{"id":"https://openalex.org/W4408731069","doi":"https://doi.org/10.32000/2072-1757-2025-1-21-26","title":"Acute lymphoblastic leukemia in children","display_name":"Acute lymphoblastic leukemia in children","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4408731069","doi":"https://doi.org/10.32000/2072-1757-2025-1-21-26"},"language":"en","primary_location":{"id":"doi:10.32000/2072-1757-2025-1-21-26","doi":"https://doi.org/10.32000/2072-1757-2025-1-21-26","is_oa":false,"landing_page_url":"https://doi.org/10.32000/2072-1757-2025-1-21-26","pdf_url":null,"source":{"id":"https://openalex.org/S4210177312","display_name":"Practical medicine","issn_l":"2072-1757","issn":["2072-1757","2307-3217"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Practical medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108810402","display_name":"A. V. Dubovaya","orcid":"https://orcid.org/0000-0002-7999-8656","observed_orcids":["https://orcid.org/0000-0002-7999-8656"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. V. DUBOVAYA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040799938","display_name":"\u041d\u0430\u0434\u0435\u0436\u0434\u0430 \u0410\u043b\u0435\u043a\u0441\u0435\u0435\u0432\u043d\u0430 \u0423\u0441\u0435\u043d\u043a\u043e","orcid":"https://orcid.org/0000-0001-6729-3248","observed_orcids":["https://orcid.org/0000-0001-6729-3248"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. A. USENKO","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011896839","display_name":"S.A. Yuldasheva","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. A. YULDASHEVA","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5116747396","display_name":"N. V. BURYAK","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"N. V. BURYAK","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2455,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.7567109,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"23","issue":"1","first_page":"21","last_page":"26"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acute-lymphoblastic-leukemia","display_name":"acute lymphoblastic leukemia","score":0.996999979019165},{"id":"https://openalex.org/keywords/pediatric-leukemia","display_name":"pediatric leukemia","score":0.8299999833106995},{"id":"https://openalex.org/keywords/chemotherapy-protocols","display_name":"chemotherapy protocols","score":0.8579999804496765},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.7570000290870667},{"id":"https://openalex.org/keywords/molecular-genetic-characteristics","display_name":"molecular genetic characteristics","score":0.7229999899864197},{"id":"https://openalex.org/keywords/immunophenotype","display_name":"immunophenotype","score":0.8569999933242798},{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.6420000195503235},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.9369999766349792},{"id":"https://openalex.org/keywords/5-year-survival","display_name":"five-year survival","score":0.7519999742507935},{"id":"https://openalex.org/keywords/pathogenesis","display_name":"pathogenesis","score":0.7919999957084656}],"concepts":[{"id":"https://openalex.org/C2909962599","wikidata":"https://www.wikidata.org/wiki/Q180664","display_name":"Lymphoblastic Leukemia","level":3,"score":0.7473201751708984},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6174058318138123},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.3705318570137024},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25748512148857117}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.32000/2072-1757-2025-1-21-26","doi":"https://doi.org/10.32000/2072-1757-2025-1-21-26","is_oa":false,"landing_page_url":"https://doi.org/10.32000/2072-1757-2025-1-21-26","pdf_url":null,"source":{"id":"https://openalex.org/S4210177312","display_name":"Practical medicine","issn_l":"2072-1757","issn":["2072-1757","2307-3217"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["russia-white-list-3"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Practical medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2148544170","https://openalex.org/W2053265271","https://openalex.org/W1979320164","https://openalex.org/W7100189909","https://openalex.org/W2548709641","https://openalex.org/W3113451244","https://openalex.org/W1988227432","https://openalex.org/W4249547460","https://openalex.org/W5941866","https://openalex.org/W4322389939"],"abstract_inverted_index":{"Studying":[0],"approaches":[1,159],"to":[2,52,72,156,160],"the":[3,19,23,31,39,68,95,113,122,131,139,149,161,171],"treatment":[4,81,96,126,162],"of":[5,34,45,58,62,90,97,115,124,133,143,148,163],"acute":[6,98,164],"lymphoblastic":[7,99,165],"leukemia":[8,100,166],"(ALL)":[9],"in":[10,22,80,101,167],"children":[11,168],"is":[12,18],"relevant":[13],"because":[14],"this":[15],"oncohematological":[16],"pathology":[17],"most":[20,172],"common":[21],"pediatric":[24,63],"population.":[25],"Modern":[26],"chemotherapy":[27],"protocols":[28],"provide":[29],"for":[30,175],"differentiated":[32],"use":[33],"cytostatics,":[35],"taking":[36,128],"into":[37,129],"account":[38,130],"immunophenotypic":[40],"and":[41,76,109,138,169],"molecular":[42,140],"genetic":[43,141],"characteristics":[44,142],"tumor":[46,144],"cells.":[47,145],"This":[48],"makes":[49],"it":[50,154],"possible":[51,155],"achieve":[53],"a":[54,87],"five-year":[55],"survival":[56],"rate":[57],"more":[59],"than":[60],"90%":[61],"patients":[64,134],"with":[65],"ALL.":[66],"However,":[67],"ALL":[69],"forms":[70],"resistant":[71],"chemotherapy,":[73],"high-risk":[74],"patients,":[75],"relapses":[77],"force":[78],"improvements":[79],"methods.":[82],"The":[83,146],"above":[84],"circumstances":[85],"necessitate":[86],"comprehensive":[88],"analysis":[89],"modern":[91,158],"scientific":[92],"data":[93,105],"on":[94,106,112],"children,":[102],"systematize":[103,157],"current":[104],"pathogenetic":[107],"mechanisms":[108],"their":[110],"impact":[111],"choice":[114],"therapeutic":[116],"tactics,":[117],"as":[118,120],"well":[119],"analyze":[121],"effectiveness":[123],"existing":[125],"protocols,":[127],"stratification":[132],"by":[135],"risk":[136],"groups":[137],"implementation":[147],"tasks":[150],"set":[151],"will":[152],"make":[153],"identify":[170],"promising":[173],"areas":[174],"further":[176],"research.":[177]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2025-03-22T00:00:00"}