{"id":"https://openalex.org/W4407122000","doi":"https://doi.org/10.1016/j.jddst.2025.106686","title":"MPPD modeling based differential lung dosimetry of rifabutin loaded \u03b2-glucan dry powder microparticles in adult mice and various human age groups","display_name":"MPPD modeling based differential lung dosimetry of rifabutin loaded \u03b2-glucan dry powder microparticles in adult mice and various human age groups","publication_year":2025,"publication_date":"2025-02-04","ids":{"openalex":"https://openalex.org/W4407122000","doi":"https://doi.org/10.1016/j.jddst.2025.106686"},"language":"en","primary_location":{"id":"doi:10.1016/j.jddst.2025.106686","doi":"https://doi.org/10.1016/j.jddst.2025.106686","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2025.106686","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084005808","display_name":"D. Anshita","orcid":"https://orcid.org/0000-0002-5364-4710","observed_orcids":["https://orcid.org/0000-0002-5364-4710"]},"institutions":[{"id":"https://openalex.org/I66760702","display_name":"Council of Scientific and Industrial Research","ror":"https://ror.org/021wm7p51","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]},{"id":"https://openalex.org/I85145500","display_name":"Indian Institute of Toxicology Research","ror":"https://ror.org/01e70mw69","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702","https://openalex.org/I85145500"]},{"id":"https://openalex.org/I99364266","display_name":"Academy of Scientific and Innovative Research","ror":"https://ror.org/053rcsq61","country_code":"IN","type":"education","lineage":["https://openalex.org/I99364266"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Anshita","raw_affiliation_strings":["Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, UP, India","Inhalation Toxicology Facility, REACT Division, CSIR- Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, P.B. No. 80, Lucknow, 226001, UP, India"],"raw_orcid":"https://orcid.org/0000-0002-5364-4710","affiliations":[{"raw_affiliation_string":"Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, UP, India","institution_ids":["https://openalex.org/I99364266"]},{"raw_affiliation_string":"Inhalation Toxicology Facility, REACT Division, CSIR- Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, P.B. No. 80, Lucknow, 226001, UP, India","institution_ids":["https://openalex.org/I66760702","https://openalex.org/I85145500"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001348137","display_name":"Vyas Kumar","orcid":"https://orcid.org/0000-0002-5910-5849","observed_orcids":["https://orcid.org/0000-0002-5910-5849"]},"institutions":[{"id":"https://openalex.org/I66760702","display_name":"Council of Scientific and Industrial Research","ror":"https://ror.org/021wm7p51","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]},{"id":"https://openalex.org/I85145500","display_name":"Indian Institute of Toxicology Research","ror":"https://ror.org/01e70mw69","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702","https://openalex.org/I85145500"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vyas Kumar","raw_affiliation_strings":["Inhalation Toxicology Facility, REACT Division, CSIR- Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, P.B. No. 80, Lucknow, 226001, UP, India"],"raw_orcid":"https://orcid.org/0000-0002-5910-5849","affiliations":[{"raw_affiliation_string":"Inhalation Toxicology Facility, REACT Division, CSIR- Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, P.B. No. 80, Lucknow, 226001, UP, India","institution_ids":["https://openalex.org/I66760702","https://openalex.org/I85145500"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Firoz Ahmad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I115475287","display_name":"Oklahoma State University","ror":"https://ror.org/01g9vbr38","country_code":"US","type":"education","lineage":["https://openalex.org/I115475287"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Firoz Ahmad","raw_affiliation_strings":["Department of Physiological Sciences, Oklahoma Centre for Respiratory and Infectious Diseases, Oklahoma State University, OK, 74078, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiological Sciences, Oklahoma Centre for Respiratory and Infectious Diseases, Oklahoma State University, OK, 74078, USA","institution_ids":["https://openalex.org/I115475287"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044579043","display_name":"Mohd Khubaib","orcid":"https://orcid.org/0000-0002-3304-1891","observed_orcids":["https://orcid.org/0000-0002-3304-1891"]},"institutions":[{"id":"https://openalex.org/I189949046","display_name":"Integral University","ror":"https://ror.org/039zd5s34","country_code":"IN","type":"education","lineage":["https://openalex.org/I189949046"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mohd Khubaib","raw_affiliation_strings":["Department of Biosciences, Integral University, Lucknow, 226026, UP, India"],"raw_orcid":"https://orcid.org/0000-0002-3304-1891","affiliations":[{"raw_affiliation_string":"Department of Biosciences, Integral University, Lucknow, 226026, UP, India","institution_ids":["https://openalex.org/I189949046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080134794","display_name":"Rolee Sharma","orcid":"https://orcid.org/0000-0002-1944-1549","observed_orcids":["https://orcid.org/0000-0002-1944-1549"]},"institutions":[{"id":"https://openalex.org/I229991691","display_name":"Chhatrapati Shahu Ji Maharaj University","ror":"https://ror.org/040qxz868","country_code":"IN","type":"education","lineage":["https://openalex.org/I229991691"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Rolee Sharma","raw_affiliation_strings":["Department of Life Sciences & Biotechnology, Chhatrapati Shahu Ji Maharaj University, Kanpur, UP, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Sciences & Biotechnology, Chhatrapati Shahu Ji Maharaj University, Kanpur, UP, India","institution_ids":["https://openalex.org/I229991691"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101619115","display_name":"Jyotsna Singh","orcid":"https://orcid.org/0000-0002-3686-0585","observed_orcids":["https://orcid.org/0000-0002-3686-0585"]},"institutions":[{"id":"https://openalex.org/I66760702","display_name":"Council of Scientific and Industrial Research","ror":"https://ror.org/021wm7p51","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702"]},{"id":"https://openalex.org/I85145500","display_name":"Indian Institute of Toxicology Research","ror":"https://ror.org/01e70mw69","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210134808","https://openalex.org/I66760702","https://openalex.org/I85145500"]},{"id":"https://openalex.org/I99364266","display_name":"Academy of Scientific and Innovative Research","ror":"https://ror.org/053rcsq61","country_code":"IN","type":"education","lineage":["https://openalex.org/I99364266"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Jyotsna Singh","raw_affiliation_strings":["Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, UP, India","Inhalation Toxicology Facility, REACT Division, CSIR- Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, P.B. No. 80, Lucknow, 226001, UP, India"],"raw_orcid":"https://orcid.org/0000-0002-3686-0585","affiliations":[{"raw_affiliation_string":"Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, UP, India","institution_ids":["https://openalex.org/I99364266"]},{"raw_affiliation_string":"Inhalation Toxicology Facility, REACT Division, CSIR- Indian Institute of Toxicology Research, Vishvigyan Bhawan, 31, Mahatma Gandhi Marg, P.B. No. 80, Lucknow, 226001, UP, India","institution_ids":["https://openalex.org/I66760702","https://openalex.org/I85145500"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101619115"],"corresponding_institution_ids":["https://openalex.org/I66760702","https://openalex.org/I85145500","https://openalex.org/I99364266"],"apc_list":{"value":3810,"currency":"USD","value_usd":3810},"apc_paid":null,"fwci":2.9361,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.90345985,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"106","issue":null,"first_page":"106686","last_page":"106686"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11651","display_name":"Inhalation and Respiratory Drug Delivery","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rifabutin","display_name":"rifabutin","score":0.9940000176429749},{"id":"https://openalex.org/keywords/lung-dosimetry","display_name":"lung dosimetry","score":0.7239999771118164},{"id":"https://openalex.org/keywords/particle-deposition","display_name":"particle deposition","score":0.7139999866485596},{"id":"https://openalex.org/keywords/particle-clearance","display_name":"particle clearance","score":0.8140000104904175},{"id":"https://openalex.org/keywords/cross-species-comparison","display_name":"cross-species comparison","score":0.6800000071525574},{"id":"https://openalex.org/keywords/age-differences","display_name":"age differences","score":0.5350000262260437},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6480000019073486},{"id":"https://openalex.org/keywords/alveolar-macrophages","display_name":"alveolar macrophages","score":0.9039999842643738},{"id":"https://openalex.org/keywords/aerosol-drug-delivery","display_name":"aerosol drug delivery","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C2780867798","wikidata":"https://www.wikidata.org/wiki/Q1135705","display_name":"Rifabutin","level":4,"score":0.7190277576446533},{"id":"https://openalex.org/C75088862","wikidata":"https://www.wikidata.org/wiki/Q2291081","display_name":"Dosimetry","level":2,"score":0.5045207738876343},{"id":"https://openalex.org/C2779744229","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Human lung","level":3,"score":0.4925132691860199},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.48072341084480286},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.44780269265174866},{"id":"https://openalex.org/C2776123893","wikidata":"https://www.wikidata.org/wiki/Q416796","display_name":"Glucan","level":2,"score":0.42683878540992737},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.4230373501777649},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4004823565483093},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.337840735912323},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.28596436977386475},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.28208744525909424},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.20078423619270325},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1482471227645874},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14224281907081604},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11601322889328003},{"id":"https://openalex.org/C2776962512","wikidata":"https://www.wikidata.org/wiki/Q118551","display_name":"Clarithromycin","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jddst.2025.106686","doi":"https://doi.org/10.1016/j.jddst.2025.106686","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2025.106686","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9789000153541565,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G7038247484","display_name":null,"funder_award_id":"CRG/2019/007035","funder_id":"https://openalex.org/F4320320719","funder_display_name":"Department of Science and Technology, Ministry of Science and Technology, India"}],"funders":[{"id":"https://openalex.org/F2416548153","display_name":"CSIR-Indian Institute of Toxicology Research, Government of India","ror":null},{"id":"https://openalex.org/F4320320719","display_name":"Department of Science and Technology, Ministry of Science and Technology, India","ror":"https://ror.org/0101xrq71"},{"id":"https://openalex.org/F4320320721","display_name":"Council of Scientific and Industrial Research, India","ror":"https://ror.org/021wm7p51"},{"id":"https://openalex.org/F4320325345","display_name":"Council of Science and Technology, U.P.","ror":"https://ror.org/01y25zv73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1986524556","https://openalex.org/W1998944697","https://openalex.org/W2003905661","https://openalex.org/W2027342181","https://openalex.org/W2032584053","https://openalex.org/W2034866630","https://openalex.org/W2047220877","https://openalex.org/W2053557804","https://openalex.org/W2078671329","https://openalex.org/W2092413816","https://openalex.org/W2109216016","https://openalex.org/W2124306231","https://openalex.org/W2128921449","https://openalex.org/W2143478697","https://openalex.org/W2157782849","https://openalex.org/W2163797903","https://openalex.org/W2170637707","https://openalex.org/W2344665871","https://openalex.org/W2469608520","https://openalex.org/W2493444967","https://openalex.org/W2560614715","https://openalex.org/W2746155660","https://openalex.org/W2751774187","https://openalex.org/W2767011191","https://openalex.org/W2791442541","https://openalex.org/W2807336891","https://openalex.org/W2921248422","https://openalex.org/W2989656336","https://openalex.org/W3042445400","https://openalex.org/W3081171779","https://openalex.org/W3081708038","https://openalex.org/W3084317835","https://openalex.org/W3134223777","https://openalex.org/W3136615322","https://openalex.org/W3142413066","https://openalex.org/W3174565507","https://openalex.org/W3209353855","https://openalex.org/W4225096580","https://openalex.org/W4242360047","https://openalex.org/W4283385384","https://openalex.org/W4290700360","https://openalex.org/W4321611156","https://openalex.org/W4381855985","https://openalex.org/W4386565953","https://openalex.org/W4390146497","https://openalex.org/W4390442267","https://openalex.org/W4390696407","https://openalex.org/W4390935948","https://openalex.org/W4393931012","https://openalex.org/W4400682781","https://openalex.org/W4401033094"],"related_works":["https://openalex.org/W256515941","https://openalex.org/W2304970015","https://openalex.org/W2286161743","https://openalex.org/W3151488112","https://openalex.org/W2155146282","https://openalex.org/W2163156439","https://openalex.org/W2626679715","https://openalex.org/W4238998491","https://openalex.org/W2417357751","https://openalex.org/W3040972647"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}