{"id":"https://openalex.org/W4408973585","doi":"https://doi.org/10.1007/978-3-031-82435-7_32","title":"Cell Signaling Characterization for Spatial Transcriptomics (ST) Data Using Network Analysis","display_name":"Cell Signaling Characterization for Spatial Transcriptomics (ST) Data Using Network Analysis","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4408973585","doi":"https://doi.org/10.1007/978-3-031-82435-7_32","pmid":"https://pubmed.ncbi.nlm.nih.gov/40510773","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12160023"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-031-82435-7_32","doi":"https://doi.org/10.1007/978-3-031-82435-7_32","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-82435-7_32","pdf_url":null,"source":{"id":"https://openalex.org/S2764461748","display_name":"Studies in computational intelligence","issn_l":"1860-949X","issn":["1860-949X","1860-9503"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Computational Intelligence","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4408973686","display_name":"Complex Networks & Their Applications XIII"},"type":"conference-paper","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12160023/pdf/nihms-2083842.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Azka Javaid","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Azka Javaid","raw_affiliation_strings":["Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA","institution_ids":["https://openalex.org/I107672454"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080933903","display_name":"Hildreth Robert Frost","orcid":"https://orcid.org/0000-0002-6794-9945","observed_orcids":["https://orcid.org/0000-0002-6794-9945"]},"institutions":[{"id":"https://openalex.org/I107672454","display_name":"Dartmouth College","ror":"https://ror.org/049s0rh22","country_code":"US","type":"education","lineage":["https://openalex.org/I107672454"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H. Robert Frost","raw_affiliation_strings":["Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Data Science, Geisel School of Medicine, Dartmouth College, Hanover, NH 03755, USA","institution_ids":["https://openalex.org/I107672454"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I107672454"],"apc_list":null,"apc_paid":null,"fwci":2.5689,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.88451139,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"1189","issue":null,"first_page":"394","last_page":"405"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/intercellular-communication","display_name":"intercellular communication","score":0.8190000057220459},{"id":"https://openalex.org/keywords/spatial-transcriptomics","display_name":"spatial transcriptomics","score":0.8880000114440918},{"id":"https://openalex.org/keywords/ligand-receptor-interactions","display_name":"ligand-receptor interactions","score":0.9319999814033508},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"signal transduction","score":0.7519999742507935},{"id":"https://openalex.org/keywords/network-analysis","display_name":"network analysis","score":0.593999981880188},{"id":"https://openalex.org/keywords/weighted-directed-networks","display_name":"directed weighted networks","score":0.652999997138977},{"id":"https://openalex.org/keywords/in-degree-centrality","display_name":"in-degree centrality","score":0.9829999804496765},{"id":"https://openalex.org/keywords/low-dimensional-embedding","display_name":"low-dimensional embedding","score":0.6320000290870667},{"id":"https://openalex.org/keywords/gene-expression-heterogeneity","display_name":"gene expression heterogeneity","score":0.6769999861717224}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5433699488639832},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.5407599806785583},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5045706033706665},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.43814677000045776},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3381185531616211},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2572714686393738},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09650307893753052},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0962277352809906},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.07897055149078369},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/978-3-031-82435-7_32","doi":"https://doi.org/10.1007/978-3-031-82435-7_32","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-82435-7_32","pdf_url":null,"source":{"id":"https://openalex.org/S2764461748","display_name":"Studies in computational intelligence","issn_l":"1860-949X","issn":["1860-949X","1860-9503"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Computational Intelligence","raw_type":"book-chapter"},{"id":"pmid:40510773","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40510773","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Complex networks & their applications. International Conference on Complex Networks and Their Applications","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12160023","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12160023","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12160023/pdf/nihms-2083842.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Complex Netw Appl XIII (2024)","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12160023","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12160023","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12160023/pdf/nihms-2083842.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Complex Netw Appl XIII (2024)","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2863533589","display_name":null,"funder_award_id":"R21 CA253408","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G6563202065","display_name":"Quantitative Biology Research Institute","funder_award_id":"P20GM103534","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G7000740400","display_name":"Cancer-specific gene set testing","funder_award_id":"1r21ca253408-01","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000859653","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA023108","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000867420","display_name":"Gene set analysis of single cell genomics","funder_award_id":"R35GM146586","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4408973585.pdf","grobid_xml":"https://content.openalex.org/works/W4408973585.grobid-xml"},"referenced_works_count":28,"referenced_works":["https://openalex.org/W1982482145","https://openalex.org/W2000822014","https://openalex.org/W2004827507","https://openalex.org/W2017904964","https://openalex.org/W2028771127","https://openalex.org/W2069089843","https://openalex.org/W2093150435","https://openalex.org/W2471536144","https://openalex.org/W2488424576","https://openalex.org/W2794446484","https://openalex.org/W2794480084","https://openalex.org/W2949177718","https://openalex.org/W2949471597","https://openalex.org/W2992151131","https://openalex.org/W3007935255","https://openalex.org/W3113349968","https://openalex.org/W3132661792","https://openalex.org/W3134482219","https://openalex.org/W3164692211","https://openalex.org/W3165868790","https://openalex.org/W3202418805","https://openalex.org/W4288758477","https://openalex.org/W4317757307","https://openalex.org/W4378212544","https://openalex.org/W4380630598","https://openalex.org/W4387697224","https://openalex.org/W4391746533","https://openalex.org/W4392748138"],"related_works":["https://openalex.org/W4409660862","https://openalex.org/W4283773897","https://openalex.org/W4392748138","https://openalex.org/W4408300361","https://openalex.org/W3192700451","https://openalex.org/W7163010629","https://openalex.org/W4312094047","https://openalex.org/W4288758477","https://openalex.org/W7151750368","https://openalex.org/W7222578868"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2025-03-30T00:00:00"}