{"id":"https://openalex.org/W4406423969","doi":"https://doi.org/10.3390/jcm14020525","title":"Supervised or Home-Based? Exploring the Best Exercise Approach for Knee Osteoarthritis Management: A Systematic Review and Meta-Analysis","display_name":"Supervised or Home-Based? Exploring the Best Exercise Approach for Knee Osteoarthritis Management: A Systematic Review and Meta-Analysis","publication_year":2025,"publication_date":"2025-01-15","ids":{"openalex":"https://openalex.org/W4406423969","doi":"https://doi.org/10.3390/jcm14020525","pmid":"https://pubmed.ncbi.nlm.nih.gov/39860530","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11765608"},"language":"en","primary_location":{"id":"doi:10.3390/jcm14020525","doi":"https://doi.org/10.3390/jcm14020525","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14020525","pdf_url":"https://www.mdpi.com/2077-0383/14/2/525/pdf?version=1736940411","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2077-0383/14/2/525/pdf?version=1736940411","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056343669","display_name":"Jean Mapinduzi","orcid":"https://orcid.org/0000-0002-6016-9786","observed_orcids":["https://orcid.org/0000-0002-6016-9786"]},"institutions":[{"id":"https://openalex.org/I2800696149","display_name":"Republic of Burundi","ror":"https://ror.org/02vz62k77","country_code":"BI","type":"government","lineage":["https://openalex.org/I2800696149"]},{"id":"https://openalex.org/I4405260641","display_name":"Institut National de sante publique","ror":"https://ror.org/042sjvf54","country_code":"BI","type":"education","lineage":["https://openalex.org/I4405260641"]},{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE","BI"],"is_corresponding":true,"raw_author_name":"Jean Mapinduzi","raw_affiliation_strings":["Cabinet de Kin\u00e9sith\u00e9rapie et d\u2019Appareillage Orthop\u00e9dique (CKAO-AMAHORO), Bujumbura 6807, Burundi","REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, University of Hasselt, 3590 Diepenbeek, Belgium","TechnoRehab Lab, Fili\u00e8re de Kin\u00e9sith\u00e9rapie et R\u00e9adaptation, D\u00e9partement des Sciences Cliniques, Institut National de Sant\u00e9 Publique (INSP), Bujumbura 6807, Burundi","Technology-Supported and Data Driven Rehabilitation, Data Science Institute, University of Hasselt, 3590 Diepenbeek, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cabinet de Kin\u00e9sith\u00e9rapie et d\u2019Appareillage Orthop\u00e9dique (CKAO-AMAHORO), Bujumbura 6807, Burundi","institution_ids":["https://openalex.org/I2800696149"]},{"raw_affiliation_string":"REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, University of Hasselt, 3590 Diepenbeek, Belgium","institution_ids":["https://openalex.org/I878454856"]},{"raw_affiliation_string":"TechnoRehab Lab, Fili\u00e8re de Kin\u00e9sith\u00e9rapie et R\u00e9adaptation, D\u00e9partement des Sciences Cliniques, Institut National de Sant\u00e9 Publique (INSP), Bujumbura 6807, Burundi","institution_ids":["https://openalex.org/I4405260641"]},{"raw_affiliation_string":"Technology-Supported and Data Driven Rehabilitation, Data Science Institute, University of Hasselt, 3590 Diepenbeek, Belgium","institution_ids":["https://openalex.org/I878454856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029331963","display_name":"G\u00e9rard Ndacayisaba","orcid":"https://orcid.org/0000-0003-3562-3008","observed_orcids":["https://orcid.org/0000-0003-3562-3008"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G\u00e9rard Ndacayisaba","raw_affiliation_strings":["Centre National de R\u00e9f\u00e9rence en Kin\u00e9sith\u00e9rapie et R\u00e9adaptation M\u00e9dicale (CNRKR), Bujumbura 6807, Burundi"],"raw_orcid":"https://orcid.org/0000-0003-3562-3008","affiliations":[{"raw_affiliation_string":"Centre National de R\u00e9f\u00e9rence en Kin\u00e9sith\u00e9rapie et R\u00e9adaptation M\u00e9dicale (CNRKR), Bujumbura 6807, Burundi","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081864308","display_name":"Penielle Mahutchegnon Mitcha\u03ca","orcid":"https://orcid.org/0000-0003-2136-8229","observed_orcids":["https://orcid.org/0000-0003-2136-8229"]},"institutions":[{"id":"https://openalex.org/I4210113655","display_name":"Universit\u00e9 de Parakou","ror":"https://ror.org/025wndx93","country_code":"BJ","type":"education","lineage":["https://openalex.org/I4210113655"]}],"countries":["BJ"],"is_corresponding":false,"raw_author_name":"Penielle Mahutchegnon Mitcha\u03ca","raw_affiliation_strings":["Ecole Nationale de Sant\u00e9 Publique et de Surveillance Epid\u00e9miologique (ENATSE), Universit\u00e9 de Parakou, Parakou 03 BP 10, Benin"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ecole Nationale de Sant\u00e9 Publique et de Surveillance Epid\u00e9miologique (ENATSE), Universit\u00e9 de Parakou, Parakou 03 BP 10, Benin","institution_ids":["https://openalex.org/I4210113655"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041031012","display_name":"Oy\u00e9n\u00e9 Kossi","orcid":"https://orcid.org/0000-0001-9117-7191","observed_orcids":["https://orcid.org/0000-0001-9117-7191"]},"institutions":[{"id":"https://openalex.org/I4210113655","display_name":"Universit\u00e9 de Parakou","ror":"https://ror.org/025wndx93","country_code":"BJ","type":"education","lineage":["https://openalex.org/I4210113655"]}],"countries":["BJ"],"is_corresponding":false,"raw_author_name":"Oy\u00e9n\u00e9 Kossi","raw_affiliation_strings":["Ecole Nationale de Sant\u00e9 Publique et de Surveillance Epid\u00e9miologique (ENATSE), Universit\u00e9 de Parakou, Parakou 03 BP 10, Benin"],"raw_orcid":"https://orcid.org/0000-0001-9117-7191","affiliations":[{"raw_affiliation_string":"Ecole Nationale de Sant\u00e9 Publique et de Surveillance Epid\u00e9miologique (ENATSE), Universit\u00e9 de Parakou, Parakou 03 BP 10, Benin","institution_ids":["https://openalex.org/I4210113655"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080392562","display_name":"Bruno Bonnech\u00e8re","orcid":"https://orcid.org/0000-0002-7729-4700","observed_orcids":["https://orcid.org/0000-0002-7729-4700"]},"institutions":[{"id":"https://openalex.org/I4210130715","display_name":"Hogeschool PXL","ror":"https://ror.org/03qsbr555","country_code":"BE","type":"education","lineage":["https://openalex.org/I4210130715"]},{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Bruno Bonnech\u00e8re","raw_affiliation_strings":["Department of PXL-Healthcare, PXL University of Applied Sciences and Arts, 3500 Hasselt, Belgium","REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, University of Hasselt, 3590 Diepenbeek, Belgium","Technology-Supported and Data Driven Rehabilitation, Data Science Institute, University of Hasselt, 3590 Diepenbeek, Belgium"],"raw_orcid":"https://orcid.org/0000-0002-7729-4700","affiliations":[{"raw_affiliation_string":"Department of PXL-Healthcare, PXL University of Applied Sciences and Arts, 3500 Hasselt, Belgium","institution_ids":["https://openalex.org/I4210130715"]},{"raw_affiliation_string":"REVAL Rehabilitation Research Center, Faculty of Rehabilitation Sciences, University of Hasselt, 3590 Diepenbeek, Belgium","institution_ids":["https://openalex.org/I878454856"]},{"raw_affiliation_string":"Technology-Supported and Data Driven Rehabilitation, Data Science Institute, University of Hasselt, 3590 Diepenbeek, Belgium","institution_ids":["https://openalex.org/I878454856"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5056343669"],"corresponding_institution_ids":["https://openalex.org/I2800696149","https://openalex.org/I4405260641","https://openalex.org/I878454856"],"apc_list":{"value":2600,"currency":"CHF","value_usd":3137},"apc_paid":{"value":2600,"currency":"CHF","value_usd":3137},"fwci":2.2239,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.89047195,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"14","issue":"2","first_page":"525","last_page":"525"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.573199987411499,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation","score":0.573199987411499,"subfield":{"id":"https://openalex.org/subfields/3612","display_name":"Physical Therapy, Sports Therapy and Rehabilitation"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10105","display_name":"Osteoarthritis Treatment and Mechanisms","score":0.385699987411499,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/knee-osteoarthritis","display_name":"knee osteoarthritis","score":1.0},{"id":"https://openalex.org/keywords/home-based-exercise","display_name":"home-based exercise","score":0.9089999794960022},{"id":"https://openalex.org/keywords/supervised-exercise","display_name":"supervised exercise","score":0.9509999752044678},{"id":"https://openalex.org/keywords/exercise-therapy","display_name":"exercise therapy","score":0.9570000171661377},{"id":"https://openalex.org/keywords/pain","display_name":"pain","score":0.703000009059906},{"id":"https://openalex.org/keywords/disability","display_name":"disability","score":0.7369999885559082},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.652999997138977},{"id":"https://openalex.org/keywords/cost-effectiveness","display_name":"cost-effectiveness","score":0.7009999752044678}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9316985011100769},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.7233016490936279},{"id":"https://openalex.org/C95190672","wikidata":"https://www.wikidata.org/wiki/Q815382","display_name":"Meta-analysis","level":2,"score":0.6954925656318665},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6420358419418335},{"id":"https://openalex.org/C2776478404","wikidata":"https://www.wikidata.org/wiki/Q1105187","display_name":"Cochrane Library","level":3,"score":0.614992082118988},{"id":"https://openalex.org/C2776164576","wikidata":"https://www.wikidata.org/wiki/Q62736","display_name":"Osteoarthritis","level":3,"score":0.5625085830688477},{"id":"https://openalex.org/C2778818304","wikidata":"https://www.wikidata.org/wiki/Q1819478","display_name":"Rehabilitation","level":2,"score":0.542978048324585},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.4815159738063812},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.47320717573165894},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.41175079345703125},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.21004921197891235},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1292618215084076},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10055908560752869},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.06688651442527771},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/jcm14020525","doi":"https://doi.org/10.3390/jcm14020525","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14020525","pdf_url":"https://www.mdpi.com/2077-0383/14/2/525/pdf?version=1736940411","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11765608","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11765608","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11765608/pdf/jcm-14-00525.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Med","raw_type":"Text"},{"id":"pmid:39860530","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39860530","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of clinical medicine","raw_type":"Journal Article"},{"id":"pmh:oai:documentserver.uhasselt.be:1942/45334","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1942/45334","pdf_url":"https://documentserver.uhasselt.be//bitstream/1942/45334/1/Supervised%20or%20Home-Based.pdf","source":{"id":"https://openalex.org/S4306401926","display_name":"Document Server@UHasselt (UHasselt)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I878454856","host_organization_name":"Hasselt University","host_organization_lineage":["https://openalex.org/I878454856"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/review"}],"best_oa_location":{"id":"doi:10.3390/jcm14020525","doi":"https://doi.org/10.3390/jcm14020525","is_oa":true,"landing_page_url":"https://doi.org/10.3390/jcm14020525","pdf_url":"https://www.mdpi.com/2077-0383/14/2/525/pdf?version=1736940411","source":{"id":"https://openalex.org/S2737969411","display_name":"Journal of Clinical Medicine","issn_l":"2077-0383","issn":["2077-0383"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","ki-jl-1","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"},{"display_name":"Meta-Analysis","id":"https://openalex.org/study-designs/meta-analysis"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4406423969.pdf","grobid_xml":"https://content.openalex.org/works/W4406423969.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W997324159","https://openalex.org/W1616537603","https://openalex.org/W1690679646","https://openalex.org/W1840491359","https://openalex.org/W1976522305","https://openalex.org/W1986901061","https://openalex.org/W1990721014","https://openalex.org/W2006623794","https://openalex.org/W2013904927","https://openalex.org/W2018004536","https://openalex.org/W2028469883","https://openalex.org/W2029361033","https://openalex.org/W2032664213","https://openalex.org/W2068875355","https://openalex.org/W2084292255","https://openalex.org/W2089294537","https://openalex.org/W2102968146","https://openalex.org/W2114362978","https://openalex.org/W2118947871","https://openalex.org/W2119605658","https://openalex.org/W2127818482","https://openalex.org/W2132406084","https://openalex.org/W2136434876","https://openalex.org/W2147967828","https://openalex.org/W2167381496","https://openalex.org/W2344364513","https://openalex.org/W2506937591","https://openalex.org/W2526568664","https://openalex.org/W2577543962","https://openalex.org/W2593866534","https://openalex.org/W2741060451","https://openalex.org/W2885204112","https://openalex.org/W2902833505","https://openalex.org/W2905009123","https://openalex.org/W2914629705","https://openalex.org/W2945870087","https://openalex.org/W2963570379","https://openalex.org/W2972861740","https://openalex.org/W2974146296","https://openalex.org/W2979750401","https://openalex.org/W2989316744","https://openalex.org/W3019492115","https://openalex.org/W3092088135","https://openalex.org/W3119762460","https://openalex.org/W3128653999","https://openalex.org/W3138716502","https://openalex.org/W3179019226","https://openalex.org/W3183455096","https://openalex.org/W3216554420","https://openalex.org/W4211067786","https://openalex.org/W4232058719","https://openalex.org/W4286215738","https://openalex.org/W4293222266","https://openalex.org/W4294215472","https://openalex.org/W4297265545","https://openalex.org/W4317821225","https://openalex.org/W4378229366","https://openalex.org/W4387163965","https://openalex.org/W4390488654","https://openalex.org/W4390769996","https://openalex.org/W4391747150","https://openalex.org/W4400106121","https://openalex.org/W4400268165","https://openalex.org/W4401703715"],"related_works":["https://openalex.org/W4320033922","https://openalex.org/W2093507393","https://openalex.org/W4317705244","https://openalex.org/W7220468101","https://openalex.org/W4392816364","https://openalex.org/W7217993760","https://openalex.org/W7009388080","https://openalex.org/W4400050962","https://openalex.org/W2741060451","https://openalex.org/W4409009610"],"abstract_inverted_index":{"Background/Objective:":[0],"Knee":[1],"osteoarthritis":[2],"(OA)":[3],"is":[4,25],"a":[5,99,204],"common":[6],"and":[7,18,35,57,73,84,98,140,166,193],"debilitating":[8],"condition":[9],"affecting":[10],"older":[11],"adults,":[12],"often":[13],"progressing":[14],"to":[15,51,103,121,135,144,179,202,212],"advanced":[16],"stages":[17],"requiring":[19],"total":[20],"joint":[21],"replacement.":[22],"Exercise":[23],"therapy":[24],"widely":[26],"recognized":[27],"as":[28],"the":[29,33,44,92,105,183,191],"first-line":[30],"approach":[31],"for":[32],"prevention":[34],"initial":[36],"management":[37],"of":[38,46,69,107,185,195,197],"OA.":[39,64],"This":[40],"systematic":[41,67],"review":[42],"assessed":[43],"effectiveness":[45],"home-based":[47],"exercises":[48,53,149,187],"(HBEs)":[49],"compared":[50,178],"supervised":[52,139,148,186],"in":[54,119,154],"alleviating":[55],"pain":[56,155],"reducing":[58],"disability":[59,167],"among":[60],"patients":[61,115],"with":[62],"knee":[63],"Methods:":[65],"A":[66],"search":[68],"PubMed,":[70],"Cochrane":[71],"Library,":[72],"ScienceDirect":[74],"identified":[75],"randomized":[76],"controlled":[77],"trials":[78],"(RCTs)":[79],"published":[80],"between":[81],"January":[82],"2001":[83],"October":[85],"2024.":[86],"Methodological":[87],"quality":[88,124],"was":[89,101],"evaluated":[90],"using":[91],"Physiotherapy":[93],"Evidence":[94],"Database":[95],"(PEDro)":[96],"scale,":[97],"meta-analysis":[100],"conducted":[102],"quantify":[104],"efficacy":[106],"these":[108],"interventions.":[109],"Results:":[110],"Ten":[111],"RCTs":[112],"involving":[113],"917":[114],"were":[116,142],"included,":[117],"ranging":[118],"moderate":[120],"high":[122],"methodological":[123],"(PEDro":[125],"score:":[126],"6.3":[127],"\u00b1":[128],"1.2).":[129],"Intervention":[130],"durations":[131],"ranged":[132],"from":[133],"4":[134],"12":[136],"weeks.":[137],"Both":[138],"HBEs":[141],"found":[143],"be":[145],"effective,":[146],"but":[147],"demonstrated":[150],"statistically":[151],"significant":[152],"improvements":[153],"(SMD":[156,168],"=":[157,164,169],"\u22120.45":[158],"[95%":[159,171],"CI":[160,172],"\u22120.79;":[161],"\u22120.11],":[162],"p":[163,175],"0.015)":[165],"\u22120.28":[170],"\u22120.42;":[173],"\u22120.14],":[174],"<":[176],"0.001)":[177],"HBEs.":[180],"Conclusions:":[181],"Despite":[182],"superiority":[184],"over":[188],"HBEs,":[189,198],"considering":[190],"cost-effectiveness":[192],"ease":[194],"implementation":[196],"we":[199],"developed":[200],"recommendations":[201],"create":[203],"hybrid":[205],"rehabilitation":[206],"program":[207],"that":[208],"combines":[209],"both":[210],"approaches":[211],"maximize":[213],"clinical":[214],"outcomes.":[215]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2025-01-16T00:00:00"}