{"id":"https://openalex.org/W4408553153","doi":"https://doi.org/10.58837/chula.the.2007.1000","title":"Synthesis of epicatechin glycosides via specific transglycosylation of cyclodextrin glycosyltransferase","display_name":"Synthesis of epicatechin glycosides via specific transglycosylation of cyclodextrin glycosyltransferase","publication_year":2007,"publication_date":"2007-01-01","ids":{"openalex":"https://openalex.org/W4408553153","doi":"https://doi.org/10.58837/chula.the.2007.1000"},"language":"en","primary_location":{"id":"doi:10.58837/chula.the.2007.1000","doi":"https://doi.org/10.58837/chula.the.2007.1000","is_oa":false,"landing_page_url":"https://doi.org/10.58837/chula.the.2007.1000","pdf_url":null,"source":{"id":"https://openalex.org/S7407060144","display_name":"Chula Digiverse","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chulalongkorn University","raw_type":"dissertation"},"parent_works":[],"lineage":["https://openalex.org/W4408553153"],"child_works_count":0,"type":"dissertation","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067840793","display_name":"Pornpun Aramsangtienchai","orcid":"https://orcid.org/0000-0002-9079-5446","observed_orcids":["https://orcid.org/0000-0002-9079-5446"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Pornpun Aramsangtienchai","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Piamsook Pongsawasdi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Piamsook Pongsawasdi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5073908772","display_name":"Warinthorn Chavasiri","orcid":"https://orcid.org/0000-0001-5201-1324","observed_orcids":["https://orcid.org/0000-0001-5201-1324"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Warinthorn Chavasiri","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5067840793"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.37400001287460327,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.37400001287460327,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis","score":0.295199990272522,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.2786000072956085,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transglycosylation","display_name":"transglycosylation","score":0.9010000228881836},{"id":"https://openalex.org/keywords/cyclodextrin-glycosyltransferase","display_name":"cyclodextrin glycosyltransferase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/epigallocatechin-gallate","display_name":"epigallocatechin gallate","score":0.8619999885559082},{"id":"https://openalex.org/keywords/epicatechin","display_name":"epicatechin","score":0.7429999709129333},{"id":"https://openalex.org/keywords/beta-cyclodextrin","display_name":"\u03b2-cyclodextrin","score":0.9110000133514404},{"id":"https://openalex.org/keywords/epimerization","display_name":"epimerization","score":0.8989999890327454},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.6370000243186951},{"id":"https://openalex.org/keywords/catechins","display_name":"catechins","score":0.621999979019165}],"concepts":[{"id":"https://openalex.org/C2779433975","wikidata":"https://www.wikidata.org/wiki/Q40417805","display_name":"Cyclodextrin","level":2,"score":0.7408895492553711},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.6603941917419434},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5637321472167969},{"id":"https://openalex.org/C161019410","wikidata":"https://www.wikidata.org/wiki/Q67201373","display_name":"Glycosyltransferase","level":3,"score":0.42294588685035706},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.3089229464530945},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2512884736061096},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.09704303741455078}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.58837/chula.the.2007.1000","doi":"https://doi.org/10.58837/chula.the.2007.1000","is_oa":false,"landing_page_url":"https://doi.org/10.58837/chula.the.2007.1000","pdf_url":null,"source":{"id":"https://openalex.org/S7407060144","display_name":"Chula Digiverse","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chulalongkorn University","raw_type":"dissertation"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2085196113","https://openalex.org/W2810848190","https://openalex.org/W2791647217","https://openalex.org/W2043441588","https://openalex.org/W2073748340","https://openalex.org/W4376631131","https://openalex.org/W7199702919","https://openalex.org/W4408555399","https://openalex.org/W4408556226","https://openalex.org/W1969730691"],"abstract_inverted_index":{"Transglycosylation":[0],"of":[1,85,112,120,140,144,181,191,217,240,253,274,281],"catechins":[2],"by":[3,21,71,198,259,278],"partially":[4],"purified":[5],"cyclodextrin":[6],"glycosyltransferase":[7],"(CGTase)":[8],"from":[9],"Paenibacillus":[10],"sp.RB01":[11],"was":[12,60,116,148,187,243,256,264,276],"investigated.":[13],"Three":[14],"to":[15,146,237],"four":[16],"glucoside":[17,195],"products":[18,65,160,196,255],"were":[19,69,131,161,168,203,226,288],"obtained":[20],"TLC":[22],"analysis":[23],"when":[24],"used":[25],"(+)":[26],"catechin,":[27],"(-)":[28,31],"epicatechin,":[29,218,282],"or":[30],"epigallocatechin":[32,48],"gallate":[33,49],"as":[34,38,80],"acceptor":[35,45,82],"and":[36,93,128,135,155,167,173,200,209,221,229,248,285,291],"beta-cyclodextrin":[37],"glucosyl":[39],"donor.":[40],"The":[41,109,118,178,189,214,250],"enzyme":[42],"showed":[43],"higher":[44,244],"specificity":[46,53],"towards":[47],"whereas":[50],"the":[51,63,67,73,192,219,222,234,254,267,272,283,286],"same":[52],"for":[54,76,106],"donor":[55],"substrate":[56],"(starch,":[57],"beta-cyclodextrin,":[58],"maltoheptaose)":[59],"demonstrated.":[61],"When":[62],"occurred":[64],"in":[66,97,164,224],"reaction":[68],"analyzed":[70],"HPLC,":[72],"optimum":[74],"condition":[75],"transglucosylation":[77,141],"with":[78,89],"epicatechin":[79,96,145,241,246],"an":[81],"was:":[83],"incubation":[84,157],"80":[86],"U/ml":[87],"CGTase":[88],"1.0%":[90],"(w/v)":[91,95],"beta-CD":[92],"0.5%":[94],"10":[98],"mM":[99],"acetate":[100],"buffer,":[101],"pH":[102],"6.0":[103],"at":[104,123,150,184,270],"50\u2103":[105],"24":[107],"hours.":[108],"18.07":[110],"%":[111],"overall":[113],"product":[114,122,183],"yield":[115,180],"obtained.":[117,188],"amounts":[119],"each":[121],"Rt":[124],"27,":[125],"30,":[126],"45,":[127],"48":[129],"minutes":[130],"1.44%,":[132],"3.39%,":[133],"4.18%,":[134],"8.33%,":[136],"respectively.":[137,232,294],"During":[138],"optimization":[139],"reaction,":[142],"epimerization":[143],"catechin":[147],"observed":[149],"alkaline":[151],"pH,":[152],"high":[153],"temperature":[154],"longer":[156],"time.":[158],"Reaction":[159],"then":[162],"prepared":[163],"larger":[165],"scale":[166],"isolated":[169],"using":[170],"Sephadex":[171],"LH-20":[172],"C18-reversed":[174],"phase":[175],"HPLC":[176],"column.":[177],"5.6%":[179],"major":[182,194],"Rt48":[185,207],"min":[186],"structures":[190],"two":[193],"elucidated":[197],"MS":[199],"NMR":[201],"techniques":[202],"epicatechin-3\u0301":[204],"-O-\u03b1-D-glucopyranoside":[205],"(for":[206,211],"min)":[208],"epicatechin-3\u0301-O-\u03b1-D-diglucopyranoside":[210],"Rt45":[212],"min).":[213],"water":[215,225],"solubility":[216],"monoglucoside":[220,242,284],"diglucoside":[223,247,287],"4.9,":[227],"95":[228],"2.0":[230],"mg/ml,":[231],"While":[233],"browning":[235],"resistance":[236],"UV":[238],"irradiation":[239],"than":[245],"epicatechin.":[249],"antioxidant":[251],"activity":[252],"also":[257],"determined":[258],"DPPH":[260,275],"scavenging":[261],"assay.":[262],"It":[263],"found":[265],"that":[266],"inhibitory":[268],"concentrations":[269],"which":[271],"absorbance":[273],"reduced":[277],"50%":[279],"(IC\u2085\u2080)":[280],"25,":[289],"36":[290],"46":[292],"\u00b5M,":[293]},"counts_by_year":[],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2025-03-19T00:00:00"}