{"id":"https://openalex.org/W4409484767","doi":"https://doi.org/10.1021/jacs.5c03007","title":"Hexafluoroisopropanol Solvent Effects on Enantioselectivity of Dirhodium Tetracarboxylate-Catalyzed Cyclopropanation","display_name":"Hexafluoroisopropanol Solvent Effects on Enantioselectivity of Dirhodium Tetracarboxylate-Catalyzed Cyclopropanation","publication_year":2025,"publication_date":"2025-04-16","ids":{"openalex":"https://openalex.org/W4409484767","doi":"https://doi.org/10.1021/jacs.5c03007","pmid":"https://pubmed.ncbi.nlm.nih.gov/40237542","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12046558"},"language":"en","primary_location":{"id":"doi:10.1021/jacs.5c03007","doi":"https://doi.org/10.1021/jacs.5c03007","is_oa":true,"landing_page_url":"https://doi.org/10.1021/jacs.5c03007","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/jacs.5c03007","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015841445","display_name":"Turki M. Alturaifi","orcid":"https://orcid.org/0000-0002-6379-1669","observed_orcids":["https://orcid.org/0000-0002-6379-1669"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Turki M. Alturaifi","raw_affiliation_strings":["Department of Chemistry","University of Pittsburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004252421","display_name":"Kristin Shimabukuro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristin Shimabukuro","raw_affiliation_strings":["Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013658392","display_name":"Jack C. Sharland","orcid":"https://orcid.org/0000-0003-0895-6659","observed_orcids":["https://orcid.org/0000-0003-0895-6659"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jack C. Sharland","raw_affiliation_strings":["Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087735042","display_name":"Binh Khanh Mai","orcid":"https://orcid.org/0000-0001-8487-1417","observed_orcids":["https://orcid.org/0000-0001-8487-1417"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Binh Khanh Mai","raw_affiliation_strings":["Department of Chemistry","University of Pittsburgh"],"raw_orcid":"https://orcid.org/0000-0001-8487-1417","affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116342265","display_name":"Evan A. Weingarten","orcid":"https://orcid.org/0009-0006-7419-1577","observed_orcids":["https://orcid.org/0009-0006-7419-1577"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan A. Weingarten","raw_affiliation_strings":["Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072033343","display_name":"Mithun C. Madhusudhanan","orcid":"https://orcid.org/0000-0002-3122-0802","observed_orcids":["https://orcid.org/0000-0002-3122-0802"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mithun C. Madhusudhanan","raw_affiliation_strings":["Department of Chemistry","University of Pittsburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012743614","display_name":"Djamaladdin G. Musaev","orcid":"https://orcid.org/0000-0003-1160-6131","observed_orcids":["https://orcid.org/0000-0003-1160-6131"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Djamaladdin G. Musaev","raw_affiliation_strings":["Cherry L. Emerson Center for Scientific Computation, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States","Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States"],"raw_orcid":"https://orcid.org/0000-0003-1160-6131","affiliations":[{"raw_affiliation_string":"Cherry L. Emerson Center for Scientific Computation, Emory University, 1521 Dickey Drive, Atlanta, Georgia 30322, United States","institution_ids":["https://openalex.org/I150468666"]},{"raw_affiliation_string":"Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021833788","display_name":"Peng Liu","orcid":"https://orcid.org/0000-0002-8188-632X","observed_orcids":["https://orcid.org/0000-0002-8188-632X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peng Liu","raw_affiliation_strings":["Department of Chemistry","University of Pittsburgh"],"raw_orcid":"https://orcid.org/0000-0002-8188-632X","affiliations":[{"raw_affiliation_string":"Department of Chemistry","institution_ids":[]},{"raw_affiliation_string":"University of Pittsburgh","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083948798","display_name":"Huw M. L. Davies","orcid":"https://orcid.org/0000-0001-6254-9398","observed_orcids":["https://orcid.org/0000-0001-6254-9398"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Huw M. L. Davies","raw_affiliation_strings":["Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States"],"raw_orcid":"https://orcid.org/0000-0001-6254-9398","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States","institution_ids":["https://openalex.org/I150468666"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012743614","https://openalex.org/A5021833788","https://openalex.org/A5083948798"],"corresponding_institution_ids":["https://openalex.org/I150468666","https://openalex.org/I170201317"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":{"value":4500,"currency":"USD","value_usd":4500},"fwci":4.5252,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.96266724,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"147","issue":"17","first_page":"14694","last_page":"14704"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11611","display_name":"Cyclopropane Reaction Mechanisms","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11611","display_name":"Cyclopropane Reaction Mechanisms","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10092","display_name":"Organometallic Complex Synthesis and Catalysis","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hexafluoroisopropanol","display_name":"hexafluoroisopropanol","score":0.9890000224113464},{"id":"https://openalex.org/keywords/solvent-effects","display_name":"solvent effects","score":0.8650000095367432},{"id":"https://openalex.org/keywords/enantioselectivity","display_name":"enantioselectivity","score":0.9620000123977661},{"id":"https://openalex.org/keywords/cyclopropanation","display_name":"cyclopropanation","score":0.9120000004768372},{"id":"https://openalex.org/keywords/aryldiazoacetates","display_name":"aryldiazoacetates","score":0.9779999852180481},{"id":"https://openalex.org/keywords/chiral-catalysts","display_name":"chiral catalysts","score":0.578000009059906},{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.746999979019165}],"concepts":[{"id":"https://openalex.org/C2777052750","wikidata":"https://www.wikidata.org/wiki/Q17156600","display_name":"Cyclopropanation","level":3,"score":0.980309247970581},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.980178713798523},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.6693633794784546},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.6296216249465942},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.3901635706424713},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.35857897996902466}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1021/jacs.5c03007","doi":"https://doi.org/10.1021/jacs.5c03007","is_oa":true,"landing_page_url":"https://doi.org/10.1021/jacs.5c03007","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},{"id":"doi:10.26434/chemrxiv-2025-mlb1q","doi":"https://doi.org/10.26434/chemrxiv-2025-mlb1q","is_oa":true,"landing_page_url":"https://doi.org/10.26434/chemrxiv-2025-mlb1q","pdf_url":null,"source":{"id":"https://openalex.org/S4393918830","display_name":"ChemRxiv","issn_l":"2573-2293","issn":["2573-2293"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:12046558","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12046558","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Chem Soc","raw_type":"Text"},{"id":"pmid:40237542","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40237542","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1021/jacs.5c03007","doi":"https://doi.org/10.1021/jacs.5c03007","is_oa":true,"landing_page_url":"https://doi.org/10.1021/jacs.5c03007","pdf_url":null,"source":{"id":"https://openalex.org/S111155417","display_name":"Journal of the American Chemical Society","issn_l":"0002-7863","issn":["0002-7863","1520-5126","1943-2984"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Chemical Society","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1207660340","display_name":null,"funder_award_id":"GM-099142","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2071680558","display_name":"New Directions in Enantioselective C-H Functionalization","funder_award_id":"R01GM099142","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2592393619","display_name":null,"funder_award_id":"SCR_022735","funder_id":"https://openalex.org/F4320333934","funder_display_name":"Center for Research Computing, University of Pittsburgh"},{"id":"https://openalex.org/G5260668849","display_name":"Category I. Computing without Boundaries: Cyberinfrastructure for the Long Tail of Science","funder_award_id":"1928224","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G5593089889","display_name":"MRI: Acquisition of Cutting-Edge GPU and MPI Nodes for the Interdisciplinary Pitt Center for Research Computing","funder_award_id":"2117681","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G7332361580","display_name":"Category I: Bridges-2: Scalable Converged Computing, Data, and Analytics for Rapidly Evolving Science and Engineering Research","funder_award_id":"1928147","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G9000902904","display_name":"Computational Models for Reactivity and Selectivity in Catalytic Olefin Functionalization","funder_award_id":"R35GM128779","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333934","display_name":"Center for Research Computing, University of Pittsburgh","ror":null},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1969457598","https://openalex.org/W1988118827","https://openalex.org/W2003509354","https://openalex.org/W2024874069","https://openalex.org/W2033048991","https://openalex.org/W2042828902","https://openalex.org/W2085403158","https://openalex.org/W2147993766","https://openalex.org/W2153287991","https://openalex.org/W2275563446","https://openalex.org/W2296842302","https://openalex.org/W2495633209","https://openalex.org/W2510289573","https://openalex.org/W2529319041","https://openalex.org/W2605801743","https://openalex.org/W2768088257","https://openalex.org/W2776088498","https://openalex.org/W2783315058","https://openalex.org/W2803032584","https://openalex.org/W2898697279","https://openalex.org/W2905531315","https://openalex.org/W2944679719","https://openalex.org/W2951797189","https://openalex.org/W2963155797","https://openalex.org/W2971598464","https://openalex.org/W2996911249","https://openalex.org/W3013317464","https://openalex.org/W3016090652","https://openalex.org/W3042151941","https://openalex.org/W3080403564","https://openalex.org/W3082541940","https://openalex.org/W3127797438","https://openalex.org/W3186219953","https://openalex.org/W3216107856","https://openalex.org/W4200004323","https://openalex.org/W4206965283","https://openalex.org/W4220929903","https://openalex.org/W4285677181","https://openalex.org/W4294308654","https://openalex.org/W4295359832","https://openalex.org/W4298122573","https://openalex.org/W4306746532","https://openalex.org/W4306822733","https://openalex.org/W4307566544","https://openalex.org/W4312110894","https://openalex.org/W4321375658","https://openalex.org/W4381327183","https://openalex.org/W4387041696","https://openalex.org/W4392286269","https://openalex.org/W4394857084","https://openalex.org/W4400046084"],"related_works":["https://openalex.org/W4407773263","https://openalex.org/W4298122573","https://openalex.org/W2949186321","https://openalex.org/W2047910753","https://openalex.org/W2950834346","https://openalex.org/W2333507101","https://openalex.org/W1985365146","https://openalex.org/W2011453525","https://openalex.org/W2327812706","https://openalex.org/W2949983654"],"abstract_inverted_index":{"High":[0],"Resolution":[1],"Image":[2],"Download":[3],"MS":[4],"PowerPoint":[5],"Slide":[6],"In":[7],"recent":[8],"years,":[9],"additives":[10],"that":[11,97],"modulate":[12],"both":[13],"reactivity":[14,39],"and":[15,40,71,89],"selectivity":[16],"in":[17,47,117,123,143,145,159],"rhodium-catalyzed":[18],"reactions":[19,65],"of":[20,50,63,78,125,137],"aryldiazoacetates":[21],"have":[22,32,105,140],"become":[23],"increasingly":[24],"prominent.":[25],"1,1,1,3,3,3-Hexafluoroisopropanol":[26],"(HFIP)":[27],"has":[28,56],"been":[29,106],"shown":[30],"to":[31,109,156,170],"a":[33,57,135,141,157,171],"profound":[34],"effect":[35],"on":[36,43,60],"rhodium":[37,80],"carbene":[38,45],"selectivity,":[41],"especially":[42],"enabling":[44],"cyclopropanation":[46],"the":[48,61,64,75,79,98,126,138],"presence":[49],"various":[51],"nucleophilic":[52],"poisons.":[53],"HFIP":[54],"also":[55],"variable":[58],"influence":[59],"enantioselectivity":[62,144],"catalyzed":[66],"by":[67],"chiral":[68],"dirhodium":[69],"tetracarboxylates,":[70],"this":[72,118],"study":[73],"examines":[74],"fundamental":[76],"properties":[77],"carbene/HFIP":[81],"system":[82],"through":[83],"experimentation,":[84],"density":[85],"functional":[86],"theory":[87],"(DFT),":[88],"molecular":[90],"dynamics":[91],"(MD)":[92],"simulations.":[93],"These":[94,129],"studies":[95,130],"revealed":[96],"C":[99],"4":[100],"-symmetric":[101],"bowl-shaped":[102,127],"catalysts,":[103,148],"which":[104],"previously":[107],"considered":[108],"be":[110],"relatively":[111],"rigid,":[112],"experience":[113],"far":[114],"greater":[115],"flexibility":[116],"hydrogen":[119],"bonding":[120],"media,":[121],"resulting":[122],"distortion":[124],"catalysts.":[128],"explain":[131],"why":[132],"even":[133],"though":[134],"majority":[136],"catalysts":[139],"drop":[142],"HFIP,":[146],"some":[147],"such":[149,163],"as":[150,164],"Rh":[151,165],"2":[152,166],"(TCPTAD)":[153],"4,":[154,168],"lead":[155,169],"switch":[158],"enantioselectivity,":[160],"whereas":[161],"others,":[162],"(NTTL)":[167],"considerably":[172],"enhanced":[173],"enantioselectivity.":[174]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2025-04-16T00:00:00"}
