{"id":"https://openalex.org/W4407889643","doi":"https://doi.org/10.1530/endoabs.109.oc6.5","title":"iPSC-derived hepatocytes offer a novel platform for modelling metabolic dysfunction-associated steatotic liver disease (MASLD) in vitro","display_name":"iPSC-derived hepatocytes offer a novel platform for modelling metabolic dysfunction-associated steatotic liver disease (MASLD) in vitro","publication_year":2025,"publication_date":"2025-02-19","ids":{"openalex":"https://openalex.org/W4407889643","doi":"https://doi.org/10.1530/endoabs.109.oc6.5"},"language":"en","primary_location":{"id":"doi:10.1530/endoabs.109.oc6.5","doi":"https://doi.org/10.1530/endoabs.109.oc6.5","is_oa":false,"landing_page_url":"https://doi.org/10.1530/endoabs.109.oc6.5","pdf_url":null,"source":{"id":"https://openalex.org/S4306509401","display_name":"Endocrine Abstracts","issn_l":"1470-3947","issn":["1470-3947","1479-6848","2046-0368"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrine Abstracts","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Magdalena Lukasiak","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Magdalena Lukasiak","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Samuel Chung","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samuel Chung","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5099059404","display_name":"George Kiloh","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George Kiloh","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111223985","display_name":"Gemma Gatti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gemma Gatti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059631681","display_name":"Chloe Robinson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chloe Robinson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059672948","display_name":"Ioannis Kasioulis","orcid":"https://orcid.org/0000-0001-5054-5357","observed_orcids":["https://orcid.org/0000-0001-5054-5357"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ioannis Kasioulis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5101927643","display_name":"Nikolaos Nikolaou","orcid":"https://orcid.org/0000-0002-8789-8436","observed_orcids":["https://orcid.org/0000-0002-8789-8436"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nikolaos Nikolaou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.018400000408291817,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ipsc-derived-hepatocytes","display_name":"iPSC-derived hepatocytes","score":0.871999979019165},{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":0.9679999947547913},{"id":"https://openalex.org/keywords/in-vitro-disease-model","display_name":"in vitro disease model","score":0.9369999766349792},{"id":"https://openalex.org/keywords/hepatocyte-differentiation","display_name":"hepatocyte differentiation","score":0.5569999814033508},{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.7279999852180481}],"concepts":[{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.6337977051734924},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.4757026135921478},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4551640748977661},{"id":"https://openalex.org/C2777075537","wikidata":"https://www.wikidata.org/wiki/Q929737","display_name":"Liver disease","level":2,"score":0.4414079785346985},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.42955484986305237},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3539636433124542},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3491332530975342},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.34046655893325806},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3313722014427185},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32230430841445923},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.276520699262619},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26102304458618164}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1530/endoabs.109.oc6.5","doi":"https://doi.org/10.1530/endoabs.109.oc6.5","is_oa":false,"landing_page_url":"https://doi.org/10.1530/endoabs.109.oc6.5","pdf_url":null,"source":{"id":"https://openalex.org/S4306509401","display_name":"Endocrine Abstracts","issn_l":"1470-3947","issn":["1470-3947","1479-6848","2046-0368"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319937","host_organization_name":"Bioscientifica","host_organization_lineage":["https://openalex.org/P4310319937"],"host_organization_lineage_names":["Bioscientifica"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Endocrine Abstracts","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4399536707","https://openalex.org/W4410019358","https://openalex.org/W7133284418","https://openalex.org/W7213484161","https://openalex.org/W7164857195","https://openalex.org/W7118309044","https://openalex.org/W4413851912","https://openalex.org/W4410050174","https://openalex.org/W7161566591","https://openalex.org/W4400381540"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2025-02-25T00:00:00"}