followed":[58],"by":[59],"stress":[61,80],"as":[62],"a":[63],"scientific":[64],"idea":[65],"relatively":[68],"new":[69],"notions":[70],"allostasis":[72],"allostatic":[74],"load.":[75],"Experimental":[76],"models":[77],"rodents":[82],"humans":[84],"are":[85],"discussed,":[86],"particular":[88],"attention":[89],"ethical":[91],"constraints":[92],"humans.":[94],"Sections":[95],"follow":[96],"on":[97,131],"sympathoneural":[98],"stress,":[102],"reactivity":[103,113],"catecholamine":[105],"systems,":[106],"clinical":[107],"pathophysiologic":[108],"states,":[109],"cardiovascular":[112],"hypothesis.":[114],"Future":[115],"advancement":[116],"field":[119],"will":[120],"require":[121],"integrative":[122],"approaches":[123],"coordinated":[125],"efforts":[126],"between":[127],"physiologists":[128],"psychologists":[130],"interdisciplinary":[133],"topic.":[134],"Published":[135],"2015.":[136,140],"Compr":[137],"Physiol":[138],"5:119\u2010146,":[139]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":7},{"year":2023,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2025-04-02T00:00:00"}