{"id":"https://openalex.org/W4408934029","doi":"https://doi.org/10.1016/j.sciaf.2025.e02668","title":"Characterization of Chitosan/ Zeolite drug delivery composite and curcumin release kinetics in a simulated pH environment","display_name":"Characterization of Chitosan/ Zeolite drug delivery composite and curcumin release kinetics in a simulated pH environment","publication_year":2025,"publication_date":"2025-03-28","ids":{"openalex":"https://openalex.org/W4408934029","doi":"https://doi.org/10.1016/j.sciaf.2025.e02668"},"language":"en","primary_location":{"id":"doi:10.1016/j.sciaf.2025.e02668","doi":"https://doi.org/10.1016/j.sciaf.2025.e02668","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.sciaf.2025.e02668","pdf_url":null,"source":{"id":"https://openalex.org/S4210198261","display_name":"Scientific African","issn_l":"2468-2276","issn":["2468-2276"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific African","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.sciaf.2025.e02668","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020359550","display_name":"Gloria Pokuaa Manu","orcid":"https://orcid.org/0000-0002-0173-9531","observed_orcids":["https://orcid.org/0000-0002-0173-9531"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":true,"raw_author_name":"Gloria Pokuaa Manu","raw_affiliation_strings":["Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, Ghana","Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana"],"raw_orcid":"https://orcid.org/0000-0002-0173-9531","affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Cell and Molecular Biology, University of Ghana, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]},{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5096170555","display_name":"Daniel Narh","orcid":"https://orcid.org/0009-0008-3076-4606","observed_orcids":["https://orcid.org/0009-0008-3076-4606"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Daniel Narh","raw_affiliation_strings":["Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana"],"raw_orcid":"https://orcid.org/0009-0008-3076-4606","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046694115","display_name":"Bernard Owusu Asimeng","orcid":"https://orcid.org/0000-0002-4847-450X","observed_orcids":["https://orcid.org/0000-0002-4847-450X"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Bernard Asimeng","raw_affiliation_strings":["Department of Biomedical Engineering, University of Ghana, LG 56, Accra, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, University of Ghana, LG 56, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116833793","display_name":"Nadesh Kwakye","orcid":"https://orcid.org/0009-0007-9804-2872","observed_orcids":["https://orcid.org/0009-0007-9804-2872"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Nadesh Kwakye","raw_affiliation_strings":["Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana"],"raw_orcid":"https://orcid.org/0009-0007-9804-2872","affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116833794","display_name":"Barbara Ansaah Abusuapa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Barbara Ansaah Abusuapa","raw_affiliation_strings":["Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116833795","display_name":"Daniel Appuing","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Daniel Appuing","raw_affiliation_strings":["Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065765515","display_name":"Emmanuel Nyankson","orcid":"https://orcid.org/0000-0001-7041-3466","observed_orcids":["https://orcid.org/0000-0001-7041-3466"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Emmanuel Nyankson","raw_affiliation_strings":["Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013244147","display_name":"J.K. Efavi","orcid":"https://orcid.org/0000-0002-9809-533X","observed_orcids":["https://orcid.org/0000-0002-9809-533X"]},"institutions":[{"id":"https://openalex.org/I138690464","display_name":"University of Ghana","ror":"https://ror.org/01r22mr83","country_code":"GH","type":"education","lineage":["https://openalex.org/I138690464"]}],"countries":["GH"],"is_corresponding":false,"raw_author_name":"Johnson K. Efavi","raw_affiliation_strings":["Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Materials Science and Engineering, University of Ghana, LG 77, Accra, Ghana","institution_ids":["https://openalex.org/I138690464"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5020359550"],"corresponding_institution_ids":["https://openalex.org/I138690464"],"apc_list":{"value":590,"currency":"USD","value_usd":590},"apc_paid":{"value":590,"currency":"USD","value_usd":590},"fwci":4.7354,"has_fulltext":false,"cited_by_count":14,"citation_normalized_percentile":{"value":0.95589631,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"28","issue":null,"first_page":"e02668","last_page":"e02668"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.8270999789237976,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.8270999789237976,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.09210000187158585,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.039000000804662704,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/curcumin","display_name":"curcumin","score":0.9670000076293945},{"id":"https://openalex.org/keywords/drug-release-kinetics","display_name":"drug release kinetics","score":0.7590000033378601},{"id":"https://openalex.org/keywords/sustained-release","display_name":"sustained drug release","score":0.8240000009536743},{"id":"https://openalex.org/keywords/ph-responsive-drug-release","display_name":"pH-responsive drug release","score":0.5490000247955322},{"id":"https://openalex.org/keywords/anticancer-drug-delivery","display_name":"anticancer drug delivery","score":0.7919999957084656},{"id":"https://openalex.org/keywords/higuchi-kinetics","display_name":"Higuchi model","score":0.7089999914169312},{"id":"https://openalex.org/keywords/fickian-diffusion","display_name":"Fickian diffusion","score":0.8180000185966492},{"id":"https://openalex.org/keywords/encapsulation-efficiency","display_name":"encapsulation efficiency","score":0.859000027179718},{"id":"https://openalex.org/keywords/zeolite-functionalization","display_name":"zeolite functionalization","score":0.8799999952316284}],"concepts":[{"id":"https://openalex.org/C2779732960","wikidata":"https://www.wikidata.org/wiki/Q408510","display_name":"Chitosan","level":2,"score":0.8563941717147827},{"id":"https://openalex.org/C2778250585","wikidata":"https://www.wikidata.org/wiki/Q312266","display_name":"Curcumin","level":2,"score":0.8069264888763428},{"id":"https://openalex.org/C148898269","wikidata":"https://www.wikidata.org/wiki/Q1108792","display_name":"Kinetics","level":2,"score":0.6897112727165222},{"id":"https://openalex.org/C2778077586","wikidata":"https://www.wikidata.org/wiki/Q181332","display_name":"Zeolite","level":3,"score":0.6693791747093201},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.6544906497001648},{"id":"https://openalex.org/C2779820397","wikidata":"https://www.wikidata.org/wiki/Q1392806","display_name":"Drug delivery","level":2,"score":0.6290198564529419},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.554186999797821},{"id":"https://openalex.org/C104779481","wikidata":"https://www.wikidata.org/wiki/Q50707","display_name":"Composite number","level":2,"score":0.5481396913528442},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.5019617080688477},{"id":"https://openalex.org/C163588942","wikidata":"https://www.wikidata.org/wiki/Q5165929","display_name":"Controlled release","level":2,"score":0.4699331223964691},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4297493100166321},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.33823996782302856},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3206893801689148},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.21462810039520264},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.202815443277359},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.1487894356250763},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.10903969407081604},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10177692770957947},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07409414649009705},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.06711548566818237},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0431637167930603},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1016/j.sciaf.2025.e02668","doi":"https://doi.org/10.1016/j.sciaf.2025.e02668","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.sciaf.2025.e02668","pdf_url":null,"source":{"id":"https://openalex.org/S4210198261","display_name":"Scientific African","issn_l":"2468-2276","issn":["2468-2276"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific African","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:9268ab28d4e94c8c9309ac2d6f81cf1c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/9268ab28d4e94c8c9309ac2d6f81cf1c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific African, Vol 28, Iss , Pp e02668- (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.sciaf.2025.e02668","doi":"https://doi.org/10.1016/j.sciaf.2025.e02668","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.sciaf.2025.e02668","pdf_url":null,"source":{"id":"https://openalex.org/S4210198261","display_name":"Scientific African","issn_l":"2468-2276","issn":["2468-2276"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","norway-1","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific African","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Zero hunger","score":0.41999998688697815,"id":"https://metadata.un.org/sdg/2"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1420516430","https://openalex.org/W1494121972","https://openalex.org/W1604068141","https://openalex.org/W1845739782","https://openalex.org/W1968832304","https://openalex.org/W1976194786","https://openalex.org/W2001852846","https://openalex.org/W2004010748","https://openalex.org/W2005433498","https://openalex.org/W2007492343","https://openalex.org/W2010567530","https://openalex.org/W2015409273","https://openalex.org/W2017916544","https://openalex.org/W2039451560","https://openalex.org/W2041764058","https://openalex.org/W2044261006","https://openalex.org/W2047925917","https://openalex.org/W2048776167","https://openalex.org/W2049077338","https://openalex.org/W2057760381","https://openalex.org/W2076580808","https://openalex.org/W2103647191","https://openalex.org/W2113376388","https://openalex.org/W2117630026","https://openalex.org/W2118120380","https://openalex.org/W2145706118","https://openalex.org/W2339737145","https://openalex.org/W2472639786","https://openalex.org/W2503407456","https://openalex.org/W2503602835","https://openalex.org/W2567524659","https://openalex.org/W2606444228","https://openalex.org/W2734687544","https://openalex.org/W2742828015","https://openalex.org/W2788242373","https://openalex.org/W2883514196","https://openalex.org/W2901988599","https://openalex.org/W2918800693","https://openalex.org/W2919672145","https://openalex.org/W2936466437","https://openalex.org/W2960698964","https://openalex.org/W2961946656","https://openalex.org/W2967813269","https://openalex.org/W2978605903","https://openalex.org/W3000620731","https://openalex.org/W3000634186","https://openalex.org/W3006327886","https://openalex.org/W3019117118","https://openalex.org/W3080650814","https://openalex.org/W3093273025","https://openalex.org/W3102983191","https://openalex.org/W3207127863","https://openalex.org/W4238410074","https://openalex.org/W4297229503","https://openalex.org/W4306840209","https://openalex.org/W4312195182","https://openalex.org/W4323664572"],"related_works":["https://openalex.org/W2589512255","https://openalex.org/W2887769962","https://openalex.org/W4379468034","https://openalex.org/W4408884021","https://openalex.org/W1984122016","https://openalex.org/W2117116660","https://openalex.org/W1971462710","https://openalex.org/W2948758012","https://openalex.org/W2043425471","https://openalex.org/W2336156617"],"abstract_inverted_index":{"\u2022":[0,9,19,30],"Chitosan/zeolite":[1,10,20],"nanocomposite":[2,11,21,70,91,145,240],"represents":[3],"an":[4,210],"effective":[5,52],"drug":[6,53,108,140,168,181,250,254],"delivery":[7,54,72,169],"platform.":[8],"efficiently":[12],"entrapped":[13],"curcumin,":[14,153,222],"a":[15,23,43,68,147,224,245],"potential":[16,156],"anticancer":[17],"drug.":[18],"provided":[22],"controlled":[24],"and":[25,32,85,107,116,149,195,256],"sustained":[26,150],"release":[27,34,65,125,141,151,184,205,220],"of":[28,67,127,152,165,207,221,227],"curcumin.":[29,75,88],"Stable":[31],"enhanced":[33,249],"profiles":[35],"observed":[36],"in":[37,132,179],"simulated":[38,133],"pH":[39,134],"environment.":[40],"Cancer":[41],"remains":[42],"formidable":[44],"global":[45],"health":[46],"challenge,":[47],"necessitating":[48],"innovative":[49],"strategies":[50],"for":[51,94,157,248],"to":[55],"tumor":[56],"sites.":[57],"This":[58],"study":[59],"is":[60],"focused":[61],"on":[62,214],"modeling":[63],"the":[64,124,130,139,166,189,204,219,236],"profile":[66],"chitosan/zeolite":[69,90,144,167],"beads":[71,241],"system":[73],"encapsulating":[74,180],"The":[76,89,143,161,198],"nanocomposites":[77],"were":[78,186],"synthesized":[79],"by":[80],"functionalizing":[81],"zeolite":[82,237],"with":[83,223],"chitosan":[84,239],"subsequently":[86],"loading":[87,109],"was":[92,171],"characterized":[93],"its":[95],"physicochemical":[96],"properties,":[97],"including":[98],"surface":[99],"morphology,":[100],"functional":[101],"groups,":[102],"elemental":[103],"profile,":[104],"crystal":[105],"structure,":[106],"capacity":[110],"using":[111,188],"SEM,":[112],"FTIR,":[113],"EDS,":[114],"XRD,":[115],"UV\u2013vis":[117],"spectrophotometer":[118],"respectively.":[119],"In":[120],"vitro":[121],"experiments":[122],"investigated":[123],"kinetics":[126,185],"curcumin":[128],"from":[129,209],"composite":[131],"environments,":[135],"providing":[136],"insights":[137],"into":[138],"behavior.":[142],"demonstrated":[146],"controlled,":[148],"exhibiting":[154],"significant":[155],"optimizing":[158],"therapeutic":[159,258],"outcomes.":[160],"maximum":[162],"entrapment":[163],"efficiency":[164,178],"vehicle":[170],"recorded":[172],"at":[173],"84":[174],"%,":[175],"indicating":[176],"high":[177],"molecules.":[182],"Drug":[183],"analysed":[187],"Higuchi,":[190],"Korsmeyer":[191],"Peppas,":[192],"Zero-Order,":[193],"First-Order,":[194],"Hixson-Crowell":[196],"models.":[197],"Higuchi":[199],"kinetic":[200],"model,":[201],"which":[202],"explains":[203],"rate":[206],"drugs":[208],"insoluble":[211],"matrix":[212],"based":[213],"Fickian":[215],"diffusion,":[216],"best":[217],"explained":[218],"correlation":[225],"coefficient":[226],"R":[228],"2":[229],"=":[230],"0.9351.":[231],"These":[232],"results":[233],"indicate":[234],"that":[235],"functionalized":[238],"hold":[242],"promise":[243],"as":[244],"viable":[246],"platform":[247],"delivery,":[251],"enabling":[252],"prolonged":[253],"circulation":[255],"improved":[257],"outcome.":[259]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":6}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}
