{"id":"https://openalex.org/W4407962529","doi":"https://doi.org/10.1007/s10067-025-07378-z","title":"Risk factors for poor prognosis in ANCA-associated vasculitis with interstitial lung disease: a systematic review and meta-analysis","display_name":"Risk factors for poor prognosis in ANCA-associated vasculitis with interstitial lung disease: a systematic review and meta-analysis","publication_year":2025,"publication_date":"2025-02-26","ids":{"openalex":"https://openalex.org/W4407962529","doi":"https://doi.org/10.1007/s10067-025-07378-z","pmid":"https://pubmed.ncbi.nlm.nih.gov/40011357"},"language":"en","primary_location":{"id":"doi:10.1007/s10067-025-07378-z","doi":"https://doi.org/10.1007/s10067-025-07378-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10067-025-07378-z","pdf_url":null,"source":{"id":"https://openalex.org/S44888363","display_name":"Clinical Rheumatology","issn_l":"0770-3198","issn":["0770-3198","1434-9949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Rheumatology","raw_type":"journal-article"},"volume":null,"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1007/s10067-025-07378-z","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100637067","display_name":"Xing He","orcid":"https://orcid.org/0009-0003-8209-3692","observed_orcids":["https://orcid.org/0009-0003-8209-3692"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xing He","raw_affiliation_strings":["Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China","State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonary and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]},{"raw_affiliation_string":"State Key Laboratory of Respiratory Health and Multimorbidity, West China Hospital, Sichuan University, Chengdu, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Weiwei Yuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Weiwei Yuan","raw_affiliation_strings":["School of Medicine, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yahui Yang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118397","display_name":"Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital","ror":"https://ror.org/01qh26a66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yahui Yang","raw_affiliation_strings":["Department of Pulmonary and Critical Care Medicine, School of Medicine, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonary and Critical Care Medicine, School of Medicine, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101885710","display_name":"Jiaqi Ji","orcid":"https://orcid.org/0000-0002-2190-9040","observed_orcids":["https://orcid.org/0000-0002-2190-9040"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118397","display_name":"Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital","ror":"https://ror.org/01qh26a66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaqi Ji","raw_affiliation_strings":["Department of Pulmonary and Critical Care Medicine, School of Medicine, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pulmonary and Critical Care Medicine, School of Medicine, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118397"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016580701","display_name":"Xixi Chen","orcid":"https://orcid.org/0009-0009-4085-5875","observed_orcids":["https://orcid.org/0009-0009-4085-5875"]},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]},{"id":"https://openalex.org/I4210118397","display_name":"Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital","ror":"https://ror.org/01qh26a66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210118397"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xixi Chen","raw_affiliation_strings":["Department of Rheumatology and Immunology, Qionglai Medical Center Hospital, Chengdu, China. 18981838212@163.com","Department of Rheumatology and Immunology, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China. 18981838212@163.com","Department of Rheumatology and Immunology, Qionglai Medical Center Hospital, Chengdu, China","Department of Rheumatology and Immunology, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China"],"raw_orcid":"https://orcid.org/0009-0009-4085-5875","affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Immunology, Qionglai Medical Center Hospital, Chengdu, China. 18981838212@163.com","institution_ids":[]},{"raw_affiliation_string":"Department of Rheumatology and Immunology, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China. 18981838212@163.com","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118397"]},{"raw_affiliation_string":"Department of Rheumatology and Immunology, Qionglai Medical Center Hospital, Chengdu, China","institution_ids":[]},{"raw_affiliation_string":"Department of Rheumatology and Immunology, Sichuan Provincial People'S Hospital, University of Electronic Science and Technology of China, Chengdu, China","institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118397"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5016580701"],"corresponding_institution_ids":["https://openalex.org/I150229711","https://openalex.org/I4210118397"],"apc_list":{"value":4890,"currency":"USD","value_usd":4890},"apc_paid":{"value":4890,"currency":"USD","value_usd":4890},"fwci":1.6839,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.82712063,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":"44","issue":"4","first_page":"1675","last_page":"1689"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10697","display_name":"Vasculitis and related conditions","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10870","display_name":"Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/anca-associated-vasculitis","display_name":"ANCA-associated vasculitis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/interstitial-lung-disease","display_name":"interstitial lung disease","score":0.9079999923706055},{"id":"https://openalex.org/keywords/risk-factors-for-mortality","display_name":"mortality risk factors","score":0.9259999990463257},{"id":"https://openalex.org/keywords/prognosis","display_name":"prognosis","score":0.5889999866485596},{"id":"https://openalex.org/keywords/usual-interstitial-pneumonia-pattern","display_name":"usual interstitial pneumonia pattern","score":0.8820000290870667},{"id":"https://openalex.org/keywords/acute-exacerbation","display_name":"acute exacerbation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/microscopic-polyangiitis","display_name":"microscopic polyangiitis","score":0.9929999709129333},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.7419999837875366},{"id":"https://openalex.org/keywords/forced-vital-capacity","display_name":"forced vital capacity","score":0.8240000009536743},{"id":"https://openalex.org/keywords/induction-immunosuppression","display_name":"induction immunosuppression","score":0.8880000114440918},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.4000000059604645},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6809999942779541},{"id":"https://openalex.org/keywords/neurological-involvement","display_name":"neurological involvement","score":0.8709999918937683},{"id":"https://openalex.org/keywords/pulmonary-arterial-hypertension","display_name":"pulmonary arterial hypertension","score":0.8820000290870667}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9491081237792969},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7783544659614563},{"id":"https://openalex.org/C2777543607","wikidata":"https://www.wikidata.org/wiki/Q1153419","display_name":"Interstitial lung disease","level":3,"score":0.6802412271499634},{"id":"https://openalex.org/C2778910314","wikidata":"https://www.wikidata.org/wiki/Q1934069","display_name":"Microscopic polyangiitis","level":4,"score":0.6645126342773438},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6236041188240051},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.6232418417930603},{"id":"https://openalex.org/C2781229154","wikidata":"https://www.wikidata.org/wiki/Q1161568","display_name":"Granulomatosis with polyangiitis","level":4,"score":0.5621764659881592},{"id":"https://openalex.org/C2777014857","wikidata":"https://www.wikidata.org/wiki/Q1383410","display_name":"Exacerbation","level":2,"score":0.4577364921569824},{"id":"https://openalex.org/C198451711","wikidata":"https://www.wikidata.org/wiki/Q327657","display_name":"Rheumatology","level":2,"score":0.4457875192165375},{"id":"https://openalex.org/C2776015282","wikidata":"https://www.wikidata.org/wiki/Q644318","display_name":"Vasculitis","level":3,"score":0.43091708421707153},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.4229426383972168},{"id":"https://openalex.org/C24040308","wikidata":"https://www.wikidata.org/wiki/Q574727","display_name":"Anti-neutrophil cytoplasmic antibody","level":4,"score":0.41571447253227234},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.2682703137397766},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.19721093773841858}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D017563","descriptor_name":"Lung Diseases, Interstitial","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D056648","descriptor_name":"Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10067-025-07378-z","doi":"https://doi.org/10.1007/s10067-025-07378-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10067-025-07378-z","pdf_url":null,"source":{"id":"https://openalex.org/S44888363","display_name":"Clinical Rheumatology","issn_l":"0770-3198","issn":["0770-3198","1434-9949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Rheumatology","raw_type":"journal-article"},{"id":"pmid:40011357","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40011357","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical rheumatology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11993495","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11993495","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11993495/pdf/10067_2025_Article_7378.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clin Rheumatol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s10067-025-07378-z","doi":"https://doi.org/10.1007/s10067-025-07378-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10067-025-07378-z","pdf_url":null,"source":{"id":"https://openalex.org/S44888363","display_name":"Clinical Rheumatology","issn_l":"0770-3198","issn":["0770-3198","1434-9949"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Rheumatology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8700000047683716}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W2031517139","https://openalex.org/W2116475791","https://openalex.org/W2119214281","https://openalex.org/W2133864205","https://openalex.org/W2149661971","https://openalex.org/W2153580086","https://openalex.org/W2164028635","https://openalex.org/W2504434315","https://openalex.org/W2604367936","https://openalex.org/W2765693228","https://openalex.org/W2889197569","https://openalex.org/W2975102008","https://openalex.org/W3012399189","https://openalex.org/W3016472229","https://openalex.org/W3124227772","https://openalex.org/W3128175276","https://openalex.org/W3132256081","https://openalex.org/W3136002278","https://openalex.org/W3155915809","https://openalex.org/W4223903511","https://openalex.org/W4281398652","https://openalex.org/W4282836477","https://openalex.org/W4301183288","https://openalex.org/W4311096877","https://openalex.org/W4317861117","https://openalex.org/W4318457100","https://openalex.org/W4367049102","https://openalex.org/W4375862704","https://openalex.org/W4386195864","https://openalex.org/W4386271584","https://openalex.org/W4387703250","https://openalex.org/W4401550793","https://openalex.org/W4402288540"],"related_works":["https://openalex.org/W3025812947","https://openalex.org/W3032075507","https://openalex.org/W2258178867","https://openalex.org/W4232151264","https://openalex.org/W2578237584","https://openalex.org/W3081393921","https://openalex.org/W1912084238","https://openalex.org/W2897514451","https://openalex.org/W2954192426","https://openalex.org/W2021909779"],"abstract_inverted_index":{"OBJECTIVE:":[0],"Antineutrophil":[1],"cytoplasm":[2],"antibody-associated":[3],"vasculitis":[4],"(AAV)":[5],"with":[6,29,40,44,132,145,208,239,286,291,348,416,456,461],"interstitial":[7,180,333,400],"lung":[8],"disease":[9],"(AAV-ILD)":[10],"is":[11],"the":[12,18,22,36,114,136,153,300,311,316,371],"main":[13],"manifestation":[14],"of":[15,24,49,84,116,142,156,212,243,305,370,395,421],"AAV":[16,65],"involving":[17],"lung,":[19],"further":[20],"increasing":[21],"risk":[23,37,86,102,158,211,242,288,342,372,409],"poor":[25,387,412,437,457],"prognosis":[26,388,413,458],"in":[27,42,88,147,289,346,389,414,459],"patients":[28,43,144,290,347,415,460],"AAV.":[30],"This":[31],"study":[32],"aimed":[33],"to":[34,112,385],"investigate":[35],"factors":[38,87,343,364,373,410,435],"associated":[39,207,238],"mortality":[41,157,287,345],"AAV-ILD.":[45,292,417,462],"METHODS:":[46],"In":[47],"Web":[48],"Science,":[50],"PubMed,":[51],"Embase":[52],"and":[53,66,79,92,107,127,135,197,227,270,310,321,338,356,383,405,427,446],"Scopus":[54],"databases,":[55],"a":[56,240],"comprehensive":[57],"search":[58],"was":[59,121,130],"performed":[60],"for":[61,152,229,344,359,374,379,411,430],"English":[62],"studies":[63,149],"on":[64,99],"ILD":[67],"published":[68],"from":[69],"inception":[70],"date":[71],"until":[72],"May":[73],"17,":[74],"2024.":[75],"Hazard":[76],"ratios":[77],"(HR)":[78],"95%":[80],"confidence":[81],"intervals":[82],"(CI)":[83],"mortality-related":[85],"AAV-ILD":[89,146,213,244,375],"were":[90,95,110,150,206,237,319,341,408],"collected,":[91],"subgroup":[93],"analyses":[94,326],"carried":[96],"out":[97],"based":[98],"different":[100],"candidate":[101],"factors.":[103,159],"Cochran's":[104],"Q":[105],"statistic":[106],"inconsistency":[108],"value":[109],"utilized":[111],"assess":[113],"heterogeneity":[115,298],"included":[117,151],"studies.":[118,302],"Sensitivity":[119],"analysis":[120,155],"executed":[122],"using":[123],"one-by-one":[124],"elimination":[125],"method,":[126],"publication":[128],"bias":[129],"evaluated":[131],"Egger's":[133,308],"test":[134,294,309],"trim-and-fill":[137,312],"method.":[138],"RESULTS:":[139],"A":[140,367],"total":[141],"654":[143],"eight":[148],"pooled":[154,301,317,325],"The":[160,303,324],"results":[161,304],"showed":[162,282,452],"that":[163,315,328],"age":[164],"(HR":[165,173,183,191,200,221,231,247,256,264,276],"=":[166,174,184,192,201,222,232,248,257,265,277],"1.06,":[167],"95%CI:":[168,176,186,194,203,224,234,250,259,267,279],"1.04,":[169],"1.08),":[170],"ever":[171,330,397],"smoker":[172],"1.61,":[175],"1.13,":[177],"2.29),":[178],"usual":[179,332,399],"pneumonia":[181,334,401],"pattern":[182],"2.07,":[185],"1.43,":[187],"3.00),":[188],"acute":[189,336,403],"exacerbation":[190,337,404],"2.73,":[193],"1.70,":[195,204],"4.40)":[196],"microscopic":[198,339,406],"polyangiitis":[199,340,407],"4.03,":[202],"9.55)":[205],"an":[209],"increased":[210],"mortality.":[214,245,366],"Conversely,":[215],"percent":[216,351,422],"predicted":[217,352,423],"forced":[218,353,424],"vital":[219,354,425],"capacity":[220,355,426],"0.97,":[223,268],"0.96,":[225],"0.99)":[226],"immunosuppressant":[228,357,428],"induction":[230,360,431],"0.40,":[233],"0.28,":[235],"0.58)":[236],"reduced":[241],"Male":[246],"1.27,":[249],"0.90,":[251],"1.80),":[252],"nervous":[253,441],"system":[254,442],"involvement":[255,263,445],"0.99,":[258],"0.65,":[260],"1.52),":[261],"renal":[262,444],"1.24,":[266],"1.95)":[269],"five":[271,447],"factor":[272,448],"score":[273,449],"\u2265":[274,450],"1":[275,451],"1.00,":[278],"0.67,":[280],"1.48)":[281],"no":[283,296,453],"significant":[284,297,454],"correlation":[285,455],"Heterogeneity":[293],"indicated":[295],"among":[299],"sensitivity":[306],"analysis,":[307],"method":[313],"revealed":[314],"findings":[318],"stable":[320],"reliable.":[322],"CONCLUSION:":[323],"demonstrated":[327],"age,":[329,396],"smoker,":[331,398],"pattern,":[335,402],"AAV-ILD,":[349],"while":[350],"therapy":[358,429],"serve":[361,432],"as":[362,433],"protective":[363,434],"against":[365,436],"systematic":[368],"understanding":[369],"may":[376],"provide":[377],"clues":[378],"developing":[380],"effective":[381],"interventions":[382],"managements":[384],"improve":[386],"patients.":[390],"Key":[391],"Points":[392],"\u2022":[393,418,439],"Increase":[394],"High":[419],"level":[420],"prognosis.":[438],"Male,":[440],"involvement,":[443]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":4}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2025-10-10T00:00:00"}