{"id":"https://openalex.org/W4408519614","doi":"https://doi.org/10.1109/jsen.2025.3550133","title":"Point-of-Care Optical Device for Estimation of \u03b1-Amylase Using Carbon Quantum Dots","display_name":"Point-of-Care Optical Device for Estimation of \u03b1-Amylase Using Carbon Quantum Dots","publication_year":2025,"publication_date":"2025-03-17","ids":{"openalex":"https://openalex.org/W4408519614","doi":"https://doi.org/10.1109/jsen.2025.3550133"},"language":"en","primary_location":{"id":"doi:10.1109/jsen.2025.3550133","doi":"https://doi.org/10.1109/jsen.2025.3550133","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jsen.2025.3550133","pdf_url":null,"source":{"id":"https://openalex.org/S189694085","display_name":"IEEE Sensors Journal","issn_l":"1530-437X","issn":["1530-437X","1558-1748","2379-9153"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-2","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321027","host_organization_name":"IEEE Sensors Council","host_organization_lineage":["https://openalex.org/P4310321027","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Sensors Council","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Sensors Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045786271","display_name":"Bethuel Daurai","orcid":"https://orcid.org/0000-0001-9794-7919","observed_orcids":["https://orcid.org/0000-0001-9794-7919"]},"institutions":[{"id":"https://openalex.org/I197465736","display_name":"North Eastern Hill University","ror":"https://ror.org/055m2tx54","country_code":"IN","type":"education","lineage":["https://openalex.org/I197465736"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bethuel Daurai","raw_affiliation_strings":["Department of Biomedical Engineering, North-Eastern Hill University, Shillong, India","Department of Biomedical Engineering, North-Eastern Hill University, Shillong, Meghalaya, India"],"raw_orcid":"https://orcid.org/0000-0001-9794-7919","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, North-Eastern Hill University, Shillong, India","institution_ids":["https://openalex.org/I197465736"]},{"raw_affiliation_string":"Department of Biomedical Engineering, North-Eastern Hill University, Shillong, Meghalaya, India","institution_ids":["https://openalex.org/I197465736"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087947360","display_name":"Arup Jyoti Baruah","orcid":"https://orcid.org/0000-0001-8041-5334","observed_orcids":["https://orcid.org/0000-0001-8041-5334"]},"institutions":[{"id":"https://openalex.org/I231543472","display_name":"North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences","ror":"https://ror.org/05gm3yv92","country_code":"IN","type":"education","lineage":["https://openalex.org/I231543472","https://openalex.org/I2799351866","https://openalex.org/I4210148677"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Arup Jyoti Baruah","raw_affiliation_strings":["Department of General Surgery, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong, Meghalaya, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences (NEIGRIHMS), Shillong, Meghalaya, India","institution_ids":["https://openalex.org/I231543472"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091084463","display_name":"Manashjit Gogoi","orcid":"https://orcid.org/0000-0002-1753-192X","observed_orcids":["https://orcid.org/0000-0002-1753-192X"]},"institutions":[{"id":"https://openalex.org/I197465736","display_name":"North Eastern Hill University","ror":"https://ror.org/055m2tx54","country_code":"IN","type":"education","lineage":["https://openalex.org/I197465736"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manashjit Gogoi","raw_affiliation_strings":["Department of Biomedical Engineering, North-Eastern Hill University, Shillong, India","Department of Biomedical Engineering, North-Eastern Hill University, Shillong, Meghalaya, India"],"raw_orcid":"https://orcid.org/0000-0002-1753-192X","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, North-Eastern Hill University, Shillong, India","institution_ids":["https://openalex.org/I197465736"]},{"raw_affiliation_string":"Department of Biomedical Engineering, North-Eastern Hill University, Shillong, Meghalaya, India","institution_ids":["https://openalex.org/I197465736"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":2645,"currency":"USD","value_usd":2645},"apc_paid":null,"fwci":0.4144,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.46272513,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"25","issue":"9","first_page":"16061","last_page":"16067"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11342","display_name":"Carbon and Quantum Dots Applications","score":0.8579000234603882,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11342","display_name":"Carbon and Quantum Dots Applications","score":0.8579000234603882,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.10570000112056732,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.014299999922513962,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alpha-amylase","display_name":"alpha-amylase","score":0.9330000281333923},{"id":"https://openalex.org/keywords/pancreatitis","display_name":"pancreatitis","score":0.7160000205039978},{"id":"https://openalex.org/keywords/point-of-care-devices","display_name":"point-of-care devices","score":0.7450000047683716},{"id":"https://openalex.org/keywords/carbon-quantum-dots","display_name":"carbon quantum dots","score":0.9990000128746033},{"id":"https://openalex.org/keywords/fluorescent-probes","display_name":"fluorescent probes","score":0.7149999737739563},{"id":"https://openalex.org/keywords/light-dependent-resistor","display_name":"light dependent resistor","score":0.753000020980835},{"id":"https://openalex.org/keywords/light-emitting-diodes","display_name":"light-emitting diodes","score":0.925000011920929},{"id":"https://openalex.org/keywords/citric-acid-pyrolysis","display_name":"citric acid pyrolysis","score":0.8799999952316284},{"id":"https://openalex.org/keywords/enzyme-activity-assay","display_name":"enzyme activity assay","score":0.6679999828338623}],"concepts":[{"id":"https://openalex.org/C124657808","wikidata":"https://www.wikidata.org/wiki/Q1133068","display_name":"Quantum dot","level":2,"score":0.7627164125442505},{"id":"https://openalex.org/C28719098","wikidata":"https://www.wikidata.org/wiki/Q44946","display_name":"Point (geometry)","level":2,"score":0.5500041246414185},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.4877980053424835},{"id":"https://openalex.org/C140205800","wikidata":"https://www.wikidata.org/wiki/Q5860","display_name":"Carbon fibers","level":3,"score":0.42290911078453064},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.403953492641449},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.3386358618736267},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33365970849990845},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1340087354183197},{"id":"https://openalex.org/C104779481","wikidata":"https://www.wikidata.org/wiki/Q50707","display_name":"Composite number","level":2,"score":0.09185859560966492},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.08561933040618896},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/jsen.2025.3550133","doi":"https://doi.org/10.1109/jsen.2025.3550133","is_oa":false,"landing_page_url":"https://doi.org/10.1109/jsen.2025.3550133","pdf_url":null,"source":{"id":"https://openalex.org/S189694085","display_name":"IEEE Sensors Journal","issn_l":"1530-437X","issn":["1530-437X","1558-1748","2379-9153"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-2","norway-2","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310321027","host_organization_name":"IEEE Sensors Council","host_organization_lineage":["https://openalex.org/P4310321027","https://openalex.org/P4310319808"],"host_organization_lineage_names":["IEEE Sensors Council","Institute of Electrical and Electronics Engineers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"IEEE Sensors Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7246000170707703}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W1499613462","https://openalex.org/W1996601343","https://openalex.org/W2005324630","https://openalex.org/W2044999311","https://openalex.org/W2111129827","https://openalex.org/W2167712978","https://openalex.org/W2175428308","https://openalex.org/W2337635689","https://openalex.org/W2761274930","https://openalex.org/W2903287413","https://openalex.org/W2914517170","https://openalex.org/W2916515437","https://openalex.org/W2917227477","https://openalex.org/W2972159574","https://openalex.org/W2994449347","https://openalex.org/W3004495212","https://openalex.org/W3034432597","https://openalex.org/W3086386450","https://openalex.org/W3096237149","https://openalex.org/W3112376372","https://openalex.org/W3120202688","https://openalex.org/W3131843789","https://openalex.org/W3134669425","https://openalex.org/W3139344314","https://openalex.org/W3167499894","https://openalex.org/W3184809847","https://openalex.org/W3196085321","https://openalex.org/W3215658811","https://openalex.org/W4205501273","https://openalex.org/W4210825058","https://openalex.org/W4211046208","https://openalex.org/W4212980780","https://openalex.org/W4214851146","https://openalex.org/W4224283187","https://openalex.org/W4294958489","https://openalex.org/W4313344105","https://openalex.org/W4365396084","https://openalex.org/W4383032978","https://openalex.org/W4386471087","https://openalex.org/W4391106818","https://openalex.org/W4391120201","https://openalex.org/W4400282868","https://openalex.org/W4402673281","https://openalex.org/W7071248520"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2935759653","https://openalex.org/W3105167352","https://openalex.org/W54078636","https://openalex.org/W2954470139","https://openalex.org/W1501425562","https://openalex.org/W2902782467","https://openalex.org/W3084825885","https://openalex.org/W2298861036","https://openalex.org/W2271181815"],"abstract_inverted_index":{"Alpha-amylase":[0],"($\\alpha":[1],"$-amylase)":[2],"is":[3,22,32],"an":[4,45],"enzyme":[5,151],"released":[6],"by":[7,24,55,73,142,147],"the":[8,20,35,42,51,75,98,112,143,148,176],"pancreas,":[9],"and":[10,62,83,162],"it":[11],"converts":[12],"starch":[13,92],"into":[14],"sugar.":[15],"Pancreatitis":[16],"or":[17],"inflammation":[18],"of":[19,34,44,53,91,126,159,175],"pancreas":[21],"detected":[23],"elevated":[25],"levels":[26],"of$\\alpha":[27],"$-amylase":[28,108,124],"in":[29],"blood.":[30],"It":[31],"one":[33],"biomarkers":[36],"for":[37,50,80,136,165],"pancreatitis.":[38],"This":[39,169],"study":[40,116],"investigated":[41],"development":[43],"optical":[46],"point-of-care":[47],"(POC)":[48],"device":[49,154,177],"detection":[52],"pancreatitis":[54],"estimating$\\alpha":[56],"$-amylase,":[57],"using":[58,97,182],"a":[59,63,103,157,171,185],"light-emitting":[60],"diode":[61],"light-dependent":[64],"resistor":[65],"(LDR).":[66],"We":[67,101],"synthesized":[68],"carbon":[69],"quantum":[70,104],"dots":[71],"(CDs)":[72],"pyrolyzing":[74],"citric":[76],"acid":[77],"at$200~^{\\circ":[78],"}$C":[79],"16":[81],"min":[82],"subsequently":[84],"conjugated":[85],"CDs":[86],"with":[87,122,150],"starch.":[88],"The":[89,115,129,153],"conjugation":[90],"to":[93,111,178],"CD":[94,183],"was":[95,109,140],"conducted":[96],"EDC-NHS":[99],"protocol.":[100],"observed":[102],"quenching":[105],"effect":[106],"when$\\alpha":[107],"added":[110],"starch-conjugated":[113],"CD.":[114],"utilized":[117],"artificial":[118],"blood":[119],"serum":[120],"(ABS)":[121],"an$\\alpha":[123],"range":[125],"42\u2013420":[127],"U/L.":[128],"CDs\u2019":[130],"potential":[131,172],"as":[132,184],"sensitive":[133],"fluorescent":[134,186],"probes":[135],"detecting":[137],"enzymatic":[138],"activity":[139],"indicated":[141],"negative":[144],"correlation":[145],"disclosed":[146],"measurements":[149],"concentration.":[152],"developed":[155],"obtained":[156],"sensitivity":[158],"0.079":[160],"a.u.L/U":[161],"an${R}^{{2}}$of":[163],"0.99":[164],"its":[166],"calibration":[167],"curve.":[168],"illustrates":[170],"POC":[173],"implementation":[174],"identify":[179],"acute":[180],"pancreatitis,":[181],"probe.":[187]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-03-18T00:00:00"}