{"id":"https://openalex.org/W4407923397","doi":"https://doi.org/10.3390/antiox14030258","title":"Oxidative Stress and Redox Signaling in Gastric Cancer: From Mechanisms to Therapeutic Implications","display_name":"Oxidative Stress and Redox Signaling in Gastric Cancer: From Mechanisms to Therapeutic Implications","publication_year":2025,"publication_date":"2025-02-24","ids":{"openalex":"https://openalex.org/W4407923397","doi":"https://doi.org/10.3390/antiox14030258","pmid":"https://pubmed.ncbi.nlm.nih.gov/40227215","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11939249"},"language":"en","primary_location":{"id":"doi:10.3390/antiox14030258","doi":"https://doi.org/10.3390/antiox14030258","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox14030258","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.3390/antiox14030258","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100718748","display_name":"Zehua Chen","orcid":"https://orcid.org/0000-0002-1204-679X","observed_orcids":["https://orcid.org/0000-0002-1204-679X"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zehua Chen","raw_affiliation_strings":["Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]},{"raw_affiliation_string":"Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100595189","display_name":"Jiawu Fan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiawu Fan","raw_affiliation_strings":["Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100365900","display_name":"Xiao\u2010Long Chen","orcid":"https://orcid.org/0000-0003-3796-9248","observed_orcids":["https://orcid.org/0000-0003-3796-9248"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaolong Chen","raw_affiliation_strings":["Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]},{"raw_affiliation_string":"Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109518238","display_name":"Kun Yang","orcid":"https://orcid.org/0000-0002-6232-6271","observed_orcids":["https://orcid.org/0000-0002-6232-6271"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kun Yang","raw_affiliation_strings":["Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]},{"raw_affiliation_string":"Gastric Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100342696","display_name":"Kui Wang","orcid":"https://orcid.org/0000-0003-3503-1563","observed_orcids":["https://orcid.org/0000-0003-3503-1563"]},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4391768003","display_name":"State Key Laboratory of Biotherapy","ror":"https://ror.org/00x43yy22","country_code":"CN","type":"facility","lineage":["https://openalex.org/I24185976","https://openalex.org/I4391768003"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Kui Wang","raw_affiliation_strings":["Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China"],"raw_orcid":"https://orcid.org/0000-0003-3503-1563","affiliations":[{"raw_affiliation_string":"Department of General Surgery and Laboratory of Gastric Cancer, West China School of Basic Medical Sciences & Forensic Medicine, State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100342696","https://openalex.org/A5109518238"],"corresponding_institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4391768003"],"apc_list":{"value":2900,"currency":"CHF","value_usd":3499},"apc_paid":{"value":2900,"currency":"CHF","value_usd":3499},"fwci":1.3858,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.79894147,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"14","issue":"3","first_page":"258","last_page":"258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.003000000026077032,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14135","display_name":"Cancer and biochemical research","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.8240000009536743},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":1.0},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9850000143051147},{"id":"https://openalex.org/keywords/redox-signaling","display_name":"redox signaling","score":1.0},{"id":"https://openalex.org/keywords/oxidative-post-translational-modifications","display_name":"oxidative post-translational modifications","score":0.9739999771118164},{"id":"https://openalex.org/keywords/redox-sensitive-proteins","display_name":"redox-sensitive proteins","score":0.8840000033378601},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.5709999799728394},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.7870000004768372},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7089999914169312},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.875},{"id":"https://openalex.org/keywords/bioactive-natural-products","display_name":"bioactive natural products","score":0.8500000238418579},{"id":"https://openalex.org/keywords/nanomaterials","display_name":"nanomaterials","score":0.9929999709129333}],"concepts":[{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.8637523055076599},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.6870229244232178},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6278449296951294},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.5743443965911865},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.563797116279602},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5494817495346069},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4945678412914276},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.46324148774147034},{"id":"https://openalex.org/C57600042","wikidata":"https://www.wikidata.org/wiki/Q227564","display_name":"Oxidative phosphorylation","level":2,"score":0.4631113111972809},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4488362669944763},{"id":"https://openalex.org/C150555746","wikidata":"https://www.wikidata.org/wiki/Q210973","display_name":"Cell signaling","level":3,"score":0.4358750283718109},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.4223380386829376},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2170903980731964},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.055789828300476074}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/antiox14030258","doi":"https://doi.org/10.3390/antiox14030258","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox14030258","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11939249","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11939249/","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11939249/pdf/","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants (Basel)","raw_type":"Text"},{"id":"pmid:40227215","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40227215","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:073a5aa156df4f4b8e4ea4f1efa65b71","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/073a5aa156df4f4b8e4ea4f1efa65b71","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Antioxidants, Vol 14, Iss 3, p 258 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/antiox14030258","doi":"https://doi.org/10.3390/antiox14030258","is_oa":true,"landing_page_url":"https://doi.org/10.3390/antiox14030258","pdf_url":null,"source":{"id":"https://openalex.org/S2737566431","display_name":"Antioxidants","issn_l":"2076-3921","issn":["2076-3921"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Antioxidants","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1871909649","display_name":null,"funder_award_id":"82273122","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2575135340","display_name":null,"funder_award_id":"82472926","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4286248347","display_name":null,"funder_award_id":"ZYJC21006","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7232521901","display_name":null,"funder_award_id":"2023YFS0060","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7343717211","display_name":null,"funder_award_id":"82472734","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322922","display_name":"Department of Science and Technology of Sichuan Province","ror":"https://ror.org/04323m874"},{"id":"https://openalex.org/F4320336042","display_name":"West China Hospital, Sichuan University","ror":"https://ror.org/007mrxy13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4407923397.pdf","grobid_xml":"https://content.openalex.org/works/W4407923397.grobid-xml"},"referenced_works_count":130,"referenced_works":["https://openalex.org/W264423964","https://openalex.org/W1912200205","https://openalex.org/W1973211467","https://openalex.org/W2018563185","https://openalex.org/W2032635496","https://openalex.org/W2060663826","https://openalex.org/W2088226047","https://openalex.org/W2094156327","https://openalex.org/W2100439220","https://openalex.org/W2102472842","https://openalex.org/W2110507552","https://openalex.org/W2144542772","https://openalex.org/W2154885430","https://openalex.org/W2164710273","https://openalex.org/W2342940507","https://openalex.org/W2591054253","https://openalex.org/W2621333085","https://openalex.org/W2775780002","https://openalex.org/W2777839512","https://openalex.org/W2802537769","https://openalex.org/W2886983241","https://openalex.org/W2904981116","https://openalex.org/W2920950064","https://openalex.org/W2939714203","https://openalex.org/W2945012199","https://openalex.org/W2945459534","https://openalex.org/W2949213103","https://openalex.org/W2953317809","https://openalex.org/W2954941033","https://openalex.org/W2959353994","https://openalex.org/W2965249906","https://openalex.org/W2967859001","https://openalex.org/W2971379494","https://openalex.org/W2993914509","https://openalex.org/W3003977949","https://openalex.org/W3007316551","https://openalex.org/W3008806016","https://openalex.org/W3010682239","https://openalex.org/W3013352992","https://openalex.org/W3028737550","https://openalex.org/W3040553139","https://openalex.org/W3082676535","https://openalex.org/W3092152431","https://openalex.org/W3098441039","https://openalex.org/W3129009349","https://openalex.org/W3129551551","https://openalex.org/W3130927306","https://openalex.org/W3138811052","https://openalex.org/W3156139743","https://openalex.org/W3158672854","https://openalex.org/W3166825619","https://openalex.org/W3171517418","https://openalex.org/W3187083095","https://openalex.org/W3197613986","https://openalex.org/W3198675921","https://openalex.org/W3198882630","https://openalex.org/W3201161912","https://openalex.org/W3206881002","https://openalex.org/W4200297140","https://openalex.org/W4205417690","https://openalex.org/W4206662285","https://openalex.org/W4220732139","https://openalex.org/W4220826664","https://openalex.org/W4220922773","https://openalex.org/W4223530786","https://openalex.org/W4224248664","https://openalex.org/W4225396980","https://openalex.org/W4226031933","https://openalex.org/W4229374749","https://openalex.org/W4281616163","https://openalex.org/W4281670278","https://openalex.org/W4283382780","https://openalex.org/W4283585651","https://openalex.org/W4284889683","https://openalex.org/W4285105720","https://openalex.org/W4286219756","https://openalex.org/W4294243416","https://openalex.org/W4295122483","https://openalex.org/W4306909237","https://openalex.org/W4308958733","https://openalex.org/W4311863294","https://openalex.org/W4312066391","https://openalex.org/W4312066787","https://openalex.org/W4313528225","https://openalex.org/W4313825915","https://openalex.org/W4317359127","https://openalex.org/W4318669187","https://openalex.org/W4319013643","https://openalex.org/W4321436242","https://openalex.org/W4321599925","https://openalex.org/W4360611401","https://openalex.org/W4367396558","https://openalex.org/W4380684792","https://openalex.org/W4381309526","https://openalex.org/W4381469200","https://openalex.org/W4384155394","https://openalex.org/W4386390376","https://openalex.org/W4386498846","https://openalex.org/W4387739926","https://openalex.org/W4387746953","https://openalex.org/W4387930898","https://openalex.org/W4388997616","https://openalex.org/W4389262634","https://openalex.org/W4389624403","https://openalex.org/W4389956278","https://openalex.org/W4390350758","https://openalex.org/W4390636085","https://openalex.org/W4390988980","https://openalex.org/W4391042325","https://openalex.org/W4391112647","https://openalex.org/W4392360973","https://openalex.org/W4392752475","https://openalex.org/W4393203599","https://openalex.org/W4393935425","https://openalex.org/W4394590251","https://openalex.org/W4396765847","https://openalex.org/W4396841314","https://openalex.org/W4400450663","https://openalex.org/W4401304679","https://openalex.org/W4401634998","https://openalex.org/W4402035837","https://openalex.org/W4402091987","https://openalex.org/W4402292850","https://openalex.org/W4402489635","https://openalex.org/W4403360366","https://openalex.org/W4403718851","https://openalex.org/W4404468177","https://openalex.org/W4404718409","https://openalex.org/W4405946111","https://openalex.org/W4406967815"],"related_works":["https://openalex.org/W7171224139","https://openalex.org/W4366292802","https://openalex.org/W4400458001","https://openalex.org/W3143061976","https://openalex.org/W2516808813","https://openalex.org/W4385334687","https://openalex.org/W2914485225","https://openalex.org/W4363674202","https://openalex.org/W4409454957","https://openalex.org/W4200185093"],"abstract_inverted_index":{"Oxidative":[0],"stress,":[1],"which":[2,86],"is":[3],"characterized":[4],"by":[5],"an":[6,33,167],"imbalance":[7],"between":[8],"reactive":[9],"oxygen":[10],"species":[11],"(ROS)":[12],"production":[13],"and":[14,24,40,55,65,92,107,140,176],"antioxidant":[15],"defenses,":[16],"has":[17,73],"critical":[18],"roles":[19,143],"in":[20,67,96,110,133,147],"the":[21,30,45,101,128,135,142,161,170],"initiation,":[22],"progression,":[23],"treatment":[25,162],"of":[26,50,57,83,104,130,137,144,163,172],"gastric":[27,68,111,138,148,164],"cancer.":[28,69,149],"On":[29,44],"one":[31],"hand,":[32,47],"excessive":[34],"ROS":[35,51,76],"accumulation":[36],"induces":[37],"oxidative":[38,79,105,131,158],"damage":[39],"cancer":[41,97,112,139],"cell":[42],"death.":[43],"other":[46],"moderate":[48],"levels":[49],"cause":[52],"genetic":[53],"mutations":[54],"dysregulation":[56],"signaling":[58,95,109],"pathways":[59],"to":[60,116],"promote":[61],"proliferation,":[62],"inflammation,":[63],"angiogenesis,":[64],"metastasis":[66],"Notably,":[70],"emerging":[71,155],"evidence":[72],"revealed":[74],"that":[75],"also":[77],"mediate":[78],"post-translational":[80],"modifications":[81],"(oxPTMs)":[82],"redox-sensitive":[84],"proteins,":[85],"can":[87],"directly":[88],"affect":[89],"protein":[90],"functions":[91],"regulate":[93],"redox":[94,108],"cells.":[98],"Therefore,":[99],"elucidating":[100],"regulatory":[102],"mechanisms":[103,129],"stress":[106,132,159],"holds":[113],"great":[114],"promise":[115],"identify":[117],"novel":[118],"therapeutic":[119],"targets":[120],"or":[121],"redox-targeting":[122],"strategies.":[123],"This":[124],"review":[125],"will":[126,153],"summarize":[127],"regulating":[134],"hallmarks":[136],"highlight":[141],"ROS-mediated":[145],"oxPTMs":[146],"In":[150],"addition,":[151],"we":[152],"discuss":[154],"strategies":[156],"targeting":[157],"for":[160],"cancer,":[165],"with":[166],"emphasis":[168],"on":[169],"use":[171],"bioactive":[173],"natural":[174],"products":[175],"nanomaterials.":[177]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2025-02-26T00:00:00"}
