{"id":"https://openalex.org/W4408301034","doi":"https://doi.org/10.1002/jbm.a.37893","title":"Cell\u2010Derived Basal Membrane\u2010Like Extracellular Matrix Promotes Endothelial Cell Expansion and Functionalization","display_name":"Cell\u2010Derived Basal Membrane\u2010Like Extracellular Matrix Promotes Endothelial Cell Expansion and Functionalization","publication_year":2025,"publication_date":"2025-03-01","ids":{"openalex":"https://openalex.org/W4408301034","doi":"https://doi.org/10.1002/jbm.a.37893","pmid":"https://pubmed.ncbi.nlm.nih.gov/40059713"},"language":"en","primary_location":{"id":"doi:10.1002/jbm.a.37893","doi":"https://doi.org/10.1002/jbm.a.37893","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jbm.a.37893","pdf_url":null,"source":{"id":"https://openalex.org/S184573928","display_name":"Journal of Biomedical Materials Research Part A","issn_l":"1549-3296","issn":["1549-3296","1552-4965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research Part A","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102841515","display_name":"Jiangwei Xiao","orcid":"https://orcid.org/0000-0002-5384-7489","observed_orcids":["https://orcid.org/0000-0002-5384-7489"]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jiangwei Xiao","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":"https://orcid.org/0000-0002-5384-7489","affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kai You","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai You","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061473473","display_name":"Daohuan Lu","orcid":"https://orcid.org/0000-0002-4517-5416","observed_orcids":["https://orcid.org/0000-0002-4517-5416"]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Daohuan Lu","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010238645","display_name":"Shuwen Guan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shuwen Guan","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109883713","display_name":"Hengpeng Wu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hengpeng Wu","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083091848","display_name":"Jing Gao","orcid":"https://orcid.org/0000-0003-0357-570X","observed_orcids":["https://orcid.org/0000-0003-0357-570X"]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Gao","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091413959","display_name":"Yadong Tang","orcid":"https://orcid.org/0000-0001-6652-1640","observed_orcids":["https://orcid.org/0000-0001-6652-1640","https://orcid.org/0000-0003-0739-3815"]},"institutions":[{"id":"https://openalex.org/I139024713","display_name":"Guangdong University of Technology","ror":"https://ror.org/04azbjn80","country_code":"CN","type":"education","lineage":["https://openalex.org/I139024713"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yadong Tang","raw_affiliation_strings":["School of Biomedical and Pharmaceutical Sciences Guangdong University of Technology  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biomedical and Pharmaceutical Sciences Guangdong University of Technology  Guangzhou China","institution_ids":["https://openalex.org/I139024713"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072552462","display_name":"Shan Ping Yu","orcid":"https://orcid.org/0000-0003-2835-1040","observed_orcids":["https://orcid.org/0000-0003-2835-1040"]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shan Yu","raw_affiliation_strings":["Chemical Engineering Department Ningbo Key Laboratory of High Performance Petroleum Resin Preparation Engineering and Technology  Ningbo China","Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chemical Engineering Department Ningbo Key Laboratory of High Performance Petroleum Resin Preparation Engineering and Technology  Ningbo China","institution_ids":[]},{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]},{"author_position":"last","author":{"id":null,"display_name":"Botao Gao","orcid":"https://orcid.org/0000-0002-4411-0258","observed_orcids":["https://orcid.org/0000-0002-4411-0258"]},"institutions":[{"id":"https://openalex.org/I4210103524","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210103524"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Botao Gao","raw_affiliation_strings":["Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China"],"raw_orcid":"https://orcid.org/0000-0002-4411-0258","affiliations":[{"raw_affiliation_string":"Guangdong Provincial Key Laboratory of Medical Electronic Instruments and Materials Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]},{"raw_affiliation_string":"National Engineering Research Center for Healthcare Devices, Institute of Biological and Medical Engineering, Guangdong Academy of Sciences  Guangzhou China","institution_ids":["https://openalex.org/I4210103524"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5102841515"],"corresponding_institution_ids":["https://openalex.org/I4210103524"],"apc_list":{"value":4220,"currency":"USD","value_usd":4220},"apc_paid":null,"fwci":3.4741,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.91713,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"113","issue":"3","first_page":"e37893","last_page":"e37893"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cell-derived-extracellular-matrix","display_name":"cell-derived extracellular matrix","score":0.9010000228881836},{"id":"https://openalex.org/keywords/decellularized-extracellular-matrix","display_name":"decellularized extracellular matrix","score":0.7929999828338623},{"id":"https://openalex.org/keywords/basement-membrane-mimicry","display_name":"basement membrane mimicry","score":0.8500000238418579},{"id":"https://openalex.org/keywords/endothelial-function","display_name":"endothelial function","score":0.9039999842643738},{"id":"https://openalex.org/keywords/vascular-tissue-engineering","display_name":"vascular tissue engineering","score":0.8330000042915344},{"id":"https://openalex.org/keywords/biomimetic-scaffolds","display_name":"biomimetic scaffolds","score":0.7139999866485596},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.9039999842643738},{"id":"https://openalex.org/keywords/prostacyclin","display_name":"prostacyclin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/thrombomodulin","display_name":"thrombomodulin","score":0.9300000071525574},{"id":"https://openalex.org/keywords/tissue-factor-pathway-inhibitor","display_name":"tissue factor pathway inhibitor","score":0.9900000095367432},{"id":"https://openalex.org/keywords/vascular-endothelial-growth-factor","display_name":"vascular endothelial growth factor","score":0.8429999947547913},{"id":"https://openalex.org/keywords/endoglin","display_name":"CD105","score":0.9779999852180481},{"id":"https://openalex.org/keywords/cell-adhesion-and-migration","display_name":"cell adhesion and migration","score":0.7440000176429749}],"concepts":[{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7421061992645264},{"id":"https://openalex.org/C189165786","wikidata":"https://www.wikidata.org/wiki/Q193825","display_name":"Extracellular matrix","level":2,"score":0.7125782370567322},{"id":"https://openalex.org/C123012128","wikidata":"https://www.wikidata.org/wiki/Q5376430","display_name":"Endothelial stem cell","level":3,"score":0.659365713596344},{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.5625649690628052},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.49291515350341797},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4749743342399597},{"id":"https://openalex.org/C85789140","wikidata":"https://www.wikidata.org/wiki/Q187640","display_name":"Cell adhesion","level":3,"score":0.4441129267215729},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.33965563774108887},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2767556309700012},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.18691211938858032},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.1839480996131897},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1694890558719635},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11888283491134644}],"mesh":[{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000091083","descriptor_name":"Decellularized Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001485","descriptor_name":"Basement Membrane","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002465","descriptor_name":"Cell Movement","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005109","descriptor_name":"Extracellular Matrix","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008074","descriptor_name":"Lipoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009569","descriptor_name":"Nitric Oxide","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018180","descriptor_name":"Thrombomodulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018180","descriptor_name":"Thrombomodulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018180","descriptor_name":"Thrombomodulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D040761","descriptor_name":"Biomimetic Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D042783","descriptor_name":"Endothelial Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D054457","descriptor_name":"Tissue Scaffolds","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D061307","descriptor_name":"Human Umbilical Vein Endothelial Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1002/jbm.a.37893","doi":"https://doi.org/10.1002/jbm.a.37893","is_oa":false,"landing_page_url":"https://doi.org/10.1002/jbm.a.37893","pdf_url":null,"source":{"id":"https://openalex.org/S184573928","display_name":"Journal of Biomedical Materials Research Part A","issn_l":"1549-3296","issn":["1549-3296","1552-4965"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Biomedical Materials Research Part A","raw_type":"journal-article"},{"id":"pmid:40059713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40059713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of biomedical materials research. Part A","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1100568757","display_name":null,"funder_award_id":"2021GDASYL\u201020210102004","funder_id":"https://openalex.org/F4320335357","funder_display_name":"Guangdong Academy of Sciences"},{"id":"https://openalex.org/G162330680","display_name":null,"funder_award_id":"2022GDASZH\u20102022020402\u201001","funder_id":"https://openalex.org/F4320335357","funder_display_name":"Guangdong Academy of Sciences"},{"id":"https://openalex.org/G97998121","display_name":null,"funder_award_id":"2020GDASYL\u201020200102005","funder_id":"https://openalex.org/F4320335357","funder_display_name":"Guangdong Academy of Sciences"}],"funders":[{"id":"https://openalex.org/F4320335357","display_name":"Guangdong Academy of Sciences","ror":"https://ror.org/01g9hkj35"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":52,"referenced_works":["https://openalex.org/W751788624","https://openalex.org/W1854590830","https://openalex.org/W1893534297","https://openalex.org/W1958514349","https://openalex.org/W1985835454","https://openalex.org/W1989934900","https://openalex.org/W1992112833","https://openalex.org/W2013261475","https://openalex.org/W2035794631","https://openalex.org/W2036034164","https://openalex.org/W2047999162","https://openalex.org/W2049774540","https://openalex.org/W2051164729","https://openalex.org/W2054134029","https://openalex.org/W2117480088","https://openalex.org/W2125174004","https://openalex.org/W2157559660","https://openalex.org/W2273156803","https://openalex.org/W2276838857","https://openalex.org/W2547754829","https://openalex.org/W2560547898","https://openalex.org/W2589189571","https://openalex.org/W2748721266","https://openalex.org/W2750289538","https://openalex.org/W2781891680","https://openalex.org/W2791448323","https://openalex.org/W2803499602","https://openalex.org/W2890629472","https://openalex.org/W2914156600","https://openalex.org/W2940820457","https://openalex.org/W2943206593","https://openalex.org/W2958575574","https://openalex.org/W2959548514","https://openalex.org/W2969225669","https://openalex.org/W2972912275","https://openalex.org/W2998126919","https://openalex.org/W2998779857","https://openalex.org/W3027061835","https://openalex.org/W3112524236","https://openalex.org/W3127330876","https://openalex.org/W3146876044","https://openalex.org/W3164577481","https://openalex.org/W3171892222","https://openalex.org/W3173790681","https://openalex.org/W3182497194","https://openalex.org/W3206171411","https://openalex.org/W4200356220","https://openalex.org/W4210261842","https://openalex.org/W4210523115","https://openalex.org/W4285493205","https://openalex.org/W4308650771","https://openalex.org/W4382794090"],"related_works":["https://openalex.org/W2077879126","https://openalex.org/W4395698853","https://openalex.org/W2947193829","https://openalex.org/W2109755904","https://openalex.org/W4392769904","https://openalex.org/W2287025129","https://openalex.org/W2717579072","https://openalex.org/W4391599584","https://openalex.org/W2706081157","https://openalex.org/W2997910224"],"abstract_inverted_index":{"Engineering":[0],"cellular":[1],"microenvironments":[2],"with":[3,50],"biomaterials":[4],"is":[5,23,167],"an":[6,31,51],"effective":[7],"strategy":[8],"for":[9,171],"endothelial":[10,41,75,96,120,154,188],"cell":[11,76,97,101,121],"expansion":[12,37,77,98],"and":[13,38,78,90,104,109,127,133,137,143,158],"functionality":[14],"in":[15,34,74,107,110,179],"vascular":[16,26,173],"tissue":[17,149,174],"engineering.":[18],"The":[19,80],"basement":[20],"membrane":[21],"(BM)":[22],"a":[24,61,87,168],"natural":[25],"endothelium":[27],"microenvironment":[28],"that":[29,83,93,164],"plays":[30],"important":[32],"role":[33,71],"promoting":[35],"rapid":[36],"function":[39,47,122],"of":[40,48,72,129,141,187],"cells.":[42,189],"However,":[43],"mimicking":[44],"the":[45,70,113,125,139,165,184],"crucial":[46],"BM":[49,73],"ideal":[52],"biomaterial":[53,170],"remains":[54],"challenging.":[55],"In":[56],"this":[57],"study,":[58],"we":[59],"developed":[60],"cell-derived":[62],"decellularized":[63],"extracellular":[64],"matrix":[65],"(c-dECM)":[66],"paper":[67,85,116],"to":[68,182],"mimic":[69],"function.":[79],"results":[81],"showed":[82],"c-dECM":[84,115,166],"was":[86],"stable,":[88],"biocompatible,":[89],"biodegradable":[91],"scaffold":[92],"significantly":[94],"promoted":[95],"by":[99,123],"modulating":[100],"migration,":[102],"adhesion,":[103],"proliferation":[105],"both":[106],"vivo":[108],"vitro.":[111],"Moreover,":[112],"biomimetic":[114],"can":[117],"profoundly":[118],"promote":[119],"increasing":[124],"synthesis":[126],"release":[128],"nitric":[130],"oxide":[131],"(NO)":[132],"prostaglandin":[134],"I2":[135],"(PGI2)":[136],"upregulating":[138],"expression":[140],"anticoagulant":[142],"vascularized":[144],"genes,":[145],"including":[146],"thrombomodulin":[147],"(THBD),":[148],"factor":[150,156],"pathway":[151],"inhibitor":[152],"(TFPI),":[153],"growth":[155],"(VEGF)":[157],"endoglin":[159],"(CD105).":[160],"These":[161],"data":[162],"indicate":[163],"potential":[169],"constructing":[172],"engineering":[175],"scaffolds":[176],"or":[177],"developing":[178],"vitro":[180],"models":[181],"study":[183],"functional":[185],"mechanisms":[186]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}