{"id":"https://openalex.org/W4408070586","doi":"https://doi.org/10.3174/ajnr.a8545","title":"Assessment of Trigeminal Nerve Root Demyelination in Patients with Primary Trigeminal Neuralgia Using Macromolecular Proton Fraction Imaging","display_name":"Assessment of Trigeminal Nerve Root Demyelination in Patients with Primary Trigeminal Neuralgia Using Macromolecular Proton Fraction Imaging","publication_year":2025,"publication_date":"2025-02-27","ids":{"openalex":"https://openalex.org/W4408070586","doi":"https://doi.org/10.3174/ajnr.a8545","pmid":"https://pubmed.ncbi.nlm.nih.gov/40016130","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11979799"},"language":"en","primary_location":{"id":"doi:10.3174/ajnr.a8545","doi":"https://doi.org/10.3174/ajnr.a8545","is_oa":true,"landing_page_url":"https://doi.org/10.3174/ajnr.a8545","pdf_url":null,"source":{"id":"https://openalex.org/S101278519","display_name":"American Journal of Neuroradiology","issn_l":"0195-6108","issn":["0195-6108","1936-959X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316165","host_organization_name":"American Society of Neuroradiology","host_organization_lineage":["https://openalex.org/P4310316165"],"host_organization_lineage_names":["American Society of Neuroradiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Neuroradiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.3174/ajnr.a8545","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016081384","display_name":"Elena Filimonova","orcid":"https://orcid.org/0000-0002-6696-9071","observed_orcids":["https://orcid.org/0000-0002-6696-9071","https://orcid.org/0000-0002-1641-502X"]},"institutions":[{"id":"https://openalex.org/I145597306","display_name":"Novosibirsk State Medical University","ror":"https://ror.org/00d167n54","country_code":"RU","type":"education","lineage":["https://openalex.org/I145597306"]},{"id":"https://openalex.org/I4210157294","display_name":"Federal Neurosurgical Center Novosibirsk","ror":"https://ror.org/04tmsfn31","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210157294"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Elena A. Filimonova","raw_affiliation_strings":["Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia e.filimonova@alumni.nsu.ru"],"raw_orcid":"https://orcid.org/0000-0002-6696-9071","affiliations":[{"raw_affiliation_string":"Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","institution_ids":["https://openalex.org/I145597306"]},{"raw_affiliation_string":"From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia e.filimonova@alumni.nsu.ru","institution_ids":["https://openalex.org/I4210157294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029174825","display_name":"Anton A. Pashkov","orcid":"https://orcid.org/0000-0002-2403-3136","observed_orcids":["https://orcid.org/0000-0002-2403-3136"]},"institutions":[{"id":"https://openalex.org/I145597306","display_name":"Novosibirsk State Medical University","ror":"https://ror.org/00d167n54","country_code":"RU","type":"education","lineage":["https://openalex.org/I145597306"]},{"id":"https://openalex.org/I4210157294","display_name":"Federal Neurosurgical Center Novosibirsk","ror":"https://ror.org/04tmsfn31","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210157294"]},{"id":"https://openalex.org/I91727514","display_name":"Novosibirsk State Technical University","ror":"https://ror.org/01b2f6h61","country_code":"RU","type":"education","lineage":["https://openalex.org/I91727514"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Anton A. Pashkov","raw_affiliation_strings":["Department of Data Collection and Processing Systems (A.A.P.), Novosibirsk State Technical University, Novosibirsk, Russia","Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia"],"raw_orcid":"https://orcid.org/0000-0002-2403-3136","affiliations":[{"raw_affiliation_string":"Department of Data Collection and Processing Systems (A.A.P.), Novosibirsk State Technical University, Novosibirsk, Russia","institution_ids":["https://openalex.org/I91727514"]},{"raw_affiliation_string":"Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","institution_ids":["https://openalex.org/I145597306"]},{"raw_affiliation_string":"From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia","institution_ids":["https://openalex.org/I4210157294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001755868","display_name":"Vasily L. Yarnykh","orcid":"https://orcid.org/0000-0002-1583-8979","observed_orcids":["https://orcid.org/0000-0002-1583-8979"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vasily L. Yarnykh","raw_affiliation_strings":["Department of Radiology (V.L.Y.), University of Washington, Seattle, Washington"],"raw_orcid":"https://orcid.org/0000-0002-1583-8979","affiliations":[{"raw_affiliation_string":"Department of Radiology (V.L.Y.), University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109821764","display_name":"Maria I Schukina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210157294","display_name":"Federal Neurosurgical Center Novosibirsk","ror":"https://ror.org/04tmsfn31","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210157294"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Maria I. Schukina","raw_affiliation_strings":["From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia","institution_ids":["https://openalex.org/I4210157294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102984824","display_name":"Boris Zaitsev","orcid":"https://orcid.org/0000-0002-0115-3776","observed_orcids":["https://orcid.org/0000-0002-0115-3776"]},"institutions":[{"id":"https://openalex.org/I4210157294","display_name":"Federal Neurosurgical Center Novosibirsk","ror":"https://ror.org/04tmsfn31","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210157294"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Boris A. Zaitsev","raw_affiliation_strings":["From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia"],"raw_orcid":"https://orcid.org/0000-0002-0115-3776","affiliations":[{"raw_affiliation_string":"From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia","institution_ids":["https://openalex.org/I4210157294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055586023","display_name":"A. Martirosyan","orcid":"https://orcid.org/0009-0009-8603-3308","observed_orcids":["https://orcid.org/0009-0009-8603-3308"]},"institutions":[{"id":"https://openalex.org/I4210157294","display_name":"Federal Neurosurgical Center Novosibirsk","ror":"https://ror.org/04tmsfn31","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210157294"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Azniv V. Martirosyan","raw_affiliation_strings":["From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia"],"raw_orcid":"https://orcid.org/0009-0009-8603-3308","affiliations":[{"raw_affiliation_string":"From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia","institution_ids":["https://openalex.org/I4210157294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008843976","display_name":"Galina I. Moysak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145597306","display_name":"Novosibirsk State Medical University","ror":"https://ror.org/00d167n54","country_code":"RU","type":"education","lineage":["https://openalex.org/I145597306"]},{"id":"https://openalex.org/I188973947","display_name":"Novosibirsk State University","ror":"https://ror.org/04t2ss102","country_code":"RU","type":"education","lineage":["https://openalex.org/I188973947"]},{"id":"https://openalex.org/I4210157294","display_name":"Federal Neurosurgical Center Novosibirsk","ror":"https://ror.org/04tmsfn31","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210157294"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Galina I. Moysak","raw_affiliation_strings":["Department of Neuroscience (G.I.M., J.A.R.), Institute of Medicine and Psychology, Novosibirsk State University, Novosibirsk, Russia","Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience (G.I.M., J.A.R.), Institute of Medicine and Psychology, Novosibirsk State University, Novosibirsk, Russia","institution_ids":["https://openalex.org/I188973947"]},{"raw_affiliation_string":"Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","institution_ids":["https://openalex.org/I145597306"]},{"raw_affiliation_string":"From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia","institution_ids":["https://openalex.org/I4210157294"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5067434965","display_name":"JAMIL AFETOVICH RZAEV","orcid":"https://orcid.org/0000-0002-1209-8960","observed_orcids":["https://orcid.org/0000-0002-1209-8960"]},"institutions":[{"id":"https://openalex.org/I145597306","display_name":"Novosibirsk State Medical University","ror":"https://ror.org/00d167n54","country_code":"RU","type":"education","lineage":["https://openalex.org/I145597306"]},{"id":"https://openalex.org/I188973947","display_name":"Novosibirsk State University","ror":"https://ror.org/04t2ss102","country_code":"RU","type":"education","lineage":["https://openalex.org/I188973947"]},{"id":"https://openalex.org/I4210157294","display_name":"Federal Neurosurgical Center Novosibirsk","ror":"https://ror.org/04tmsfn31","country_code":"RU","type":"healthcare","lineage":["https://openalex.org/I4210157294"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Jamil A. Rzaev","raw_affiliation_strings":["Department of Neuroscience (G.I.M., J.A.R.), Institute of Medicine and Psychology, Novosibirsk State University, Novosibirsk, Russia","Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience (G.I.M., J.A.R.), Institute of Medicine and Psychology, Novosibirsk State University, Novosibirsk, Russia","institution_ids":["https://openalex.org/I188973947"]},{"raw_affiliation_string":"Department of Neurosurgery (E.A.F., A.A.P., G.I.M., J.A.R.), Novosibirsk State Medical University, Novosibirsk, Russia","institution_ids":["https://openalex.org/I145597306"]},{"raw_affiliation_string":"From the FSBI \"Federal Center of Neurosurgery,\" (E.A.F., A.A.P., M.I.S., B.A.Z., A.V.M., G.I.M., J.AR.), Novosibirsk, Russia","institution_ids":["https://openalex.org/I4210157294"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.2214,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.91595717,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"46","issue":"3","first_page":"602","last_page":"610"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12193","display_name":"Trigeminal Neuralgia and Treatments","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12193","display_name":"Trigeminal Neuralgia and Treatments","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":0.02199999988079071,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-trigeminal-neuralgia","display_name":"primary trigeminal neuralgia","score":1.0},{"id":"https://openalex.org/keywords/trigeminal-nerve-root","display_name":"trigeminal nerve root","score":0.8889999985694885},{"id":"https://openalex.org/keywords/demyelination","display_name":"demyelination","score":0.9639999866485596},{"id":"https://openalex.org/keywords/macromolecular-proton-fraction","display_name":"macromolecular proton fraction","score":0.9039999842643738},{"id":"https://openalex.org/keywords/root-entry-zone","display_name":"root entry zone","score":0.9629999995231628},{"id":"https://openalex.org/keywords/chronic-pain","display_name":"chronic pain","score":0.49399998784065247},{"id":"https://openalex.org/keywords/neuroimaging-biomarkers","display_name":"neuroimaging biomarkers","score":0.8669999837875366}],"concepts":[{"id":"https://openalex.org/C2780355897","wikidata":"https://www.wikidata.org/wiki/Q1132120","display_name":"Trigeminal neuralgia","level":2,"score":0.8845164179801941},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8150800466537476},{"id":"https://openalex.org/C2777397368","wikidata":"https://www.wikidata.org/wiki/Q189763","display_name":"Trigeminal nerve","level":2,"score":0.7474048137664795},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.5406436920166016},{"id":"https://openalex.org/C2778609137","wikidata":"https://www.wikidata.org/wiki/Q105790271","display_name":"Myelin","level":3,"score":0.5371724963188171},{"id":"https://openalex.org/C178409289","wikidata":"https://www.wikidata.org/wiki/Q674696","display_name":"Nerve root","level":2,"score":0.5324963331222534},{"id":"https://openalex.org/C2780016216","wikidata":"https://www.wikidata.org/wiki/Q1136940","display_name":"Neuralgia","level":3,"score":0.4552948772907257},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4251917004585266},{"id":"https://openalex.org/C15490471","wikidata":"https://www.wikidata.org/wiki/Q2734305","display_name":"Nociception","level":3,"score":0.4237712323665619},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.372993528842926},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.34186869859695435},{"id":"https://openalex.org/C2777107010","wikidata":"https://www.wikidata.org/wiki/Q2798704","display_name":"Neuropathic pain","level":2,"score":0.33806324005126953},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.2836635708808899},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.2789439558982849},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.23556354641914368},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.19003239274024963},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003711","descriptor_name":"Demyelinating Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011522","descriptor_name":"Protons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014276","descriptor_name":"Trigeminal Nerve","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D014277","descriptor_name":"Trigeminal Neuralgia","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.3174/ajnr.a8545","doi":"https://doi.org/10.3174/ajnr.a8545","is_oa":true,"landing_page_url":"https://doi.org/10.3174/ajnr.a8545","pdf_url":null,"source":{"id":"https://openalex.org/S101278519","display_name":"American Journal of Neuroradiology","issn_l":"0195-6108","issn":["0195-6108","1936-959X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316165","host_organization_name":"American Society of Neuroradiology","host_organization_lineage":["https://openalex.org/P4310316165"],"host_organization_lineage_names":["American Society of Neuroradiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Neuroradiology","raw_type":"journal-article"},{"id":"pmid:40016130","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40016130","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJNR. American journal of neuroradiology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11979799","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11979799/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AJNR Am J Neuroradiol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.3174/ajnr.a8545","doi":"https://doi.org/10.3174/ajnr.a8545","is_oa":true,"landing_page_url":"https://doi.org/10.3174/ajnr.a8545","pdf_url":null,"source":{"id":"https://openalex.org/S101278519","display_name":"American Journal of Neuroradiology","issn_l":"0195-6108","issn":["0195-6108","1936-959X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316165","host_organization_name":"American Society of Neuroradiology","host_organization_lineage":["https://openalex.org/P4310316165"],"host_organization_lineage_names":["American Society of Neuroradiology"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Neuroradiology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G466231879","display_name":null,"funder_award_id":"R24NS104098","funder_id":"https://openalex.org/F4320338403","funder_display_name":"Common Fund"},{"id":"https://openalex.org/G5334630427","display_name":"Quantitative myelin mapping in vivo for clinical and pre-clinical MRI","funder_award_id":"R24NS104098","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"}],"funders":[{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320338403","display_name":"Common Fund","ror":"https://ror.org/001d55x84"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":49,"referenced_works":["https://openalex.org/W1570468644","https://openalex.org/W1973394048","https://openalex.org/W1986629806","https://openalex.org/W1994958406","https://openalex.org/W2016465526","https://openalex.org/W2027347323","https://openalex.org/W2041953078","https://openalex.org/W2052963366","https://openalex.org/W2055070577","https://openalex.org/W2072310078","https://openalex.org/W2097387720","https://openalex.org/W2120654099","https://openalex.org/W2125949116","https://openalex.org/W2148144077","https://openalex.org/W2165156522","https://openalex.org/W2284939521","https://openalex.org/W2308494801","https://openalex.org/W2518974118","https://openalex.org/W2608116788","https://openalex.org/W2769724041","https://openalex.org/W2771031008","https://openalex.org/W2787346121","https://openalex.org/W2790513241","https://openalex.org/W2794155677","https://openalex.org/W2942854058","https://openalex.org/W2955015872","https://openalex.org/W2964633496","https://openalex.org/W2974667427","https://openalex.org/W2977424783","https://openalex.org/W2986186135","https://openalex.org/W2989646803","https://openalex.org/W3062821267","https://openalex.org/W3087738204","https://openalex.org/W3093211503","https://openalex.org/W3093955191","https://openalex.org/W3103756113","https://openalex.org/W3169330951","https://openalex.org/W3177601553","https://openalex.org/W3195020001","https://openalex.org/W4200265583","https://openalex.org/W4211047836","https://openalex.org/W4220728376","https://openalex.org/W4221086798","https://openalex.org/W4312095631","https://openalex.org/W4353082936","https://openalex.org/W4378772093","https://openalex.org/W4379052231","https://openalex.org/W4387741798","https://openalex.org/W4387978279"],"related_works":["https://openalex.org/W4386713504","https://openalex.org/W4353082936","https://openalex.org/W2094715106","https://openalex.org/W2974667427","https://openalex.org/W7161164270","https://openalex.org/W4285493830","https://openalex.org/W4361293402","https://openalex.org/W4378231629","https://openalex.org/W2330302509","https://openalex.org/W4401515908"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,88],"PURPOSE:":[2],"Primary":[3],"trigeminal":[4,24,52,129,181,220,310],"neuralgia":[5],"(PTN)":[6],"is":[7,15,78],"a":[8,71,82,92,242,305],"prevalent":[9],"chronic":[10],"pain":[11],"disorder.":[12],"This":[13],"condition":[14],"believed":[16],"to":[17,43],"be":[18],"associated":[19],"with":[20,67,98,167,191,227,256,262,316],"demyelination":[21],"of":[22,73,127,160,178,210,217,309,322],"the":[23,46,51,56,119,128,134,175,179,187,192,207,211,218,245,252,257,281],"nerve.":[25],"Previous":[26],"studies":[27,76],"in":[28,70,165,174,186,206,225,244,260,280,314],"this":[29],"field":[30],"have":[31],"focused":[32],"on":[33,251],"diffusion":[34],"tensor":[35],"imaging,":[36,116],"which":[37,117],"has":[38],"limited":[39],"sensitivity":[40],"and":[41,77,101,139,141,154,158,213,232,247,267,283,318],"specificity":[42],"myelin.":[44],"In":[45],"present":[47],"study,":[48],"we":[49,240],"assessed":[50],"nerve":[53,130,182,221,311,323],"root":[54,135,183,222,312,324],"via":[55],"macromolecular":[57],"proton":[58],"fraction":[59],"(MPF)":[60],"mapping":[61],"technique.":[62,121],"MPF":[63,120,122,152,177,208,249,278,301],"demonstrated":[64],"strong":[65],"correlations":[66],"myelin":[68,85],"histology":[69],"number":[72],"earlier":[74],"animal":[75],"currently":[79],"viewed":[80],"as":[81,133,304],"promising":[83],"clinical":[84],"biomarker.":[86],"MATERIALS":[87],"METHODS:":[89],"We":[90],"performed":[91],"prospective":[93],"case-control":[94],"study.":[95],"Fifty-six":[96],"patients":[97,166,226,261,315],"unilateral":[99],"PTN":[100,188,228,263,317],"27":[102],"healthy":[103,193],"controls":[104],"were":[105,109,145,148,162,223],"included.":[106],"All":[107],"participants":[108],"evaluated":[110,164],"by":[111],"using":[112],"high-resolution":[113],"brain":[114],"MR":[115],"included":[118],"values":[123,153,209,250,279],"from":[124],"different":[125],"parts":[126,216],"root,":[131],"such":[132],"entry":[136],"zone":[137],"(REZ)":[138],"central":[140,214],"lateral":[142],"cisternal":[143,215],"segments,":[144],"extracted.":[146],"ANCOVAs":[147],"performed.":[149],"Correlations":[150],"between":[151,277],"Sindou":[155,284],"grade,":[156],"duration,":[157],"intensity":[159],"symptoms":[161],"also":[163],"PTN.":[168],"RESULTS:":[169],"A":[170,274],"statistically":[171],"significant":[172],"decrease":[173,243],"average":[176,246],"affected":[180,219,253],"was":[184,286],"observed":[185],"group":[189,195],"compared":[190,255],"control":[194],"(P":[196,229,264],"<":[197,230,234,265,269,293],".01,":[198],"false":[199],"discovery":[200],"rate":[201],"[FDR]":[202],"corrected).":[203,238,273],"Specifically,":[204],"reductions":[205],"REZ":[212,248,282],"found":[224],".01":[231],"P":[233,268,292],".05,":[235],"respectively,":[236,271],"FDR":[237,272],"Furthermore,":[239],"identified":[241],"side":[254,259],"contralateral":[258],".05":[266],".001,":[270],"negative":[275],"correlation":[276],"grade":[285],"revealed":[287],"(R":[288],"=":[289],"\u22120.35,":[290],"adjusted":[291],".05).":[294],"CONCLUSIONS:":[295],"Our":[296],"preliminary":[297],"results":[298],"suggest":[299],"that":[300],"could":[302],"serve":[303],"new":[306],"neuroimaging":[307],"biomarker":[308],"impairment":[313],"enable":[319],"noninvasive":[320],"detection":[321],"demyelination.":[325]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-03-01T00:00:00"}