{"id":"https://openalex.org/W4407206933","doi":"https://doi.org/10.1039/d4fo05835f","title":"Bifidobacterium bifidum CCFM1163 alleviates cathartic colon by activating the BDNF-TrkB-PLC/IP 3 pathway to reconstruct the intestinal nerve and barrier","display_name":"Bifidobacterium bifidum CCFM1163 alleviates cathartic colon by activating the BDNF-TrkB-PLC/IP 3 pathway to reconstruct the intestinal nerve and barrier","publication_year":2025,"publication_date":"2025-01-01","ids":{"openalex":"https://openalex.org/W4407206933","doi":"https://doi.org/10.1039/d4fo05835f","pmid":"https://pubmed.ncbi.nlm.nih.gov/39963068"},"language":"en","primary_location":{"id":"doi:10.1039/d4fo05835f","doi":"https://doi.org/10.1039/d4fo05835f","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d4fo05835f","pdf_url":null,"source":{"id":"https://openalex.org/S2483688756","display_name":"Food & Function","issn_l":"2042-6496","issn":["2042-6496","2042-650X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food & Function","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027181514","display_name":"Shengnan Zhu","orcid":"https://orcid.org/0000-0003-0521-5978","observed_orcids":["https://orcid.org/0000-0003-0521-5978"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shengnan Zhu","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058424564","display_name":"Qiangqing Yu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiangqing Yu","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009277601","display_name":"Yifan Xue","orcid":"https://orcid.org/0000-0002-7818-0916","observed_orcids":["https://orcid.org/0000-0002-7818-0916"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yifan Xue","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014516371","display_name":"Jiazhen Li","orcid":"https://orcid.org/0009-0008-2531-7684","observed_orcids":["https://orcid.org/0009-0008-2531-7684","https://orcid.org/0000-0001-5996-4814"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiazhen Li","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030172482","display_name":"Yin Cheng Huang","orcid":"https://orcid.org/0000-0001-6913-4670","observed_orcids":["https://orcid.org/0000-0001-6913-4670"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yin Huang","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wenxu Liu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenxu Liu","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100367449","display_name":"Gang Wang","orcid":"https://orcid.org/0000-0003-2007-2143","observed_orcids":["https://orcid.org/0000-0003-2007-2143"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Gang Wang","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":"https://orcid.org/0000-0003-2007-2143","affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Linlin Wang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Linlin Wang","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035534812","display_name":"Qixiao Zhai","orcid":"https://orcid.org/0000-0002-0605-2675","observed_orcids":["https://orcid.org/0000-0002-0605-2675","https://orcid.org/0000-0001-6072-3540","https://orcid.org/0000-0003-1415-7247"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qixiao Zhai","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":"https://orcid.org/0000-0002-0605-2675","affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jianxin Zhao","orcid":"https://orcid.org/0000-0003-4516-0799","observed_orcids":["https://orcid.org/0000-0003-4516-0799"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianxin Zhao","raw_affiliation_strings":["School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":"https://orcid.org/0000-0003-4516-0799","affiliations":[{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113990871","display_name":"Hao Zhang","orcid":"https://orcid.org/0000-0002-9192-4684","observed_orcids":["https://orcid.org/0000-0002-9192-4684","https://orcid.org/0000-0003-3741-7494","https://orcid.org/0000-0003-0916-8371","https://orcid.org/0000-0002-3322-3070","https://orcid.org/0000-0002-5046-9785","https://orcid.org/0000-0002-1656-0091"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Zhang","raw_affiliation_strings":["(Yangzhou) Institute of Food Biotechnology, Jiangnan University, Yangzhou 225004, China","National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, China","School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(Yangzhou) Institute of Food Biotechnology, Jiangnan University, Yangzhou 225004, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]},{"author_position":"last","author":{"id":null,"display_name":"Wei Chen","orcid":"https://orcid.org/0000-0003-3348-4710","observed_orcids":["https://orcid.org/0000-0003-3348-4710"]},"institutions":[{"id":"https://openalex.org/I111599522","display_name":"Jiangnan University","ror":"https://ror.org/04mkzax54","country_code":"CN","type":"education","lineage":["https://openalex.org/I111599522"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Chen","raw_affiliation_strings":["National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, China","School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China"],"raw_orcid":"https://orcid.org/0000-0003-3348-4710","affiliations":[{"raw_affiliation_string":"National Engineering Research Center for Functional Food, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China","institution_ids":["https://openalex.org/I111599522"]},{"raw_affiliation_string":"State Key Laboratory of Food Science and resources, Jiangnan University, Wuxi, Jiangsu 214122, P. R China","institution_ids":["https://openalex.org/I111599522"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I111599522"],"apc_list":null,"apc_paid":null,"fwci":7.7317,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.97936021,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"16","issue":"5","first_page":"2057","last_page":"2072"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10365","display_name":"Gastrointestinal motility and disorders","score":0.9872999787330627,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.010599999688565731,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/slow-transit-constipation","display_name":"slow transit constipation","score":0.9610000252723694},{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":0.8600000143051147},{"id":"https://openalex.org/keywords/bdnf-trkb-signaling","display_name":"BDNF/TrkB signaling","score":0.8820000290870667},{"id":"https://openalex.org/keywords/intestinal-innervation","display_name":"intestinal innervation","score":0.6499999761581421},{"id":"https://openalex.org/keywords/intestinal-barrier","display_name":"intestinal barrier","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C2778641530","wikidata":"https://www.wikidata.org/wiki/Q2902072","display_name":"Bifidobacterium bifidum","level":5,"score":0.9535597562789917},{"id":"https://openalex.org/C71527416","wikidata":"https://www.wikidata.org/wiki/Q3774852","display_name":"Cathartic","level":2,"score":0.5334394574165344},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.423020601272583},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.347555935382843},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32305362820625305},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3195202350616455},{"id":"https://openalex.org/C2780305828","wikidata":"https://www.wikidata.org/wiki/Q132656","display_name":"Bifidobacterium","level":4,"score":0.19196593761444092},{"id":"https://openalex.org/C2780206646","wikidata":"https://www.wikidata.org/wiki/Q1061596","display_name":"Lactobacillus","level":3,"score":0.17332947254180908},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.10305199027061462},{"id":"https://openalex.org/C100544194","wikidata":"https://www.wikidata.org/wiki/Q41760","display_name":"Fermentation","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000069196","descriptor_name":"Gastrointestinal Microbiome","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000069985","descriptor_name":"Bifidobacterium bifidum","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003106","descriptor_name":"Colon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003248","descriptor_name":"Constipation","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D003248","descriptor_name":"Constipation","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D003248","descriptor_name":"Constipation","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005243","descriptor_name":"Feces","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D019208","descriptor_name":"Brain-Derived Neurotrophic Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D020813","descriptor_name":"Receptor, trkB","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D020813","descriptor_name":"Receptor, trkB","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1039/d4fo05835f","doi":"https://doi.org/10.1039/d4fo05835f","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d4fo05835f","pdf_url":null,"source":{"id":"https://openalex.org/S2483688756","display_name":"Food & Function","issn_l":"2042-6496","issn":["2042-6496","2042-650X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food & Function","raw_type":"journal-article"},{"id":"pmid:39963068","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39963068","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Food & function","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2745069739","display_name":null,"funder_award_id":"32172213","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G694732805","display_name":null,"funder_award_id":"2022B111107006","funder_id":"https://openalex.org/F4320336405","funder_display_name":"Special Project for Research and Development in Key areas of Guangdong Province"},{"id":"https://openalex.org/G8459128685","display_name":null,"funder_award_id":"332394051","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320336359","display_name":"Collaborative Innovationcenter of Food Safety and Quality Control in Jiangsu Province","ror":"https://ror.org/01cvdks57"},{"id":"https://openalex.org/F4320336405","display_name":"Special Project for Research and Development in Key areas of Guangdong Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W1591153814","https://openalex.org/W1975906041","https://openalex.org/W1981367331","https://openalex.org/W2017376904","https://openalex.org/W2021503256","https://openalex.org/W2028350150","https://openalex.org/W2042293357","https://openalex.org/W2056250989","https://openalex.org/W2080433636","https://openalex.org/W2093694233","https://openalex.org/W2098173070","https://openalex.org/W2109491705","https://openalex.org/W2110048015","https://openalex.org/W2133808995","https://openalex.org/W2160904230","https://openalex.org/W2409656339","https://openalex.org/W2414130417","https://openalex.org/W2468315138","https://openalex.org/W2511184432","https://openalex.org/W2531099443","https://openalex.org/W2532703344","https://openalex.org/W2546645949","https://openalex.org/W2575984858","https://openalex.org/W2592458260","https://openalex.org/W2623796068","https://openalex.org/W2744370763","https://openalex.org/W2750390448","https://openalex.org/W2751377729","https://openalex.org/W2790264800","https://openalex.org/W2807772034","https://openalex.org/W2893955328","https://openalex.org/W2897699153","https://openalex.org/W2902161130","https://openalex.org/W2939731554","https://openalex.org/W2963419343","https://openalex.org/W2971991233","https://openalex.org/W2991014765","https://openalex.org/W3004904380","https://openalex.org/W3014168254","https://openalex.org/W3022623001","https://openalex.org/W3028332131","https://openalex.org/W3032932190","https://openalex.org/W3037610538","https://openalex.org/W3109671945","https://openalex.org/W3111799587","https://openalex.org/W3122372150","https://openalex.org/W3129721376","https://openalex.org/W3137619127","https://openalex.org/W3155099403","https://openalex.org/W3175256745","https://openalex.org/W3180833149","https://openalex.org/W3185881008","https://openalex.org/W3186544027","https://openalex.org/W3200710341","https://openalex.org/W4200016209","https://openalex.org/W4205663465","https://openalex.org/W4205765264","https://openalex.org/W4206254938","https://openalex.org/W4282822830","https://openalex.org/W4285389795","https://openalex.org/W4293168835","https://openalex.org/W4296744941","https://openalex.org/W4300222524","https://openalex.org/W4321189568","https://openalex.org/W4322503088","https://openalex.org/W4365519945","https://openalex.org/W4366984915","https://openalex.org/W4375951217","https://openalex.org/W4386250989","https://openalex.org/W4391027516","https://openalex.org/W4401996871","https://openalex.org/W4403468106"],"related_works":["https://openalex.org/W4322503088","https://openalex.org/W4404729231","https://openalex.org/W4404670546","https://openalex.org/W4405453954","https://openalex.org/W6958708920","https://openalex.org/W7165728844","https://openalex.org/W4386153227","https://openalex.org/W4205765264","https://openalex.org/W2888658977","https://openalex.org/W4409182769"],"abstract_inverted_index":{"Cathartic":[0],"colon":[1],"(CC)":[2],"is":[3],"a":[4,11,20],"type":[5],"of":[6,15],"slow-transit":[7],"constipation":[8],"caused":[9],"by":[10],"patient's":[12],"long-term":[13],"use":[14],"irritating":[16],"laxatives.":[17],"Probiotics":[18],"play":[19],"crucial":[21],"role":[22],"in":[23],"managing":[24],"constipation.":[25]},"counts_by_year":[{"year":2026,"cited_by_count":9},{"year":2025,"cited_by_count":6}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2025-02-07T00:00:00"}