{"id":"https://openalex.org/W4409079601","doi":"https://doi.org/10.1158/1535-7163.28713861","title":"Supplemental Data File S1 from VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity","display_name":"Supplemental Data File S1 from VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity","publication_year":2025,"publication_date":"2025-04-02","ids":{"openalex":"https://openalex.org/W4409079601","doi":"https://doi.org/10.1158/1535-7163.28713861"},"language":"en","primary_location":{"id":"doi:10.1158/1535-7163.28713861","doi":"https://doi.org/10.1158/1535-7163.28713861","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.28713861","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1158/1535-7163.28713861","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006903694","display_name":"Kinsey L. Nelson","orcid":"https://orcid.org/0000-0003-4292-7325","observed_orcids":["https://orcid.org/0000-0003-4292-7325"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kinsey L. Nelson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4292-7325","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076451685","display_name":"Katherine A. Reil","orcid":"https://orcid.org/0000-0002-0255-6315","observed_orcids":["https://orcid.org/0000-0002-0255-6315"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katherine A. Reil","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0255-6315","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060389174","display_name":"Shingo Tsuji","orcid":"https://orcid.org/0000-0003-0598-3694","observed_orcids":["https://orcid.org/0000-0003-0598-3694"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shingo Tsuji","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0598-3694","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113034451","display_name":"Amanda M. Parikh","orcid":"https://orcid.org/0009-0002-2391-3622","observed_orcids":["https://orcid.org/0009-0002-2391-3622"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amanda M. Parikh","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-2391-3622","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021979414","display_name":"Mikella Robinson","orcid":"https://orcid.org/0000-0001-6198-7185","observed_orcids":["https://orcid.org/0000-0001-6198-7185"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mikella Robinson","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6198-7185","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059436422","display_name":"Carrie Danielle House","orcid":"https://orcid.org/0000-0002-1870-5872","observed_orcids":["https://orcid.org/0000-0002-1870-5872"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carrie D. House","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1870-5872","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055383437","display_name":"Kathleen L. McGuire","orcid":"https://orcid.org/0000-0002-5357-3721","observed_orcids":["https://orcid.org/0000-0002-5357-3721"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathleen L. McGuire","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-5357-3721","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5068096782","display_name":"Matthew J. Giacalone","orcid":"https://orcid.org/0000-0001-8979-115X","observed_orcids":["https://orcid.org/0000-0001-8979-115X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew J. Giacalone","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8979-115X","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.46799999475479126,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.46799999475479126,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.31029999256134033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.20399999618530273,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sting","display_name":"STING","score":0.8669999837875366},{"id":"https://openalex.org/keywords/rig-i","display_name":"RIG-I","score":1.0},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.9179999828338623},{"id":"https://openalex.org/keywords/cancer-vaccines","display_name":"cancer vaccines","score":0.4050000011920929},{"id":"https://openalex.org/keywords/innate-immune-activation","display_name":"innate immune activation","score":0.36000001430511475}],"concepts":[{"id":"https://openalex.org/C2779300339","wikidata":"https://www.wikidata.org/wiki/Q7617409","display_name":"Sting","level":2,"score":0.7652943730354309},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.5868387222290039},{"id":"https://openalex.org/C2776954689","wikidata":"https://www.wikidata.org/wiki/Q21100537","display_name":"RIG-I","level":4,"score":0.42304131388664246},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33649542927742004},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.33031338453292847},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.3263404369354248},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2175806760787964},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2105298936367035},{"id":"https://openalex.org/C146978453","wikidata":"https://www.wikidata.org/wiki/Q3798668","display_name":"Aerospace engineering","level":1,"score":0.08948549628257751}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1158/1535-7163.28713861","doi":"https://doi.org/10.1158/1535-7163.28713861","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.28713861","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"doi:10.1158/1535-7163.32709646","doi":"https://doi.org/10.1158/1535-7163.32709646","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.32709646","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/28713861","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplemental_Data_File_S1_from_VAX014_Activates_Tumor-Intrinsic_STING_and_RIG-I_to_Promote_the_Development_of_Antitumor_Immunity/28713861","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:figshare.com:article/32709646","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplemental_Data_File_S1_from_VAX014_Activates_Tumor-Intrinsic_STING_and_RIG-I_to_Promote_the_Development_of_Antitumor_Immunity/32709646","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1535-7163.28713861","doi":"https://doi.org/10.1158/1535-7163.28713861","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1535-7163.28713861","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4406842676","https://openalex.org/W4404052715","https://openalex.org/W3145688111"],"abstract_inverted_index":{"Full":[0],"Western":[1],"blot":[2],"images":[3]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2025-04-02T00:00:00"}