{"id":"https://openalex.org/W4408804664","doi":"https://doi.org/10.1111/cpr.70026","title":"Exercise Delays Brain Ageing Through Muscle\u2010Brain Crosstalk","display_name":"Exercise Delays Brain Ageing Through Muscle\u2010Brain Crosstalk","publication_year":2025,"publication_date":"2025-03-24","ids":{"openalex":"https://openalex.org/W4408804664","doi":"https://doi.org/10.1111/cpr.70026","pmid":"https://pubmed.ncbi.nlm.nih.gov/40125692","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12240646"},"language":"en","primary_location":{"id":"doi:10.1111/cpr.70026","doi":"https://doi.org/10.1111/cpr.70026","is_oa":true,"landing_page_url":"https://doi.org/10.1111/cpr.70026","pdf_url":null,"source":{"id":"https://openalex.org/S86484535","display_name":"Cell Proliferation","issn_l":"0960-7722","issn":["0960-7722","1365-2184"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Proliferation","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1111/cpr.70026","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5021292666","display_name":"Shirin Pourteymour","orcid":"https://orcid.org/0000-0003-4538-3650","observed_orcids":["https://orcid.org/0000-0003-4538-3650"]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":true,"raw_author_name":"Shirin Pourteymour","raw_affiliation_strings":["Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway"],"raw_orcid":"https://orcid.org/0000-0003-4538-3650","affiliations":[{"raw_affiliation_string":"Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052044935","display_name":"Rakesh Kumar Majhi","orcid":"https://orcid.org/0000-0001-6999-1349","observed_orcids":["https://orcid.org/0000-0001-6999-1349"]},"institutions":[{"id":"https://openalex.org/I94234084","display_name":"Indian Institute of Technology Kanpur","ror":"https://ror.org/05pjsgx75","country_code":"IN","type":"education","lineage":["https://openalex.org/I94234084"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rakesh Kumar Majhi","raw_affiliation_strings":["Center of Excellence in Cancer, Gangwal School of Medical Science and Technology, Indian Institute of Technology Kanpur, Kanpur, India","Tissue Restoration Lab, Department of Biological Sciences and Bioengineering, Mehta Family Center for Engineering in Medicine, Indian Institute of Technology Kanpur, Kanpur, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Excellence in Cancer, Gangwal School of Medical Science and Technology, Indian Institute of Technology Kanpur, Kanpur, India","institution_ids":["https://openalex.org/I94234084"]},{"raw_affiliation_string":"Tissue Restoration Lab, Department of Biological Sciences and Bioengineering, Mehta Family Center for Engineering in Medicine, Indian Institute of Technology Kanpur, Kanpur, India","institution_ids":["https://openalex.org/I94234084"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030143970","display_name":"Frode Norheim","orcid":"https://orcid.org/0000-0002-5319-5679","observed_orcids":["https://orcid.org/0000-0002-5319-5679"]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Frode A. Norheim","raw_affiliation_strings":["Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072476830","display_name":"Christian Andre Drevon","orcid":"https://orcid.org/0000-0002-7216-2784","observed_orcids":["https://orcid.org/0000-0002-7216-2784"]},"institutions":[{"id":"https://openalex.org/I184942183","display_name":"University of Oslo","ror":"https://ror.org/01xtthb56","country_code":"NO","type":"education","lineage":["https://openalex.org/I184942183"]},{"id":"https://openalex.org/I4210118627","display_name":"Vitas (Norway)","ror":"https://ror.org/02ef5kc35","country_code":"NO","type":"company","lineage":["https://openalex.org/I4210118627"]}],"countries":["NO"],"is_corresponding":false,"raw_author_name":"Christian A. Drevon","raw_affiliation_strings":["Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway","Vitas Ltd, Oslo, Norway"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway","institution_ids":["https://openalex.org/I184942183"]},{"raw_affiliation_string":"Vitas Ltd, Oslo, Norway","institution_ids":["https://openalex.org/I4210118627"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5021292666"],"corresponding_institution_ids":["https://openalex.org/I184942183"],"apc_list":{"value":3680,"currency":"USD","value_usd":3680},"apc_paid":{"value":3680,"currency":"USD","value_usd":3680},"fwci":2.278,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.8965734,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"58","issue":"7","first_page":"e70026","last_page":"e70026"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.4372999966144562,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.4372999966144562,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.2953999936580658,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.10360000282526016,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exercise","display_name":"physical activity","score":0.9430000185966492},{"id":"https://openalex.org/keywords/brain-aging","display_name":"brain aging","score":0.9990000128746033},{"id":"https://openalex.org/keywords/myokines","display_name":"myokines","score":0.9890000224113464},{"id":"https://openalex.org/keywords/brain-derived-neurotrophic-factor","display_name":"brain-derived neurotrophic factor","score":0.9570000171661377},{"id":"https://openalex.org/keywords/macrophage-colony-stimulating-factor","display_name":"macrophage colony-stimulating factor","score":0.9829999804496765},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cathepsin-b","display_name":"cathepsin B","score":1.0},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.972000002861023},{"id":"https://openalex.org/keywords/dementia","display_name":"dementia","score":0.6930000185966492},{"id":"https://openalex.org/keywords/neurodegenerative-diseases","display_name":"neurodegenerative diseases","score":0.8619999885559082},{"id":"https://openalex.org/keywords/skeletal-muscle","display_name":"skeletal muscle","score":0.5580000281333923}],"concepts":[{"id":"https://openalex.org/C117365660","wikidata":"https://www.wikidata.org/wiki/Q962589","display_name":"Myokine","level":3,"score":0.6771306991577148},{"id":"https://openalex.org/C500499127","wikidata":"https://www.wikidata.org/wiki/Q332154","display_name":"Ageing","level":2,"score":0.6646697521209717},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6294316649436951},{"id":"https://openalex.org/C2984863031","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Cognitive decline","level":4,"score":0.6226388216018677},{"id":"https://openalex.org/C87753298","wikidata":"https://www.wikidata.org/wiki/Q17157137","display_name":"Neuroinflammation","level":3,"score":0.6108717918395996},{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.6027461290359497},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.5648032426834106},{"id":"https://openalex.org/C160539049","wikidata":"https://www.wikidata.org/wiki/Q3064187","display_name":"Neurotrophic factors","level":3,"score":0.5181280970573425},{"id":"https://openalex.org/C2778790584","wikidata":"https://www.wikidata.org/wiki/Q123045","display_name":"Brain-derived neurotrophic factor","level":4,"score":0.46485674381256104},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.45800185203552246},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.45511630177497864},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.4303535521030426},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38844403624534607},{"id":"https://openalex.org/C2779959927","wikidata":"https://www.wikidata.org/wiki/Q1048687","display_name":"Skeletal muscle","level":2,"score":0.2745369076728821},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.17991536855697632},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1592610776424408},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1111/cpr.70026","doi":"https://doi.org/10.1111/cpr.70026","is_oa":true,"landing_page_url":"https://doi.org/10.1111/cpr.70026","pdf_url":null,"source":{"id":"https://openalex.org/S86484535","display_name":"Cell Proliferation","issn_l":"0960-7722","issn":["0960-7722","1365-2184"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Proliferation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12240646","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12240646/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12240646/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Prolif","raw_type":"Text"},{"id":"pmid:40125692","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40125692","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell proliferation","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/cpr.70026","doi":"https://doi.org/10.1111/cpr.70026","is_oa":true,"landing_page_url":"https://doi.org/10.1111/cpr.70026","pdf_url":null,"source":{"id":"https://openalex.org/S86484535","display_name":"Cell Proliferation","issn_l":"0960-7722","issn":["0960-7722","1365-2184"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Proliferation","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4094554308","display_name":"SCIENTIA-FELLOWS II: International Postdoctoral Fellowship Programme","funder_award_id":"801133","funder_id":"https://openalex.org/F4320338337","funder_display_name":"H2020 Marie Sk\u0142odowska-Curie Actions"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320338337","display_name":"H2020 Marie Sk\u0142odowska-Curie Actions","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4408804664.pdf","grobid_xml":"https://content.openalex.org/works/W4408804664.grobid-xml"},"referenced_works_count":239,"referenced_works":["https://openalex.org/W31909416","https://openalex.org/W37344274","https://openalex.org/W122369139","https://openalex.org/W1503518593","https://openalex.org/W1566764955","https://openalex.org/W1586250986","https://openalex.org/W1595936241","https://openalex.org/W1754916819","https://openalex.org/W1762188861","https://openalex.org/W1766928376","https://openalex.org/W1770880387","https://openalex.org/W1859711096","https://openalex.org/W1881366512","https://openalex.org/W1938707617","https://openalex.org/W1959902108","https://openalex.org/W1967135649","https://openalex.org/W1968161190","https://openalex.org/W1968212163","https://openalex.org/W1968668396","https://openalex.org/W1969736263","https://openalex.org/W1969832325","https://openalex.org/W1971281741","https://openalex.org/W1972280500","https://openalex.org/W1974170967","https://openalex.org/W1976933297","https://openalex.org/W1978668014","https://openalex.org/W1979794821","https://openalex.org/W1979866949","https://openalex.org/W1981443842","https://openalex.org/W1982442539","https://openalex.org/W1984058396","https://openalex.org/W1991316205","https://openalex.org/W1991856249","https://openalex.org/W1993439506","https://openalex.org/W1994459030","https://openalex.org/W1995341268","https://openalex.org/W1998750669","https://openalex.org/W2001221313","https://openalex.org/W2003497613","https://openalex.org/W2006000330","https://openalex.org/W2007812767","https://openalex.org/W2007960303","https://openalex.org/W2009830651","https://openalex.org/W2012375413","https://openalex.org/W2012403948","https://openalex.org/W2012470325","https://openalex.org/W2013616388","https://openalex.org/W2013859768","https://openalex.org/W2014006342","https://openalex.org/W2019539642","https://openalex.org/W2020139159","https://openalex.org/W2021515441","https://openalex.org/W2021561499","https://openalex.org/W2023242764","https://openalex.org/W2024715836","https://openalex.org/W2024951071","https://openalex.org/W2025258306","https://openalex.org/W2026483971","https://openalex.org/W2029048316","https://openalex.org/W2032370338","https://openalex.org/W2033045687","https://openalex.org/W2034154112","https://openalex.org/W2034275438","https://openalex.org/W2038601986","https://openalex.org/W2041787131","https://openalex.org/W2047575176","https://openalex.org/W2047992751","https://openalex.org/W2048890665","https://openalex.org/W2049766993","https://openalex.org/W2053079324","https://openalex.org/W2063680739","https://openalex.org/W2064758288","https://openalex.org/W2065036402","https://openalex.org/W2065859331","https://openalex.org/W2069270259","https://openalex.org/W2071208440","https://openalex.org/W2071804866","https://openalex.org/W2072992430","https://openalex.org/W2074077703","https://openalex.org/W2074572113","https://openalex.org/W2075455339","https://openalex.org/W2076680453","https://openalex.org/W2078813265","https://openalex.org/W2078945917","https://openalex.org/W2082095985","https://openalex.org/W2083016464","https://openalex.org/W2083805707","https://openalex.org/W2085397620","https://openalex.org/W2094149847","https://openalex.org/W2094569055","https://openalex.org/W2095152560","https://openalex.org/W2095587767","https://openalex.org/W2095621691","https://openalex.org/W2101967150","https://openalex.org/W2102672973","https://openalex.org/W2103069600","https://openalex.org/W2103488083","https://openalex.org/W2103539671","https://openalex.org/W2107501599","https://openalex.org/W2108559479","https://openalex.org/W2110341145","https://openalex.org/W2111001697","https://openalex.org/W2111106822","https://openalex.org/W2111496468","https://openalex.org/W2112499304","https://openalex.org/W2114129845","https://openalex.org/W2115309238","https://openalex.org/W2116852067","https://openalex.org/W2117830068","https://openalex.org/W2118355993","https://openalex.org/W2118905653","https://openalex.org/W2121101037","https://openalex.org/W2122114464","https://openalex.org/W2127807410","https://openalex.org/W2129030266","https://openalex.org/W2130248772","https://openalex.org/W2130780675","https://openalex.org/W2135251891","https://openalex.org/W2135890213","https://openalex.org/W2142514276","https://openalex.org/W2143931350","https://openalex.org/W2145235967","https://openalex.org/W2145870733","https://openalex.org/W2147243367","https://openalex.org/W2151936757","https://openalex.org/W2157097177","https://openalex.org/W2157110881","https://openalex.org/W2160333751","https://openalex.org/W2160816909","https://openalex.org/W2161002325","https://openalex.org/W2161120457","https://openalex.org/W2166106170","https://openalex.org/W2169406722","https://openalex.org/W2172610621","https://openalex.org/W2183874293","https://openalex.org/W2231740780","https://openalex.org/W2262705777","https://openalex.org/W2275539726","https://openalex.org/W2411557189","https://openalex.org/W2415682939","https://openalex.org/W2470343227","https://openalex.org/W2492052693","https://openalex.org/W2504897690","https://openalex.org/W2535510210","https://openalex.org/W2580171604","https://openalex.org/W2591525585","https://openalex.org/W2599283944","https://openalex.org/W2608193295","https://openalex.org/W2609734061","https://openalex.org/W2618848734","https://openalex.org/W2619465759","https://openalex.org/W2622229215","https://openalex.org/W2623671090","https://openalex.org/W2624853583","https://openalex.org/W2652911668","https://openalex.org/W2734585321","https://openalex.org/W2749992340","https://openalex.org/W2750784726","https://openalex.org/W2766233891","https://openalex.org/W2766280419","https://openalex.org/W2769573610","https://openalex.org/W2773711501","https://openalex.org/W2774409221","https://openalex.org/W2781858988","https://openalex.org/W2790402451","https://openalex.org/W2791398439","https://openalex.org/W2792218150","https://openalex.org/W2792340030","https://openalex.org/W2801684035","https://openalex.org/W2804087978","https://openalex.org/W2884814715","https://openalex.org/W2886114630","https://openalex.org/W2890598563","https://openalex.org/W2898955021","https://openalex.org/W2910861117","https://openalex.org/W2918724159","https://openalex.org/W2918857132","https://openalex.org/W2920708784","https://openalex.org/W2947894976","https://openalex.org/W2950439492","https://openalex.org/W2958717882","https://openalex.org/W2965401191","https://openalex.org/W2971337283","https://openalex.org/W2972034054","https://openalex.org/W2981624110","https://openalex.org/W2981880738","https://openalex.org/W2991269179","https://openalex.org/W2998664097","https://openalex.org/W3002341835","https://openalex.org/W3004340994","https://openalex.org/W3012729670","https://openalex.org/W3013269049","https://openalex.org/W3034731041","https://openalex.org/W3039429797","https://openalex.org/W3041860193","https://openalex.org/W3086049294","https://openalex.org/W3092420818","https://openalex.org/W3094453298","https://openalex.org/W3107878680","https://openalex.org/W3117177327","https://openalex.org/W3124550675","https://openalex.org/W3127806509","https://openalex.org/W3133854972","https://openalex.org/W3160841217","https://openalex.org/W3161410779","https://openalex.org/W3183984755","https://openalex.org/W3184377705","https://openalex.org/W3188936098","https://openalex.org/W3198384913","https://openalex.org/W3199910466","https://openalex.org/W4200434404","https://openalex.org/W4205679789","https://openalex.org/W4205987369","https://openalex.org/W4210821588","https://openalex.org/W4213149191","https://openalex.org/W4220828826","https://openalex.org/W4241510428","https://openalex.org/W4282913696","https://openalex.org/W4282960775","https://openalex.org/W4282983570","https://openalex.org/W4288514362","https://openalex.org/W4308775127","https://openalex.org/W4309507742","https://openalex.org/W4309711138","https://openalex.org/W4318039791","https://openalex.org/W4323353266","https://openalex.org/W4323534192","https://openalex.org/W4360613811","https://openalex.org/W4384925390","https://openalex.org/W4385802570","https://openalex.org/W4386866314","https://openalex.org/W4386885207","https://openalex.org/W4388583270","https://openalex.org/W4390793814","https://openalex.org/W4391286717","https://openalex.org/W4392247371","https://openalex.org/W4401826249","https://openalex.org/W4402169022","https://openalex.org/W7028228764"],"related_works":["https://openalex.org/W6888886386","https://openalex.org/W7133551925","https://openalex.org/W7156200206","https://openalex.org/W7162532435","https://openalex.org/W2918857132","https://openalex.org/W4413139975","https://openalex.org/W4317927178","https://openalex.org/W4388978257","https://openalex.org/W3160803866","https://openalex.org/W4411224706"],"abstract_inverted_index":{"Ageing":[0],"is":[1,14,45],"often":[2],"accompanied":[3],"by":[4],"cognitive":[5,24,108],"decline":[6],"and":[7,22,33,41,61,96,105,113],"an":[8],"increased":[9,114],"risk":[10],"of":[11,127],"dementia.":[12],"Exercise":[13],"a":[15,137],"powerful":[16],"tool":[17],"for":[18],"slowing":[19],"brain":[20,43,62,71,81,104,142],"ageing":[21,44,103],"enhancing":[23],"function,":[25],"as":[26,28],"well":[27],"alleviating":[29],"depression,":[30],"improving":[31],"sleep,":[32],"promoting":[34],"overall":[35],"well-being.":[36],"The":[37],"connection":[38],"between":[39,59,79],"exercise":[40,60,128],"healthy":[42],"particularly":[46],"intriguing,":[47],"with":[48,82],"exercise-induced":[49],"pathways":[50],"playing":[51],"key":[52],"roles.":[53],"This":[54],"review":[55],"explores":[56],"the":[57,70,77,80,102,122,125,133,145],"link":[58],"health,":[63],"focusing":[64],"on":[65,124,129],"how":[66],"skeletal":[67],"muscle":[68],"influences":[69],"through":[72],"muscle-brain":[73],"crosstalk.":[74],"We":[75],"examine":[76,121],"interaction":[78],"well-known":[83],"myokines,":[84],"including":[85],"brain-derived":[86],"neurotrophic":[87],"factor,":[88,91],"macrophage":[89],"colony-stimulating":[90],"vascular":[92],"endothelial":[93],"growth":[94],"factor":[95,139],"cathepsin":[97],"B.":[98],"Neuroinflammation":[99],"accumulates":[100],"in":[101,132,140],"leads":[106],"to":[107,116],"decline,":[109],"impaired":[110],"motor":[111],"skills":[112],"susceptibility":[115],"neurodegenerative":[117],"diseases.":[118],"Finally,":[119],"we":[120],"evidence":[123],"effects":[126],"neuronal":[130],"myelination":[131],"central":[134],"nervous":[135],"system,":[136],"crucial":[138],"maintaining":[141],"health":[143],"throughout":[144],"lifespan.":[146]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":5}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2025-03-25T00:00:00"}