{"id":"https://openalex.org/W4407667232","doi":"https://doi.org/10.1158/1078-0432.28428219","title":"Supplementary Table 2 from A Phase I Study of FHD-609, a Heterobifunctional Degrader of Bromodomain-Containing Protein 9, in Patients with Advanced Synovial Sarcoma or SMARCB1-Deficient Tumors","display_name":"Supplementary Table 2 from A Phase I Study of FHD-609, a Heterobifunctional Degrader of Bromodomain-Containing Protein 9, in Patients with Advanced Synovial Sarcoma or SMARCB1-Deficient Tumors","publication_year":2025,"publication_date":"2025-02-17","ids":{"openalex":"https://openalex.org/W4407667232","doi":"https://doi.org/10.1158/1078-0432.28428219"},"language":"en","primary_location":{"id":"doi:10.1158/1078-0432.28428219","doi":"https://doi.org/10.1158/1078-0432.28428219","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.28428219","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Table_2_from_A_Phase_I_Study_of_FHD-609_a_Heterobifunctional_Degrader_of_Bromodomain-Containing_Protein_9_in_Patients_with_Advanced_Synovial_Sarcoma_or_SMARCB1-Deficient_Tumors/28428219/1/files/52399566.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"volume":null,"type":"supplementary-materials","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Table_2_from_A_Phase_I_Study_of_FHD-609_a_Heterobifunctional_Degrader_of_Bromodomain-Containing_Protein_9_in_Patients_with_Advanced_Synovial_Sarcoma_or_SMARCB1-Deficient_Tumors/28428219/1/files/52399566.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5086656974","display_name":"John Andrew Livingston","orcid":"https://orcid.org/0000-0002-1337-3282","observed_orcids":["https://orcid.org/0000-0002-1337-3282"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. Andrew Livingston","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1337-3282","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042202815","display_name":"Jean\u2010Yves Blay","orcid":"https://orcid.org/0000-0001-7190-120X","observed_orcids":["https://orcid.org/0000-0001-7190-120X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jean-Yves Blay","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-7190-120X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004418792","display_name":"Jonathan C. Trent","orcid":"https://orcid.org/0000-0001-6169-5238","observed_orcids":["https://orcid.org/0000-0001-6169-5238"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jonathan Trent","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6169-5238","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009531132","display_name":"Claudia Mar\u00eda Valverde","orcid":"https://orcid.org/0000-0003-4107-8616","observed_orcids":["https://orcid.org/0000-0003-4107-8616"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claudia Valverde","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4107-8616","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031405616","display_name":"Mark Agulnik","orcid":"https://orcid.org/0000-0003-3513-3519","observed_orcids":["https://orcid.org/0000-0003-3513-3519"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Agulnik","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-3513-3519","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034595315","display_name":"Mrinal M. Gounder","orcid":"https://orcid.org/0000-0001-8468-0119","observed_orcids":["https://orcid.org/0000-0001-8468-0119"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mrinal Gounder","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-8468-0119","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090103193","display_name":"Axel Le Cesne","orcid":"https://orcid.org/0000-0002-8006-8659","observed_orcids":["https://orcid.org/0000-0002-8006-8659"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Axel Le Cesne","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8006-8659","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002575629","display_name":"Meredith Ann McKean","orcid":"https://orcid.org/0000-0003-0944-7418","observed_orcids":["https://orcid.org/0000-0003-0944-7418"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Meredith McKean","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0944-7418","affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Michael J. Wagner","orcid":"https://orcid.org/0000-0002-0753-9282","observed_orcids":["https://orcid.org/0000-0002-0753-9282"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael J. Wagner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-0753-9282","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060954086","display_name":"Silvia Stacchiotti","orcid":"https://orcid.org/0000-0002-1742-8666","observed_orcids":["https://orcid.org/0000-0002-1742-8666"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Silvia Stacchiotti","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1742-8666","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108267512","display_name":"Samuel V. Agresta","orcid":"https://orcid.org/0009-0000-5795-8234","observed_orcids":["https://orcid.org/0009-0000-5795-8234"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samuel Agresta","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0000-5795-8234","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107977581","display_name":"Alfonso Quint\u00e1s\u2010Cardama","orcid":"https://orcid.org/0000-0002-4623-8917","observed_orcids":["https://orcid.org/0000-0002-4623-8917"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alfonso Quint\u00e1s-Cardama","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4623-8917","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113042998","display_name":"Sarah A. Reilly","orcid":"https://orcid.org/0009-0005-4696-6120","observed_orcids":["https://orcid.org/0009-0005-4696-6120"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sarah A. Reilly","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0005-4696-6120","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112002821","display_name":"Kathleen Healy","orcid":"https://orcid.org/0009-0002-4038-6270","observed_orcids":["https://orcid.org/0009-0002-4038-6270"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathleen Healy","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-4038-6270","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110610157","display_name":"Denice Kaylor Hickman","orcid":"https://orcid.org/0009-0007-1812-7092","observed_orcids":["https://orcid.org/0009-0007-1812-7092"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Denice Hickman","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0007-1812-7092","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111072886","display_name":"Tina Zhao","orcid":"https://orcid.org/0009-0008-0114-191X","observed_orcids":["https://orcid.org/0009-0008-0114-191X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tina Zhao","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0008-0114-191X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087083271","display_name":"Alex Ballesteros\u2010Perez","orcid":"https://orcid.org/0009-0002-8047-7185","observed_orcids":["https://orcid.org/0009-0002-8047-7185"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alex Ballesteros-Perez","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0002-8047-7185","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109477793","display_name":"Alexis Khalil","orcid":"https://orcid.org/0009-0008-9231-7641","observed_orcids":["https://orcid.org/0009-0008-9231-7641"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexis Khalil","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0008-9231-7641","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009275057","display_name":"Michael P. Collins","orcid":"https://orcid.org/0000-0002-1806-6775","observed_orcids":["https://orcid.org/0000-0002-1806-6775"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael P. Collins","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1806-6775","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084422325","display_name":"Jessica C. Piel","orcid":"https://orcid.org/0009-0003-8299-5370","observed_orcids":["https://orcid.org/0009-0003-8299-5370"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jessica Piel","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0003-8299-5370","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001848151","display_name":"Kim Horrigan","orcid":"https://orcid.org/0009-0009-9724-6499","observed_orcids":["https://orcid.org/0009-0009-9724-6499"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kim Horrigan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0009-9724-6499","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021228211","display_name":"Ariel J. Lefkovith","orcid":"https://orcid.org/0000-0003-4519-0429","observed_orcids":["https://orcid.org/0000-0003-4519-0429"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ariel Lefkovith","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-4519-0429","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081227757","display_name":"Scott Innis","orcid":"https://orcid.org/0009-0000-2195-424X","observed_orcids":["https://orcid.org/0009-0000-2195-424X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott Innis","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0009-0000-2195-424X","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050445982","display_name":"Alexander J. Lazar","orcid":"https://orcid.org/0000-0002-6395-4499","observed_orcids":["https://orcid.org/0000-0002-6395-4499"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alexander J. Lazar","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-6395-4499","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105923745","display_name":"Gregory Michael Cote","orcid":"https://orcid.org/0000-0003-0181-886X","observed_orcids":["https://orcid.org/0000-0003-0181-886X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gregory M. Cote","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0003-0181-886X","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5002989987","display_name":"Andrew J. Wagner","orcid":"https://orcid.org/0000-0002-4384-9448","observed_orcids":["https://orcid.org/0000-0002-4384-9448"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew J. Wagner","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-4384-9448","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12534","display_name":"Protein Degradation and Inhibitors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12534","display_name":"Protein Degradation and Inhibitors","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bcl11a","display_name":"BCL11A","score":0.7250000238418579},{"id":"https://openalex.org/keywords/heterobifunctional-degraders","display_name":"heterobifunctional degraders","score":0.9419999718666077},{"id":"https://openalex.org/keywords/synovial-sarcoma","display_name":"synovial sarcoma","score":0.7799999713897705},{"id":"https://openalex.org/keywords/smarcb1-deficiency","display_name":"SMARCB1 deficiency","score":0.9269999861717224}],"concepts":[{"id":"https://openalex.org/C2776910622","wikidata":"https://www.wikidata.org/wiki/Q2619315","display_name":"Synovial sarcoma","level":3,"score":0.7823785543441772},{"id":"https://openalex.org/C74401373","wikidata":"https://www.wikidata.org/wiki/Q1829843","display_name":"Bromodomain","level":4,"score":0.6615943312644958},{"id":"https://openalex.org/C177450382","wikidata":"https://www.wikidata.org/wiki/Q18031596","display_name":"SMARCB1","level":5,"score":0.5729238986968994},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5727129578590393},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.46561741828918457},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4610231816768646},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.40863391757011414},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.40725696086883545},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.18351617455482483},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12713801860809326},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09687232971191406},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.09224170446395874},{"id":"https://openalex.org/C167227067","wikidata":"https://www.wikidata.org/wiki/Q5113739","display_name":"Chromatin remodeling","level":4,"score":0.0},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.0},{"id":"https://openalex.org/C64927066","wikidata":"https://www.wikidata.org/wiki/Q36293","display_name":"Histone","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1158/1078-0432.28428219","doi":"https://doi.org/10.1158/1078-0432.28428219","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.28428219","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Table_2_from_A_Phase_I_Study_of_FHD-609_a_Heterobifunctional_Degrader_of_Bromodomain-Containing_Protein_9_in_Patients_with_Advanced_Synovial_Sarcoma_or_SMARCB1-Deficient_Tumors/28428219/1/files/52399566.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},{"id":"pmh:oai:figshare.com:article/28428219","doi":null,"is_oa":true,"landing_page_url":"https://figshare.com/articles/journal_contribution/Supplementary_Table_2_from_A_Phase_I_Study_of_FHD-609_a_Heterobifunctional_Degrader_of_Bromodomain-Containing_Protein_9_in_Patients_with_Advanced_Synovial_Sarcoma_or_SMARCB1-Deficient_Tumors/28428219","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1158/1078-0432.28428219","doi":"https://doi.org/10.1158/1078-0432.28428219","is_oa":true,"landing_page_url":"https://doi.org/10.1158/1078-0432.28428219","pdf_url":"https://aacr.figshare.com/articles/journal_contribution/Supplementary_Table_2_from_A_Phase_I_Study_of_FHD-609_a_Heterobifunctional_Degrader_of_Bromodomain-Containing_Protein_9_in_Patients_with_Advanced_Synovial_Sarcoma_or_SMARCB1-Deficient_Tumors/28428219/1/files/52399566.pdf","source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"American Association for Cancer Research","raw_type":"posted-content"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9476000070571899}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4407667232.pdf","grobid_xml":"https://content.openalex.org/works/W4407667232.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4407629304","https://openalex.org/W4405288624","https://openalex.org/W7172415724","https://openalex.org/W4282975861","https://openalex.org/W2900693695","https://openalex.org/W4389240441","https://openalex.org/W7213234000","https://openalex.org/W4416266643","https://openalex.org/W4391532492","https://openalex.org/W7204947013"],"abstract_inverted_index":{"SupplementaryTable":[0],"2:":[1],"Representativeness":[2],"of":[3],"study":[4],"participants.":[5]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2025-02-18T00:00:00"}