{"id":"https://openalex.org/W4407308947","doi":"https://doi.org/10.4103/injms.injms_39_24","title":"Triglyceride-glucose Index as a Novel Early Risk Predictor for Cardiovascular Disease in Type 2 Diabetes Mellitus Patients with Hypertension","display_name":"Triglyceride-glucose Index as a Novel Early Risk Predictor for Cardiovascular Disease in Type 2 Diabetes Mellitus Patients with Hypertension","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4407308947","doi":"https://doi.org/10.4103/injms.injms_39_24"},"language":"en","primary_location":{"id":"doi:10.4103/injms.injms_39_24","doi":"https://doi.org/10.4103/injms.injms_39_24","is_oa":true,"landing_page_url":"https://doi.org/10.4103/injms.injms_39_24","pdf_url":null,"source":{"id":"https://openalex.org/S2764616852","display_name":"Indian Journal of Medical Specialities","issn_l":"0976-2884","issn":["0976-2884","0976-2892"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-c","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Medical Specialities","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/injms.injms_39_24","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015812670","display_name":"Neelima Raj","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136170","display_name":"Government Medical College and Hospital","ror":"https://ror.org/04f6gef75","country_code":"IN","type":"other","lineage":["https://openalex.org/I4210136170"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Neelima Raj","raw_affiliation_strings":["Department of Biochemistry, Government Medical College and Hospital, Akola, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Government Medical College and Hospital, Akola, Maharashtra, India","institution_ids":["https://openalex.org/I4210136170"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112339527","display_name":"Kumud Namdeorao Harley","orcid":"https://orcid.org/0000-0001-7585-6784","observed_orcids":["https://orcid.org/0000-0001-7585-6784"]},"institutions":[{"id":"https://openalex.org/I4210136170","display_name":"Government Medical College and Hospital","ror":"https://ror.org/04f6gef75","country_code":"IN","type":"other","lineage":["https://openalex.org/I4210136170"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kumud N. Harley","raw_affiliation_strings":["Department of Biochemistry, Government Medical College and Hospital, Akola, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Government Medical College and Hospital, Akola, Maharashtra, India","institution_ids":["https://openalex.org/I4210136170"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065511862","display_name":"Prerna Nandedkar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136170","display_name":"Government Medical College and Hospital","ror":"https://ror.org/04f6gef75","country_code":"IN","type":"other","lineage":["https://openalex.org/I4210136170"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Prerna Nandedkar","raw_affiliation_strings":["Department of Biochemistry, Government Medical College and Hospital, Akola, Maharashtra, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Government Medical College and Hospital, Akola, Maharashtra, India","institution_ids":["https://openalex.org/I4210136170"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5015812670"],"corresponding_institution_ids":["https://openalex.org/I4210136170"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"16","issue":"1","first_page":"18","last_page":"21"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10560","display_name":"Diabetes Management and Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/triglyceride-glucose-index","display_name":"triglyceride-glucose index","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9259999990463257},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cardiovascular-risk-prediction","display_name":"cardiovascular risk prediction","score":0.9369999766349792},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9319999814033508},{"id":"https://openalex.org/keywords/cardiovascular-risk-markers","display_name":"cardiovascular risk markers","score":0.640999972820282},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.8019999861717224},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.6669999957084656},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.7459999918937683},{"id":"https://openalex.org/keywords/triglycerides","display_name":"triglycerides","score":0.6790000200271606},{"id":"https://openalex.org/keywords/cardiovascular-risk-screening","display_name":"cardiovascular risk screening","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9710352420806885},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6840069890022278},{"id":"https://openalex.org/C2778913445","wikidata":"https://www.wikidata.org/wiki/Q186319","display_name":"Triglyceride","level":3,"score":0.658392608165741},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.6535701155662537},{"id":"https://openalex.org/C2910068830","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 Diabetes Mellitus","level":3,"score":0.6518112421035767},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5556554198265076},{"id":"https://openalex.org/C2777382242","wikidata":"https://www.wikidata.org/wiki/Q6017816","display_name":"Index (typography)","level":2,"score":0.4800751805305481},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.45853811502456665},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.24002349376678467},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.20019477605819702},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.4103/injms.injms_39_24","doi":"https://doi.org/10.4103/injms.injms_39_24","is_oa":true,"landing_page_url":"https://doi.org/10.4103/injms.injms_39_24","pdf_url":null,"source":{"id":"https://openalex.org/S2764616852","display_name":"Indian Journal of Medical Specialities","issn_l":"0976-2884","issn":["0976-2884","0976-2892"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-c","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Medical Specialities","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:716fc4c4506f44dcb0fc609e2bef257f","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/716fc4c4506f44dcb0fc609e2bef257f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Indian Journal of Medical Specialities, Vol 16, Iss 1, Pp 18-21 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/injms.injms_39_24","doi":"https://doi.org/10.4103/injms.injms_39_24","is_oa":true,"landing_page_url":"https://doi.org/10.4103/injms.injms_39_24","pdf_url":null,"source":{"id":"https://openalex.org/S2764616852","display_name":"Indian Journal of Medical Specialities","issn_l":"0976-2884","issn":["0976-2884","0976-2892"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","dongbi-c","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Indian Journal of Medical Specialities","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1967999753","https://openalex.org/W1995388442","https://openalex.org/W2020267609","https://openalex.org/W2023531846","https://openalex.org/W2101508556","https://openalex.org/W3010747147","https://openalex.org/W4287701344","https://openalex.org/W4311575465","https://openalex.org/W4387701431","https://openalex.org/W6840223021"],"related_works":["https://openalex.org/W3215211794","https://openalex.org/W3208889448","https://openalex.org/W4406820298","https://openalex.org/W4415100452","https://openalex.org/W4389050499","https://openalex.org/W4379780668","https://openalex.org/W4385724188","https://openalex.org/W4407830430","https://openalex.org/W4391358220","https://openalex.org/W4416649473"],"abstract_inverted_index":{"Abstract":[0],"Background:":[1],"Type":[2],"2":[3],"diabetes":[4],"mellitus":[5],"(T2DM),":[6],"marked":[7],"by":[8,148],"insulin":[9],"resistance":[10],"or":[11],"deficiency,":[12],"and":[13,90,104,132,142,193,248,262],"hypertension":[14],"(HTN),":[15],"a":[16,39,80,85,166,265],"diabetic":[17,110],"risk":[18,45,57,251,287],"factor,":[19],"elevates":[20],"cardiovascular":[21,250],"disease":[22],"(CVD)":[23],"risk.":[24],"Traditional":[25],"lipid":[26,292],"profiles":[27],"may":[28],"be":[29],"inconclusive;":[30],"hence,":[31],"the":[32,91,143,149,163,204,212,224,245,274],"emerging":[33],"triglyceride-glucose":[34],"(TyG)":[35],"index":[36,51,145,206,247,276],"serves":[37],"as":[38,95,279],"feasible":[40],"biomarker":[41],"for":[42,211,223],"early":[43,55,281],"CVD":[44,56,286],"prediction.":[46],"This":[47,229],"study":[48,65,271],"assesses":[49],"TyG":[50,144,205,246,275],"utility":[52],"in":[53,84,288],"predicting":[54],"among":[58],"hypertensive":[59,102],"T2DM":[60,69],"patients.":[61],"Methodology:":[62],"An":[63],"observational":[64],"was":[66,140,146,207,219,231],"conducted":[67],"on":[68],"patients":[70],"(":[71],"n":[72],"=":[73,267],"100)":[74],"with":[75,98,101,107,174,214,234,264],"age":[76],">40":[77],"years,":[78],"attending":[79],"medical":[81],"outpatient":[82],"clinic":[83],"tertiary":[86],"health-care":[87],"center,":[88],"Akola,":[89],"subjects":[92],"were":[93,135,173,178,191,195,242],"categorized":[94],"Group":[96,105],"I":[97],"50":[99,108,188],"participants":[100,170,177],"DM":[103,213,225],"II":[106],"nonhypertensive":[109],"participants.":[111,197],"The":[112,198,270],"laboratory":[113],"investigations,":[114],"including":[115,253],"fasting":[116,156],"blood":[117,157,255],"sugar":[118],"(FBS),":[119],"triglycerides":[120],"(TG),":[121],"total":[122,167],"cholesterol":[123,130],"(TC),":[124],"high-density":[125],"lipoprotein":[126,129],"cholesterol,":[127],"low-density":[128],"(LDL-C),":[131],"very":[133],"LDL-C,":[134,263],"estimated.":[136],"Appropriate":[137],"statistical":[138],"analysis":[139],"applied":[141],"calculated":[147],"formula:":[150],"Ln":[151],"(fasting":[152],"TG":[153],"[mg/dL]":[154],"\u00d7":[155],"glucose":[158],"[mg/dL]/2)":[159],"3.":[160],"Results:":[161],"In":[162,183,238],"present":[164],"study,":[165],"of":[168,187,203],"100":[169],"examined":[171],"who":[172],"DM.":[175],"These":[176],"divided":[179],"into":[180],"two":[181],"groups.":[182],"both":[184],"groups,":[185],"out":[186],"participants,":[189],"25":[190,194],"male":[192],"female":[196],"mean":[199],"\u00b1":[200,209,221],"standard":[201],"deviation":[202],"5.08":[208],"0.10":[210],"HTN":[215,227],"group,":[216],"whereas":[217],"it":[218],"4.97":[220],"0.30":[222],"without":[226],"group.":[228],"difference":[230],"statistically":[232],"significant":[233,240],"P":[235,266],"<":[236],"0.0001.":[237,268],"addition,":[239],"associations":[241],"observed":[243],"between":[244],"various":[249],"factors,":[252],"systolic":[254],"pressure":[256],"(BP),":[257],"diastolic":[258],"BP,":[259],"FBS,":[260],"TG,":[261],"Conclusion:":[269],"concluded":[272],"that":[273],"might":[277],"serve":[278],"an":[280],"screening":[282],"tool":[283],"to":[284,290],"calculate":[285],"addition":[289],"routine":[291],"parameters.":[293]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2025-02-11T00:00:00"}