{"id":"https://openalex.org/W4407899223","doi":"https://doi.org/10.14529/food240210","title":"The biopotential of trans-cinnamic acid","display_name":"The biopotential of trans-cinnamic acid","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4407899223","doi":"https://doi.org/10.14529/food240210"},"language":"en","primary_location":{"id":"doi:10.14529/food240210","doi":"https://doi.org/10.14529/food240210","is_oa":true,"landing_page_url":"https://doi.org/10.14529/food240210","pdf_url":"https://vestnik.susu.ru/food/article/download/14319/10658","source":{"id":"https://openalex.org/S4210169367","display_name":"Bulletin of the South Ural State University Series Food and Biotechnology","issn_l":"2310-2748","issn":["2310-2748","2413-0559"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I107640659","host_organization_name":"South Ural State University","host_organization_lineage":["https://openalex.org/I107640659"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the South Ural State University Series Food and Biotechnology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://vestnik.susu.ru/food/article/download/14319/10658","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5099987886","display_name":"Darya Chekushkina","orcid":"https://orcid.org/0009-0002-3826-8048","observed_orcids":["https://orcid.org/0009-0002-3826-8048"]},"institutions":[{"id":"https://openalex.org/I52135307","display_name":"Kemerovo State University","ror":"https://ror.org/036yvre49","country_code":"RU","type":"education","lineage":["https://openalex.org/I52135307"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Darya Chekushkina","raw_affiliation_strings":["Kemerovo State University , Kemerovo , Russia"],"raw_orcid":"https://orcid.org/0009-0002-3826-8048","affiliations":[{"raw_affiliation_string":"Kemerovo State University , Kemerovo , Russia","institution_ids":["https://openalex.org/I52135307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086982728","display_name":"Irina Milentyeva","orcid":"https://orcid.org/0000-0002-3536-562X","observed_orcids":["https://orcid.org/0000-0002-3536-562X"]},"institutions":[{"id":"https://openalex.org/I52135307","display_name":"Kemerovo State University","ror":"https://ror.org/036yvre49","country_code":"RU","type":"education","lineage":["https://openalex.org/I52135307"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Irina Milentyeva","raw_affiliation_strings":["Kemerovo State University , Kemerovo , Russia"],"raw_orcid":"https://orcid.org/0000-0002-3536-562X","affiliations":[{"raw_affiliation_string":"Kemerovo State University , Kemerovo , Russia","institution_ids":["https://openalex.org/I52135307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025246011","display_name":"Violeta Le","orcid":"https://orcid.org/0000-0002-9546-6633","observed_orcids":["https://orcid.org/0000-0002-9546-6633"]},"institutions":[{"id":"https://openalex.org/I52135307","display_name":"Kemerovo State University","ror":"https://ror.org/036yvre49","country_code":"RU","type":"education","lineage":["https://openalex.org/I52135307"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Violeta Le","raw_affiliation_strings":["Kemerovo State University , Kemerovo , Russia"],"raw_orcid":"https://orcid.org/0000-0002-9546-6633","affiliations":[{"raw_affiliation_string":"Kemerovo State University , Kemerovo , Russia","institution_ids":["https://openalex.org/I52135307"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056423897","display_name":"Alexander Yu. Prosekov","orcid":"https://orcid.org/0000-0002-5630-3196","observed_orcids":["https://orcid.org/0000-0002-5630-3196"]},"institutions":[{"id":"https://openalex.org/I52135307","display_name":"Kemerovo State University","ror":"https://ror.org/036yvre49","country_code":"RU","type":"education","lineage":["https://openalex.org/I52135307"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexander Prosekov","raw_affiliation_strings":["Kemerovo State University , Kemerovo , Russia"],"raw_orcid":"https://orcid.org/0000-0002-5630-3196","affiliations":[{"raw_affiliation_string":"Kemerovo State University , Kemerovo , Russia","institution_ids":["https://openalex.org/I52135307"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109532699","display_name":"Larisa A. Proskuryakova","orcid":"https://orcid.org/0000-0002-9583-9161","observed_orcids":["https://orcid.org/0000-0002-9583-9161"]},"institutions":[{"id":"https://openalex.org/I52135307","display_name":"Kemerovo State University","ror":"https://ror.org/036yvre49","country_code":"RU","type":"education","lineage":["https://openalex.org/I52135307"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Larisa Proskuryakova","raw_affiliation_strings":["Kemerovo State University , Kemerovo , Russia"],"raw_orcid":"https://orcid.org/0000-0002-9583-9161","affiliations":[{"raw_affiliation_string":"Kemerovo State University , Kemerovo , Russia","institution_ids":["https://openalex.org/I52135307"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I52135307"],"apc_list":null,"apc_paid":null,"fwci":1.0296,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.70800097,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":97},"biblio":{"volume":"12","issue":"2","first_page":"87","last_page":"95"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research","score":0.8895999789237976,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":0.04149999842047691,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trans-cinnamic-acid","display_name":"trans-cinnamic acid","score":1.0},{"id":"https://openalex.org/keywords/scutellaria-baicalensis","display_name":"Scutellaria baicalensis","score":0.9570000171661377},{"id":"https://openalex.org/keywords/biopotentials","display_name":"biopotentials","score":0.8840000033378601},{"id":"https://openalex.org/keywords/biosafety","display_name":"biosafety","score":0.9789999723434448},{"id":"https://openalex.org/keywords/antimutagenic-activity","display_name":"antimutagenic activity","score":0.8880000114440918},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8169999718666077},{"id":"https://openalex.org/keywords/hypocholesterolemic-activity","display_name":"hypocholesterolemic activity","score":0.8820000290870667},{"id":"https://openalex.org/keywords/hepatotoxicity","display_name":"hepatotoxicity","score":1.0},{"id":"https://openalex.org/keywords/proinflammatory-effects","display_name":"pro-inflammatory effects","score":0.906000018119812},{"id":"https://openalex.org/keywords/acute-inflammation","display_name":"acute inflammation","score":0.7549999952316284},{"id":"https://openalex.org/keywords/natural-organic-compounds","display_name":"natural organic compounds","score":0.4480000138282776}],"concepts":[{"id":"https://openalex.org/C2778831176","wikidata":"https://www.wikidata.org/wiki/Q164785","display_name":"Cinnamic acid","level":2,"score":0.7741159200668335},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5213974118232727},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3463500142097473},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2303352952003479}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.14529/food240210","doi":"https://doi.org/10.14529/food240210","is_oa":true,"landing_page_url":"https://doi.org/10.14529/food240210","pdf_url":"https://vestnik.susu.ru/food/article/download/14319/10658","source":{"id":"https://openalex.org/S4210169367","display_name":"Bulletin of the South Ural State University Series Food and Biotechnology","issn_l":"2310-2748","issn":["2310-2748","2413-0559"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I107640659","host_organization_name":"South Ural State University","host_organization_lineage":["https://openalex.org/I107640659"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the South Ural State University Series Food and Biotechnology","raw_type":"journal-article"},{"id":"pmh:oai:ojs.vestnik.susu.ac.ru:article/14319","doi":null,"is_oa":true,"landing_page_url":"https://vestnik.susu.ru/food/article/view/14319","pdf_url":null,"source":{"id":"https://openalex.org/S4210169367","display_name":"Bulletin of the South Ural State University Series Food and Biotechnology","issn_l":"2310-2748","issn":["2310-2748","2413-0559"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I107640659","host_organization_name":"South Ural State University","host_organization_lineage":["https://openalex.org/I107640659"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2310-2748","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:oai:dspace.susu.ru:0001.74/1234:00001.74/62858","doi":null,"is_oa":false,"landing_page_url":"http://dspace.susu.ru/xmlui/handle/00001.74/62858","pdf_url":null,"source":{"id":"https://openalex.org/S4306400771","display_name":"\u042d\u043b\u0435\u043a\u0442\u0440\u043e\u043d\u043d\u044b\u0439 \u0430\u0440\u0445\u0438\u0432 \u042e\u0423\u0440\u0413\u0423 (South Ural State University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I107640659","host_organization_name":"South Ural State University","host_organization_lineage":["https://openalex.org/I107640659"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.14529/food240210","doi":"https://doi.org/10.14529/food240210","is_oa":true,"landing_page_url":"https://doi.org/10.14529/food240210","pdf_url":"https://vestnik.susu.ru/food/article/download/14319/10658","source":{"id":"https://openalex.org/S4210169367","display_name":"Bulletin of the South Ural State University Series Food and Biotechnology","issn_l":"2310-2748","issn":["2310-2748","2413-0559"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I107640659","host_organization_name":"South Ural State University","host_organization_lineage":["https://openalex.org/I107640659"],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the South Ural State University Series Food and Biotechnology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4407899223.pdf","grobid_xml":"https://content.openalex.org/works/W4407899223.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4223526432","https://openalex.org/W4394563896","https://openalex.org/W2007868542","https://openalex.org/W2297751328","https://openalex.org/W1965911772","https://openalex.org/W3131729983","https://openalex.org/W2094073508","https://openalex.org/W1905446718","https://openalex.org/W7099574909","https://openalex.org/W2117131554"],"abstract_inverted_index":{"Trans-cinnamic":[0],"acid":[1,49],"(TKR-k)":[2],"is":[3,9,238],"a":[4,136,151,182,239,257],"natural":[5],"organic":[6],"compound":[7],"that":[8,141,232,245],"used":[10,108],"in":[11,69,86,103,164,185,212,234],"the":[12,38,43,52,56,70,81,91,94,97,165,196,209,222,249],"synthesis":[13],"of":[14,37,47,55,72,80,96,153,168,198,218,251,260],"various":[15],"chemical":[16],"and":[17,32,45,148,177,254],"pharmaceutical":[18],"preparations,":[19],"biologically":[20],"active":[21],"additives":[22],"(dietary":[23],"supplements).":[24],"It":[25,228],"has":[26,229],"high":[27],"biological":[28],"activity,":[29],"including":[30],"antioxidant":[31],"antibacterial":[33],"abilities.":[34],"The":[35,78],"aim":[36],"work":[39],"was":[40,83,139],"to":[41],"study":[42,82],"biopotential":[44],"biosafety":[46],"trans-cinnamic":[48],"isolated":[50,85],"from":[51,93],"cellular":[53],"biomass":[54,95],"Baikal":[57,98],"skullcap":[58,99],"(Scutellaria":[59,100],"baicalensis)":[60],"using":[61],"model":[62,110],"rodent":[63],"objects":[64],"for":[65],"its":[66],"further":[67],"application":[68],"development":[71,250],"dietary":[73,261],"supplements":[74,262],"with":[75,263],"geroprotective":[76,264],"activity.":[77],"object":[79],"TKR-k,":[84],"previously":[87],"conducted":[88],"studies":[89],"by":[90,189,201,216],"authors":[92],"baicalensis).":[101],"For":[102],"vivo":[104,235],"studies,":[105],"rodents":[106,237],"were":[107],"as":[109],"objects:":[111],"female":[112,129],"rats":[113,119,123],"(Rattus":[114],"sp.)":[115],"Sprague":[116],"Dawley,":[117],"male":[118,122,125],"Rattus":[120],"sp.,":[121],"Wistar,":[124],"mice":[126,130],"Mus":[127],"musculus,":[128],"(Mus":[131],"musculus)":[132],"stock":[133],"CD-1.":[134],"As":[135],"result,":[137],"it":[138,156,192],"established":[140,231],"TKR-k":[142,171,180,233],"did":[143,160,172],"not":[144,161,173,247],"have":[145,174],"mutagenic":[146],"properties,":[147],"when":[149],"administered":[150],"dose":[152],"50.0":[154],"mg/kg,":[155],"exhibited":[157,181],"antimutagenic":[158,243],"potential;":[159],"exhibit":[162],"cytotoxicity":[163],"concentration":[166],"range":[167],"2.1\u201333.3":[169],"\u03bcg/ml.":[170],"hypocholesterolemic":[175,252],"activity":[176,253],"hepatotoxicity.":[178],"However,":[179],"pro-inflammatory":[183],"effect":[184,207],"acute":[186],"inflammation":[187,214],"(caused":[188],"\u03bb-carrageenan)":[190],"\u2013":[191],"statistically":[193],"signifi-cantly":[194],"reduced":[195],"mass":[197],"granulation":[199],"tissue":[200],"20":[202],"%,":[203],"but":[204],"had":[205],"no":[206],"on":[208,226,236],"exudative":[210],"reaction":[211],"proliferative":[213],"caused":[215],"implantation":[217],"cotton":[219],"swabs":[220],"under":[221],"skin.":[223],"I":[224],"chew":[225],"rats.":[227],"been":[230],"bio-safe":[240],"substance":[241],"exhibiting":[242],"potential":[244],"does":[246],"stimulate":[248],"hepatotoxicity,":[255],"therefore,":[256],"promising":[258],"component":[259],"potential.":[265]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2025-02-25T00:00:00"}