{"id":"https://openalex.org/W4408043598","doi":"https://doi.org/10.1016/j.transproceed.2025.02.021","title":"Case Report: A Unique Case of Hemophagocytic Lymphohistiocytosis in Heart Transplant","display_name":"Case Report: A Unique Case of Hemophagocytic Lymphohistiocytosis in Heart Transplant","publication_year":2025,"publication_date":"2025-02-28","ids":{"openalex":"https://openalex.org/W4408043598","doi":"https://doi.org/10.1016/j.transproceed.2025.02.021","pmid":"https://pubmed.ncbi.nlm.nih.gov/40021437"},"language":"en","primary_location":{"id":"doi:10.1016/j.transproceed.2025.02.021","doi":"https://doi.org/10.1016/j.transproceed.2025.02.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.transproceed.2025.02.021","pdf_url":null,"source":{"id":"https://openalex.org/S146061289","display_name":"Transplantation Proceedings","issn_l":"0041-1345","issn":["0041-1345","1873-2623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation Proceedings","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030938991","display_name":"BOAZ ELAD","orcid":"https://orcid.org/0000-0001-9253-2351","observed_orcids":["https://orcid.org/0000-0001-9253-2351"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Boaz Elad","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York. Electronic address: Be2335@cumc.columbia.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York. Electronic address: Be2335@cumc.columbia.edu","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081835899","display_name":"Wojciech Rzechorzek","orcid":"https://orcid.org/0000-0002-9755-0580","observed_orcids":["https://orcid.org/0000-0002-9755-0580"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wojciech Rzechorzek","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040063899","display_name":"Kelly Axsom","orcid":"https://orcid.org/0000-0001-8700-4757","observed_orcids":["https://orcid.org/0000-0001-8700-4757"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly Axsom","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002850518","display_name":"J. Fried","orcid":"https://orcid.org/0000-0001-6146-2637","observed_orcids":["https://orcid.org/0000-0001-6146-2637"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Justin Fried","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035700302","display_name":"Farhana Latif","orcid":"https://orcid.org/0000-0002-4127-656X","observed_orcids":["https://orcid.org/0000-0002-4127-656X"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farhana Latif","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026350211","display_name":"Adil Yunis","orcid":"https://orcid.org/0009-0009-8048-9902","observed_orcids":["https://orcid.org/0009-0009-8048-9902"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Adil Yunis","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049558512","display_name":"Carolyn Hennecken","orcid":"https://orcid.org/0000-0001-8816-7937","observed_orcids":["https://orcid.org/0000-0001-8816-7937"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carolyn Hennecken","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Rubin Salazar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rubin Salazar","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kyung T. Oh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kyung T. Oh","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067210686","display_name":"David L. Diuguid","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David L. Diuguid","raw_affiliation_strings":["Division of Hematology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064778715","display_name":"Andrew H. Lipsky","orcid":"https://orcid.org/0000-0002-7653-4792","observed_orcids":["https://orcid.org/0000-0002-7653-4792"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew H. Lipsky","raw_affiliation_strings":["Division of Hematology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029670586","display_name":"Ron S. Gejman","orcid":"https://orcid.org/0000-0001-5138-2772","observed_orcids":["https://orcid.org/0000-0001-5138-2772"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ron S. Gejman","raw_affiliation_strings":["Division of Hematology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059748572","display_name":"GABRIEL T. SAYER","orcid":"https://orcid.org/0000-0003-1701-1593","observed_orcids":["https://orcid.org/0000-0003-1701-1593"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabriel Sayer","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108984323","display_name":"Nir Uriel","orcid":"https://orcid.org/0000-0003-2301-3587","observed_orcids":["https://orcid.org/0000-0003-2301-3587"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nir Uriel","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026385784","display_name":"Dor Lotan","orcid":"https://orcid.org/0000-0003-3501-6259","observed_orcids":["https://orcid.org/0000-0003-3501-6259"]},"institutions":[{"id":"https://openalex.org/I2799503643","display_name":"Columbia University Irving Medical Center","ror":"https://ror.org/01esghr10","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799503643"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dor Lotan","raw_affiliation_strings":["Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York, New York","institution_ids":["https://openalex.org/I2799503643"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030938991"],"corresponding_institution_ids":["https://openalex.org/I2799503643"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":null,"fwci":0.7341,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.67483787,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"57","issue":"3","first_page":"481","last_page":"484"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11892","display_name":"Kawasaki Disease and Coronary Complications","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hemophagocytic-lymphohistiocytosis","display_name":"hemophagocytic lymphohistiocytosis","score":1.0},{"id":"https://openalex.org/keywords/heart-transplantation","display_name":"heart transplantation","score":0.9380000233650208},{"id":"https://openalex.org/keywords/transplant-recipients","display_name":"transplant recipients","score":0.878000020980835},{"id":"https://openalex.org/keywords/diagnostic-challenges","display_name":"diagnostic challenges","score":0.7099999785423279},{"id":"https://openalex.org/keywords/treatment","display_name":"treatment","score":0.39399999380111694},{"id":"https://openalex.org/keywords/solid-organ-transplantation","display_name":"solid organ transplantation","score":0.5090000033378601}],"concepts":[{"id":"https://openalex.org/C2779079688","wikidata":"https://www.wikidata.org/wiki/Q1642170","display_name":"Hemophagocytic lymphohistiocytosis","level":3,"score":0.930006206035614},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6515876054763794},{"id":"https://openalex.org/C2778849806","wikidata":"https://www.wikidata.org/wiki/Q643396","display_name":"Heart transplantation","level":3,"score":0.5832749605178833},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3759109377861023},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.335999071598053},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.3206735849380493},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.2218119204044342},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.22161856293678284},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007166","descriptor_name":"Immunosuppressive Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D016027","descriptor_name":"Heart Transplantation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051359","descriptor_name":"Lymphohistiocytosis, Hemophagocytic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D051359","descriptor_name":"Lymphohistiocytosis, Hemophagocytic","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D051359","descriptor_name":"Lymphohistiocytosis, Hemophagocytic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.transproceed.2025.02.021","doi":"https://doi.org/10.1016/j.transproceed.2025.02.021","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.transproceed.2025.02.021","pdf_url":null,"source":{"id":"https://openalex.org/S146061289","display_name":"Transplantation Proceedings","issn_l":"0041-1345","issn":["0041-1345","1873-2623"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation Proceedings","raw_type":"journal-article"},{"id":"pmid:40021437","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40021437","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation proceedings","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1505641753","https://openalex.org/W2035096572","https://openalex.org/W2122192183","https://openalex.org/W2144725748","https://openalex.org/W2160603395","https://openalex.org/W2162251899","https://openalex.org/W2399831781","https://openalex.org/W2790210283","https://openalex.org/W2936019126","https://openalex.org/W3021451475","https://openalex.org/W3037641470","https://openalex.org/W4385665034","https://openalex.org/W4391482066"],"related_works":["https://openalex.org/W7202080656","https://openalex.org/W4394719306","https://openalex.org/W3021451475","https://openalex.org/W4391482066","https://openalex.org/W2412518025","https://openalex.org/W3177043102","https://openalex.org/W4406688579","https://openalex.org/W2076378703","https://openalex.org/W3136247711","https://openalex.org/W4402320910"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-03-01T00:00:00"}