{"id":"https://openalex.org/W4407974971","doi":"https://doi.org/10.1016/j.jtct.2025.01.788","title":"Charting New Courses: Enhancing Clinical Research Knowledge and Confidence in Stem Cell Transplant and Cellular Therapy-Specialized Advanced Practice Providers","display_name":"Charting New Courses: Enhancing Clinical Research Knowledge and Confidence in Stem Cell Transplant and Cellular Therapy-Specialized Advanced Practice Providers","publication_year":2025,"publication_date":"2025-02-01","ids":{"openalex":"https://openalex.org/W4407974971","doi":"https://doi.org/10.1016/j.jtct.2025.01.788"},"language":"en","primary_location":{"id":"doi:10.1016/j.jtct.2025.01.788","doi":"https://doi.org/10.1016/j.jtct.2025.01.788","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtct.2025.01.788","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation and Cellular Therapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.jtct.2025.01.788","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080349897","display_name":"Theresa A. Elko","orcid":"https://orcid.org/0000-0001-8177-5788","observed_orcids":["https://orcid.org/0000-0001-8177-5788"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Theresa A. Elko","raw_affiliation_strings":["Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108696718","display_name":"Nicole J. LeStrange","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole J. LeStrange","raw_affiliation_strings":["Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029786779","display_name":"Kelly Haviland","orcid":"https://orcid.org/0000-0001-5667-0407","observed_orcids":["https://orcid.org/0000-0001-5667-0407"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly Haviland","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091811994","display_name":"Nicole Zakak","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Zakak","raw_affiliation_strings":["Department of Pediatrics, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082333371","display_name":"Miguel\u2010Angel Perales","orcid":"https://orcid.org/0000-0002-5910-4571","observed_orcids":["https://orcid.org/0000-0002-5910-4571"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Miguel-Angel Perales","raw_affiliation_strings":["Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101838284","display_name":"Jae H. Park","orcid":"https://orcid.org/0000-0002-2903-5130","observed_orcids":["https://orcid.org/0000-0002-2903-5130","https://orcid.org/0009-0003-2678-9513"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jae H Park","raw_affiliation_strings":["Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021595775","display_name":"Gunjan L. Shah","orcid":"https://orcid.org/0000-0002-9977-0456","observed_orcids":["https://orcid.org/0000-0002-9977-0456"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gunjan L. Shah","raw_affiliation_strings":["Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060701531","display_name":"Sham Mailankody","orcid":"https://orcid.org/0000-0002-2815-9561","observed_orcids":["https://orcid.org/0000-0002-2815-9561"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sham Mailankody","raw_affiliation_strings":["Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cellular Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5080349897"],"corresponding_institution_ids":["https://openalex.org/I1334819555"],"apc_list":{"value":3650,"currency":"USD","value_usd":3650},"apc_paid":{"value":3650,"currency":"USD","value_usd":3650},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04168204,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"31","issue":"2","first_page":"S495","last_page":"S496"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12168","display_name":"Health and Medical Research Impacts","score":0.7304999828338623,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12168","display_name":"Health and Medical Research Impacts","score":0.7304999828338623,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10582","display_name":"Ethics in Clinical Research","score":0.13819999992847443,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10254","display_name":"Innovations in Medical Education","score":0.05380000174045563,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/advanced-practice-providers","display_name":"advanced practice providers","score":0.890999972820282},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.8220000267028809},{"id":"https://openalex.org/keywords/cell-therapy","display_name":"cell therapy","score":0.996999979019165},{"id":"https://openalex.org/keywords/clinical-research-education","display_name":"clinical research education","score":0.8489999771118164},{"id":"https://openalex.org/keywords/clinical-trial-knowledge","display_name":"clinical trial knowledge","score":0.5009999871253967},{"id":"https://openalex.org/keywords/provider-confidence","display_name":"provider confidence","score":0.7860000133514404},{"id":"https://openalex.org/keywords/serious-adverse-events","display_name":"serious adverse events","score":0.9259999990463257},{"id":"https://openalex.org/keywords/informed-consent","display_name":"informed consent","score":0.8389999866485596},{"id":"https://openalex.org/keywords/regulatory-aspects","display_name":"regulatory considerations","score":0.6869999766349792},{"id":"https://openalex.org/keywords/clinical-documentation","display_name":"clinical documentation","score":0.625},{"id":"https://openalex.org/keywords/concomitant-medications","display_name":"concomitant medications","score":0.824999988079071},{"id":"https://openalex.org/keywords/research-team-roles","display_name":"research team roles","score":0.6819999814033508},{"id":"https://openalex.org/keywords/educational-intervention","display_name":"educational intervention","score":0.47699999809265137},{"id":"https://openalex.org/keywords/knowledge-assessment","display_name":"knowledge assessment","score":0.6269999742507935},{"id":"https://openalex.org/keywords/cancer-clinical-trials","display_name":"cancer clinical trials","score":0.45899999141693115},{"id":"https://openalex.org/keywords/memorial-sloan-kettering-cancer-center","display_name":"Memorial Sloan-Kettering Cancer Center","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5214223861694336},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4794161021709442},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.4587095379829407},{"id":"https://openalex.org/C509550671","wikidata":"https://www.wikidata.org/wiki/Q126945","display_name":"Medical education","level":1,"score":0.38610953092575073},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.25822749733924866},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0911293625831604},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jtct.2025.01.788","doi":"https://doi.org/10.1016/j.jtct.2025.01.788","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtct.2025.01.788","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation and Cellular Therapy","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.jtct.2025.01.788","doi":"https://doi.org/10.1016/j.jtct.2025.01.788","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jtct.2025.01.788","pdf_url":null,"source":{"id":"https://openalex.org/S59987174","display_name":"Transplantation and Cellular Therapy","issn_l":"1083-8791","issn":["1083-8791","1523-6536","2666-6367"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation and Cellular Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2163093563","https://openalex.org/W3000884967","https://openalex.org/W4407975024","https://openalex.org/W4366964853","https://openalex.org/W3175398433","https://openalex.org/W3187077720","https://openalex.org/W3148779133","https://openalex.org/W7127329886","https://openalex.org/W2951042325","https://openalex.org/W4360979112"],"abstract_inverted_index":{"Introduction":[0],"Hematopoietic":[1],"cell":[2],"transplant":[3],"(HCT)":[4],"and":[5,47,52,89,93,104,146,150,167,189,193,199,207,219,236,295,304,311,324,373],"cellular":[6],"therapy":[7],"(CT)":[8],"is":[9,69],"a":[10,16,70,116,253,289,384],"rapidly":[11],"evolving":[12],"clinical":[13,21,48,76,96,124,137,360,371,385],"area":[14],"with":[15],"high":[17],"volume":[18],"of":[19,123,160,230,261,298,326,336,370,380],"ongoing":[20],"research":[22,77,97,147,361],".":[23],"Memorial":[24],"Sloan":[25],"Kettering":[26],"Cancer":[27],"Center":[28],"(MSKCC)":[29],"currently":[30],"offers":[31],"approximately":[32],"60":[33],"actively":[34],"accruing":[35],"therapeutic":[36],"trials":[37,125],"in":[38,95,108,185,228,268,273,292,316,363],"HCT/CT;":[39],"most":[40],"are":[41],"high-complexity":[42],"due":[43],"to":[44,84,102,181,214,344,358],"logistical":[45],"considerations":[46,341],"toxicities":[49],"experienced.":[50],"CT":[51],"HCT":[53],"advanced":[54],"practice":[55],"providers":[56],"(APPs)":[57],"at":[58,350],"MSKCC":[59],"routinely":[60],"care":[61,372],"for":[62,73],"patients":[63,169],"receiving":[64],"investigational":[65],"treatment;":[66],"however,":[67],"there":[68],"significant":[71,272,290],"need":[72],"structured":[74],"APP":[75,91,293,348,382],"education.":[78],"Objectives":[79],"This":[80],"pilot":[81,286,354],"program":[82,287],"intended":[83],"close":[85],"the":[86,171,176,202,257,345,368,378,381],"education":[87],"gap":[88],"strengthen":[90,359],"knowledge":[92,153,191,216,248,294,310,337],"confidence":[94,177,184,194,220,237,269,312],"by":[98,163],"providing":[99],"formal":[100],"training":[101],"outpatient":[103],"inpatient":[105],"APPs":[106],"practicing":[107],"HCT/CT":[109,172],"(n":[110],"=":[111],"23).":[112],"Methods":[113],"Participants":[114],"viewed":[115],"35-minute":[117],"recorded":[118],"lecture":[119],"covering":[120],"many":[121],"domains":[122,240],"operations":[126],"including:":[127],"serious":[128,279],"adverse":[129,132,280,305],"events":[130,133,281,306],",":[131,134,141,307,330],"regulatory":[135],"considerations,":[136],"documentation,":[138],"informed":[139],"consent":[140],"protocol":[142,302],"navigation,":[143],"concomitant":[144],"medications,":[145],"team":[148],"roles":[149],"responsibilities.":[151],"The":[152,244,285],"assessment":[154,217,249,338],"included":[155,301,320],"ten":[156],"questions":[157,233],"assessing":[158],"understanding":[159],"each":[161,186],"domain":[162],"incorporating":[164],"example":[165],"protocols":[166],"mock":[168],"from":[170,256],"patient":[173],"population,":[174],"while":[175,376],"survey":[178,221],"asked":[179],"participants":[180],"assess":[182],"their":[183],"domain.":[187],"Pre-intervention":[188],"post-intervention":[190,247],"assessments":[192],"surveys":[195],"were":[196,212,251,313],"administered":[197],"before":[198],"after":[200],"viewing":[201],"educational":[203],"module.":[204],"Paired":[205],"T-Tests":[206],"Wilcoxon":[208],"Ranked":[209],"Sum":[210],"Tests":[211],"employed":[213],"compare":[215],"scores":[218,226,250],"responses,":[222],"respectively.":[223],"Results":[224],"Knowledge":[225],"increased":[227],"9":[229],"10":[231],"measured":[232,276],"(Figure":[234,242,265,282],"1)":[235],"across":[238],"all":[239,275],"improved":[241],"3).":[243],"mean":[245,258],"overall":[246],"77.4%,":[252],"52.1%":[254],"improvement":[255,300],"baseline":[259,309],"score":[260],"50.9%":[262],"(p":[263],"<0.01)":[264],"1).":[266],"Increase":[267],"ratings":[270],"was":[271],"nearly":[274],"domains,":[277],"excepting":[278],"2).":[283],"Conclusions":[284],"demonstrated":[288],"increase":[291],"confidence.":[296],"Areas":[297],"least":[299],"navigation":[303],"though":[308],"above":[314],"average":[315],"these":[317],"domains.":[318],"Limitations":[319],"small":[321],"sample":[322],"size":[323],"lack":[325],"instrument":[327],"construct":[328],"validity":[329],"which":[331],"may":[332],"have":[333],"influenced":[334],"difficulty":[335],"questions.":[339],"Future":[340],"include":[342],"expanding":[343],"broader":[346],"oncology":[347],"population":[349],"MSKCC.":[351],"Overall,":[352],"this":[353],"highlights":[355],"an":[356],"opportunity":[357],"proficiency":[362],"HCT/CT-specialized":[364],"APPs,":[365],"potentially":[366],"improving":[367],"quality":[369],"data":[374],"collection":[375],"advancing":[377],"role":[379],"as":[383],"trial":[386],"investigator.":[387]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2025-02-27T00:00:00"}